1D4VA

Crystal structure of trail-dr5 complex
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
117
structure length
117
Chain Sequence
PQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords TNF-RELATED APOPTOSIS INDUCING LIGAND
total genus 17
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 1999-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d4vA03
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d4vA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1d4vA02
1D0GR 4J6GC 1TNRR 4KGQC 1DU3A 1SG1X 3K51B 4I9XC 3MBWA 1D4VA 4M4RA 3IJ2X 3ME2R 4MXWR 4OD2S 5IHLA 3MI8D 3FL7A 5DMJA 3THMF 3WVTA 3ALQR 2HEYR 2HEVR 1JMAB 4M4PA 2AW2B 4E4DR 5CIRE 3U3SA 5L36B 3U3VA 3QBQB 3MHDD 3URFZ 1EXTA 4GIQR 4MSVB 3X3FA 4FHQA 3U3PA 2X10A 1ZA3R 3U3QA 1NCFA 2H9GR 3ME4A 1FT4A 4BK4A 3QO4A 3TJEF 5BNQR 4RSUD 4YN0A 2UWIA 3U3TA 4N90R 4KGGC 4BK5A 3QD6R 3BUKC
chains in the Genus database with same CATH superfamily
1D0GR 4J6GC 1TNRR 4KGQC 1DU3A 1SG1X 3K51B 4I9XC 3MBWA 1D4VA 4M4RA 3IJ2X 3ME2R 4MXWR 4OD2S 5IHLA 3MI8D 3FL7A 5DMJA 3THMF 3WVTA 3ALQR 2HEYR 2HEVR 1JMAB 4M4PA 2AW2B 4E4DR 5CIRE 3U3SA 5L36B 3U3VA 3QBQB 3MHDD 3URFZ 1EXTA 4GIQR 4MSVB 3X3FA 4FHQA 3U3PA 2X10A 1ZA3R 3U3QA 1NCFA 2H9GR 2E4UA 3ME4A 1FT4A 4BK4A 3QO4A 3TJEF 2E4YA 5BNQR 2E4VA 4RSUD 2QR6A 4YN0A 2UWIA 3U3TA 2E4WA 4KGGC 4N90R 3QD6R 4BK5A 2E4XA 3BUKC
chains in the Genus database with same CATH topology
1D0GR 4J6GC 1TNRR 4KGQC 1DU3A 1SG1X 3K51B 4I9XC 3MBWA 1D4VA 4M4RA 3IJ2X 3ME2R 4MXWR 4OD2S 5IHLA 3MI8D 3FL7A 5DMJA 3THMF 3WVTA 3ALQR 2HEYR 2HEVR 1JMAB 4M4PA 2AW2B 4E4DR 5CIRE 3U3SA 5L36B 3U3VA 3QBQB 3MHDD 3URFZ 1EXTA 4GIQR 4MSVB 3X3FA 4FHQA 3U3PA 2X10A 1ZA3R 3U3QA 1NCFA 2H9GR 3ME4A 1FT4A 4BK4A 3QO4A 3TJEF 5BNQR 4RSUD 4YN0A 2UWIA 3U3TA 4N90R 4KGGC 4BK5A 3QD6R 3BUKC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D0G R;  4J6G C;  1TNR R;  4KGQ C;  1DU3 A;  1SG1 X;  3K51 B;  4I9X C;  3MBW A;  1D4V A;  4M4R A;  3IJ2 X;  3ME2 R;  4MXW R;  4OD2 S;  5IHL A;  3MI8 D;  3FL7 A;  5DMJ A;  3THM F;  3WVT A;  3ALQ R;  2HEY R;  2HEV R;  1JMA B;  4M4P A;  2AW2 B;  4E4D R;  5CIR E;  3U3S A;  5L36 B;  3U3V A;  3QBQ B;  3MHD D;  3URF Z;  1EXT A;  4GIQ R;  4MSV B;  3X3F A;  4FHQ A;  3U3P A;  2X10 A;  1ZA3 R;  3U3Q A;  1NCF A;  2H9G R;  3ME4 A;  1FT4 A;  4BK4 A;  3QO4 A;  3TJE F;  5BNQ R;  4RSU D;  4YN0 A;  2UWI A;  3U3T A;  4N90 R;  4KGG C;  4BK5 A;  3QD6 R;  3BUK C; 
#chains in the Genus database with same CATH topology
 1D0G R;  4J6G C;  1TNR R;  4KGQ C;  1DU3 A;  1SG1 X;  3K51 B;  4I9X C;  3MBW A;  1D4V A;  4M4R A;  3IJ2 X;  3ME2 R;  4MXW R;  4OD2 S;  5IHL A;  3MI8 D;  3FL7 A;  5DMJ A;  3THM F;  3WVT A;  3ALQ R;  2HEY R;  2HEV R;  1JMA B;  4M4P A;  2AW2 B;  4E4D R;  5CIR E;  3U3S A;  5L36 B;  3U3V A;  3QBQ B;  3MHD D;  3URF Z;  1EXT A;  4GIQ R;  4MSV B;  3X3F A;  4FHQ A;  3U3P A;  2X10 A;  1ZA3 R;  3U3Q A;  1NCF A;  2H9G R;  2E4U A;  3ME4 A;  1FT4 A;  4BK4 A;  3QO4 A;  3TJE F;  2E4Y A;  5BNQ R;  2E4V A;  4RSU D;  2QR6 A;  4YN0 A;  2UWI A;  3U3T A;  2E4W A;  4KGG C;  4N90 R;  3QD6 R;  4BK5 A;  2E4X A;  3BUK C; 
#chains in the Genus database with same CATH homology
 1D0G R;  4J6G C;  1TNR R;  4KGQ C;  1DU3 A;  1SG1 X;  3K51 B;  4I9X C;  3MBW A;  1D4V A;  4M4R A;  3IJ2 X;  3ME2 R;  4MXW R;  4OD2 S;  5IHL A;  3MI8 D;  3FL7 A;  5DMJ A;  3THM F;  3WVT A;  3ALQ R;  2HEY R;  2HEV R;  1JMA B;  4M4P A;  2AW2 B;  4E4D R;  5CIR E;  3U3S A;  5L36 B;  3U3V A;  3QBQ B;  3MHD D;  3URF Z;  1EXT A;  4GIQ R;  4MSV B;  3X3F A;  4FHQ A;  3U3P A;  2X10 A;  1ZA3 R;  3U3Q A;  1NCF A;  2H9G R;  3ME4 A;  1FT4 A;  4BK4 A;  3QO4 A;  3TJE F;  5BNQ R;  4RSU D;  4YN0 A;  2UWI A;  3U3T A;  4N90 R;  4KGG C;  4BK5 A;  3QD6 R;  3BUK C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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