4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Von Hippel-Lindau disease tumor suppressor
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
4P5OA 4HXIB 3DPLC 4APFB 4EOZB 4N9F3 3DQVC 1LDKB 3RTRA 1LDKA 4JGHD 4WQOD 1LDJA 4F52A 4AP2B 1U6GA 4A64A 2WZKA
chains in the Genus database with same CATH superfamily
4HXIB 2XU0A 2B1EA 1LDKB 3RRCA 4NUUA 1LDJA 4YFSA 3BQIA 3DPLC 3CPZA 1LDKA 3RTRA 3BQLA 4APFB 2Y8DA 4A64A 4P5OA 4EOZB 5F3JA 4N9F3 4JGHD 4WQOD 4AP2B 4F52A 2WZKA 3CMLA 2WAUA 3DQVC 4NUVA 2PFVA 3BQKA 1U6GA
chains in the Genus database with same CATH topology
4P5OA 4HXIB 3DPLC 4APFB 4EOZB 4N9F3 3DQVC 1LDKB 3RTRA 1LDKA 4JGHD 4WQOD 1LDJA 4F52A 4AP2B 1U6GA 4A64A 2WZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P5O A;  4HXI B;  3DPL C;  4APF B;  4EOZ B;  4N9F 3;  3DQV C;  1LDK B;  3RTR A;  1LDK A;  4JGH D;  4WQO D;  1LDJ A;  4F52 A;  4AP2 B;  1U6G A;  4A64 A;  2WZK A; 
#chains in the Genus database with same CATH topology
 4HXI B;  2XU0 A;  2B1E A;  1LDK B;  3RRC A;  4NUU A;  1LDJ A;  4YFS A;  3BQI A;  3DPL C;  3CPZ A;  1LDK A;  3RTR A;  3BQL A;  4APF B;  2Y8D A;  4A64 A;  4P5O A;  4EOZ B;  5F3J A;  4N9F 3;  4JGH D;  4WQO D;  4AP2 B;  4F52 A;  2WZK A;  3CML A;  2WAU A;  3DQV C;  4NUV A;  2PFV A;  3BQK A;  1U6G A; 
#chains in the Genus database with same CATH homology
 4P5O A;  4HXI B;  3DPL C;  4APF B;  4EOZ B;  4N9F 3;  3DQV C;  1LDK B;  3RTR A;  1LDK A;  4JGH D;  4WQO D;  1LDJ A;  4F52 A;  4AP2 B;  1U6G A;  4A64 A;  2WZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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