1D0GR

Crystal structure of death receptor 5 (dr5) bound to apo2l/trail
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
108
structure length
108
Chain Sequence
SSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.
pubmed doi rcsb
molecule keywords DEATH RECEPTOR-5
molecule tags Apoptosis
source organism Homo sapiens
total genus 15
structure length 108
sequence length 108
chains with identical sequence S, T
ec nomenclature
pdb deposition date 1999-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d0gR03
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d0gR01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d0gR02
3MI8D 5DMJA 2H9GR 3TJEF 4YN0A 3U3PA 4MSVB 3U3SA 5IHLA 4FHQA 1EXTA 2AW2B 4KGGC 3QO4A 5BNQR 5CIRE 1FT4A 1ZA3R 2HEYR 3X3FA 1NCFA 2X10A 3ALQR 1D4VA 3MBWA 3U3VA 5L36B 3U3QA 4BK5A 3IJ2X 4RSUD 4N90R 4KGQC 4MXWR 4BK4A 4GIQR 3WVTA 1TNRR 2HEVR 3BUKC 3K51B 3ME4A 3QBQB 4I9XC 4J6GC 4M4PA 2UWIA 1SG1X 4E4DR 4OD2S 1D0GR 3QD6R 3MHDD 3THMF 3FL7A 4M4RA 3URFZ 3U3TA 1JMAB 1DU3A 3ME2R
chains in the Genus database with same CATH superfamily
3MI8D 5DMJA 2H9GR 3TJEF 4YN0A 3U3PA 4MSVB 3U3SA 5IHLA 4FHQA 1EXTA 2AW2B 2E4UA 4KGGC 3QO4A 2E4YA 2E4XA 5BNQR 5CIRE 1FT4A 1ZA3R 2HEYR 3X3FA 1NCFA 2X10A 3ALQR 1D4VA 3MBWA 3U3VA 5L36B 3U3QA 4BK5A 3IJ2X 4RSUD 4N90R 4KGQC 4MXWR 4BK4A 4GIQR 3WVTA 1TNRR 2HEVR 3BUKC 3K51B 3ME4A 3QBQB 4I9XC 4J6GC 4M4PA 2UWIA 1SG1X 4E4DR 4OD2S 1D0GR 2E4VA 3MHDD 3QD6R 3THMF 3FL7A 4M4RA 2QR6A 3URFZ 3U3TA 1JMAB 2E4WA 1DU3A 3ME2R
chains in the Genus database with same CATH topology
3MI8D 5DMJA 2H9GR 3TJEF 4YN0A 3U3PA 4MSVB 3U3SA 5IHLA 4FHQA 1EXTA 2AW2B 4KGGC 3QO4A 5BNQR 5CIRE 1FT4A 1ZA3R 2HEYR 3X3FA 1NCFA 2X10A 3ALQR 1D4VA 3MBWA 3U3VA 5L36B 3U3QA 4BK5A 3IJ2X 4RSUD 4N90R 4KGQC 4MXWR 4BK4A 4GIQR 3WVTA 1TNRR 2HEVR 3BUKC 3K51B 3ME4A 3QBQB 4I9XC 4J6GC 4M4PA 2UWIA 1SG1X 4E4DR 4OD2S 1D0GR 3QD6R 3MHDD 3THMF 3FL7A 4M4RA 3URFZ 3U3TA 1JMAB 1DU3A 3ME2R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MI8 D;  5DMJ A;  2H9G R;  3TJE F;  4YN0 A;  3U3P A;  4MSV B;  3U3S A;  5IHL A;  4FHQ A;  1EXT A;  2AW2 B;  4KGG C;  3QO4 A;  5BNQ R;  5CIR E;  1FT4 A;  1ZA3 R;  2HEY R;  3X3F A;  1NCF A;  2X10 A;  3ALQ R;  1D4V A;  3MBW A;  3U3V A;  5L36 B;  3U3Q A;  4BK5 A;  3IJ2 X;  4RSU D;  4N90 R;  4KGQ C;  4MXW R;  4BK4 A;  4GIQ R;  3WVT A;  1TNR R;  2HEV R;  3BUK C;  3K51 B;  3ME4 A;  3QBQ B;  4I9X C;  4J6G C;  4M4P A;  2UWI A;  1SG1 X;  4E4D R;  4OD2 S;  1D0G R;  3QD6 R;  3MHD D;  3THM F;  3FL7 A;  4M4R A;  3URF Z;  3U3T A;  1JMA B;  1DU3 A;  3ME2 R; 
#chains in the Genus database with same CATH topology
 3MI8 D;  5DMJ A;  2H9G R;  3TJE F;  4YN0 A;  3U3P A;  4MSV B;  3U3S A;  5IHL A;  4FHQ A;  1EXT A;  2AW2 B;  2E4U A;  4KGG C;  3QO4 A;  2E4Y A;  2E4X A;  5BNQ R;  5CIR E;  1FT4 A;  1ZA3 R;  2HEY R;  3X3F A;  1NCF A;  2X10 A;  3ALQ R;  1D4V A;  3MBW A;  3U3V A;  5L36 B;  3U3Q A;  4BK5 A;  3IJ2 X;  4RSU D;  4N90 R;  4KGQ C;  4MXW R;  4BK4 A;  4GIQ R;  3WVT A;  1TNR R;  2HEV R;  3BUK C;  3K51 B;  3ME4 A;  3QBQ B;  4I9X C;  4J6G C;  4M4P A;  2UWI A;  1SG1 X;  4E4D R;  4OD2 S;  1D0G R;  2E4V A;  3MHD D;  3QD6 R;  3THM F;  3FL7 A;  4M4R A;  2QR6 A;  3URF Z;  3U3T A;  1JMA B;  2E4W A;  1DU3 A;  3ME2 R; 
#chains in the Genus database with same CATH homology
 3MI8 D;  5DMJ A;  2H9G R;  3TJE F;  4YN0 A;  3U3P A;  4MSV B;  3U3S A;  5IHL A;  4FHQ A;  1EXT A;  2AW2 B;  4KGG C;  3QO4 A;  5BNQ R;  5CIR E;  1FT4 A;  1ZA3 R;  2HEY R;  3X3F A;  1NCF A;  2X10 A;  3ALQ R;  1D4V A;  3MBW A;  3U3V A;  5L36 B;  3U3Q A;  4BK5 A;  3IJ2 X;  4RSU D;  4N90 R;  4KGQ C;  4MXW R;  4BK4 A;  4GIQ R;  3WVT A;  1TNR R;  2HEV R;  3BUK C;  3K51 B;  3ME4 A;  3QBQ B;  4I9X C;  4J6G C;  4M4P A;  2UWI A;  1SG1 X;  4E4D R;  4OD2 S;  1D0G R;  3QD6 R;  3MHD D;  3THM F;  3FL7 A;  4M4R A;  3URF Z;  3U3T A;  1JMA B;  1DU3 A;  3ME2 R; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...