4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
molecule keywords Von Hippel-Lindau disease tumor suppressor
molecule tags Transcription
source organism Homo sapiens
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
4JGHD 4APFB 3DPLC 1LDKB 4A64A 1LDJA 4EOZB 1LDKA 2WZKA 3DQVC 1U6GA 4WQOD 4P5OA 3RTRA 4AP2B 4HXIB 4F52A 4N9F3
chains in the Genus database with same CATH superfamily
3CPZA 4EOZB 3BQIA 1LDKA 4YFSA 3BQLA 4AP2B 4HXIB 4JGHD 2B1EA 3DPLC 1LDKB 3BQKA 1U6GA 4P5OA 4F52A 2PFVA 4NUUA 4A64A 1LDJA 3RRCA 2WZKA 3DQVC 2Y8DA 4APFB 3RTRA 3CMLA 4N9F3 2XU0A 2WAUA 4NUVA 5F3JA 4WQOD
chains in the Genus database with same CATH topology
4JGHD 4APFB 3DPLC 1LDKB 4A64A 1LDJA 4EOZB 1LDKA 2WZKA 3DQVC 1U6GA 4WQOD 4P5OA 3RTRA 4AP2B 4HXIB 4F52A 4N9F3
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JGH D;  4APF B;  3DPL C;  1LDK B;  4A64 A;  1LDJ A;  4EOZ B;  1LDK A;  2WZK A;  3DQV C;  1U6G A;  4WQO D;  4P5O A;  3RTR A;  4AP2 B;  4HXI B;  4F52 A;  4N9F 3; 
#chains in the Genus database with same CATH topology
 3CPZ A;  4EOZ B;  3BQI A;  1LDK A;  4YFS A;  3BQL A;  4AP2 B;  4HXI B;  4JGH D;  2B1E A;  3DPL C;  1LDK B;  3BQK A;  1U6G A;  4P5O A;  4F52 A;  2PFV A;  4NUU A;  4A64 A;  1LDJ A;  3RRC A;  2WZK A;  3DQV C;  2Y8D A;  4APF B;  3RTR A;  3CML A;  4N9F 3;  2XU0 A;  2WAU A;  4NUV A;  5F3J A;  4WQO D; 
#chains in the Genus database with same CATH homology
 4JGH D;  4APF B;  3DPL C;  1LDK B;  4A64 A;  1LDJ A;  4EOZ B;  1LDK A;  2WZK A;  3DQV C;  1U6G A;  4WQO D;  4P5O A;  3RTR A;  4AP2 B;  4HXI B;  4F52 A;  4N9F 3; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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