2XHLB

Structure of a functional derivative of clostridium botulinum neurotoxin type b
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
415
structure length
410
Chain Sequence
NLQCIDVDNEDLFFIADKNSFSDDLSKNERIEYNTQSNYIENDFPINELILDTDLISKIELPSENTESLTDFNVDVPVYEKQPAIKKIFTDENTIFQYLYSQTFPLDIRDISLTSSFDDALLFSNKVYSFFSMDYIKTANKVVEAGLFAGWVKQIVNDFVIEANKSNTDISLIVPYIGLALNVGNETAKGNFENAFEIAGASILLEFIPELLIPVVGAFLLESYIDNKNKIIKTIDNALTKRNEKWSDMYGLIVAQWLSTVNTQFYTIKEGMYKALNYQAQALEEIIKYRYNIYSEKEKSNINIDFNDINSKLNEGINQAIDNINNFINGCSVSYLMKKMIPLAVEKLLDFDNTLKKNLLNYIDENKLYLIGSAEYEKSKVNKYLKTIMPFDLSIYTNDTILIEMFNKYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and Activity of a Functional Derivative of Clostridium Botulinum Neurotoxin B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords BOTULINUM NEUROTOXIN B LIGHT CHAIN
total genus 120
structure length 410
sequence length 415
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2010-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF07952 Toxin_trans Clostridium neurotoxin, Translocation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1120.10 Mainly Alpha Up-down Bundle Clostridium botulinum neurotoxin B, "coiled-coil" domain Clostridium botulinum neurotoxin b, "coiled-coil" domain 2xhlB00
1S0GA 2NZ9A 3ZUSA 2NP0A 5BQMB 3ZUQA 2W2DB 3VUOA 1S0CA 3V0AB 3V0AA 1S0BA 5BQNA 2NYYA 1S0DA 2XHLB 1F31A 1G9BA 1G9CA 3BTAA 1S0FA 4ZKTB 1G9AA 1EPWA 1I1EA 1S0EA 1G9DA 3V0BB 3FFZA 3V0BA 3ZURA
chains in the Genus database with same CATH superfamily
1S0GA 2NZ9A 3ZUSA 2NP0A 5BQMB 3ZUQA 2W2DB 3VUOA 1S0CA 3V0AB 3V0AA 1S0BA 5BQNA 2NYYA 1S0DA 2XHLB 1F31A 1G9BA 1G9CA 3BTAA 1S0FA 4ZKTB 1G9AA 1EPWA 1I1EA 1S0EA 1G9DA 3V0BB 3FFZA 3V0BA 3ZURA
chains in the Genus database with same CATH topology
1S0GA 2NZ9A 3ZUSA 2NP0A 5BQMB 3ZUQA 2W2DB 3VUOA 1S0CA 3V0AB 3V0AA 1S0BA 5BQNA 2NYYA 1S0DA 2XHLB 1F31A 1G9BA 1G9CA 3BTAA 1S0FA 4ZKTB 1G9AA 1EPWA 1I1EA 1S0EA 1G9DA 3V0BB 3FFZA 3V0BA 3ZURA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S0G A;  2NZ9 A;  3ZUS A;  2NP0 A;  5BQM B;  3ZUQ A;  2W2D B;  3VUO A;  1S0C A;  3V0A B;  3V0A A;  1S0B A;  5BQN A;  2NYY A;  1S0D A;  2XHL B;  1F31 A;  1G9B A;  1G9C A;  3BTA A;  1S0F A;  4ZKT B;  1G9A A;  1EPW A;  1I1E A;  1S0E A;  1G9D A;  3V0B B;  3FFZ A;  3V0B A;  3ZUR A; 
#chains in the Genus database with same CATH topology
 1S0G A;  2NZ9 A;  3ZUS A;  2NP0 A;  5BQM B;  3ZUQ A;  2W2D B;  3VUO A;  1S0C A;  3V0A B;  3V0A A;  1S0B A;  5BQN A;  2NYY A;  1S0D A;  2XHL B;  1F31 A;  1G9B A;  1G9C A;  3BTA A;  1S0F A;  4ZKT B;  1G9A A;  1EPW A;  1I1E A;  1S0E A;  1G9D A;  3V0B B;  3FFZ A;  3V0B A;  3ZUR A; 
#chains in the Genus database with same CATH homology
 1S0G A;  2NZ9 A;  3ZUS A;  2NP0 A;  5BQM B;  3ZUQ A;  2W2D B;  3VUO A;  1S0C A;  3V0A B;  3V0A A;  1S0B A;  5BQN A;  2NYY A;  1S0D A;  2XHL B;  1F31 A;  1G9B A;  1G9C A;  3BTA A;  1S0F A;  4ZKT B;  1G9A A;  1EPW A;  1I1E A;  1S0E A;  1G9D A;  3V0B B;  3FFZ A;  3V0B A;  3ZUR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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