4L7WA

Crystal structure mutant h77a of human hd domain-containing protein 2, genomics consortium (nesg) target hr6723
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
188
structure length
188
Chain Sequence
GARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVADMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWEEYETQSSAEAKFVKQLDQCEMILQASEYEDLEHKPGRLQDFYDSTAGKFNHPEIVQLVSELEAERSTNIAAAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Northeast Structural Genomics Consortium Target HR6723
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords HD domain-containing protein 2
total genus 69
structure length 188
sequence length 188
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13023 HD_3 HD domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3210.10 Mainly Alpha Orthogonal Bundle Hypothetical protein af1432 Hypothetical protein af1432 4l7wA00
4MZ7A 3BG2A 3U1NA 2OGIA 5AO0A 5AO4A 4BZCA 5AO3A 3IRHA 4RXSA 4TO0A 4QG4A 4QG0A 4TNPA 2PGSA 5AO2A 5TK8A 4BZBA 3KH1A 5TK7A 2O08A 3TMBA 4TO5A 5AO1A 2PQ7A 2HEKA 4TO3A 2PAUA 4QG2A 4TNQA 4N6WA 4N71A 3LJXA 1U6ZA 4MLNA 4L7EA 3I7AA 5TKAA 4TNXA 2DQBA 3MEMA 4TO6A 4Q7HA 3NQWA 4MCWA 4L7WA 4RXQA 3RF0A 1VQRA 4X9EA 4TNYA 4QFXA 4TO2A 4LRLA 3HC1A 5TK9A 2PARA 2FLOA 4TNZA 2CQZA 4MLMA 3CCGA 3MZOA 4L1JA 1YOYA 2Q14A 4L1JB 4QFZA 1XX7A 3TMCA 3TMDA 4XDSA 1YNBA 1VJ7A 3NR1A 3HI0A 4TO4A 3P3QA 4QFYA 4ZWGA 2O6IA 4DMBA 4R8ZA 3M1TA 2GZ4A 4QG1A 4RXPA 4RXRA 4MDZA 4TNRA 4TO1A 4ME4A 4RXOA 4ZWEA 3TM8A 2PAQA 5TK6A
chains in the Genus database with same CATH superfamily
4MZ7A 3BG2A 3U1NA 2OGIA 5AO0A 5AO4A 4BZCA 5AO3A 3IRHA 4RXSA 4TO0A 4QG4A 4QG0A 4TNPA 2PGSA 5AO2A 5TK8A 4BZBA 3KH1A 5TK7A 2O08A 3TMBA 4TO5A 5AO1A 2PQ7A 4Q2DA 2HEKA 3SK9A 4TO3A 2PAUA 4QG2A 4TNQA 4N6WA 4N71A 3S4LA 3LJXA 1U6ZA 4MLNA 3SKDA 4L7EA 3I7AA 5TKAA 3GW7A 4TNXA 2DQBA 3MEMA 4TO6A 4Q7HA 3KQ5A 3NQWA 4MCWA 4L7WA 4RXQA 3RF0A 1VQRA 4X9EA 4TNYA 4QFXA 4TO2A 4LRLA 3HC1A 5TK9A 2PARA 2FLOA 4TNZA 2CQZA 4MLMA 3CCGA 3MZOA 4L1JA 1YOYA 2Q14A 4QQXA 4L1JB 4QFZA 4QQWA 1XX7A 3TMCA 4QQZA 3TMDA 4XDSA 1YNBA 4Q2CA 1VJ7A 3NR1A 3HI0A 4TO4A 3P3QA 4QFYA 4ZWGA 2O6IA 4DMBA 4R8ZA 3M1TA 2GZ4A 4QG1A 4RXPA 4QQYA 4RXRA 4MDZA 4TNRA 4TO1A 4ME4A 4RXOA 4ZWEA 3TM8A 2PAQA 5TK6A
chains in the Genus database with same CATH topology
4MZ7A 3BG2A 3U1NA 2OGIA 5AO0A 5AO4A 4BZCA 5AO3A 3IRHA 4RXSA 4TO0A 4QG4A 4QG0A 4TNPA 2PGSA 5AO2A 5TK8A 4BZBA 3KH1A 5TK7A 2O08A 3TMBA 4TO5A 5AO1A 2PQ7A 4Q2DA 2HEKA 3SK9A 4TO3A 2PAUA 4QG2A 4TNQA 4N6WA 4N71A 3S4LA 3LJXA 1U6ZA 4MLNA 3SKDA 4L7EA 3I7AA 5TKAA 3GW7A 4TNXA 2DQBA 3MEMA 4TO6A 4Q7HA 3KQ5A 3NQWA 4MCWA 4L7WA 4RXQA 3RF0A 1VQRA 4X9EA 4TNYA 4QFXA 4TO2A 4LRLA 3HC1A 5TK9A 2PARA 2FLOA 4TNZA 2CQZA 4MLMA 3CCGA 3MZOA 4L1JA 1YOYA 2Q14A 4QQXA 4L1JB 4QFZA 4QQWA 1XX7A 3TMCA 4QQZA 3TMDA 4XDSA 1YNBA 4Q2CA 1VJ7A 3NR1A 3HI0A 4TO4A 3P3QA 4QFYA 4ZWGA 2O6IA 4DMBA 4R8ZA 3M1TA 2GZ4A 4QG1A 4RXPA 4QQYA 4RXRA 4MDZA 4TNRA 4TO1A 4ME4A 4RXOA 4ZWEA 3TM8A 2PAQA 5TK6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MZ7 A;  3BG2 A;  3U1N A;  2OGI A;  5AO0 A;  5AO4 A;  