5ERQA

Gephyrin e domain at 1.55 angstrom resolution
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
419
structure length
417
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 109
structure length 417
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5erqA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5erqA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5erqA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5erqA02
5ERUA 3OI9A 1IHCA 5ERSA 3MCJA 4CTAA 1EAVA 3K6AA 1UZ5A 4UOCA 2NRPA 2F7YA 4UUWA 2NQKA 4LHBA 1T3EA 4NWOA 5ERRA 1DI6A 2G4RA 4CT9A 2NQRA 2NQVA 1G8LA 4XCWA 4PD1A 4TK4A 1DI7A 2NQUA 4TWGA 4CTAB 4CT8A 1FC5A 2NQNA 4U91A 5G2RA 2PBQA 5ERVA 4TK1A 1O8QA 2NQSA 1MKZA 2NQQA 1UUXA 2X3LA 2NRSA 2F7WA 1Y5EA 1O8OA 2FU3A 3MCIA 3IWTA 3MCHA 2QQ1A 5ERQA 3PZYA 5ERTA 1JLJA 4PD0A 2IS8A 3RFQA 4U90A 2NROA 4TK3A 3KBQA 1UUYA 5G2SA 1R2KA 1WU2A 2FTSA 3TCRA 1XI8A 2NQMA 2G2CA 1O8NA 1G8RA 4UUXA
chains in the Genus database with same CATH superfamily
5ERUA 3OI9A 1IHCA 5ERSA 3MCJA 4CTAA 1EAVA 3K6AA 1UZ5A 4UOCA 2NRPA 2F7YA 4UUWA 2NQKA 3JSYA 4LHBA 1T3EA 4NWOA 5ERRA 1DI6A 2G4RA 4CT9A 2NQRA 2NQVA 1G8LA 4XCWA 4PD1A 4TK4A 1DI7A 1I6VD 2NQUA 4TWGA 5DMHA 4NWBA 4CTAB 4CT8A 1FC5A 2NQNA 4U91A 5G2RA 2PBQA 5ERVA 1YZYA 5D6GA 4TK1A 1O8QA 2NQSA 1MKZA 2NQQA 1IW7D 1UUXA 2X3LA 1HQMD 2NRSA 2F7WA 1Y5EA 1O8OA 5D8HB 2FU3A 3MCIA 3IWTA 3DQQA 3MCHA 2QQ1A 5ERQA 3PZYA 5ERTA 1JLJA 4PD0A 2IS8A 3RFQA 4U90A 2NROA 4TK3A 3KBQA 1UUYA 5G2SA 1R2KA 1WU2A 2FTSA 3TCRA 1XI8A 2NQMA 2G2CA 1O8NA 1G8RA 4UUXA
chains in the Genus database with same CATH topology
5ERUA 3OI9A 1IHCA 5ERSA 3MCJA 4CTAA 1EAVA 3K6AA 1UZ5A 4UOCA 2NRPA 2F7YA 4UUWA 2NQKA 3JSYA 4LHBA 1T3EA 4NWOA 5ERRA 1DI6A 2G4RA 4CT9A 2NQRA 2NQVA 1G8LA 4XCWA 4PD1A 4TK4A 1DI7A 1I6VD 2NQUA 4TWGA 4NWBA 4CTAB 4CT8A 1FC5A 2NQNA 4U91A 5G2RA 2PBQA 5ERVA 5D6GA 4TK1A 1O8QA 2NQSA 1MKZA 2NQQA 1IW7D 1UUXA 2X3LA 1HQMD 2NRSA 2F7WA 1Y5EA 1O8OA 5D8HB 2FU3A 3MCIA 3IWTA 3MCHA 2QQ1A 5ERQA 3PZYA 5ERTA 1JLJA 4PD0A 2IS8A 3RFQA 4U90A 2NROA 4TK3A 3KBQA 1UUYA 5G2SA 1R2KA 1WU2A 2FTSA 3TCRA 1XI8A 2NQMA 2G2CA 1O8NA 1G8RA 4UUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ERU A;  3OI9 A;  1IHC A;  5ERS A;  3MCJ A;  4CTA A;  1EAV A;  3K6A A;  1UZ5 A;  4UOC A;  2NRP A;  2F7Y A;  4UUW A;  2NQK A;  4LHB A;  1T3E A;  4NWO A;  5ERR A;  1DI6 A;  2G4R