4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Von Hippel-Lindau disease tumor suppressor
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
4HXIB 4WQOD 4EOZB 1LDKB 4JGHD 2WZKA 1U6GA 4F52A 1LDJA 3DQVC 4AP2B 3RTRA 4A64A 4APFB 3DPLC 1LDKA 4N9F3 4P5OA
chains in the Genus database with same CATH superfamily
3RRCA 4WQOD 3CPZA 4F52A 4AP2B 4N9F3 3RTRA 4HXIB 2WAUA 2WZKA 1U6GA 3BQKA 3DQVC 3BQIA 4NUUA 4P5OA 2PFVA 4EOZB 3BQLA 4A64A 2B1EA 4APFB 1LDKA 3CMLA 5F3JA 1LDKB 4JGHD 1LDJA 4NUVA 2Y8DA 4YFSA 2XU0A 3DPLC
chains in the Genus database with same CATH topology
4HXIB 4WQOD 4EOZB 1LDKB 4JGHD 2WZKA 1U6GA 4F52A 1LDJA 3DQVC 4AP2B 3RTRA 4A64A 4APFB 3DPLC 1LDKA 4N9F3 4P5OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HXI B;  4WQO D;  4EOZ B;  1LDK B;  4JGH D;  2WZK A;  1U6G A;  4F52 A;  1LDJ A;  3DQV C;  4AP2 B;  3RTR A;  4A64 A;  4APF B;  3DPL C;  1LDK A;  4N9F 3;  4P5O A; 
#chains in the Genus database with same CATH topology
 3RRC A;  4WQO D;  3CPZ A;  4F52 A;  4AP2 B;  4N9F 3;  3RTR A;  4HXI B;  2WAU A;  2WZK A;  1U6G A;  3BQK A;  3DQV C;  3BQI A;  4NUU A;  4P5O A;  2PFV A;  4EOZ B;  3BQL A;  4A64 A;  2B1E A;  4APF B;  1LDK A;  3CML A;  5F3J A;  1LDK B;  4JGH D;  1LDJ A;  4NUV A;  2Y8D A;  4YFS A;  2XU0 A;  3DPL C; 
#chains in the Genus database with same CATH homology
 4HXI B;  4WQO D;  4EOZ B;  1LDK B;  4JGH D;  2WZK A;  1U6G A;  4F52 A;  1LDJ A;  3DQV C;  4AP2 B;  3RTR A;  4A64 A;  4APF B;  3DPL C;  1LDK A;  4N9F 3;  4P5O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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