4L7EA

Three dimensional structure of mutant d78a of human hd domain-containing protein 2, genomics consortium (nesg) target hr6723
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
187
structure length
187
Chain Sequence
HGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVHAMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWEEYETQSSAEAKFVKQLDQCEMILQASEYEDLEHKPGRLQDFYDSTAGKFNHPEIVQLVSELEAERSTNIAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Northeast Structural Genomics Consortium Target HR6723
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords HD domain-containing protein 2
total genus 70
structure length 187
sequence length 187
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13023 HD_3 HD domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3210.10 Mainly Alpha Orthogonal Bundle Hypothetical protein af1432 Hypothetical protein af1432 4l7eA00
3KH1A 3NQWA 4TO3A 2PARA 1XX7A 4XDSA 3P3QA 5TKAA 4LRLA 3TMDA 2PAUA 3HC1A 5AO4A 4N6WA 5AO2A 3BG2A 2GZ4A 1YNBA 4ME4A 4RXSA 4QG4A 4TNXA 1VJ7A 4X9EA 4BZBA 4DMBA 4ZWGA 3IRHA 1U6ZA 4TO1A 4MLMA 4L1JA 2O08A 3TMCA 3HI0A 4RXOA 4TO5A 4L7WA 4MZ7A 5TK9A 3U1NA 2PGSA 4QFYA 2PQ7A 4TO6A 4TNZA 5TK6A 4TO2A 4TNRA 4RXRA 5AO1A 4QFXA 3M1TA 2FLOA 2HEKA 4TNQA 4TO0A 4RXPA 5AO3A 3RF0A 5AO0A 3TM8A 4L1JB 5TK8A 3I7AA 2CQZA 2PAQA 2Q14A 4L7EA 3LJXA 3MZOA 3MEMA 3TMBA 4R8ZA 4TNYA 4TNPA 4QG1A 4N71A 1YOYA 4QFZA 3CCGA 3NR1A 4QG2A 4MCWA 4QG0A 5TK7A 2O6IA 2OGIA 2DQBA 4Q7HA 4MLNA 4BZCA 4MDZA 4RXQA 1VQRA 4ZWEA 4TO4A
chains in the Genus database with same CATH superfamily
3KH1A 3NQWA 4TO3A 2PARA 1XX7A 4XDSA 3P3QA 5TKAA 4LRLA 4QQXA 3TMDA 2PAUA 3HC1A 5AO4A 4N6WA 5AO2A 3SK9A 3BG2A 2GZ4A 1YNBA 4ME4A 4RXSA 4QG4A 4TNXA 1VJ7A 4Q2CA 4X9EA 4BZBA 4DMBA 4ZWGA 3IRHA 1U6ZA 4TO1A 4MLMA 3S4LA 4L1JA 2O08A 3TMCA 3HI0A 4RXOA 3SKDA 4TO5A 4L7WA 4MZ7A 5TK9A 3U1NA 2PGSA 4QFYA 4Q2DA 2PQ7A 4TO6A 4TNZA 5TK6A 4TO2A 4TNRA 4RXRA 5AO1A 4QFXA 4QQWA 3M1TA 2FLOA 2HEKA 4TNQA 4TO0A 4RXPA 5AO3A 3RF0A 5AO0A 3TM8A 4L1JB 5TK8A 3I7AA 2CQZA 2PAQA 2Q14A 4L7EA 3LJXA 4QQZA 3MZOA 3KQ5A 3MEMA 3TMBA 4R8ZA 4QQYA 4TNYA 4TNPA 4QG1A 4N71A 1YOYA 4QFZA 3CCGA 3GW7A 3NR1A 4QG2A 4MCWA 4QG0A 5TK7A 2O6IA 2OGIA 2DQBA 4Q7HA 4MLNA 4BZCA 4MDZA 4RXQA 1VQRA 4ZWEA 4TO4A
chains in the Genus database with same CATH topology
3KH1A 3NQWA 4TO3A 2PARA 1XX7A 4XDSA 3P3QA 5TKAA 4LRLA 4QQXA 3TMDA 2PAUA 3HC1A 5AO4A 4N6WA 5AO2A 3SK9A 3BG2A 2GZ4A 1YNBA 4ME4A 4RXSA 4QG4A 4TNXA 1VJ7A 4Q2CA 4X9EA 4BZBA 4DMBA 4ZWGA 3IRHA 1U6ZA 4TO1A 4MLMA 3S4LA 4L1JA 2O08A 3TMCA 3HI0A 4RXOA 3SKDA 4TO5A 4L7WA 4MZ7A 5TK9A 3U1NA 2PGSA 4QFYA 4Q2DA 2PQ7A 4TO6A 4TNZA 5TK6A 4TO2A 4TNRA 4RXRA 5AO1A 4QFXA 4QQWA 3M1TA 2FLOA 2HEKA 4TNQA 4TO0A 4RXPA 5AO3A 3RF0A 5AO0A 3TM8A 4L1JB 5TK8A 3I7AA 2CQZA 2PAQA 2Q14A 4L7EA 3LJXA 4QQZA 3MZOA 3KQ5A 3MEMA 3TMBA 4R8ZA 4QQYA 4TNYA 4TNPA 4QG1A 4N71A 1YOYA 4QFZA 3CCGA 3GW7A 3NR1A 4QG2A 4MCWA 4QG0A 5TK7A 2O6IA 2OGIA 2DQBA 4Q7HA 4MLNA 4BZCA 4MDZA 4RXQA 1VQRA 4ZWEA 4TO4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KH1 A;  3NQW A;  4TO3 A;  2PAR A;  1XX7 A;  4XDS