1T3EA

Structural basis of dynamic glycine receptor clustering
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
419
structure length
412
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Structural protein/signaling protein
source organism Rattus norvegicus
publication title Structural basis of dynamic glycine receptor clustering by gephyrin
pubmed doi rcsb
molecule keywords Gephyrin
total genus 95
structure length 412
sequence length 419
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2004-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 1t3eA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 1t3eA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 1t3eA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 1t3eA02
1UZ5A 4TK3A 4PD0A 2PBQA 1O8NA 5G2SA 4LHBA 1DI6A 3RFQA 3MCJA 4NWOA 1IHCA 2X3LA 2NROA 4CT8A 4XCWA 2F7WA 2NRSA 2NQVA 1DI7A 3TCRA 2G2CA 4CTAA 2NQQA 1R2KA 1T3EA 2IS8A 1XI8A 1WU2A 5ERTA 3PZYA 1G8LA 2NQKA 4UUXA 3OI9A 4CT9A 3IWTA 2FU3A 4TK1A 2FTSA 1JLJA 5ERUA 2NQRA 1MKZA 4UUWA 1G8RA 1UUXA 3MCIA 5G2RA 2F7YA 1EAVA 4U91A 5ERRA 2QQ1A 5ERSA 4TWGA 2NRPA 2NQNA 5ERQA 3K6AA 4U90A 1Y5EA 2NQMA 2G4RA 4UOCA 4PD1A 5ERVA 1O8OA 1O8QA 4TK4A 1UUYA 4CTAB 2NQSA 1FC5A 3KBQA 3MCHA 2NQUA
chains in the Genus database with same CATH superfamily
1UZ5A 4TK3A 4PD0A 2PBQA 1O8NA 5DMHA 5G2SA 1IW7D 4LHBA 1DI6A 3RFQA 3MCJA 4NWOA 4NWBA 1I6VD 1IHCA 2X3LA 2NROA 4CT8A 4XCWA 2F7WA 2NRSA 5D6GA 2NQVA 1DI7A 3TCRA 1YZYA 2G2CA 4CTAA 2NQQA 3JSYA 5D8HB 1R2KA 1T3EA 2IS8A 1XI8A 1WU2A 5ERTA 3PZYA 1G8LA 2NQKA 4UUXA 3OI9A 4CT9A 3IWTA 2FU3A 4TK1A 2FTSA 1JLJA 5ERUA 2NQRA 3DQQA 1MKZA 4UUWA 1G8RA 1UUXA 3MCIA 5G2RA 2F7YA 1EAVA 4U91A 5ERRA 2QQ1A 5ERSA 4TWGA 2NRPA 2NQNA 5ERQA 3K6AA 1HQMD 4U90A 1Y5EA 2NQMA 2G4RA 4UOCA 4PD1A 5ERVA 1O8OA 1O8QA 4TK4A 1UUYA 4CTAB 2NQSA 1FC5A 3KBQA 3MCHA 2NQUA
chains in the Genus database with same CATH topology
1UZ5A 4TK3A 4PD0A 2PBQA 1O8NA 5G2SA 1IW7D 4LHBA 1DI6A 3RFQA 3MCJA 4NWOA 4NWBA 1I6VD 1IHCA 2X3LA 2NROA 4CT8A 4XCWA 2F7WA 2NRSA 5D6GA 2NQVA 1DI7A 3TCRA 2G2CA 4CTAA 2NQQA 3JSYA 5D8HB 1R2KA 1T3EA 2IS8A 1XI8A 1WU2A 5ERTA 3PZYA 1G8LA 2NQKA 4UUXA 3OI9A 4CT9A 3IWTA 2FU3A 4TK1A 2FTSA 1JLJA 5ERUA 2NQRA 1MKZA 4UUWA 1G8RA 1UUXA 3MCIA 5G2RA 2F7YA 1EAVA 4U91A 5ERRA 2QQ1A 5ERSA 4TWGA 2NRPA 2NQNA 5ERQA 3K6AA 1HQMD 4U90A 1Y5EA 2NQMA 2G4RA 4UOCA 4PD1A 5ERVA 1O8OA 1O8QA 4TK4A 1UUYA 4CTAB 2NQSA 1FC5A 3KBQA 3MCHA 2NQUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UZ5 A;  4TK3 A;  4PD0 