A;  4CT9 A;  2NQR A;  2NQV A;  1G8L A;  4XCW A;  4PD1 A;  4TK4 A;  1DI7 A;  2NQU A;  4TWG A;  4CTA B;  4CT8 A;  1FC5 A;  2NQN A;  4U91 A;  5G2R A;  2PBQ A;  5ERV A;  4TK1 A;  1O8Q A;  2NQS A;  1MKZ A;  2NQQ A;  1UUX A;  2X3L A;  2NRS A;  2F7W A;  1Y5E A;  1O8O A;  2FU3 A;  3MCI A;  3IWT A;  3MCH A;  2QQ1 A;  5ERQ A;  3PZY A;  5ERT A;  1JLJ A;  4PD0 A;  2IS8 A;  3RFQ A;  4U90 A;  2NRO A;  4TK3 A;  3KBQ A;  1UUY A;  5G2S A;  1R2K A;  1WU2 A;  2FTS A;  3TCR A;  1XI8 A;  2NQM A;  2G2C A;  1O8N A;  1G8R A;  4UUX A; 
#chains in the Genus database with same CATH topology
 5ERU A;  3OI9 A;  1IHC A;  5ERS A;  3MCJ A;  4CTA A;  1EAV A;  3K6A A;  1UZ5 A;  4UOC A;  2NRP A;  2F7Y A;  4UUW A;  2NQK A;  3JSY A;  4LHB A;  1T3E A;  4NWO A;  5ERR A;  1DI6 A;  2G4R A;  4CT9 A;  2NQR A;  2NQV A;  1G8L A;  4XCW A;  4PD1 A;  4TK4 A;  1DI7 A;  1I6V D;  2NQU A;  4TWG A;  5DMH A;  4NWB A;  4CTA B;  4CT8 A;  1FC5 A;  2NQN A;  4U91 A;  5G2R A;  2PBQ A;  5ERV A;  1YZY A;  5D6G A;  4TK1 A;  1O8Q A;  2NQS A;  1MKZ A;  2NQQ A;  1IW7 D;  1UUX A;  2X3L A;  1HQM D;  2NRS A;  2F7W A;  1Y5E A;  1O8O A;  5D8H B;  2FU3 A;  3MCI A;  3IWT A;  3DQQ A;  3MCH A;  2QQ1 A;  5ERQ A;  3PZY A;  5ERT A;  1JLJ A;  4PD0 A;  2IS8 A;  3RFQ A;  4U90 A;  2NRO A;  4TK3 A;  3KBQ A;  1UUY A;  5G2S A;  1R2K A;  1WU2 A;  2FTS A;  3TCR A;  1XI8 A;  2NQM A;  2G2C A;  1O8N A;  1G8R A;  4UUX A; 
#chains in the Genus database with same CATH homology
 5ERU A;  3OI9 A;  1IHC A;  5ERS A;  3MCJ A;  4CTA A;  1EAV A;  3K6A A;  1UZ5 A;  4UOC A;  2NRP A;  2F7Y A;  4UUW A;  2NQK A;  3JSY A;  4LHB A;  1T3E A;  4NWO A;  5ERR A;  1DI6 A;  2G4R A;  4CT9 A;  2NQR A;  2NQV A;  1G8L A;  4XCW A;  4PD1 A;  4TK4 A;  1DI7 A;  1I6V D;  2NQU A;  4TWG A;  4NWB A;  4CTA B;  4CT8 A;  1FC5 A;  2NQN A;  4U91 A;  5G2R A;  2PBQ A;  5ERV A;  5D6G A;  4TK1 A;  1O8Q A;  2NQS A;  1MKZ A;  2NQQ A;  1IW7 D;  1UUX A;  2X3L A;  1HQM D;  2NRS A;  2F7W A;  1Y5E A;  1O8O A;  5D8H B;  2FU3 A;  3MCI A;  3IWT A;  3MCH A;  2QQ1 A;  5ERQ A;  3PZY A;  5ERT A;  1JLJ A;  4PD0 A;  2IS8 A;  3RFQ A;  4U90 A;  2NRO A;  4TK3 A;  3KBQ A;  1UUY A;  5G2S A;  1R2K A;  1WU2 A;  2FTS A;  3TCR A;  1XI8 A;  2NQM A;  2G2C A;  1O8N A;  1G8R A;  4UUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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