4N9F3

Crystal structure of the vif-cbfbeta-cul5-elob-eloc pentameric complex
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
309
structure length
295
Chain Sequence
ASLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif
rcsb
molecule tags Ligase/viral protein
source organism Homo sapiens
molecule keywords Cullin-5
total genus 102
structure length 295
sequence length 309
chains with identical sequence 9, C, I, O, U, V, f, l, r, w, x
ec nomenclature
pdb deposition date 2013-10-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4n9f301
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4n9f302
1U6GA 4WQOD 1LDKB 3DPLC 4HXIB 4EOZB 4P5OA 3DQVC 4N9F3 4A64A 2WZKA 4JGHD 4APFB 4AP2B 3RTRA 4F52A 1LDKA 1LDJA
chains in the Genus database with same CATH superfamily
1LDKA 3DQVC 4NUVA 4F52A 4WQOD 2WAUA 4EOZB 2XU0A 3BQKA 4YFSA 4AP2B 3CMLA 2Y8DA 2PFVA 1LDJA 1LDKB 3CPZA 5F3JA 4A64A 3RRCA 4APFB 2B1EA 1U6GA 3DPLC 3BQIA 4HXIB 4NUUA 4P5OA 2WZKA 4JGHD 3RTRA 3BQLA 4N9F3
chains in the Genus database with same CATH topology
1U6GA 4WQOD 1LDKB 3DPLC 4HXIB 4EOZB 4P5OA 3DQVC 4N9F3 4A64A 2WZKA 4JGHD 4APFB 4AP2B 3RTRA 4F52A 1LDKA 1LDJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U6G A;  4WQO D;  1LDK B;  3DPL C;  4HXI B;  4EOZ B;  4P5O A;  3DQV C;  4N9F 3;  4A64 A;  2WZK A;  4JGH D;  4APF B;  4AP2 B;  3RTR A;  4F52 A;  1LDK A;  1LDJ A; 
#chains in the Genus database with same CATH topology
 1LDK A;  3DQV C;  4NUV A;  4F52 A;  4WQO D;  2WAU A;  4EOZ B;  2XU0 A;  3BQK A;  4YFS A;  4AP2 B;  3CML A;  2Y8D A;  2PFV A;  1LDJ A;  1LDK B;  3CPZ A;  5F3J A;  4A64 A;  3RRC A;  4APF B;  2B1E A;  1U6G A;  3DPL C;  3BQI A;  4HXI B;  4NUU A;  4P5O A;  2WZK A;  4JGH D;  3RTR A;  3BQL A;  4N9F 3; 
#chains in the Genus database with same CATH homology
 1U6G A;  4WQO D;  1LDK B;  3DPL C;  4HXI B;  4EOZ B;  4P5O A;  3DQV C;  4N9F 3;  4A64 A;  2WZK A;  4JGH D;  4APF B;  4AP2 B;  3RTR A;  4F52 A;  1LDK A;  1LDJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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