4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
molecule keywords Von Hippel-Lindau disease tumor suppressor
molecule tags Transcription
source organism Homo sapiens
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
3DQVC 4P5OA 3RTRA 4N9F3 4AP2B 4F52A 4APFB 3DPLC 4WQOD 1LDJA 1LDKB 2WZKA 1LDKA 4JGHD 4A64A 1U6GA 4EOZB 4HXIB
chains in the Genus database with same CATH superfamily
3DQVC 3RTRA 3CPZA 4NUUA 4AP2B 2PFVA 3CMLA 4P5OA 4NUVA 4N9F3 4WQOD 1LDJA 5F3JA 4A64A 1U6GA 3BQIA 2Y8DA 2WAUA 3RRCA 3DPLC 3BQLA 1LDKB 4JGHD 2WZKA 4HXIB 3BQKA 4YFSA 4F52A 4APFB 2B1EA 1LDKA 2XU0A 4EOZB
chains in the Genus database with same CATH topology
3DQVC 4P5OA 3RTRA 4N9F3 4AP2B 4F52A 4APFB 3DPLC 4WQOD 1LDJA 1LDKB 2WZKA 1LDKA 4JGHD 4A64A 1U6GA 4EOZB 4HXIB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DQV C;  4P5O A;  3RTR A;  4N9F 3;  4AP2 B;  4F52 A;  4APF B;  3DPL C;  4WQO D;  1LDJ A;  1LDK B;  2WZK A;  1LDK A;  4JGH D;  4A64 A;  1U6G A;  4EOZ B;  4HXI B; 
#chains in the Genus database with same CATH topology
 3DQV C;  3RTR A;  3CPZ A;  4NUU A;  4AP2 B;  2PFV A;  3CML A;  4P5O A;  4NUV A;  4N9F 3;  4WQO D;  1LDJ A;  5F3J A;  4A64 A;  1U6G A;  3BQI A;  2Y8D A;  2WAU A;  3RRC A;  3DPL C;  3BQL A;  1LDK B;  4JGH D;  2WZK A;  4HXI B;  3BQK A;  4YFS A;  4F52 A;  4APF B;  2B1E A;  1LDK A;  2XU0 A;  4EOZ B; 
#chains in the Genus database with same CATH homology
 3DQV C;  4P5O A;  3RTR A;  4N9F 3;  4AP2 B;  4F52 A;  4APF B;  3DPL C;  4WQO D;  1LDJ A;  1LDK B;  2WZK A;  1LDK A;  4JGH D;  4A64 A;  1U6G A;  4EOZ B;  4HXI B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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