4NE5B

Human mhf1-mhf2 complex
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 22
structure length 74
sequence length 74
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne5B02
4DRBJ 3B0BC 4E44B 4NE6B 4NE5B 4DRAE 4E45B 4NE3B
chains in the Genus database with same CATH superfamily
1A8RA 1N3TA 2P11A 2LO0A 2WSEG 2WSEK 3LW5G 4JA3A 2PN0A 3LW5K 4Q7JA 2WSCG 4E44B 1EFUB 1WPLA 2WSCK 4NE3B 1FBXA 1IS8A 1WURA 4DRBJ 1WUQA 2LNZA 2WSFG 4QPMA 3VEJA 1FB1A 3BMBA 1GTPA 1AIPC 2KR1A 1N3SA 2WSFK 4DU6A 2O01G 1N3RA 1EL6A 4R8QA 4NE6B 1WM9A 4E45B 1IS7A 1TFEA 3B0BC 5DMZA 4NE5B 4DRAE 1A9CA
chains in the Genus database with same CATH topology
1A8RA 1N3TA 2P11A 2LO0A 4JA3A 4Q7JA 2PN0A 4E44B 1EFUB 1WPLA 4NE3B 1FBXA 1IS8A 1WURA 4DRBJ 1WUQA 2LNZA 4QPMA 3VEJA 1FB1A 3BMBA 1GTPA 1AIPC 2KR1A 1N3SA 4DU6A 1N3RA 1EL6A 4R8QA 4NE6B 1WM9A 4E45B 1IS7A 1TFEA 3B0BC 5DMZA 4NE5B 4DRAE 1A9CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRB J;  3B0B C;  4E44 B;  4NE6 B;  4NE5 B;  4DRA E;  4E45 B;  4NE3 B; 
#chains in the Genus database with same CATH topology
 1A8R A;  1N3T A;  2P11 A;  2LO0 A;  2WSE G;  2WSE K;  3LW5 G;  4JA3 A;  2PN0 A;  3LW5 K;  4Q7J A;  2WSC G;  4E44 B;  1EFU B;  1WPL A;  2WSC K;  4NE3 B;  1FBX A;  1IS8 A;  1WUR A;  4DRB J;  1WUQ A;  2LNZ A;  2WSF G;  4QPM A;  3VEJ A;  1FB1 A;  3BMB A;  1GTP A;  1AIP C;  2KR1 A;  1N3S A;  2WSF K;  4DU6 A;  2O01 G;  1N3R A;  1EL6 A;  4R8Q A;  4NE6 B;  1WM9 A;  4E45 B;  1IS7 A;  1TFE A;  3B0B C;  5DMZ A;  4NE5 B;  4DRA E;  1A9C A; 
#chains in the Genus database with same CATH homology
 1A8R A;  1N3T A;  2P11 A;  2LO0 A;  4JA3 A;  4Q7J A;  2PN0 A;  4E44 B;  1EFU B;  1WPL A;  4NE3 B;  1FBX A;  1IS8 A;  1WUR A;  4DRB J;  1WUQ A;  2LNZ A;  4QPM A;  3VEJ A;  1FB1 A;  3BMB A;  1GTP A;  1AIP C;  2KR1 A;  1N3S A;  4DU6 A;  1N3R A;  1EL6 A;  4R8Q A;  4NE6 B;  1WM9 A;  4E45 B;  1IS7 A;  1TFE A;  3B0B C;  5DMZ A;  4NE5 B;  4DRA E;  1A9C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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