4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
source organism Homo sapiens
publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
molecule keywords Von Hippel-Lindau disease tumor suppressor
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
1LDKB 4N9F3 4P5OA 4APFB 1LDKA 4AP2B 4F52A 3RTRA 1U6GA 4JGHD 4WQOD 4HXIB 1LDJA 3DPLC 4EOZB 4A64A 3DQVC 2WZKA
chains in the Genus database with same CATH superfamily
4N9F3 4APFB 1LDKA 2PFVA 3CPZA 3RTRA 4HXIB 2XU0A 2Y8DA 1LDKB 1U6GA 3CMLA 3RRCA 2WAUA 4YFSA 3BQIA 2B1EA 3DQVC 4AP2B 4F52A 4NUUA 5F3JA 4JGHD 4NUVA 3DPLC 3BQLA 4EOZB 3BQKA 4A64A 4P5OA 4WQOD 1LDJA 2WZKA
chains in the Genus database with same CATH topology
1LDKB 4N9F3 4P5OA 4APFB 1LDKA 4AP2B 4F52A 3RTRA 1U6GA 4JGHD 4WQOD 4HXIB 1LDJA 3DPLC 4EOZB 4A64A 3DQVC 2WZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LDK B;  4N9F 3;  4P5O A;  4APF B;  1LDK A;  4AP2 B;  4F52 A;  3RTR A;  1U6G A;  4JGH D;  4WQO D;  4HXI B;  1LDJ A;  3DPL C;  4EOZ B;  4A64 A;  3DQV C;  2WZK A; 
#chains in the Genus database with same CATH topology
 4N9F 3;  4APF B;  1LDK A;  2PFV A;  3CPZ A;  3RTR A;  4HXI B;  2XU0 A;  2Y8D A;  1LDK B;  1U6G A;  3CML A;  3RRC A;  2WAU A;  4YFS A;  3BQI A;  2B1E A;  3DQV C;  4AP2 B;  4F52 A;  4NUU A;  5F3J A;  4JGH D;  4NUV A;  3DPL C;  3BQL A;  4EOZ B;  3BQK A;  4A64 A;  4P5O A;  4WQO D;  1LDJ A;  2WZK A; 
#chains in the Genus database with same CATH homology
 1LDK B;  4N9F 3;  4P5O A;  4APF B;  1LDK A;  4AP2 B;  4F52 A;  3RTR A;  1U6G A;  4JGH D;  4WQO D;  4HXI B;  1LDJ A;  3DPL C;  4EOZ B;  4A64 A;  3DQV C;  2WZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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