4X9EA

Deoxyguanosinetriphosphate triphosphohydrolase from escherichia coli with two dna effector molecules
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
505
structure length
499
Chain Sequence
MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords Deoxyguanosinetriphosphate triphosphohydrolase
total genus 192
structure length 499
sequence length 505
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.1.5.1: dGTPase.
pdb deposition date 2014-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01966 HD HD domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3210.10 Mainly Alpha Orthogonal Bundle Hypothetical protein af1432 Hypothetical protein af1432 4x9eA01
2PARA 2Q14A 2DQBA 4TNRA 4MLMA 3NR1A 4QG0A 5TK9A 2HEKA 3MZOA 2GZ4A 4RXQA 1YOYA 4L1JB 4L7WA 4Q7HA 4QG4A 4XDSA 5TKAA 4TNYA 4QFZA 4TO2A 4ME4A 4RXSA 4QFXA 1XX7A 4L1JA 3LJXA 5AO2A 2PQ7A 4MZ7A 4TNZA 5TK8A 1YNBA 4RXOA 2PGSA 3TM8A 3BG2A 1VJ7A 4RXPA 4DMBA 3P3QA 5AO1A 3HI0A 3M1TA 4R8ZA 5TK6A 4TNPA 4ZWGA 3TMBA 5AO3A 4QG1A 3MEMA 3NQWA 2PAQA 3IRHA 4TO5A 5TK7A 4LRLA 4BZCA 4N71A 1U6ZA 5AO4A 4ZWEA 3CCGA 4TO3A 4RXRA 2CQZA 4MLNA 4TNXA 2O6IA 4QFYA 2FLOA 4N6WA 3HC1A 4QG2A 5AO0A 3RF0A 4TO4A 4TNQA 3KH1A 3TMCA 4TO0A 2O08A 2OGIA 4MDZA 4TO6A 4BZBA 2PAUA 4MCWA 3I7AA 4X9EA 3U1NA 4L7EA 4TO1A 3TMDA 1VQRA
chains in the Genus database with same CATH superfamily
2PARA 2Q14A 2DQBA 4TNRA 3S4LA 4MLMA 3NR1A 4QG0A 3GW7A 5TK9A 2HEKA 3MZOA 2GZ4A 4RXQA 1YOYA 4L1JB 4L7WA 3KQ5A 4Q7HA 4QG4A 4XDSA 5TKAA 4TNYA 4QQZA 4QFZA 4TO2A 4ME4A 4RXSA 4QFXA 1XX7A 4L1JA 3LJXA 3SK9A 5AO2A 4Q2CA 2PQ7A 4MZ7A 4Q2DA 5TK8A 4TNZA 4QQWA 1YNBA 4RXOA 3SKDA 4QQYA 2PGSA 3TM8A 3BG2A 1VJ7A 4RXPA 4DMBA 3P3QA 5AO1A 3HI0A 3M1TA 4R8ZA 5TK6A 4TNPA 4ZWGA 3TMBA 5AO3A 4QG1A 3MEMA 3NQWA 2PAQA 3IRHA 4TO5A 5TK7A 4LRLA 4BZCA 4N71A 1U6ZA 5AO4A 4ZWEA 3CCGA 4TO3A 4RXRA 2CQZA 4MLNA 4TNXA 2O6IA 4QFYA 2FLOA 4N6WA 3HC1A 4QG2A 5AO0A 3RF0A 4TO4A 4TNQA 3KH1A 4QQXA 3TMCA 4TO0A 2O08A 2OGIA 4MDZA 4TO6A 4BZBA 2PAUA 4MCWA 3I7AA 4X9EA 3U1NA 4L7EA 4TO1A 3TMDA 1VQRA
chains in the Genus database with same CATH topology
2PARA 2Q14A 2DQBA 4TNRA 3S4LA 4MLMA 3NR1A 4QG0A 3GW7A 5TK9A 2HEKA 3MZOA 2GZ4A 4RXQA 1YOYA 4L1JB 4L7WA 3KQ5A 4Q7HA 4QG4A 4XDSA 5TKAA 4TNYA 4QQZA 4QFZA 4TO2A 4ME4A 4RXSA 4QFXA 1XX7A 4L1JA 3LJXA 3SK9A 5AO2A 4Q2CA 2PQ7A 4MZ7A 4Q2DA 5TK8A 4TNZA 4QQWA 1YNBA 4RXOA 3SKDA 4QQYA 2PGSA 3TM8A 3BG2A 1VJ7A 4RXPA 4DMBA 3P3QA 5AO1A 3HI0A 3M1TA 4R8ZA 5TK6A 4TNPA 4ZWGA 3TMBA 5AO3A 4QG1A 3MEMA 3NQWA 2PAQA 3IRHA 4TO5A 5TK7A 4LRLA 4BZCA 4N71A 1U6ZA 5AO4A 4ZWEA 3CCGA 4TO3A 4RXRA 2CQZA 4MLNA 4TNXA 2O6IA 4QFYA 2FLOA 4N6WA 3HC1A 4QG2A 5AO0A 3RF0A 4TO4A 4TNQA 3KH1A 4QQXA 3TMCA 4TO0A 2O08A 2OGIA 4MDZA 4TO6A 4BZBA 2PAUA 4MCWA 3I7AA 4X9EA 3U1NA 4L7EA 4TO1A 3TMDA 1VQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PAR A;  2Q14 A;  2DQB A;  4TNR A;  4MLM A;  3NR1 A;  4QG0 A;  5TK9 A;  2HEK A;  3MZO A;  2GZ4 A;  4RXQ A;  1YOY A;  4L1J B;  4L7W A;  4Q7H A;  4QG4 A;  