2XHLB

Structure of a functional derivative of clostridium botulinum neurotoxin type b
Total Genus 120
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
415
structure length
410
Chain Sequence
NLQCIDVDNEDLFFIADKNSFSDDLSKNERIEYNTQSNYIENDFPINELILDTDLISKIELPSENTESLTDFNVDVPVYEKQPAIKKIFTDENTIFQYLYSQTFPLDIRDISLTSSFDDALLFSNKVYSFFSMDYIKTANKVVEAGLFAGWVKQIVNDFVIEANKSNTDISLIVPYIGLALNVGNETAKGNFENAFEIAGASILLEFIPELLIPVVGAFLLESYIDNKNKIIKTIDNALTKRNEKWSDMYGLIVAQWLSTVNTQFYTIKEGMYKALNYQAQALEEIIKYRYNIYSEKEKSNINIDFNDINSKLNEGINQAIDNINNFINGCSVSYLMKKMIPLAVEKLLDFDNTLKKNLLNYIDENKLYLIGSAEYEKSKVNKYLKTIMPFDLSIYTNDTILIEMFNKYN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords BOTULINUM NEUROTOXIN B LIGHT CHAIN
publication title Structure and Activity of a Functional Derivative of Clostridium Botulinum Neurotoxin B.
pubmed doi rcsb
source organism Clostridium botulinum
total genus 120
structure length 410
sequence length 415
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2010-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF07952 Toxin_trans Clostridium neurotoxin, Translocation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1120.10 Mainly Alpha Up-down Bundle Clostridium botulinum neurotoxin B, "coiled-coil" domain Clostridium botulinum neurotoxin b, "coiled-coil" domain 2xhlB00
3V0AB 3V0BB 4ZKTB 1S0FA 5BQNA 3ZUSA 1F31A 1G9CA 3ZURA 3VUOA 2W2DB 1S0BA 3V0AA 3V0BA 3FFZA 2NYYA 1G9AA 2NP0A 3BTAA 1G9BA 3ZUQA 1S0DA 1S0CA 1S0EA 1S0GA 2XHLB 1I1EA 2NZ9A 5BQMB 1G9DA 1EPWA
chains in the Genus database with same CATH superfamily
3V0AB 3V0BB 4ZKTB 1S0FA 5BQNA 3ZUSA 1F31A 1G9CA 3ZURA 3VUOA 2W2DB 1S0BA 3V0AA 3V0BA 3FFZA 2NYYA 1G9AA 2NP0A 3BTAA 1G9BA 3ZUQA 1S0DA 1S0CA 1S0EA 1S0GA 2XHLB 1I1EA 2NZ9A 5BQMB 1G9DA 1EPWA
chains in the Genus database with same CATH topology
3V0AB 3V0BB 4ZKTB 1S0FA 5BQNA 3ZUSA 1F31A 1G9CA 3ZURA 3VUOA 2W2DB 1S0BA 3V0AA 3V0BA 3FFZA 2NYYA 1G9AA 2NP0A 3BTAA 1G9BA 3ZUQA 1S0DA 1S0CA 1S0EA 1S0GA 2XHLB 1I1EA 2NZ9A 5BQMB 1G9DA 1EPWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V0A B;  3V0B B;  4ZKT B;  1S0F A;  5BQN A;  3ZUS A;  1F31 A;  1G9C A;  3ZUR A;  3VUO A;  2W2D B;  1S0B A;  3V0A A;  3V0B A;  3FFZ A;  2NYY A;  1G9A A;  2NP0 A;  3BTA A;  1G9B A;  3ZUQ A;  1S0D A;  1S0C A;  1S0E A;  1S0G A;  2XHL B;  1I1E A;  2NZ9 A;  5BQM B;  1G9D A;  1EPW A; 
#chains in the Genus database with same CATH topology
 3V0A B;  3V0B B;  4ZKT B;  1S0F A;  5BQN A;  3ZUS A;  1F31 A;  1G9C A;  3ZUR A;  3VUO A;  2W2D B;  1S0B A;  3V0A A;  3V0B A;  3FFZ A;  2NYY A;  1G9A A;  2NP0 A;  3BTA A;  1G9B A;  3ZUQ A;  1S0D A;  1S0C A;  1S0E A;  1S0G A;  2XHL B;  1I1E A;  2NZ9 A;  5BQM B;  1G9D A;  1EPW A; 
#chains in the Genus database with same CATH homology
 3V0A B;  3V0B B;  4ZKT B;  1S0F A;  5BQN A;  3ZUS A;  1F31 A;  1G9C A;  3ZUR A;  3VUO A;  2W2D B;  1S0B A;  3V0A A;  3V0B A;  3FFZ A;  2NYY A;  1G9A A;  2NP0 A;  3BTA A;  1G9B A;  3ZUQ A;  1S0D A;  1S0C A;  1S0E A;  1S0G A;  2XHL B;  1I1E A;  2NZ9 A;  5BQM B;  1G9D A;  1EPW A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...