4NE5B

Human mhf1-mhf2 complex
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
source organism Homo sapiens
publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule keywords Centromere protein S
total genus 22
structure length 74
sequence length 74
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne5B02
3B0BC 4NE6B 4DRBJ 4E45B 4NE3B 4NE5B 4DRAE 4E44B
chains in the Genus database with same CATH superfamily
4JA3A 3VEJA 1FBXA 2LO0A 1IS7A 2WSCG 1WUQA 1WM9A 3LW5K 1GTPA 1N3TA 2P11A 4E44B 1AIPC 2WSEK 1FB1A 2WSFG 4Q7JA 1N3SA 1EL6A 1WPLA 4NE3B 4NE5B 1EFUB 3LW5G 4R8QA 2WSEG 3B0BC 1TFEA 4NE6B 1A8RA 2LNZA 5DMZA 4DRAE 2O01G 2PN0A 1A9CA 3BMBA 4QPMA 4DRBJ 4E45B 2WSCK 4DU6A 1N3RA 1WURA 1IS8A 2WSFK 2KR1A
chains in the Genus database with same CATH topology
4JA3A 3VEJA 1FBXA 2LO0A 1IS7A 1WUQA 1WM9A 1GTPA 1N3TA 2P11A 4E44B 1AIPC 1FB1A 4Q7JA 1N3SA 1EL6A 1WPLA 4NE3B 4NE5B 1EFUB 4R8QA 3B0BC 1TFEA 4NE6B 1A8RA 2LNZA 5DMZA 4DRAE 2PN0A 1A9CA 3BMBA 4QPMA 4DRBJ 4E45B 4DU6A 1N3RA 1WURA 1IS8A 2KR1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B0B C;  4NE6 B;  4DRB J;  4E45 B;  4NE3 B;  4NE5 B;  4DRA E;  4E44 B; 
#chains in the Genus database with same CATH topology
 4JA3 A;  3VEJ A;  1FBX A;  2LO0 A;  1IS7 A;  2WSC G;  1WUQ A;  1WM9 A;  3LW5 K;  1GTP A;  1N3T A;  2P11 A;  4E44 B;  1AIP C;  2WSE K;  1FB1 A;  2WSF G;  4Q7J A;  1N3S A;  1EL6 A;  1WPL A;  4NE3 B;  4NE5 B;  1EFU B;  3LW5 G;  4R8Q A;  2WSE G;  3B0B C;  1TFE A;  4NE6 B;  1A8R A;  2LNZ A;  5DMZ A;  4DRA E;  2O01 G;  2PN0 A;  1A9C A;  3BMB A;  4QPM A;  4DRB J;  4E45 B;  2WSC K;  4DU6 A;  1N3R A;  1WUR A;  1IS8 A;  2WSF K;  2KR1 A; 
#chains in the Genus database with same CATH homology
 4JA3 A;  3VEJ A;  1FBX A;  2LO0 A;  1IS7 A;  1WUQ A;  1WM9 A;  1GTP A;  1N3T A;  2P11 A;  4E44 B;  1AIP C;  1FB1 A;  4Q7J A;  1N3S A;  1EL6 A;  1WPL A;  4NE3 B;  4NE5 B;  1EFU B;  4R8Q A;  3B0B C;  1TFE A;  4NE6 B;  1A8R A;  2LNZ A;  5DMZ A;  4DRA E;  2PN0 A;  1A9C A;  3BMB A;  4QPM A;  4DRB J;  4E45 B;  4DU6 A;  1N3R A;  1WUR A;  1IS8 A;  2KR1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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