2XHLB

Structure of a functional derivative of clostridium botulinum neurotoxin type b
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
415
structure length
410
Chain Sequence
NLQCIDVDNEDLFFIADKNSFSDDLSKNERIEYNTQSNYIENDFPINELILDTDLISKIELPSENTESLTDFNVDVPVYEKQPAIKKIFTDENTIFQYLYSQTFPLDIRDISLTSSFDDALLFSNKVYSFFSMDYIKTANKVVEAGLFAGWVKQIVNDFVIEANKSNTDISLIVPYIGLALNVGNETAKGNFENAFEIAGASILLEFIPELLIPVVGAFLLESYIDNKNKIIKTIDNALTKRNEKWSDMYGLIVAQWLSTVNTQFYTIKEGMYKALNYQAQALEEIIKYRYNIYSEKEKSNINIDFNDINSKLNEGINQAIDNINNFINGCSVSYLMKKMIPLAVEKLLDFDNTLKKNLLNYIDENKLYLIGSAEYEKSKVNKYLKTIMPFDLSIYTNDTILIEMFNKYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and Activity of a Functional Derivative of Clostridium Botulinum Neurotoxin B.
pubmed doi rcsb
molecule keywords BOTULINUM NEUROTOXIN B LIGHT CHAIN
molecule tags Hydrolase
source organism Clostridium botulinum
total genus 120
structure length 410
sequence length 415
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2010-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF07952 Toxin_trans Clostridium neurotoxin, Translocation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1120.10 Mainly Alpha Up-down Bundle Clostridium botulinum neurotoxin B, "coiled-coil" domain Clostridium botulinum neurotoxin b, "coiled-coil" domain 2xhlB00
4ZKTB 1F31A 1S0GA 2XHLB 1I1EA 3ZUQA 3V0BB 3V0AB 1S0CA 1G9DA 3ZURA 3VUOA 2W2DB 3ZUSA 1S0FA 2NYYA 1EPWA 1S0EA 5BQMB 5BQNA 1S0BA 2NP0A 3V0AA 3V0BA 1S0DA 1G9CA 1G9AA 3FFZA 1G9BA 2NZ9A 3BTAA
chains in the Genus database with same CATH superfamily
4ZKTB 1F31A 1S0GA 2XHLB 1I1EA 3ZUQA 3V0BB 3V0AB 1S0CA 1G9DA 3ZURA 3VUOA 2W2DB 3ZUSA 1S0FA 2NYYA 1EPWA 1S0EA 5BQMB 5BQNA 1S0BA 2NP0A 3V0AA 3V0BA 1S0DA 1G9CA 1G9AA 3FFZA 1G9BA 2NZ9A 3BTAA
chains in the Genus database with same CATH topology
4ZKTB 1F31A 1S0GA 2XHLB 1I1EA 3ZUQA 3V0BB 3V0AB 1S0CA 1G9DA 3ZURA 3VUOA 2W2DB 3ZUSA 1S0FA 2NYYA 1EPWA 1S0EA 5BQMB 5BQNA 1S0BA 2NP0A 3V0AA 3V0BA 1S0DA 1G9CA 1G9AA 3FFZA 1G9BA 2NZ9A 3BTAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZKT B;  1F31 A;  1S0G A;  2XHL B;  1I1E A;  3ZUQ A;  3V0B B;  3V0A B;  1S0C A;  1G9D A;  3ZUR A;  3VUO A;  2W2D B;  3ZUS A;  1S0F A;  2NYY A;  1EPW A;  1S0E A;  5BQM B;  5BQN A;  1S0B A;  2NP0 A;  3V0A A;  3V0B A;  1S0D A;  1G9C A;  1G9A A;  3FFZ A;  1G9B A;  2NZ9 A;  3BTA A; 
#chains in the Genus database with same CATH topology
 4ZKT B;  1F31 A;  1S0G A;  2XHL B;  1I1E A;  3ZUQ A;  3V0B B;  3V0A B;  1S0C A;  1G9D A;  3ZUR A;  3VUO A;  2W2D B;  3ZUS A;  1S0F A;  2NYY A;  1EPW A;  1S0E A;  5BQM B;  5BQN A;  1S0B A;  2NP0 A;  3V0A A;  3V0B A;  1S0D A;  1G9C A;  1G9A A;  3FFZ A;  1G9B A;  2NZ9 A;  3BTA A; 
#chains in the Genus database with same CATH homology
 4ZKT B;  1F31 A;  1S0G A;  2XHL B;  1I1E A;  3ZUQ A;  3V0B B;  3V0A B;  1S0C A;  1G9D A;  3ZUR A;  3VUO A;  2W2D B;  3ZUS A;  1S0F A;  2NYY A;  1EPW A;  1S0E A;  5BQM B;  5BQN A;  1S0B A;  2NP0 A;  3V0A A;  3V0B A;  1S0D A;  1G9C A;  1G9A A;  3FFZ A;  1G9B A;  2NZ9 A;  3BTA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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