A;  3P3Q A;  5TKA A;  4LRL A;  3TMD A;  2PAU A;  3HC1 A;  5AO4 A;  4N6W A;  5AO2 A;  3BG2 A;  2GZ4 A;  1YNB A;  4ME4 A;  4RXS A;  4QG4 A;  4TNX A;  1VJ7 A;  4X9E A;  4BZB A;  4DMB A;  4ZWG A;  3IRH A;  1U6Z A;  4TO1 A;  4MLM A;  4L1J A;  2O08 A;  3TMC A;  3HI0 A;  4RXO A;  4TO5 A;  4L7W A;  4MZ7 A;  5TK9 A;  3U1N A;  2PGS A;  4QFY A;  2PQ7 A;  4TO6 A;  4TNZ A;  5TK6 A;  4TO2 A;  4TNR A;  4RXR A;  5AO1 A;  4QFX A;  3M1T A;  2FLO A;  2HEK A;  4TNQ A;  4TO0 A;  4RXP A;  5AO3 A;  3RF0 A;  5AO0 A;  3TM8 A;  4L1J B;  5TK8 A;  3I7A A;  2CQZ A;  2PAQ A;  2Q14 A;  4L7E A;  3LJX A;  3MZO A;  3MEM A;  3TMB A;  4R8Z A;  4TNY A;  4TNP A;  4QG1 A;  4N71 A;  1YOY A;  4QFZ A;  3CCG A;  3NR1 A;  4QG2 A;  4MCW A;  4QG0 A;  5TK7 A;  2O6I A;  2OGI A;  2DQB A;  4Q7H A;  4MLN A;  4BZC A;  4MDZ A;  4RXQ A;  1VQR A;  4ZWE A;  4TO4 A; 
#chains in the Genus database with same CATH topology
 3KH1 A;  3NQW A;  4TO3 A;  2PAR A;  1XX7 A;  4XDS A;  3P3Q A;  5TKA A;  4LRL A;  4QQX A;  3TMD A;  2PAU A;  3HC1 A;  5AO4 A;  4N6W A;  5AO2 A;  3SK9 A;  3BG2 A;  2GZ4 A;  1YNB A;  4ME4 A;  4RXS A;  4QG4 A;  4TNX A;  1VJ7 A;  4Q2C A;  4X9E A;  4BZB A;  4DMB A;  4ZWG A;  3IRH A;  1U6Z A;  4TO1 A;  4MLM A;  3S4L A;  4L1J A;  2O08 A;  3TMC A;  3HI0 A;  4RXO A;  3SKD A;  4TO5 A;  4L7W A;  4MZ7 A;  5TK9 A;  3U1N A;  2PGS A;  4QFY A;  4Q2D A;  2PQ7 A;  4TO6 A;  4TNZ A;  5TK6 A;  4TO2 A;  4TNR A;  4RXR A;  5AO1 A;  4QFX A;  4QQW A;  3M1T A;  2FLO A;  2HEK A;  4TNQ A;  4TO0 A;  4RXP A;  5AO3 A;  3RF0 A;  5AO0 A;  3TM8 A;  4L1J B;  5TK8 A;  3I7A A;  2CQZ A;  2PAQ A;  2Q14 A;  4L7E A;  3LJX A;  4QQZ A;  3MZO A;  3KQ5 A;  3MEM A;  3TMB A;  4R8Z A;  4QQY A;  4TNY A;  4TNP A;  4QG1 A;  4N71 A;  1YOY A;  4QFZ A;  3CCG A;  3GW7 A;  3NR1 A;  4QG2 A;  4MCW A;  4QG0 A;  5TK7 A;  2O6I A;  2OGI A;  2DQB A;  4Q7H A;  4MLN A;  4BZC A;  4MDZ A;  4RXQ A;  1VQR A;  4ZWE A;  4TO4 A; 
#chains in the Genus database with same CATH homology
 3KH1 A;  3NQW A;  4TO3 A;  2PAR A;  1XX7 A;  4XDS A;  3P3Q A;  5TKA A;  4LRL A;  4QQX A;  3TMD A;  2PAU A;  3HC1 A;  5AO4 A;  4N6W A;  5AO2 A;  3SK9 A;  3BG2 A;  2GZ4 A;  1YNB A;  4ME4 A;  4RXS A;  4QG4 A;  4TNX A;  1VJ7 A;  4Q2C A;  4X9E A;  4BZB A;  4DMB A;  4ZWG A;  3IRH A;  1U6Z A;  4TO1 A;  4MLM A;  3S4L A;  4L1J A;  2O08 A;  3TMC A;  3HI0 A;  4RXO A;  3SKD A;  4TO5 A;  4L7W A;  4MZ7 A;  5TK9 A;  3U1N A;  2PGS A;  4QFY A;  4Q2D A;  2PQ7 A;  4TO6 A;  4TNZ A;  5TK6 A;  4TO2 A;  4TNR A;  4RXR A;  5AO1 A;  4QFX A;  4QQW A;  3M1T A;  2FLO A;  2HEK A;  4TNQ A;  4TO0 A;  4RXP A;  5AO3 A;  3RF0 A;  5AO0 A;  3TM8 A;  4L1J B;  5TK8 A;  3I7A A;  2CQZ A;  2PAQ A;  2Q14 A;  4L7E A;  3LJX A;  4QQZ A;  3MZO A;  3KQ5 A;  3MEM A;  3TMB A;  4R8Z A;  4QQY A;  4TNY A;  4TNP A;  4QG1 A;  4N71 A;  1YOY A;  4QFZ A;  3CCG A;  3GW7 A;  3NR1 A;  4QG2 A;  4MCW A;  4QG0 A;  5TK7 A;  2O6I A;  2OGI A;  2DQB A;  4Q7H A;  4MLN A;  4BZC A;  4MDZ A;  4RXQ A;  1VQR A;  4ZWE A;  4TO4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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