4NE5B

Human mhf1-mhf2 complex
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Centromere protein S
total genus 22
structure length 74
sequence length 74
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne5B02
4DRAE 4NE5B 3B0BC 4E45B 4E44B 4NE6B 4DRBJ 4NE3B
chains in the Genus database with same CATH superfamily
1WM9A 1FBXA 1A9CA 1WUQA 1WURA 4E44B 3BMBA 4Q7JA 2KR1A 2WSEK 4NE3B 1EL6A 1N3TA 1N3RA 2LO0A 4E45B 4QPMA 1GTPA 2O01G 1A8RA 4R8QA 2LNZA 2PN0A 3B0BC 3LW5G 4JA3A 2WSFG 2WSCG 1IS7A 4NE6B 4DRBJ 3VEJA 1WPLA 1FB1A 4DRAE 4NE5B 1AIPC 1TFEA 1EFUB 2P11A 3LW5K 2WSEG 5DMZA 1IS8A 2WSFK 2WSCK 1N3SA 4DU6A
chains in the Genus database with same CATH topology
1WM9A 1FBXA 1A9CA 1WUQA 1WURA 4E44B 3BMBA 4Q7JA 2KR1A 4NE3B 1EL6A 1N3TA 1N3RA 2LO0A 4E45B 4QPMA 1GTPA 1A8RA 4R8QA 2LNZA 2PN0A 3B0BC 4JA3A 1IS7A 4NE6B 4DRBJ 3VEJA 1WPLA 1FB1A 4DRAE 4NE5B 1AIPC 1TFEA 1EFUB 2P11A 5DMZA 1IS8A 1N3SA 4DU6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRA E;  4NE5 B;  3B0B C;  4E45 B;  4E44 B;  4NE6 B;  4DRB J;  4NE3 B; 
#chains in the Genus database with same CATH topology
 1WM9 A;  1FBX A;  1A9C A;  1WUQ A;  1WUR A;  4E44 B;  3BMB A;  4Q7J A;  2KR1 A;  2WSE K;  4NE3 B;  1EL6 A;  1N3T A;  1N3R A;  2LO0 A;  4E45 B;  4QPM A;  1GTP A;  2O01 G;  1A8R A;  4R8Q A;  2LNZ A;  2PN0 A;  3B0B C;  3LW5 G;  4JA3 A;  2WSF G;  2WSC G;  1IS7 A;  4NE6 B;  4DRB J;  3VEJ A;  1WPL A;  1FB1 A;  4DRA E;  4NE5 B;  1AIP C;  1TFE A;  1EFU B;  2P11 A;  3LW5 K;  2WSE G;  5DMZ A;  1IS8 A;  2WSF K;  2WSC K;  1N3S A;  4DU6 A; 
#chains in the Genus database with same CATH homology
 1WM9 A;  1FBX A;  1A9C A;  1WUQ A;  1WUR A;  4E44 B;  3BMB A;  4Q7J A;  2KR1 A;  4NE3 B;  1EL6 A;  1N3T A;  1N3R A;  2LO0 A;  4E45 B;  4QPM A;  1GTP A;  1A8R A;  4R8Q A;  2LNZ A;  2PN0 A;  3B0B C;  4JA3 A;  1IS7 A;  4NE6 B;  4DRB J;  3VEJ A;  1WPL A;  1FB1 A;  4DRA E;  4NE5 B;  1AIP C;  1TFE A;  1EFU B;  2P11 A;  5DMZ A;  1IS8 A;  1N3S A;  4DU6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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