4NE3B

Human mhf1-mhf2 complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 25
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne3B02
4NE5B 4NE6B 4DRBJ 4DRAE 4E45B 4NE3B 3B0BC 4E44B
chains in the Genus database with same CATH superfamily
4NE5B 2WSEG 2P11A 3B0BC 1N3TA 3LW5G 2WSCK 2WSFG 4QPMA 2KR1A 1GTPA 1WM9A 4Q7JA 3BMBA 2WSCG 2LNZA 1FBXA 1AIPC 4R8QA 1WURA 2LO0A 1A8RA 4JA3A 1WUQA 1EL6A 4DRBJ 4E45B 4DU6A 1N3RA 1EFUB 1N3SA 2O01G 4NE6B 5DMZA 3VEJA 1A9CA 1IS7A 4DRAE 2WSEK 2PN0A 1FB1A 1TFEA 1WPLA 4NE3B 2WSFK 4E44B 3LW5K 1IS8A
chains in the Genus database with same CATH topology
4NE5B 2P11A 3B0BC 1N3TA 4QPMA 2KR1A 1GTPA 1WM9A 4Q7JA 3BMBA 2LNZA 1FBXA 1AIPC 4R8QA 1WURA 2LO0A 1A8RA 4JA3A 1WUQA 1EL6A 4DRBJ 4E45B 4DU6A 1N3RA 1EFUB 1N3SA 4NE6B 5DMZA 3VEJA 1A9CA 1IS7A 4DRAE 2PN0A 1FB1A 1TFEA 1WPLA 4NE3B 4E44B 1IS8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE5 B;  4NE6 B;  4DRB J;  4DRA E;  4E45 B;  4NE3 B;  3B0B C;  4E44 B; 
#chains in the Genus database with same CATH topology
 4NE5 B;  2WSE G;  2P11 A;  3B0B C;  1N3T A;  3LW5 G;  2WSC K;  2WSF G;  4QPM A;  2KR1 A;  1GTP A;  1WM9 A;  4Q7J A;  3BMB A;  2WSC G;  2LNZ A;  1FBX A;  1AIP C;  4R8Q A;  1WUR A;  2LO0 A;  1A8R A;  4JA3 A;  1WUQ A;  1EL6 A;  4DRB J;  4E45 B;  4DU6 A;  1N3R A;  1EFU B;  1N3S A;  2O01 G;  4NE6 B;  5DMZ A;  3VEJ A;  1A9C A;  1IS7 A;  4DRA E;  2WSE K;  2PN0 A;  1FB1 A;  1TFE A;  1WPL A;  4NE3 B;  2WSF K;  4E44 B;  3LW5 K;  1IS8 A; 
#chains in the Genus database with same CATH homology
 4NE5 B;  2P11 A;  3B0B C;  1N3T A;  4QPM A;  2KR1 A;  1GTP A;  1WM9 A;  4Q7J A;  3BMB A;  2LNZ A;  1FBX A;  1AIP C;  4R8Q A;  1WUR A;  2LO0 A;  1A8R A;  4JA3 A;  1WUQ A;  1EL6 A;  4DRB J;  4E45 B;  4DU6 A;  1N3R A;  1EFU B;  1N3S A;  4NE6 B;  5DMZ A;  3VEJ A;  1A9C A;  1IS7 A;  4DRA E;  2PN0 A;  1FB1 A;  1TFE A;  1WPL A;  4NE3 B;  4E44 B;  1IS8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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