2XHLB

Structure of a functional derivative of clostridium botulinum neurotoxin type b
Total Genus 120
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
415
structure length
410
Chain Sequence
NLQCIDVDNEDLFFIADKNSFSDDLSKNERIEYNTQSNYIENDFPINELILDTDLISKIELPSENTESLTDFNVDVPVYEKQPAIKKIFTDENTIFQYLYSQTFPLDIRDISLTSSFDDALLFSNKVYSFFSMDYIKTANKVVEAGLFAGWVKQIVNDFVIEANKSNTDISLIVPYIGLALNVGNETAKGNFENAFEIAGASILLEFIPELLIPVVGAFLLESYIDNKNKIIKTIDNALTKRNEKWSDMYGLIVAQWLSTVNTQFYTIKEGMYKALNYQAQALEEIIKYRYNIYSEKEKSNINIDFNDINSKLNEGINQAIDNINNFINGCSVSYLMKKMIPLAVEKLLDFDNTLKKNLLNYIDENKLYLIGSAEYEKSKVNKYLKTIMPFDLSIYTNDTILIEMFNKYN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Clostridium botulinum
publication title Structure and Activity of a Functional Derivative of Clostridium Botulinum Neurotoxin B.
pubmed doi rcsb
molecule keywords BOTULINUM NEUROTOXIN B LIGHT CHAIN
total genus 120
structure length 410
sequence length 415
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2010-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF07952 Toxin_trans Clostridium neurotoxin, Translocation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1120.10 Mainly Alpha Up-down Bundle Clostridium botulinum neurotoxin B, "coiled-coil" domain Clostridium botulinum neurotoxin b, "coiled-coil" domain 2xhlB00
2NZ9A 3V0AA 3FFZA 1S0BA 3VUOA 1S0CA 1S0FA 4ZKTB 1G9CA 3ZUQA 2XHLB 5BQNA 3ZUSA 1S0DA 5BQMB 3V0BA 1I1EA 2NYYA 3V0AB 1S0EA 3ZURA 1G9DA 1G9BA 1G9AA 1EPWA 3V0BB 1F31A 1S0GA 2W2DB 3BTAA 2NP0A
chains in the Genus database with same CATH superfamily
2NZ9A 3V0AA 3FFZA 1S0BA 3VUOA 1S0CA 1S0FA 4ZKTB 1G9CA 3ZUQA 2XHLB 5BQNA 3ZUSA 1S0DA 5BQMB 3V0BA 1I1EA 2NYYA 3V0AB 1S0EA 3ZURA 1G9DA 1G9BA 1G9AA 1EPWA 3V0BB 1F31A 1S0GA 2W2DB 3BTAA 2NP0A
chains in the Genus database with same CATH topology
2NZ9A 3V0AA 3FFZA 1S0BA 3VUOA 1S0CA 1S0FA 4ZKTB 1G9CA 3ZUQA 2XHLB 5BQNA 3ZUSA 1S0DA 5BQMB 3V0BA 1I1EA 2NYYA 3V0AB 1S0EA 3ZURA 1G9DA 1G9BA 1G9AA 1EPWA 3V0BB 1F31A 1S0GA 2W2DB 3BTAA 2NP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NZ9 A;  3V0A A;  3FFZ A;  1S0B A;  3VUO A;  1S0C A;  1S0F A;  4ZKT B;  1G9C A;  3ZUQ A;  2XHL B;  5BQN A;  3ZUS A;  1S0D A;  5BQM B;  3V0B A;  1I1E A;  2NYY A;  3V0A B;  1S0E A;  3ZUR A;  1G9D A;  1G9B A;  1G9A A;  1EPW A;  3V0B B;  1F31 A;  1S0G A;  2W2D B;  3BTA A;  2NP0 A; 
#chains in the Genus database with same CATH topology
 2NZ9 A;  3V0A A;  3FFZ A;  1S0B A;  3VUO A;  1S0C A;  1S0F A;  4ZKT B;  1G9C A;  3ZUQ A;  2XHL B;  5BQN A;  3ZUS A;  1S0D A;  5BQM B;  3V0B A;  1I1E A;  2NYY A;  3V0A B;  1S0E A;  3ZUR A;  1G9D A;  1G9B A;  1G9A A;  1EPW A;  3V0B B;  1F31 A;  1S0G A;  2W2D B;  3BTA A;  2NP0 A; 
#chains in the Genus database with same CATH homology
 2NZ9 A;  3V0A A;  3FFZ A;  1S0B A;  3VUO A;  1S0C A;  1S0F A;  4ZKT B;  1G9C A;  3ZUQ A;  2XHL B;  5BQN A;  3ZUS A;  1S0D A;  5BQM B;  3V0B A;  1I1E A;  2NYY A;  3V0A B;  1S0E A;  3ZUR A;  1G9D A;  1G9B A;  1G9A A;  1EPW A;  3V0B B;  1F31 A;  1S0G A;  2W2D B;  3BTA A;  2NP0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...