4NE6B

Human mhf1-mhf2 complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Centromere protein S
total genus 23
structure length 74
sequence length 74
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne6B02
4E44B 3B0BC 4DRAE 4NE3B 4DRBJ 4E45B 4NE6B 4NE5B
chains in the Genus database with same CATH superfamily
3VEJA 1GTPA 1A8RA 3B0BC 1EL6A 2WSCG 5DMZA 2WSEG 1AIPC 4NE6B 2WSFK 2O01G 1IS7A 1FBXA 1WUQA 2KR1A 1WPLA 4DRAE 4Q7JA 2LNZA 4QPMA 1FB1A 1WM9A 1N3RA 3BMBA 4E44B 1A9CA 1WURA 3LW5K 2LO0A 2WSFG 4JA3A 4DU6A 2P11A 4NE3B 4DRBJ 1N3TA 1EFUB 2WSEK 1IS8A 2WSCK 1TFEA 4R8QA 1N3SA 4E45B 2PN0A 4NE5B 3LW5G
chains in the Genus database with same CATH topology
3VEJA 1GTPA 1A8RA 3B0BC 1EL6A 5DMZA 1AIPC 4NE6B 1IS7A 1FBXA 1WUQA 2KR1A 1WPLA 4DRAE 4Q7JA 2LNZA 4QPMA 1FB1A 1WM9A 1N3RA 3BMBA 4E44B 1A9CA 1WURA 4JA3A 2LO0A 4DU6A 2P11A 4NE3B 4DRBJ 1N3TA 1EFUB 1IS8A 1TFEA 4R8QA 1N3SA 4E45B 2PN0A 4NE5B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E44 B;  3B0B C;  4DRA E;  4NE3 B;  4DRB J;  4E45 B;  4NE6 B;  4NE5 B; 
#chains in the Genus database with same CATH topology
 3VEJ A;  1GTP A;  1A8R A;  3B0B C;  1EL6 A;  2WSC G;  5DMZ A;  2WSE G;  1AIP C;  4NE6 B;  2WSF K;  2O01 G;  1IS7 A;  1FBX A;  1WUQ A;  2KR1 A;  1WPL A;  4DRA E;  4Q7J A;  2LNZ A;  4QPM A;  1FB1 A;  1WM9 A;  1N3R A;  3BMB A;  4E44 B;  1A9C A;  1WUR A;  3LW5 K;  2LO0 A;  2WSF G;  4JA3 A;  4DU6 A;  2P11 A;  4NE3 B;  4DRB J;  1N3T A;  1EFU B;  2WSE K;  1IS8 A;  2WSC K;  1TFE A;  4R8Q A;  1N3S A;  4E45 B;  2PN0 A;  4NE5 B;  3LW5 G; 
#chains in the Genus database with same CATH homology
 3VEJ A;  1GTP A;  1A8R A;  3B0B C;  1EL6 A;  5DMZ A;  1AIP C;  4NE6 B;  1IS7 A;  1FBX A;  1WUQ A;  2KR1 A;  1WPL A;  4DRA E;  4Q7J A;  2LNZ A;  4QPM A;  1FB1 A;  1WM9 A;  1N3R A;  3BMB A;  4E44 B;  1A9C A;  1WUR A;  4JA3 A;  2LO0 A;  4DU6 A;  2P11 A;  4NE3 B;  4DRB J;  1N3T A;  1EFU B;  1IS8 A;  1TFE A;  4R8Q A;  1N3S A;  4E45 B;  2PN0 A;  4NE5 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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