1DU3A

Crystal structure of trail-sdr5
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
103
structure length
90
Chain Sequence
SSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKDCTPWSDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords DEATH RECEPTOR 5
total genus 14
structure length 90
sequence length 103
chains with identical sequence B, C, G, H, I
ec nomenclature
pdb deposition date 2000-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1du3A02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1du3A01
1FT4A 3U3QA 3THMF 4M4PA 4GIQR 3QBQB 3U3VA 3MI8D 1JMAB 3U3SA 5BNQR 2X10A 1TNRR 5CIRE 5L36B 1SG1X 3K51B 4BK5A 5IHLA 3MHDD 1NCFA 4RSUD 3URFZ 3FL7A 4I9XC 4M4RA 3ME2R 3WVTA 4YN0A 3ALQR 4KGGC 4MXWR 1D4VA 3ME4A 3IJ2X 4OD2S 3MBWA 3U3PA 4E4DR 3BUKC 4MSVB 4BK4A 2UWIA 4FHQA 1ZA3R 2H9GR 3X3FA 2HEVR 3U3TA 3QO4A 1D0GR 4J6GC 2AW2B 4KGQC 5DMJA 3QD6R 3TJEF 1DU3A 1EXTA 4N90R 2HEYR
chains in the Genus database with same CATH superfamily
1FT4A 3U3QA 3THMF 2E4XA 4M4PA 4GIQR 3QBQB 3U3VA 2E4VA 3MI8D 1JMAB 3U3SA 2E4YA 2X10A 1TNRR 5CIRE 5BNQR 1SG1X 5L36B 2E4WA 3K51B 4BK5A 5IHLA 3MHDD 1NCFA 2QR6A 4RSUD 3URFZ 3FL7A 4I9XC 4M4RA 3ME2R 3WVTA 4YN0A 3ALQR 4KGGC 4MXWR 1D4VA 3ME4A 3IJ2X 4OD2S 3MBWA 3U3PA 4E4DR 3BUKC 4MSVB 4BK4A 2UWIA 4FHQA 1ZA3R 2H9GR 3X3FA 2HEVR 3U3TA 3QO4A 1D0GR 4J6GC 2AW2B 4KGQC 5DMJA 2E4UA 3QD6R 3TJEF 1DU3A 1EXTA 4N90R 2HEYR
chains in the Genus database with same CATH topology
1FT4A 3U3QA 3THMF 4M4PA 4GIQR 3QBQB 3U3VA 3MI8D 1JMAB 3U3SA 5BNQR 2X10A 1TNRR 5CIRE 5L36B 1SG1X 3K51B 4BK5A 5IHLA 3MHDD 1NCFA 4RSUD 3URFZ 3FL7A 4I9XC 4M4RA 3ME2R 3WVTA 4YN0A 3ALQR 4KGGC 4MXWR 1D4VA 3ME4A 3IJ2X 4OD2S 3MBWA 3U3PA 4E4DR 3BUKC 4MSVB 4BK4A 2UWIA 4FHQA 1ZA3R 2H9GR 3X3FA 2HEVR 3U3TA 3QO4A 1D0GR 4J6GC 2AW2B 4KGQC 5DMJA 3QD6R 3TJEF 1DU3A 1EXTA 4N90R 2HEYR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FT4 A;  3U3Q A;  3THM F;  4M4P A;  4GIQ R;  3QBQ B;  3U3V A;  3MI8 D;  1JMA B;  3U3S A;  5BNQ R;  2X10 A;  1TNR R;  5CIR E;  5L36 B;  1SG1 X;  3K51 B;  4BK5 A;  5IHL A;  3MHD D;  1NCF A;  4RSU D;  3URF Z;  3FL7 A;  4I9X C;  4M4R A;  3ME2 R;  3WVT A;  4YN0 A;  3ALQ R;  4KGG C;  4MXW R;  1D4V A;  3ME4 A;  3IJ2 X;  4OD2 S;  3MBW A;  3U3P A;  4E4D R;  3BUK C;  4MSV B;  4BK4 A;  2UWI A;  4FHQ A;  1ZA3 R;  2H9G R;  3X3F A;  2HEV R;  3U3T A;  3QO4 A;  1D0G R;  4J6G C;  2AW2 B;  4KGQ C;  5DMJ A;  3QD6 R;  3TJE F;  1DU3 A;  1EXT A;  4N90 R;  2HEY R; 
#chains in the Genus database with same CATH topology
 1FT4 A;  3U3Q A;  3THM F;  2E4X A;  4M4P A;  4GIQ R;  3QBQ B;  3U3V A;  2E4V A;  3MI8 D;  1JMA B;  3U3S A;  2E4Y A;  2X10 A;  1TNR R;  5CIR E;  5BNQ R;  1SG1 X;  5L36 B;  2E4W A;  3K51 B;  4BK5 A;  5IHL A;  3MHD D;  1NCF A;  2QR6 A;  4RSU D;  3URF Z;  3FL7 A;  4I9X C;  4M4R A;  3ME2 R;  3WVT A;  4YN0 A;  3ALQ R;  4KGG C;  4MXW R;  1D4V A;  3ME4 A;  3IJ2 X;  4OD2 S;  3MBW A;  3U3P A;  4E4D R;  3BUK C;  4MSV B;  4BK4 A;  2UWI A;  4FHQ A;  1ZA3 R;  2H9G R;  3X3F A;  2HEV R;  3U3T A;  3QO4 A;  1D0G R;  4J6G C;  2AW2 B;  4KGQ C;  5DMJ A;  2E4U A;  3QD6 R;  3TJE F;  1DU3 A;  1EXT A;  4N90 R;  2HEY R; 
#chains in the Genus database with same CATH homology
 1FT4 A;  3U3Q A;  3THM F;  4M4P A;  4GIQ R;  3QBQ B;  3U3V A;  3MI8 D;  1JMA B;  3U3S A;  5BNQ R;  2X10 A;  1TNR R;  5CIR E;  5L36 B;  1SG1 X;  3K51 B;  4BK5 A;  5IHL A;  3MHD D;  1NCF A;  4RSU D;  3URF Z;  3FL7 A;  4I9X C;  4M4R A;  3ME2 R;  3WVT A;  4YN0 A;  3ALQ R;  4KGG C;  4MXW R;  1D4V A;  3ME4 A;  3IJ2 X;  4OD2 S;  3MBW A;  3U3P A;  4E4D R;  3BUK C;  4MSV B;  4BK4 A;  2UWI A;  4FHQ A;  1ZA3 R;  2H9G R;  3X3F A;  2HEV R;  3U3T A;  3QO4 A;  1D0G R;  4J6G C;  2AW2 B;  4KGQ C;  5DMJ A;  3QD6 R;  3TJE F;  1DU3 A;  1EXT A;  4N90 R;  2HEY R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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