4NE3B

Human mhf1-mhf2 complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Centromere protein S
total genus 25
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne3B02
4NE5B 4E44B 4NE3B 4DRBJ 4DRAE 4E45B 4NE6B 3B0BC
chains in the Genus database with same CATH superfamily
1IS8A 2WSEK 1N3RA 2LO0A 2WSFK 4E44B 2WSCG 2LNZA 5DMZA 1EFUB 1N3SA 3LW5G 4QPMA 4NE3B 2WSCK 1EL6A 4JA3A 4E45B 2O01G 4NE6B 3VEJA 3B0BC 1WM9A 1TFEA 3LW5K 1A8RA 1WURA 1FBXA 4DU6A 4DRAE 2PN0A 2KR1A 2WSEG 1FB1A 1GTPA 2WSFG 1IS7A 1AIPC 4NE5B 3BMBA 1WPLA 4DRBJ 1N3TA 4Q7JA 1A9CA 2P11A 1WUQA 4R8QA
chains in the Genus database with same CATH topology
1IS8A 1N3RA 2LO0A 4E44B 2LNZA 5DMZA 1EFUB 1N3SA 4QPMA 4NE3B 1EL6A 4JA3A 4E45B 4NE6B 3VEJA 3B0BC 1WM9A 1TFEA 1A8RA 1WURA 1FBXA 4DU6A 4DRAE 2PN0A 2KR1A 1FB1A 1GTPA 1IS7A 1AIPC 4NE5B 3BMBA 1WPLA 4DRBJ 1N3TA 4Q7JA 1A9CA 2P11A 1WUQA 4R8QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE5 B;  4E44 B;  4NE3 B;  4DRB J;  4DRA E;  4E45 B;  4NE6 B;  3B0B C; 
#chains in the Genus database with same CATH topology
 1IS8 A;  2WSE K;  1N3R A;  2LO0 A;  2WSF K;  4E44 B;  2WSC G;  2LNZ A;  5DMZ A;  1EFU B;  1N3S A;  3LW5 G;  4QPM A;  4NE3 B;  2WSC K;  1EL6 A;  4JA3 A;  4E45 B;  2O01 G;  4NE6 B;  3VEJ A;  3B0B C;  1WM9 A;  1TFE A;  3LW5 K;  1A8R A;  1WUR A;  1FBX A;  4DU6 A;  4DRA E;  2PN0 A;  2KR1 A;  2WSE G;  1FB1 A;  1GTP A;  2WSF G;  1IS7 A;  1AIP C;  4NE5 B;  3BMB A;  1WPL A;  4DRB J;  1N3T A;  4Q7J A;  1A9C A;  2P11 A;  1WUQ A;  4R8Q A; 
#chains in the Genus database with same CATH homology
 1IS8 A;  1N3R A;  2LO0 A;  4E44 B;  2LNZ A;  5DMZ A;  1EFU B;  1N3S A;  4QPM A;  4NE3 B;  1EL6 A;  4JA3 A;  4E45 B;  4NE6 B;  3VEJ A;  3B0B C;  1WM9 A;  1TFE A;  1A8R A;  1WUR A;  1FBX A;  4DU6 A;  4DRA E;  2PN0 A;  2KR1 A;  1FB1 A;  1GTP A;  1IS7 A;  1AIP C;  4NE5 B;  3BMB A;  1WPL A;  4DRB J;  1N3T A;  4Q7J A;  1A9C A;  2P11 A;  1WUQ A;  4R8Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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