4NE6B

Human mhf1-mhf2 complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule keywords Centromere protein S
molecule tags Dna binding protein
source organism Homo sapiens
total genus 23
structure length 74
sequence length 74
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne6B02
4DRAE 4NE5B 4DRBJ 3B0BC 4E45B 4E44B 4NE3B 4NE6B
chains in the Genus database with same CATH superfamily
1EL6A 1WPLA 4JA3A 2LO0A 4DU6A 5DMZA 1AIPC 1FB1A 1IS7A 2PN0A 4QPMA 1N3TA 4DRBJ 4E44B 1GTPA 4NE6B 3BMBA 4DRAE 2O01G 1IS8A 3B0BC 1N3RA 2LNZA 4E45B 2WSFG 2P11A 2WSFK 2WSEG 2WSEK 4Q7JA 3VEJA 1WM9A 2WSCG 1TFEA 1FBXA 2WSCK 2KR1A 1A8RA 3LW5G 3LW5K 1A9CA 1N3SA 4NE5B 1EFUB 4R8QA 1WURA 4NE3B 1WUQA
chains in the Genus database with same CATH topology
1EL6A 1WPLA 4JA3A 2LO0A 4DU6A 5DMZA 1AIPC 1FB1A 1IS7A 2PN0A 4QPMA 1N3TA 4DRBJ 4E44B 1GTPA 4NE6B 3BMBA 4DRAE 1IS8A 3B0BC 1N3RA 2LNZA 4E45B 2P11A 4Q7JA 3VEJA 1WM9A 1TFEA 1FBXA 2KR1A 1A8RA 1A9CA 1N3SA 4NE5B 1EFUB 4R8QA 1WURA 4NE3B 1WUQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DRA E;  4NE5 B;  4DRB J;  3B0B C;  4E45 B;  4E44 B;  4NE3 B;  4NE6 B; 
#chains in the Genus database with same CATH topology
 1EL6 A;  1WPL A;  4JA3 A;  2LO0 A;  4DU6 A;  5DMZ A;  1AIP C;  1FB1 A;  1IS7 A;  2PN0 A;  4QPM A;  1N3T A;  4DRB J;  4E44 B;  1GTP A;  4NE6 B;  3BMB A;  4DRA E;  2O01 G;  1IS8 A;  3B0B C;  1N3R A;  2LNZ A;  4E45 B;  2WSF G;  2P11 A;  2WSF K;  2WSE G;  2WSE K;  4Q7J A;  3VEJ A;  1WM9 A;  2WSC G;  1TFE A;  1FBX A;  2WSC K;  2KR1 A;  1A8R A;  3LW5 G;  3LW5 K;  1A9C A;  1N3S A;  4NE5 B;  1EFU B;  4R8Q A;  1WUR A;  4NE3 B;  1WUQ A; 
#chains in the Genus database with same CATH homology
 1EL6 A;  1WPL A;  4JA3 A;  2LO0 A;  4DU6 A;  5DMZ A;  1AIP C;  1FB1 A;  1IS7 A;  2PN0 A;  4QPM A;  1N3T A;  4DRB J;  4E44 B;  1GTP A;  4NE6 B;  3BMB A;  4DRA E;  1IS8 A;  3B0B C;  1N3R A;  2LNZ A;  4E45 B;  2P11 A;  4Q7J A;  3VEJ A;  1WM9 A;  1TFE A;  1FBX A;  2KR1 A;  1A8R A;  1A9C A;  1N3S A;  4NE5 B;  1EFU B;  4R8Q A;  1WUR A;  4NE3 B;  1WUQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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