4KGQC

Crystal structure of a human light loop mutant in complex with dcr3
Total Genus 32
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
167
structure length
167
Chain Sequence
TPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSTGHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Immune system
molecule keywords Tumor necrosis factor receptor superfamily member 6B
publication title Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
pubmed doi rcsb
source organism Homo sapiens
total genus 32
structure length 167
sequence length 167
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4kgqC02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4kgqC01
1D4VA 2HEVR 4MXWR 3ALQR 5DMJA 3U3SA 5IHLA 4M4RA 5CIRE 3ME4A 3U3TA 3THMF 4N90R 4E4DR 2H9GR 2AW2B 3QBQB 3TJEF 2UWIA 3U3VA 4KGGC 3K51B 1NCFA 1JMAB 4KGQC 2X10A 4MSVB 4RSUD 1DU3A 4I9XC 4BK4A 3ME2R 1EXTA 3MI8D 4GIQR 4J6GC 3U3PA 3MHDD 1SG1X 4YN0A 1D0GR 3IJ2X 3FL7A 3U3QA 3QD6R 3QO4A 3URFZ 3MBWA 3WVTA 5BNQR 1TNRR 1ZA3R 3X3FA 4M4PA 2HEYR 5L36B 4OD2S 4BK5A 4FHQA 3BUKC 1FT4A
chains in the Genus database with same CATH superfamily
2E4VA 1D4VA 2HEVR 4MXWR 3ALQR 5DMJA 3U3SA 5IHLA 4M4RA 5CIRE 3ME4A 3U3TA 3THMF 4N90R 4E4DR 2H9GR 2AW2B 2E4YA 3QBQB 2UWIA 3TJEF 4KGGC 3K51B 1NCFA 1JMAB 4KGQC 2X10A 4MSVB 4RSUD 1DU3A 2E4WA 2QR6A 4I9XC 4BK4A 3ME2R 1EXTA 3MI8D 4GIQR 4J6GC 3U3PA 3MHDD 1SG1X 4YN0A 1D0GR 3IJ2X 3FL7A 3U3QA 3QD6R 3QO4A 3URFZ 3MBWA 2E4XA 3U3VA 3WVTA 5BNQR 1TNRR 1ZA3R 3X3FA 4M4PA 2HEYR 5L36B 4OD2S 4BK5A 4FHQA 3BUKC 1FT4A 2E4UA
chains in the Genus database with same CATH topology
1D4VA 2HEVR 4MXWR 3ALQR 5DMJA 3U3SA 5IHLA 4M4RA 5CIRE 3ME4A 3U3TA 3THMF 4N90R 4E4DR 2H9GR 2AW2B 3QBQB 3TJEF 2UWIA 3U3VA 4KGGC 3K51B 1NCFA 1JMAB 4KGQC 2X10A 4MSVB 4RSUD 1DU3A 4I9XC 4BK4A 3ME2R 1EXTA 3MI8D 4GIQR 4J6GC 3U3PA 3MHDD 1SG1X 4YN0A 1D0GR 3IJ2X 3FL7A 3U3QA 3QD6R 3QO4A 3URFZ 3MBWA 3WVTA 5BNQR 1TNRR 1ZA3R 3X3FA 4M4PA 2HEYR 5L36B 4OD2S 4BK5A 4FHQA 3BUKC 1FT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D4V A;  2HEV R;  4MXW R;  3ALQ R;  5DMJ A;  3U3S A;  5IHL A;  4M4R A;  5CIR E;  3ME4 A;  3U3T A;  3THM F;  4N90 R;  4E4D R;  2H9G R;  2AW2 B;  3QBQ B;  3TJE F;  2UWI A;  3U3V A;  4KGG C;  3K51 B;  1NCF A;  1JMA B;  4KGQ C;  2X10 A;  4MSV B;  4RSU D;  1DU3 A;  4I9X C;  4BK4 A;  3ME2 R;  1EXT A;  3MI8 D;  4GIQ R;  4J6G C;  3U3P A;  3MHD D;  1SG1 X;  4YN0 A;  1D0G R;  3IJ2 X;  3FL7 A;  3U3Q A;  3QD6 R;  3QO4 A;  3URF Z;  3MBW A;  3WVT A;  5BNQ R;  1TNR R;  1ZA3 R;  3X3F A;  4M4P A;  2HEY R;  5L36 B;  4OD2 S;  4BK5 A;  4FHQ A;  3BUK C;  1FT4 A; 
#chains in the Genus database with same CATH topology
 2E4V A;  1D4V A;  2HEV R;  4MXW R;  3ALQ R;  5DMJ A;  3U3S A;  5IHL A;  4M4R A;  5CIR E;  3ME4 A;  3U3T A;  3THM F;  4N90 R;  4E4D R;  2H9G R;  2AW2 B;  2E4Y A;  3QBQ B;  2UWI A;  3TJE F;  4KGG C;  3K51 B;  1NCF A;  1JMA B;  4KGQ C;  2X10 A;  4MSV B;  4RSU D;  1DU3 A;  2E4W A;  2QR6 A;  4I9X C;  4BK4 A;  3ME2 R;  1EXT A;  3MI8 D;  4GIQ R;  4J6G C;  3U3P A;  3MHD D;  1SG1 X;  4YN0 A;  1D0G R;  3IJ2 X;  3FL7 A;  3U3Q A;  3QD6 R;  3QO4 A;  3URF Z;  3MBW A;  2E4X A;  3U3V A;  3WVT A;  5BNQ R;  1TNR R;  1ZA3 R;  3X3F A;  4M4P A;  2HEY R;  5L36 B;  4OD2 S;  4BK5 A;  4FHQ A;  3BUK C;  1FT4 A;  2E4U A; 
#chains in the Genus database with same CATH homology
 1D4V A;  2HEV R;  4MXW R;  3ALQ R;  5DMJ A;  3U3S A;  5IHL A;  4M4R A;  5CIR E;  3ME4 A;  3U3T A;  3THM F;  4N90 R;  4E4D R;  2H9G R;  2AW2 B;  3QBQ B;  3TJE F;  2UWI A;  3U3V A;  4KGG C;  3K51 B;  1NCF A;  1JMA B;  4KGQ C;  2X10 A;  4MSV B;  4RSU D;  1DU3 A;  4I9X C;  4BK4 A;  3ME2 R;  1EXT A;  3MI8 D;  4GIQ R;  4J6G C;  3U3P A;  3MHD D;  1SG1 X;  4YN0 A;  1D0G R;  3IJ2 X;  3FL7 A;  3U3Q A;  3QD6 R;  3QO4 A;  3URF Z;  3MBW A;  3WVT A;  5BNQ R;  1TNR R;  1ZA3 R;  3X3F A;  4M4P A;  2HEY R;  5L36 B;  4OD2 S;  4BK5 A;  4FHQ A;  3BUK C;  1FT4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...