4BZC A;  5AO3 A;  3IRH A;  4RXS A;  4TO0 A;  4QG4 A;  4QG0 A;  4TNP A;  2PGS A;  5AO2 A;  5TK8 A;  4BZB A;  3KH1 A;  5TK7 A;  2O08 A;  3TMB A;  4TO5 A;  5AO1 A;  2PQ7 A;  2HEK A;  4TO3 A;  2PAU A;  4QG2 A;  4TNQ A;  4N6W A;  4N71 A;  3LJX A;  1U6Z A;  4MLN A;  4L7E A;  3I7A A;  5TKA A;  4TNX A;  2DQB A;  3MEM A;  4TO6 A;  4Q7H A;  3NQW A;  4MCW A;  4L7W A;  4RXQ A;  3RF0 A;  1VQR A;  4X9E A;  4TNY A;  4QFX A;  4TO2 A;  4LRL A;  3HC1 A;  5TK9 A;  2PAR A;  2FLO A;  4TNZ A;  2CQZ A;  4MLM A;  3CCG A;  3MZO A;  4L1J A;  1YOY A;  2Q14 A;  4L1J B;  4QFZ A;  1XX7 A;  3TMC A;  3TMD A;  4XDS A;  1YNB A;  1VJ7 A;  3NR1 A;  3HI0 A;  4TO4 A;  3P3Q A;  4QFY A;  4ZWG A;  2O6I A;  4DMB A;  4R8Z A;  3M1T A;  2GZ4 A;  4QG1 A;  4RXP A;  4RXR A;  4MDZ A;  4TNR A;  4TO1 A;  4ME4 A;  4RXO A;  4ZWE A;  3TM8 A;  2PAQ A;  5TK6 A; 
#chains in the Genus database with same CATH topology
 4MZ7 A;  3BG2 A;  3U1N A;  2OGI A;  5AO0 A;  5AO4 A;  4BZC A;  5AO3 A;  3IRH A;  4RXS A;  4TO0 A;  4QG4 A;  4QG0 A;  4TNP A;  2PGS A;  5AO2 A;  5TK8 A;  4BZB A;  3KH1 A;  5TK7 A;  2O08 A;  3TMB A;  4TO5 A;  5AO1 A;  2PQ7 A;  4Q2D A;  2HEK A;  3SK9 A;  4TO3 A;  2PAU A;  4QG2 A;  4TNQ A;  4N6W A;  4N71 A;  3S4L A;  3LJX A;  1U6Z A;  4MLN A;  3SKD A;  4L7E A;  3I7A A;  5TKA A;  3GW7 A;  4TNX A;  2DQB A;  3MEM A;  4TO6 A;  4Q7H A;  3KQ5 A;  3NQW A;  4MCW A;  4L7W A;  4RXQ A;  3RF0 A;  1VQR A;  4X9E A;  4TNY A;  4QFX A;  4TO2 A;  4LRL A;  3HC1 A;  5TK9 A;  2PAR A;  2FLO A;  4TNZ A;  2CQZ A;  4MLM A;  3CCG A;  3MZO A;  4L1J A;  1YOY A;  2Q14 A;  4QQX A;  4L1J B;  4QFZ A;  4QQW A;  1XX7 A;  3TMC A;  4QQZ A;  3TMD A;  4XDS A;  1YNB A;  4Q2C A;  1VJ7 A;  3NR1 A;  3HI0 A;  4TO4 A;  3P3Q A;  4QFY A;  4ZWG A;  2O6I A;  4DMB A;  4R8Z A;  3M1T A;  2GZ4 A;  4QG1 A;  4RXP A;  4QQY A;  4RXR A;  4MDZ A;  4TNR A;  4TO1 A;  4ME4 A;  4RXO A;  4ZWE A;  3TM8 A;  2PAQ A;  5TK6 A; 
#chains in the Genus database with same CATH homology
 4MZ7 A;  3BG2 A;  3U1N A;  2OGI A;  5AO0 A;  5AO4 A;  4BZC A;  5AO3 A;  3IRH A;  4RXS A;  4TO0 A;  4QG4 A;  4QG0 A;  4TNP A;  2PGS A;  5AO2 A;  5TK8 A;  4BZB A;  3KH1 A;  5TK7 A;  2O08 A;  3TMB A;  4TO5 A;  5AO1 A;  2PQ7 A;  4Q2D A;  2HEK A;  3SK9 A;  4TO3 A;  2PAU A;  4QG2 A;  4TNQ A;  4N6W A;  4N71 A;  3S4L A;  3LJX A;  1U6Z A;  4MLN A;  3SKD A;  4L7E A;  3I7A A;  5TKA A;  3GW7 A;  4TNX A;  2DQB A;  3MEM A;  4TO6 A;  4Q7H A;  3KQ5 A;  3NQW A;  4MCW A;  4L7W A;  4RXQ A;  3RF0 A;  1VQR A;  4X9E A;  4TNY A;  4QFX A;  4TO2 A;  4LRL A;  3HC1 A;  5TK9 A;  2PAR A;  2FLO A;  4TNZ A;  2CQZ A;  4MLM A;  3CCG A;  3MZO A;  4L1J A;  1YOY A;  2Q14 A;  4QQX A;  4L1J B;  4QFZ A;  4QQW A;  1XX7 A;  3TMC A;  4QQZ A;  3TMD A;  4XDS A;  1YNB A;  4Q2C A;  1VJ7 A;  3NR1 A;  3HI0 A;  4TO4 A;  3P3Q A;  4QFY A;  4ZWG A;  2O6I A;  4DMB A;  4R8Z A;  3M1T A;  2GZ4 A;  4QG1 A;  4RXP A;  4QQY A;  4RXR A;  4MDZ A;  4TNR A;  4TO1 A;  4ME4 A;  4RXO A;  4ZWE A;  3TM8 A;  2PAQ A;  5TK6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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