2DQBA

Crystal structure of dntp triphosphohydrolase from thermus thermophilus hb8, which is homologous to dgtp triphosphohydrolase
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
376
structure length
363
Chain Sequence
MRFSREALLELEASRLAPYAQKARDTRGRAHPEPESLYRTPYQKDRDRILHTTAFRRLEYKTQVLPGWAYYRTRLTHTLEVAQVSRSIARALGLNEDLTEAIALSHDLGHPPFGHTGEHVLNALMQDHGGFEHNAQALRILTHLEVRYPGFRGLNLTYEVLEGIATHEAGQGTLEAQVVDLSDAIAYAAHDLDDGFRAGLLHPEELKEVELLQALALEEGLDLLRLPELDRRVLVRQLLGYFITAAIEATHRRVEEAGVQSAEAVRRHPSRLAALGEEAEKALKALKAFLMERFYRHPEVLRERRKAEAVLEGLFAAYTRYPELLPREVQAKIPEEGLERAVCDYIAGMTDRFALEAYRRLSP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of dNTP-inducible dNTP triphosphohydrolase: insight into broad specificity for dNTPs and triphosphohydrolase-type hydrolysis
pubmed doi rcsb
molecule tags Hydrolase, dna binding protein
source organism Thermus thermophilus
molecule keywords Deoxyguanosinetriphosphate triphosphohydrolase, putative
total genus 132
structure length 363
sequence length 376
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.1.5.1: dGTPase.
pdb deposition date 2006-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01966 HD HD domain
A PF13286 HD_assoc Phosphohydrolase-associated domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3210.10 Mainly Alpha Orthogonal Bundle Hypothetical protein af1432 Hypothetical protein af1432 2dqbA00
4MLMA 1U6ZA 3TMDA 4TO0A 3HI0A 4QG0A 2GZ4A 4RXQA 1YOYA 1XX7A 1VJ7A 4ME4A 4MZ7A 3TMBA 2PAUA 4TNYA 3I7AA 5AO3A 4RXSA 4N71A 3CCGA 4BZCA 4N6WA 4Q7HA 4RXRA 4MDZA 4QFZA 3BG2A 4L7WA 4ZWGA 4L1JB 4QG2A 3NR1A 4TO6A 4XDSA 4R8ZA 2HEKA 5TKAA 4TO3A 5AO1A 3M1TA 4TO2A 5TK7A 1VQRA 2FLOA 4TNXA 3U1NA 4QFYA 3MEMA 3P3QA 4DMBA 3LJXA 4TO4A 3HC1A 5TK6A 2OGIA 3TMCA 2PAQA 4TNZA 5AO0A 4TNPA 3MZOA 4MLNA 3KH1A 2CQZA 2O6IA 1YNBA 4L7EA 5TK9A 4TNRA 5AO2A 4QG1A 2DQBA 4TO1A 4L1JA 2Q14A 3NQWA 4RXPA 5AO4A 4RXOA 4QFXA 4QG4A 2PQ7A 2PARA 4LRLA 5TK8A 2O08A 3IRHA 4TO5A 4MCWA 3TM8A 4X9EA 4TNQA 3RF0A 4ZWEA 2PGSA 4BZBA
chains in the Genus database with same CATH superfamily
