4NE6B

Human mhf1-mhf2 complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
source organism Homo sapiens
publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
molecule keywords Centromere protein S
total genus 23
structure length 74
sequence length 74
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne6B02
4NE5B 4E44B 4NE3B 4E45B 4DRBJ 4NE6B 4DRAE 3B0BC
chains in the Genus database with same CATH superfamily
1FB1A 2WSEG 1WURA 1FBXA 1EFUB 4DRBJ 2LNZA 2WSEK 2P11A 4Q7JA 4QPMA 2O01G 2KR1A 4NE3B 3BMBA 2WSCG 1TFEA 2WSCK 1GTPA 1WUQA 3B0BC 1EL6A 5DMZA 1N3TA 4NE5B 1WPLA 4E44B 1A8RA 1A9CA 4R8QA 4E45B 1WM9A 4NE6B 1AIPC 1IS8A 3LW5G 4JA3A 3LW5K 4DU6A 1N3SA 2LO0A 2WSFG 2PN0A 2WSFK 4DRAE 1N3RA 1IS7A 3VEJA
chains in the Genus database with same CATH topology
1FB1A 1WURA 1FBXA 1EFUB 4DRBJ 2LNZA 2P11A 4Q7JA 4QPMA 2KR1A 4NE3B 3BMBA 1TFEA 1GTPA 1WUQA 3B0BC 1EL6A 5DMZA 1N3TA 4NE5B 1WPLA 4E44B 1A8RA 1A9CA 4R8QA 4E45B 1WM9A 4NE6B 1AIPC 1IS8A 4JA3A 4DU6A 1N3SA 2LO0A 2PN0A 4DRAE 1N3RA 1IS7A 3VEJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE5 B;  4E44 B;  4NE3 B;  4E45 B;  4DRB J;  4NE6 B;  4DRA E;  3B0B C; 
#chains in the Genus database with same CATH topology
 1FB1 A;  2WSE G;  1WUR A;  1FBX A;  1EFU B;  4DRB J;  2LNZ A;  2WSE K;  2P11 A;  4Q7J A;  4QPM A;  2O01 G;  2KR1 A;  4NE3 B;  3BMB A;  2WSC G;  1TFE A;  2WSC K;  1GTP A;  1WUQ A;  3B0B C;  1EL6 A;  5DMZ A;  1N3T A;  4NE5 B;  1WPL A;  4E44 B;  1A8R A;  1A9C A;  4R8Q A;  4E45 B;  1WM9 A;  4NE6 B;  1AIP C;  1IS8 A;  3LW5 G;  4JA3 A;  3LW5 K;  4DU6 A;  1N3S A;  2LO0 A;  2WSF G;  2PN0 A;  2WSF K;  4DRA E;  1N3R A;  1IS7 A;  3VEJ A; 
#chains in the Genus database with same CATH homology
 1FB1 A;  1WUR A;  1FBX A;  1EFU B;  4DRB J;  2LNZ A;  2P11 A;  4Q7J A;  4QPM A;  2KR1 A;  4NE3 B;  3BMB A;  1TFE A;  1GTP A;  1WUQ A;  3B0B C;  1EL6 A;  5DMZ A;  1N3T A;  4NE5 B;  1WPL A;  4E44 B;  1A8R A;  1A9C A;  4R8Q A;  4E45 B;  1WM9 A;  4NE6 B;  1AIP C;  1IS8 A;  4JA3 A;  4DU6 A;  1N3S A;  2LO0 A;  2PN0 A;  4DRA E;  1N3R A;  1IS7 A;  3VEJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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