1G8RA

Moea
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
403
structure length
403
Chain Sequence
LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin.
pubmed doi rcsb
molecule tags Metal binding protein
molecule keywords MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN
total genus 104
structure length 403
sequence length 403
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2000-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 1g8rA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 1g8rA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 1g8rA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 1g8rA02
4UOCA 4U90A 5ERTA 2NQRA 1O8QA 2IS8A 4LHBA 1JLJA 3MCJA 3RFQA 4CTAA 1UUXA 2FU3A 3OI9A 1MKZA 1FC5A 5ERRA 2NROA 3MCHA 1DI6A 4UUWA 3K6AA 3PZYA 1G8RA 1O8OA 5G2RA 3IWTA 3TCRA 4UUXA 1O8NA 1WU2A 2FTSA 3MCIA 4NWOA 1XI8A 4TK4A 5ERVA 4TK1A 4U91A 4CTAB 5ERUA 2G4RA 2F7WA 3KBQA 2NQNA 2F7YA 2NRSA 4TK3A 1IHCA 2NQMA 5ERSA 2X3LA 5ERQA 1Y5EA 1EAVA 1UUYA 2NQKA 5G2SA 2NRPA 2NQQA 4PD1A 1T3EA 1UZ5A 4CT9A 2G2CA 2NQVA 4CT8A 2PBQA 1G8LA 1R2KA 4TWGA 2QQ1A 4PD0A 1DI7A 4XCWA 2NQSA 2NQUA
chains in the Genus database with same CATH superfamily
4UOCA 4U90A 5ERTA 2NQRA 1O8QA 2IS8A 4LHBA 1JLJA 1IW7D 3MCJA 3RFQA 4CTAA 1UUXA 2FU3A 3OI9A 1MKZA 1FC5A 5ERRA 2NROA 3MCHA 1DI6A 4UUWA 4NWBA 5D6GA 3K6AA 3PZYA 1G8RA 1O8OA 5G2RA 3IWTA 3TCRA 4UUXA 1O8NA 1WU2A 2FTSA 3MCIA 4NWOA 1YZYA 3JSYA 1XI8A 3DQQA 4TK4A 5ERVA 4TK1A 4U91A 4CTAB 5ERUA 2G4RA 2F7WA 3KBQA 2NQNA 2F7YA 2NRSA 4TK3A 1IHCA 2NQMA 5ERSA 2X3LA 5ERQA 1Y5EA 5DMHA 1EAVA 1UUYA 2NQKA 5G2SA 2NRPA 1I6VD 2NQQA 4PD1A 1T3EA 1HQMD 1UZ5A 4CT9A 2G2CA 2NQVA 4CT8A 2PBQA 5D8HB 1G8LA 1R2KA 4TWGA 2QQ1A 4PD0A 1DI7A 4XCWA 2NQSA 2NQUA
chains in the Genus database with same CATH topology
4UOCA 4U90A 5ERTA 2NQRA 1O8QA 2IS8A 4LHBA 1JLJA 1IW7D 3MCJA 3RFQA 4CTAA 1UUXA 2FU3A 3OI9A 1MKZA 1FC5A 5ERRA 2NROA 3MCHA 1DI6A 4UUWA 4NWBA 5D6GA 3K6AA 3PZYA 1G8RA 1O8OA 5G2RA 3IWTA 3TCRA 4UUXA 1O8NA 1WU2A 2FTSA 3MCIA 4NWOA 3JSYA 1XI8A 4TK4A 5ERVA 4TK1A 4U91A 4CTAB 5ERUA 2G4RA 2F7WA 3KBQA 2NQNA 2F7YA 2NRSA 4TK3A 1IHCA 2NQMA 5ERSA 2X3LA 5ERQA 1Y5EA 1EAVA 1UUYA 2NQKA 5G2SA 2NRPA 1I6VD 2NQQA 4PD1A 1T3EA 1HQMD 1UZ5A 4CT9A 2G2CA 2NQVA 4CT8A 2PBQA 5D8HB 1G8LA 1R2KA 4TWGA 2QQ1A 4PD0A 1DI7A 4XCWA 2NQSA 2NQUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UOC A;  4U90 A;  5ERT A;  2NQR A;  1O8Q A;  2IS8 A;  4LHB A;  1JLJ A;  3MCJ A;  3RFQ A;  4CTA A;  1UUX A;  2FU3 A;  3OI9 A;  1MKZ A;  1FC5 A;  5ERR A;  2NRO A;  3MCH A;  1DI6 A;  4UUW A;  3K6A A;  3PZY A;  1G8R A;  1O8O A;  5G2R A;  3IWT A;  3TCR A;  4UUX A;  1O8N A;  1WU2 A;  2FTS A;  3MCI A;  4NWO A;  1XI8 A;  4TK4 A;  5ERV A;  4TK1 A;  4U91 A;  4CTA B;  5ERU A;  2G4R A;  2F7W A;  3KBQ A;  2NQN A;  2F7Y A;  2NRS A;  4TK3 A;  1IHC A;  2NQM A;  5ERS A;  2X3L A;  5ERQ A;  1Y5E A;  1EAV A;  1UUY A;  2NQK A;  5G2S A;  2NRP A;  2NQQ A;  4PD1 A;  1T3E A;  1UZ5 A;  4CT9 A;  2G2C A;  2NQV A;  4CT8 A;  2PBQ A;  1G8L A;  1R2K A;  4TWG A;  2QQ1 A;  4PD0 A;  1DI7 A;  4XCW A;  2NQS A;  2NQU A; 
#chains in the Genus database with same CATH topology
 4UOC A;  4U90 A;  5ERT A;  2NQR A;  1O8Q A;  2IS8 A;  4LHB A;  1JLJ A;  1IW7 D;  3MCJ A;  3RFQ A;  4CTA A;  1UUX A;  2FU3 A;  3OI9 A;  1MKZ A;  1FC5 A;  5ERR A;  2NRO A;  3MCH A;  1DI6 A;  4UUW A;  4NWB A;  5D6G A;  3K6A A;  3PZY A;  1G8R A;  1O8O A;  5G2R A;  3IWT A;  3TCR A;  4UUX A;  1O8N A;  1WU2 A;  2FTS A;  3MCI A;  4NWO A;  1YZY A;  3JSY A;  1XI8 A;  3DQQ A;  4TK4 A;  5ERV A;  4TK1 A;  4U91 A;  4CTA B;  5ERU A;  2G4R A;  2F7W A;  3KBQ A;  2NQN A;  2F7Y A;  2NRS A;  4TK3 A;  1IHC A;  2NQM A;  5ERS A;  2X3L A;  5ERQ A;  1Y5E A;  5DMH A;  1EAV A;  1UUY A;  2NQK A;  5G2S A;  2NRP A;  1I6V D;  2NQQ A;  4PD1 A;  1T3E A;  1HQM D;  1UZ5 A;  4CT9 A;  2G2C A;  2NQV A;  4CT8 A;  2PBQ A;  5D8H B;  1G8L A;  1R2K A;  4TWG A;  2QQ1 A;  4PD0 A;  1DI7 A;  4XCW A;  2NQS A;  2NQU A; 
#chains in the Genus database with same CATH homology
 4UOC A;  4U90 A;  5ERT A;  2NQR A;  1O8Q A;  2IS8 A;  4LHB A;  1JLJ A;  1IW7 D;  3MCJ A;  3RFQ A;  4CTA A;  1UUX A;  2FU3 A;  3OI9 A;  1MKZ A;  1FC5 A;  5ERR A;  2NRO A;  3MCH A;  1DI6 A;  4UUW A;  4NWB A;  5D6G A;  3K6A A;  3PZY A;  1G8R A;  1O8O A;  5G2R A;  3IWT A;  3TCR A;  4UUX A;  1O8N A;  1WU2 A;  2FTS A;  3MCI A;  4NWO A;  3JSY A;  1XI8 A;  4TK4 A;  5ERV A;  4TK1 A;  4U91 A;  4CTA B;  5ERU A;  2G4R A;  2F7W A;  3KBQ A;  2NQN A;  2F7Y A;  2NRS A;  4TK3 A;  1IHC A;  2NQM A;  5ERS A;  2X3L A;  5ERQ A;  1Y5E A;  1EAV A;  1UUY A;  2NQK A;  5G2S A;  2NRP A;  1I6V D;  2NQQ A;  4PD1 A;  1T3E A;  1HQM D;  1UZ5 A;  4CT9 A;  2G2C A;  2NQV A;  4CT8 A;  2PBQ A;  5D8H B;  1G8L A;  1R2K A;  4TWG A;  2QQ1 A;  4PD0 A;  1DI7 A;  4XCW A;  2NQS A;  2NQU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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