A;  2PBQ A;  1O8N A;  5G2S A;  4LHB A;  1DI6 A;  3RFQ A;  3MCJ A;  4NWO A;  1IHC A;  2X3L A;  2NRO A;  4CT8 A;  4XCW A;  2F7W A;  2NRS A;  2NQV A;  1DI7 A;  3TCR A;  2G2C A;  4CTA A;  2NQQ A;  1R2K A;  1T3E A;  2IS8 A;  1XI8 A;  1WU2 A;  5ERT A;  3PZY A;  1G8L A;  2NQK A;  4UUX A;  3OI9 A;  4CT9 A;  3IWT A;  2FU3 A;  4TK1 A;  2FTS A;  1JLJ A;  5ERU A;  2NQR A;  1MKZ A;  4UUW A;  1G8R A;  1UUX A;  3MCI A;  5G2R A;  2F7Y A;  1EAV A;  4U91 A;  5ERR A;  2QQ1 A;  5ERS A;  4TWG A;  2NRP A;  2NQN A;  5ERQ A;  3K6A A;  4U90 A;  1Y5E A;  2NQM A;  2G4R A;  4UOC A;  4PD1 A;  5ERV A;  1O8O A;  1O8Q A;  4TK4 A;  1UUY A;  4CTA B;  2NQS A;  1FC5 A;  3KBQ A;  3MCH A;  2NQU A; 
#chains in the Genus database with same CATH topology
 1UZ5 A;  4TK3 A;  4PD0 A;  2PBQ A;  1O8N A;  5DMH A;  5G2S A;  1IW7 D;  4LHB A;  1DI6 A;  3RFQ A;  3MCJ A;  4NWO A;  4NWB A;  1I6V D;  1IHC A;  2X3L A;  2NRO A;  4CT8 A;  4XCW A;  2F7W A;  2NRS A;  5D6G A;  2NQV A;  1DI7 A;  3TCR A;  1YZY A;  2G2C A;  4CTA A;  2NQQ A;  3JSY A;  5D8H B;  1R2K A;  1T3E A;  2IS8 A;  1XI8 A;  1WU2 A;  5ERT A;  3PZY A;  1G8L A;  2NQK A;  4UUX A;  3OI9 A;  4CT9 A;  3IWT A;  2FU3 A;  4TK1 A;  2FTS A;  1JLJ A;  5ERU A;  2NQR A;  3DQQ A;  1MKZ A;  4UUW A;  1G8R A;  1UUX A;  3MCI A;  5G2R A;  2F7Y A;  1EAV A;  4U91 A;  5ERR A;  2QQ1 A;  5ERS A;  4TWG A;  2NRP A;  2NQN A;  5ERQ A;  3K6A A;  1HQM D;  4U90 A;  1Y5E A;  2NQM A;  2G4R A;  4UOC A;  4PD1 A;  5ERV A;  1O8O A;  1O8Q A;  4TK4 A;  1UUY A;  4CTA B;  2NQS A;  1FC5 A;  3KBQ A;  3MCH A;  2NQU A; 
#chains in the Genus database with same CATH homology
 1UZ5 A;  4TK3 A;  4PD0 A;  2PBQ A;  1O8N A;  5G2S A;  1IW7 D;  4LHB A;  1DI6 A;  3RFQ A;  3MCJ A;  4NWO A;  4NWB A;  1I6V D;  1IHC A;  2X3L A;  2NRO A;  4CT8 A;  4XCW A;  2F7W A;  2NRS A;  5D6G A;  2NQV A;  1DI7 A;  3TCR A;  2G2C A;  4CTA A;  2NQQ A;  3JSY A;  5D8H B;  1R2K A;  1T3E A;  2IS8 A;  1XI8 A;  1WU2 A;  5ERT A;  3PZY A;  1G8L A;  2NQK A;  4UUX A;  3OI9 A;  4CT9 A;  3IWT A;  2FU3 A;  4TK1 A;  2FTS A;  1JLJ A;  5ERU A;  2NQR A;  1MKZ A;  4UUW A;  1G8R A;  1UUX A;  3MCI A;  5G2R A;  2F7Y A;  1EAV A;  4U91 A;  5ERR A;  2QQ1 A;  5ERS A;  4TWG A;  2NRP A;  2NQN A;  5ERQ A;  3K6A A;  1HQM D;  4U90 A;  1Y5E A;  2NQM A;  2G4R A;  4UOC A;  4PD1 A;  5ERV A;  1O8O A;  1O8Q A;  4TK4 A;  1UUY A;  4CTA B;  2NQS A;  1FC5 A;  3KBQ A;  3MCH A;  2NQU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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