4N9F3

Crystal structure of the vif-cbfbeta-cul5-elob-eloc pentameric complex
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
309
structure length
295
Chain Sequence
ASLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif
rcsb
molecule tags Ligase/viral protein
source organism Homo sapiens
molecule keywords Cullin-5
total genus 102
structure length 295
sequence length 309
chains with identical sequence 9, C, I, O, U, V, f, l, r, w, x
ec nomenclature
pdb deposition date 2013-10-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4n9f301
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4n9f302
3DQVC 4WQOD 4N9F3 4EOZB 1LDKA 4F52A 2WZKA 1U6GA 4AP2B 3DPLC 4APFB 1LDJA 4HXIB 3RTRA 4JGHD 4A64A 4P5OA 1LDKB
chains in the Genus database with same CATH superfamily
4F52A 4NUVA 2WZKA 1U6GA 1LDJA 3BQKA 3CMLA 2PFVA 4P5OA 3DQVC 3RRCA 4N9F3 2Y8DA 4NUUA 3DPLC 4APFB 5F3JA 3CPZA 2B1EA 1LDKB 4WQOD 4EOZB 1LDKA 2XU0A 2WAUA 4AP2B 3RTRA 4A64A 3BQIA 4YFSA 3BQLA 4HXIB 4JGHD
chains in the Genus database with same CATH topology
3DQVC 4WQOD 4N9F3 4EOZB 1LDKA 4F52A 2WZKA 1U6GA 4AP2B 3DPLC 4APFB 1LDJA 4HXIB 3RTRA 4JGHD 4A64A 4P5OA 1LDKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DQV C;  4WQO D;  4N9F 3;  4EOZ B;  1LDK A;  4F52 A;  2WZK A;  1U6G A;  4AP2 B;  3DPL C;  4APF B;  1LDJ A;  4HXI B;  3RTR A;  4JGH D;  4A64 A;  4P5O A;  1LDK B; 
#chains in the Genus database with same CATH topology
 4F52 A;  4NUV A;  2WZK A;  1U6G A;  1LDJ A;  3BQK A;  3CML A;  2PFV A;  4P5O A;  3DQV C;  3RRC A;  4N9F 3;  2Y8D A;  4NUU A;  3DPL C;  4APF B;  5F3J A;  3CPZ A;  2B1E A;  1LDK B;  4WQO D;  4EOZ B;  1LDK A;  2XU0 A;  2WAU A;  4AP2 B;  3RTR A;  4A64 A;  3BQI A;  4YFS A;  3BQL A;  4HXI B;  4JGH D; 
#chains in the Genus database with same CATH homology
 3DQV C;  4WQO D;  4N9F 3;  4EOZ B;  1LDK A;  4F52 A;  2WZK A;  1U6G A;  4AP2 B;  3DPL C;  4APF B;  1LDJ A;  4HXI B;  3RTR A;  4JGH D;  4A64 A;  4P5O A;  1LDK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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