4XDS A;  5TKA A;  4TNY A;  4QFZ A;  4TO2 A;  4ME4 A;  4RXS A;  4QFX A;  1XX7 A;  4L1J A;  3LJX A;  5AO2 A;  2PQ7 A;  4MZ7 A;  4TNZ A;  5TK8 A;  1YNB A;  4RXO A;  2PGS A;  3TM8 A;  3BG2 A;  1VJ7 A;  4RXP A;  4DMB A;  3P3Q A;  5AO1 A;  3HI0 A;  3M1T A;  4R8Z A;  5TK6 A;  4TNP A;  4ZWG A;  3TMB A;  5AO3 A;  4QG1 A;  3MEM A;  3NQW A;  2PAQ A;  3IRH A;  4TO5 A;  5TK7 A;  4LRL A;  4BZC A;  4N71 A;  1U6Z A;  5AO4 A;  4ZWE A;  3CCG A;  4TO3 A;  4RXR A;  2CQZ A;  4MLN A;  4TNX A;  2O6I A;  4QFY A;  2FLO A;  4N6W A;  3HC1 A;  4QG2 A;  5AO0 A;  3RF0 A;  4TO4 A;  4TNQ A;  3KH1 A;  3TMC A;  4TO0 A;  2O08 A;  2OGI A;  4MDZ A;  4TO6 A;  4BZB A;  2PAU A;  4MCW A;  3I7A A;  4X9E A;  3U1N A;  4L7E A;  4TO1 A;  3TMD A;  1VQR A; 
#chains in the Genus database with same CATH topology
 2PAR A;  2Q14 A;  2DQB A;  4TNR A;  3S4L A;  4MLM A;  3NR1 A;  4QG0 A;  3GW7 A;  5TK9 A;  2HEK A;  3MZO A;  2GZ4 A;  4RXQ A;  1YOY A;  4L1J B;  4L7W A;  3KQ5 A;  4Q7H A;  4QG4 A;  4XDS A;  5TKA A;  4TNY A;  4QQZ A;  4QFZ A;  4TO2 A;  4ME4 A;  4RXS A;  4QFX A;  1XX7 A;  4L1J A;  3LJX A;  3SK9 A;  5AO2 A;  4Q2C A;  2PQ7 A;  4MZ7 A;  4Q2D A;  5TK8 A;  4TNZ A;  4QQW A;  1YNB A;  4RXO A;  3SKD A;  4QQY A;  2PGS A;  3TM8 A;  3BG2 A;  1VJ7 A;  4RXP A;  4DMB A;  3P3Q A;  5AO1 A;  3HI0 A;  3M1T A;  4R8Z A;  5TK6 A;  4TNP A;  4ZWG A;  3TMB A;  5AO3 A;  4QG1 A;  3MEM A;  3NQW A;  2PAQ A;  3IRH A;  4TO5 A;  5TK7 A;  4LRL A;  4BZC A;  4N71 A;  1U6Z A;  5AO4 A;  4ZWE A;  3CCG A;  4TO3 A;  4RXR A;  2CQZ A;  4MLN A;  4TNX A;  2O6I A;  4QFY A;  2FLO A;  4N6W A;  3HC1 A;  4QG2 A;  5AO0 A;  3RF0 A;  4TO4 A;  4TNQ A;  3KH1 A;  4QQX A;  3TMC A;  4TO0 A;  2O08 A;  2OGI A;  4MDZ A;  4TO6 A;  4BZB A;  2PAU A;  4MCW A;  3I7A A;  4X9E A;  3U1N A;  4L7E A;  4TO1 A;  3TMD A;  1VQR A; 
#chains in the Genus database with same CATH homology
 2PAR A;  2Q14 A;  2DQB A;  4TNR A;  3S4L A;  4MLM A;  3NR1 A;  4QG0 A;  3GW7 A;  5TK9 A;  2HEK A;  3MZO A;  2GZ4 A;  4RXQ A;  1YOY A;  4L1J B;  4L7W A;  3KQ5 A;  4Q7H A;  4QG4 A;  4XDS A;  5TKA A;  4TNY A;  4QQZ A;  4QFZ A;  4TO2 A;  4ME4 A;  4RXS A;  4QFX A;  1XX7 A;  4L1J A;  3LJX A;  3SK9 A;  5AO2 A;  4Q2C A;  2PQ7 A;  4MZ7 A;  4Q2D A;  5TK8 A;  4TNZ A;  4QQW A;  1YNB A;  4RXO A;  3SKD A;  4QQY A;  2PGS A;  3TM8 A;  3BG2 A;  1VJ7 A;  4RXP A;  4DMB A;  3P3Q A;  5AO1 A;  3HI0 A;  3M1T A;  4R8Z A;  5TK6 A;  4TNP A;  4ZWG A;  3TMB A;  5AO3 A;  4QG1 A;  3MEM A;  3NQW A;  2PAQ A;  3IRH A;  4TO5 A;  5TK7 A;  4LRL A;  4BZC A;  4N71 A;  1U6Z A;  5AO4 A;  4ZWE A;  3CCG A;  4TO3 A;  4RXR A;  2CQZ A;  4MLN A;  4TNX A;  2O6I A;  4QFY A;  2FLO A;  4N6W A;  3HC1 A;  4QG2 A;  5AO0 A;  3RF0 A;  4TO4 A;  4TNQ A;  3KH1 A;  4QQX A;  3TMC A;  4TO0 A;  2O08 A;  2OGI A;  4MDZ A;  4TO6 A;  4BZB A;  2PAU A;  4MCW A;  3I7A A;  4X9E A;  3U1N A;  4L7E A;  4TO1 A;  3TMD A;  1VQR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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