4MLMA 1U6ZA 3TMDA 4TO0A 3HI0A 4QG0A 2GZ4A 4QQZA 4RXQA 1YOYA 1XX7A 1VJ7A 4ME4A 4MZ7A 3TMBA 2PAUA 4TNYA 3I7AA 5AO3A 4RXSA 4N71A 3CCGA 3S4LA 4BZCA 4N6WA 4Q7HA 4Q2CA 4RXRA 3SKDA 4MDZA 4QFZA 3BG2A 4L7WA 3GW7A 4ZWGA 4L1JB 4QG2A 3NR1A 4TO6A 4XDSA 4R8ZA 2HEKA 5TKAA 4QQXA 4TO3A 3M1TA 5AO1A 4TO2A 5TK7A 1VQRA 2FLOA 4TNXA 4QQYA 3U1NA 4QFYA 3MEMA 3P3QA 4QQWA 4DMBA 4Q2DA 3LJXA 4TO4A 3HC1A 5TK6A 2OGIA 3TMCA 2PAQA 4TNZA 5AO0A 4TNPA 3MZOA 4MLNA 3KH1A 2CQZA 3SK9A 2O6IA 1YNBA 4L7EA 3KQ5A 5TK9A 4TNRA 5AO2A 4QG1A 2DQBA 4TO1A 4L1JA 2Q14A 3NQWA 4RXPA 5AO4A 4RXOA 4QFXA 4QG4A 2PQ7A 2PARA 4LRLA 5TK8A 2O08A 3IRHA 4TO5A 4MCWA 3TM8A 4X9EA 4TNQA 3RF0A 4ZWEA 2PGSA 4BZBA
chains in the Genus database with same CATH topology
4MLMA 1U6ZA 3TMDA 4TO0A 3HI0A 4QG0A 2GZ4A 4QQZA 4RXQA 1YOYA 1XX7A 1VJ7A 4ME4A 4MZ7A 3TMBA 2PAUA 4TNYA 3I7AA 5AO3A 4RXSA 4N71A 3CCGA 3S4LA 4BZCA 4N6WA 4Q7HA 4Q2CA 4RXRA 3SKDA 4MDZA 4QFZA 3BG2A 4L7WA 3GW7A 4ZWGA 4L1JB 4QG2A 3NR1A 4TO6A 4XDSA 4R8ZA 2HEKA 5TKAA 4QQXA 4TO3A 3M1TA 5AO1A 4TO2A 5TK7A 1VQRA 2FLOA 4TNXA 4QQYA 3U1NA 4QFYA 3MEMA 3P3QA 4QQWA 4DMBA 4Q2DA 3LJXA 4TO4A 3HC1A 5TK6A 2OGIA 3TMCA 2PAQA 4TNZA 5AO0A 4TNPA 3MZOA 4MLNA 3KH1A 2CQZA 3SK9A 2O6IA 1YNBA 4L7EA 3KQ5A 5TK9A 4TNRA 5AO2A 4QG1A 2DQBA 4TO1A 4L1JA 2Q14A 3NQWA 4RXPA 5AO4A 4RXOA 4QFXA 4QG4A 2PQ7A 2PARA 4LRLA 5TK8A 2O08A 3IRHA 4TO5A 4MCWA 3TM8A 4X9EA 4TNQA 3RF0A 4ZWEA 2PGSA 4BZBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MLM A;  1U6Z A;  3TMD A;  4TO0 A;  3HI0 A;  4QG0 A;  2GZ4 A;  4RXQ A;  1YOY A;  1XX7 A;  1VJ7 A;  4ME4 A;  4MZ7 A;  3TMB A;  2PAU A;  4TNY A;  3I7A A;  5AO3 A;  4RXS A;  4N71 A;  3CCG A;  4BZC A;  4N6W A;  4Q7H A;  4RXR A;  4MDZ A;  4QFZ A;  3BG2 A;  4L7W A;  4ZWG A;  4L1J B;  4QG2 A;  3NR1 A;  4TO6 A;  4XDS A;  4R8Z A;  2HEK A;  5TKA A;  4TO3 A;  5AO1 A;  3M1T A;  4TO2 A;  5TK7 A;  1VQR A;  2FLO A;  4TNX A;  3U1N A;  4QFY A;  3MEM A;  3P3Q A;  4DMB A;  3LJX A;  4TO4 A;  3HC1 A;  5TK6 A;  2OGI A;  3TMC A;  2PAQ A;  4TNZ A;  5AO0 A;  4TNP A;  3MZO A;  4MLN A;  3KH1 A;  2CQZ A;  2O6I A;  1YNB A;  4L7E A;  5TK9 A;  4TNR A;  5AO2 A;  4QG1 A;  2DQB A;  4TO1 A;  4L1J A;  2Q14 A;  3NQW A;  4RXP A;  5AO4 A;  4RXO A;  4QFX A;  4QG4 A;  2PQ7 A;  2PAR A;  4LRL A;  5TK8 A;  2O08 A;  3IRH A;  4TO5 A;  4MCW A;  3TM8 A;  4X9E A;  4TNQ A;  3RF0 A;  4ZWE A;  2PGS A;  4BZB A; 
