4NE5 | Genus

Total Genus 22

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	22
sequence length	74
structure length	74
Chain Sequence	SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 74 atoms

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74 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. pubmed doi rcsb
molecule keywords	Centromere protein S
molecule tags	Dna binding protein
source organism	Homo sapiens
total genus	22
structure length	74
sequence length	74
chains with identical sequence	D, F, H
ec nomenclature
pdb deposition date	2013-10-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF09415	CENP-X	CENP-S associating Centromere protein X

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.286.100	Mainly Alpha	Orthogonal Bundle	GTP Cyclohydrolase I; Chain A, domain 1	GTP Cyclohydrolase I; Chain A, domain 1	4ne5B02

3B0BC 4DRAE 4DRBJ 4E45B 4E44B 4NE6B 4NE5B 4NE3B
chains in the Genus database with same CATH superfamily

1A9CA 2PN0A 1AIPC 1IS8A 2WSEK 1N3SA 1WM9A 4NE3B 1EFUB 4DRBJ 2WSCG 1EL6A 1FBXA 4E44B 2LNZA 2WSFG 3BMBA 4NE6B 1N3TA 2KR1A 4R8QA 1WUQA 2P11A 2WSCK 4DRAE 3VEJA 4JA3A 2O01G 2WSFK 1IS7A 1WPLA 4QPMA 4DU6A 1WURA 4E45B 1TFEA 1GTPA 2LO0A 3LW5G 5DMZA 1N3RA 3B0BC 4Q7JA 3LW5K 2WSEG 1FB1A 4NE5B 1A8RA
chains in the Genus database with same CATH topology

1A9CA 2PN0A 1AIPC 1IS8A 1N3SA 1WM9A 4NE3B 1EFUB 4DRBJ 1EL6A 1FBXA 4E44B 2LNZA 3BMBA 4NE6B 1N3TA 2KR1A 4R8QA 1WUQA 2P11A 4DRAE 3VEJA 4JA3A 4E45B 4DU6A 1IS7A 1WPLA 4QPMA 1WURA 1TFEA 1GTPA 2LO0A 5DMZA 1N3RA 3B0BC 4Q7JA 1FB1A 4NE5B 1A8RA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3B0B C;  4DRA E;  4DRB J;  4E45 B;  4E44 B;  4NE6 B;  4NE5 B;  4NE3 B; 
#chains in the Genus database with same CATH topology
 1A9C A;  2PN0 A;  1AIP C;  1IS8 A;  2WSE K;  1N3S A;  1WM9 A;  4NE3 B;  1EFU B;  4DRB J;  2WSC G;  1EL6 A;  1FBX A;  4E44 B;  2LNZ A;  2WSF G;  3BMB A;  4NE6 B;  1N3T A;  2KR1 A;  4R8Q A;  1WUQ A;  2P11 A;  2WSC K;  4DRA E;  3VEJ A;  4JA3 A;  2O01 G;  2WSF K;  1IS7 A;  1WPL A;  4QPM A;  4DU6 A;  1WUR A;  4E45 B;  1TFE A;  1GTP A;  2LO0 A;  3LW5 G;  5DMZ A;  1N3R A;  3B0B C;  4Q7J A;  3LW5 K;  2WSE G;  1FB1 A;  4NE5 B;  1A8R A; 
#chains in the Genus database with same CATH homology
 1A9C A;  2PN0 A;  1AIP C;  1IS8 A;  1N3S A;  1WM9 A;  4NE3 B;  1EFU B;  4DRB J;  1EL6 A;  1FBX A;  4E44 B;  2LNZ A;  3BMB A;  4NE6 B;  1N3T A;  2KR1 A;  4R8Q A;  1WUQ A;  2P11 A;  4DRA E;  3VEJ A;  4JA3 A;  4E45 B;  4DU6 A;  1IS7 A;  1WPL A;  4QPM A;  1WUR A;  1TFE A;  1GTP A;  2LO0 A;  5DMZ A;  1N3R A;  3B0B C;  4Q7J A;  1FB1 A;  4NE5 B;  1A8R A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4NE5B

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations