1D0GR

Crystal structure of death receptor 5 (dr5) bound to apo2l/trail
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
108
structure length
108
Chain Sequence
SSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Apoptosis
molecule keywords DEATH RECEPTOR-5
publication title Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.
pubmed doi rcsb
source organism Homo sapiens
total genus 15
structure length 108
sequence length 108
chains with identical sequence S, T
ec nomenclature
pdb deposition date 1999-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d0gR03
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d0gR01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d0gR02
3MHDD 4M4RA 5L36B 3IJ2X 1ZA3R 4GIQR 5CIRE 4MXWR 5IHLA 1EXTA 3X3FA 2AW2B 3THMF 4FHQA 3QO4A 1JMAB 2H9GR 1D4VA 3K51B 3MI8D 3QBQB 3ME4A 4KGGC 4YN0A 2HEVR 3MBWA 4BK5A 4BK4A 4J6GC 4E4DR 4OD2S 3WVTA 4N90R 3FL7A 2X10A 1FT4A 3U3QA 3U3VA 4M4PA 4I9XC 1SG1X 3BUKC 3URFZ 4MSVB 3U3PA 5DMJA 4RSUD 3ME2R 1NCFA 1TNRR 3U3SA 3TJEF 1D0GR 3ALQR 2UWIA 3U3TA 1DU3A 4KGQC 2HEYR 3QD6R 5BNQR
chains in the Genus database with same CATH superfamily
3MHDD 2E4UA 4M4RA 5L36B 2E4VA 1ZA3R 3IJ2X 4GIQR 5CIRE 4MXWR 5IHLA 1EXTA 3X3FA 2AW2B 3THMF 4FHQA 2E4XA 3QO4A 1JMAB 2H9GR 1D4VA 3K51B 3MI8D 3QBQB 3ME4A 4KGGC 4YN0A 2HEVR 3MBWA 4BK5A 4BK4A 4J6GC 4E4DR 4OD2S 3WVTA 4N90R 3FL7A 1FT4A 2X10A 3U3QA 3U3VA 4M4PA 4I9XC 1SG1X 3BUKC 3URFZ 4MSVB 3U3PA 5DMJA 2E4WA 4RSUD 3ME2R 1NCFA 1TNRR 3U3SA 3TJEF 2E4YA 1D0GR 3ALQR 2UWIA 3U3TA 1DU3A 2QR6A 4KGQC 2HEYR 3QD6R 5BNQR
chains in the Genus database with same CATH topology
3MHDD 4M4RA 5L36B 3IJ2X 1ZA3R 4GIQR 5CIRE 4MXWR 5IHLA 1EXTA 3X3FA 2AW2B 3THMF 4FHQA 3QO4A 1JMAB 2H9GR 1D4VA 3K51B 3MI8D 3QBQB 3ME4A 4KGGC 4YN0A 2HEVR 3MBWA 4BK5A 4BK4A 4J6GC 4E4DR 4OD2S 3WVTA 4N90R 3FL7A 2X10A 1FT4A 3U3QA 3U3VA 4M4PA 4I9XC 1SG1X 3BUKC 3URFZ 4MSVB 3U3PA 5DMJA 4RSUD 3ME2R 1NCFA 1TNRR 3U3SA 3TJEF 1D0GR 3ALQR 2UWIA 3U3TA 1DU3A 4KGQC 2HEYR 3QD6R 5BNQR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MHD D;  4M4R A;  5L36 B;  3IJ2 X;  1ZA3 R;  4GIQ R;  5CIR E;  4MXW R;  5IHL A;  1EXT A;  3X3F A;  2AW2 B;  3THM F;  4FHQ A;  3QO4 A;  1JMA B;  2H9G R;  1D4V A;  3K51 B;  3MI8 D;  3QBQ B;  3ME4 A;  4KGG C;  4YN0 A;  2HEV R;  3MBW A;  4BK5 A;  4BK4 A;  4J6G C;  4E4D R;  4OD2 S;  3WVT A;  4N90 R;  3FL7 A;  2X10 A;  1FT4 A;  3U3Q A;  3U3V A;  4M4P A;  4I9X C;  1SG1 X;  3BUK C;  3URF Z;  4MSV B;  3U3P A;  5DMJ A;  4RSU D;  3ME2 R;  1NCF A;  1TNR R;  3U3S A;  3TJE F;  1D0G R;  3ALQ R;  2UWI A;  3U3T A;  1DU3 A;  4KGQ C;  2HEY R;  3QD6 R;  5BNQ R; 
#chains in the Genus database with same CATH topology
 3MHD D;  2E4U A;  4M4R A;  5L36 B;  2E4V A;  1ZA3 R;  3IJ2 X;  4GIQ R;  5CIR E;  4MXW R;  5IHL A;  1EXT A;  3X3F A;  2AW2 B;  3THM F;  4FHQ A;  2E4X A;  3QO4 A;  1JMA B;  2H9G R;  1D4V A;  3K51 B;  3MI8 D;  3QBQ B;  3ME4 A;  4KGG C;  4YN0 A;  2HEV R;  3MBW A;  4BK5 A;  4BK4 A;  4J6G C;  4E4D R;  4OD2 S;  3WVT A;  4N90 R;  3FL7 A;  1FT4 A;  2X10 A;  3U3Q A;  3U3V A;  4M4P A;  4I9X C;  1SG1 X;  3BUK C;  3URF Z;  4MSV B;  3U3P A;  5DMJ A;  2E4W A;  4RSU D;  3ME2 R;  1NCF A;  1TNR R;  3U3S A;  3TJE F;  2E4Y A;  1D0G R;  3ALQ R;  2UWI A;  3U3T A;  1DU3 A;  2QR6 A;  4KGQ C;  2HEY R;  3QD6 R;  5BNQ R; 
#chains in the Genus database with same CATH homology
 3MHD D;  4M4R A;  5L36 B;  3IJ2 X;  1ZA3 R;  4GIQ R;  5CIR E;  4MXW R;  5IHL A;  1EXT A;  3X3F A;  2AW2 B;  3THM F;  4FHQ A;  3QO4 A;  1JMA B;  2H9G R;  1D4V A;  3K51 B;  3MI8 D;  3QBQ B;  3ME4 A;  4KGG C;  4YN0 A;  2HEV R;  3MBW A;  4BK5 A;  4BK4 A;  4J6G C;  4E4D R;  4OD2 S;  3WVT A;  4N90 R;  3FL7 A;  2X10 A;  1FT4 A;  3U3Q A;  3U3V A;  4M4P A;  4I9X C;  1SG1 X;  3BUK C;  3URF Z;  4MSV B;  3U3P A;  5DMJ A;  4RSU D;  3ME2 R;  1NCF A;  1TNR R;  3U3S A;  3TJE F;  1D0G R;  3ALQ R;  2UWI A;  3U3T A;  1DU3 A;  4KGQ C;  2HEY R;  3QD6 R;  5BNQ R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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