The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
20
|
sequence length |
140
|
structure length |
140
|
Chain Sequence |
MDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENEC
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha.
pubmed doi rcsb |
| molecule tags |
Signaling protein
|
| source organism |
Homo sapiens
|
| molecule keywords |
SOLUBLE TUMOR NECROSIS FACTOR RECEPTOR 1
|
| total genus |
20
|
| structure length |
140
|
| sequence length |
140
|
| chains with identical sequence |
B
|
| ec nomenclature | |
| pdb deposition date | 2000-09-11 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00020 | TNFR_c6 | TNFR/NGFR cysteine-rich region |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Ribbon | Tumor Necrosis Factor Receptor, subunit A; domain 2 | Tumor Necrosis Factor Receptor, subunit A, domain 2 | ||
| Mainly Beta | Ribbon | Tumor Necrosis Factor Receptor, subunit A; domain 2 | Tumor Necrosis Factor Receptor, subunit A, domain 2 |
#chains in the Genus database with same CATH superfamily 2AW2 B; 3U3Q A; 1DU3 A; 1JMA B; 3ALQ R; 3ME4 A; 3MI8 D; 4FHQ A; 3U3S A; 4OD2 S; 2UWI A; 3U3T A; 4E4D R; 4M4P A; 1ZA3 R; 3IJ2 X; 1NCF A; 3MBW A; 3TJE F; 5IHL A; 3U3P A; 3ME2 R; 4KGG C; 1FT4 A; 3QBQ B; 3X3F A; 5BNQ R; 3QD6 R; 4J6G C; 3FL7 A; 4YN0 A; 4N90 R; 3QO4 A; 4BK4 A; 5L36 B; 4KGQ C; 4BK5 A; 3WVT A; 5CIR E; 5DMJ A; 2X10 A; 1EXT A; 1D4V A; 3K51 B; 4I9X C; 4MXW R; 3URF Z; 1TNR R; 4GIQ R; 3MHD D; 3U3V A; 2H9G R; 3BUK C; 3THM F; 1D0G R; 4MSV B; 2HEV R; 2HEY R; 4RSU D; 4M4R A; 1SG1 X; #chains in the Genus database with same CATH topology 2QR6 A; 2AW2 B; 3U3Q A; 1DU3 A; 1JMA B; 3ALQ R; 2E4X A; 3ME4 A; 3MI8 D; 4FHQ A; 3U3S A; 4OD2 S; 2E4V A; 2UWI A; 2E4U A; 3U3T A; 4M4P A; 1ZA3 R; 4E4D R; 2E4W A; 3IJ2 X; 1NCF A; 3MBW A; 3TJE F; 5IHL A; 3U3P A; 3ME2 R; 4KGG C; 1FT4 A; 3QBQ B; 3X3F A; 5BNQ R; 3QD6 R; 4J6G C; 3FL7 A; 4YN0 A; 4N90 R; 3QO4 A; 4BK4 A; 5L36 B; 4KGQ C; 4BK5 A; 3WVT A; 5CIR E; 5DMJ A; 2X10 A; 1EXT A; 1D4V A; 3K51 B; 4I9X C; 4MXW R; 3URF Z; 2E4Y A; 1TNR R; 4GIQ R; 3MHD D; 3U3V A; 2H9G R; 3BUK C; 3THM F; 1D0G R; 4MSV B; 2HEV R; 2HEY R; 4RSU D; 4M4R A; 1SG1 X; #chains in the Genus database with same CATH homology 2AW2 B; 3U3Q A; 1DU3 A; 1JMA B; 3ALQ R; 3ME4 A; 3MI8 D; 4FHQ A; 3U3S A; 4OD2 S; 2UWI A; 3U3T A; 4E4D R; 4M4P A; 1ZA3 R; 3IJ2 X; 1NCF A; 3MBW A; 3TJE F; 5IHL A; 3U3P A; 3ME2 R; 4KGG C; 1FT4 A; 3QBQ B; 3X3F A; 5BNQ R; 3QD6 R; 4J6G C; 3FL7 A; 4YN0 A; 4N90 R; 3QO4 A; 4BK4 A; 5L36 B; 4KGQ C; 4BK5 A; 3WVT A; 5CIR E; 5DMJ A; 2X10 A; 1EXT A; 1D4V A; 3K51 B; 4I9X C; 4MXW R; 3URF Z; 1TNR R; 4GIQ R; 3MHD D; 3U3V A; 2H9G R; 3BUK C; 3THM F; 1D0G R; 4MSV B; 2HEV R; 2HEY R; 4RSU D; 4M4R A; 1SG1 X;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