#chains in the Genus database with same CATH topology
 4MLM A;  1U6Z A;  3TMD A;  4TO0 A;  3HI0 A;  4QG0 A;  2GZ4 A;  4QQZ A;  4RXQ A;  1YOY A;  1XX7 A;  1VJ7 A;  4ME4 A;  4MZ7 A;  3TMB A;  2PAU A;  4TNY A;  3I7A A;  5AO3 A;  4RXS A;  4N71 A;  3CCG A;  3S4L A;  4BZC A;  4N6W A;  4Q7H A;  4Q2C A;  4RXR A;  3SKD A;  4MDZ A;  4QFZ A;  3BG2 A;  4L7W A;  3GW7 A;  4ZWG A;  4L1J B;  4QG2 A;  3NR1 A;  4TO6 A;  4XDS A;  4R8Z A;  2HEK A;  5TKA A;  4QQX A;  4TO3 A;  3M1T A;  5AO1 A;  4TO2 A;  5TK7 A;  1VQR A;  2FLO A;  4TNX A;  4QQY A;  3U1N A;  4QFY A;  3MEM A;  3P3Q A;  4QQW A;  4DMB A;  4Q2D A;  3LJX A;  4TO4 A;  3HC1 A;  5TK6 A;  2OGI A;  3TMC A;  2PAQ A;  4TNZ A;  5AO0 A;  4TNP A;  3MZO A;  4MLN A;  3KH1 A;  2CQZ A;  3SK9 A;  2O6I A;  1YNB A;  4L7E A;  3KQ5 A;  5TK9 A;  4TNR A;  5AO2 A;  4QG1 A;  2DQB A;  4TO1 A;  4L1J A;  2Q14 A;  3NQW A;  4RXP A;  5AO4 A;  4RXO A;  4QFX A;  4QG4 A;  2PQ7 A;  2PAR A;  4LRL A;  5TK8 A;  2O08 A;  3IRH A;  4TO5 A;  4MCW A;  3TM8 A;  4X9E A;  4TNQ A;  3RF0 A;  4ZWE A;  2PGS A;  4BZB A; 
#chains in the Genus database with same CATH homology
 4MLM A;  1U6Z A;  3TMD A;  4TO0 A;  3HI0 A;  4QG0 A;  2GZ4 A;  4QQZ A;  4RXQ A;  1YOY A;  1XX7 A;  1VJ7 A;  4ME4 A;  4MZ7 A;  3TMB A;  2PAU A;  4TNY A;  3I7A A;  5AO3 A;  4RXS A;  4N71 A;  3CCG A;  3S4L A;  4BZC A;  4N6W A;  4Q7H A;  4Q2C A;  4RXR A;  3SKD A;  4MDZ A;  4QFZ A;  3BG2 A;  4L7W A;  3GW7 A;  4ZWG A;  4L1J B;  4QG2 A;  3NR1 A;  4TO6 A;  4XDS A;  4R8Z A;  2HEK A;  5TKA A;  4QQX A;  4TO3 A;  3M1T A;  5AO1 A;  4TO2 A;  5TK7 A;  1VQR A;  2FLO A;  4TNX A;  4QQY A;  3U1N A;  4QFY A;  3MEM A;  3P3Q A;  4QQW A;  4DMB A;  4Q2D A;  3LJX A;  4TO4 A;  3HC1 A;  5TK6 A;  2OGI A;  3TMC A;  2PAQ A;  4TNZ A;  5AO0 A;  4TNP A;  3MZO A;  4MLN A;  3KH1 A;  2CQZ A;  3SK9 A;  2O6I A;  1YNB A;  4L7E A;  3KQ5 A;  5TK9 A;  4TNR A;  5AO2 A;  4QG1 A;  2DQB A;  4TO1 A;  4L1J A;  2Q14 A;  3NQW A;  4RXP A;  5AO4 A;  4RXO A;  4QFX A;  4QG4 A;  2PQ7 A;  2PAR A;  4LRL A;  5TK8 A;  2O08 A;  3IRH A;  4TO5 A;  4MCW A;  3TM8 A;  4X9E A;  4TNQ A;  3RF0 A;  4ZWE A;  2PGS A;  4BZB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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