4NE3B

Human mhf1-mhf2 complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 25
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne3B02
4E45B 3B0BC 4DRBJ 4DRAE 4NE5B 4NE6B 4NE3B 4E44B
chains in the Genus database with same CATH superfamily
3LW5K 1N3SA 2LNZA 4DU6A 1N3RA 1GTPA 4NE6B 2WSEK 1EL6A 4JA3A 2WSCG 4NE3B 1WPLA 2LO0A 4DRBJ 4DRAE 3LW5G 1WURA 2WSEG 1FB1A 4QPMA 2WSFK 4E45B 1WUQA 1N3TA 2P11A 4NE5B 4R8QA 1IS7A 1WM9A 4E44B 4Q7JA 1IS8A 5DMZA 1AIPC 2PN0A 1A9CA 1A8RA 3B0BC 2WSCK 1EFUB 3VEJA 3BMBA 2KR1A 2WSFG 1FBXA 2O01G 1TFEA
chains in the Genus database with same CATH topology
1N3SA 2LNZA 4DU6A 1N3RA 1GTPA 4NE6B 1EL6A 4JA3A 1WPLA 2LO0A 4DRBJ 4DRAE 1WURA 1FB1A 4QPMA 4E45B 1WUQA 1N3TA 2P11A 4NE5B 4R8QA 1IS7A 1WM9A 4E44B 4Q7JA 1IS8A 5DMZA 1AIPC 2PN0A 1A9CA 1A8RA 3B0BC 1EFUB 3VEJA 3BMBA 2KR1A 4NE3B 1FBXA 1TFEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E45 B;  3B0B C;  4DRB J;  4DRA E;  4NE5 B;  4NE6 B;  4NE3 B;  4E44 B; 
#chains in the Genus database with same CATH topology
 3LW5 K;  1N3S A;  2LNZ A;  4DU6 A;  1N3R A;  1GTP A;  4NE6 B;  2WSE K;  1EL6 A;  4JA3 A;  2WSC G;  4NE3 B;  1WPL A;  2LO0 A;  4DRB J;  4DRA E;  3LW5 G;  1WUR A;  2WSE G;  1FB1 A;  4QPM A;  2WSF K;  4E45 B;  1WUQ A;  1N3T A;  2P11 A;  4NE5 B;  4R8Q A;  1IS7 A;  1WM9 A;  4E44 B;  4Q7J A;  1IS8 A;  5DMZ A;  1AIP C;  2PN0 A;  1A9C A;  1A8R A;  3B0B C;  2WSC K;  1EFU B;  3VEJ A;  3BMB A;  2KR1 A;  2WSF G;  1FBX A;  2O01 G;  1TFE A; 
#chains in the Genus database with same CATH homology
 1N3S A;  2LNZ A;  4DU6 A;  1N3R A;  1GTP A;  4NE6 B;  1EL6 A;  4JA3 A;  1WPL A;  2LO0 A;  4DRB J;  4DRA E;  1WUR A;  1FB1 A;  4QPM A;  4E45 B;  1WUQ A;  1N3T A;  2P11 A;  4NE5 B;  4R8Q A;  1IS7 A;  1WM9 A;  4E44 B;  4Q7J A;  1IS8 A;  5DMZ A;  1AIP C;  2PN0 A;  1A9C A;  1A8R A;  3B0B C;  1EFU B;  3VEJ A;  3BMB A;  2KR1 A;  4NE3 B;  1FBX A;  1TFE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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