2FTSA

Crystal structure of the glycine receptor-gephyrin complex
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
419
structure length
419
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Deciphering the structural framework of glycine receptor anchoring by gephyrin.
pubmed doi rcsb
molecule tags Structural protein
source organism Rattus norvegicus
molecule keywords gephyrin
total genus 95
structure length 419
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2ftsA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2ftsA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2ftsA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2ftsA02
1Y5EA 1IHCA 2NQVA 1G8LA 3OI9A 5G2SA 2F7YA 2NRPA 1O8OA 4NWOA 1UUYA 1MKZA 2NQSA 5ERUA 3MCJA 2QQ1A 2FTSA 5ERTA 1UUXA 4CT8A 5ERVA 4CT9A 1JLJA 4TK4A 1WU2A 1UZ5A 1O8QA 1XI8A 3KBQA 1R2KA 2NQUA 2NQQA 1FC5A 4TWGA 2IS8A 1T3EA 3IWTA 2NRSA 1G8RA 4U90A 2NROA 4XCWA 2X3LA 5ERSA 2PBQA 4U91A 1DI6A 3TCRA 3MCIA 1O8NA 4TK3A 1EAVA 5G2RA 4CTAB 2F7WA 2G4RA 5ERQA 3K6AA 3PZYA 4TK1A 3RFQA 2NQNA 4LHBA 2FU3A 4CTAA 4PD0A 2G2CA 5ERRA 1DI7A 4UOCA 2NQKA 4UUWA 4PD1A 3MCHA 2NQMA 2NQRA 4UUXA
chains in the Genus database with same CATH superfamily
1Y5EA 1IHCA 2NQVA 1G8LA 3OI9A 5G2SA 2F7YA 3JSYA 2NRPA 1O8OA 4NWOA 1UUYA 1MKZA 2NQSA 5ERUA 3MCJA 2QQ1A 2FTSA 5ERTA 1UUXA 4CT8A 5ERVA 4CT9A 1JLJA 1I6VD 4TK4A 5D6GA 1YZYA 1WU2A 1UZ5A 1O8QA 1XI8A 3KBQA 1R2KA 2NQUA 2NQQA 1FC5A 4TWGA 2IS8A 1T3EA 3IWTA 2NRSA 1G8RA 4U90A 2NROA 4XCWA 1HQMD 2X3LA 5ERSA 2PBQA 4U91A 1DI6A 3TCRA 3MCIA 5D8HB 1O8NA 4TK3A 1EAVA 5G2RA 4NWBA 4CTAB 2F7WA 2G4RA 5ERQA 5DMHA 3K6AA 3PZYA 4TK1A 3RFQA 2NQNA 4LHBA 2FU3A 1IW7D 3DQQA 4CTAA 4PD0A 2G2CA 5ERRA 1DI7A 4UOCA 2NQKA 4UUWA 4PD1A 3MCHA 2NQMA 2NQRA 4UUXA
chains in the Genus database with same CATH topology
1Y5EA 1IHCA 2NQVA 1G8LA 3OI9A 5G2SA 2F7YA 3JSYA 2NRPA 1O8OA 4NWOA 1UUYA 1MKZA 2NQSA 5ERUA 3MCJA 2QQ1A 2FTSA 5ERTA 1UUXA 4CT8A 5ERVA 4CT9A 1JLJA 1I6VD 4TK4A 5D6GA 1WU2A 1UZ5A 1O8QA 1XI8A 3KBQA 1R2KA 2NQUA 2NQQA 1FC5A 4TWGA 2IS8A 1T3EA 3IWTA 2NRSA 1G8RA 4U90A 2NROA 4XCWA 1HQMD 2X3LA 5ERSA 2PBQA 4U91A 1DI6A 3TCRA 3MCIA 5D8HB 1O8NA 4TK3A 1EAVA 5G2RA 4NWBA 4CTAB 2F7WA 2G4RA 5ERQA 3K6AA 3PZYA 4TK1A 3RFQA 2NQNA 4LHBA 2FU3A 1IW7D 4CTAA 4PD0A 2G2CA 5ERRA 1DI7A 4UOCA 2NQKA 4UUWA 4PD1A 3MCHA 2NQMA 2NQRA 4UUXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y5E A;  1IHC A;  2NQV A;  1G8L A;  3OI9 A;  5G2S A;  2F7Y A;  2NRP A;  1O8O A;  4NWO A;  1UUY A;  1MKZ A;  2NQS A;  5ERU A;  3MCJ A;  2QQ1 A;  2FTS A;  5ERT A;  1UUX A;  4CT8 A;  5ERV A;  4CT9 A;  1JLJ A;  4TK4 A;  1WU2 A;  1UZ5 A;  1O8Q A;  1XI8 A;  3KBQ A;  1R2K A;  2NQU A;  2NQQ A;  1FC5 A;  4TWG A;  2IS8 A;  1T3E A;  3IWT A;  2NRS A;  1G8R A;  4U90 A;  2NRO A;  4XCW A;  2X3L A;  5ERS A;  2PBQ A;  4U91 A;  1DI6 A;  3TCR A;  3MCI A;  1O8N A;  4TK3 A;  1EAV A;  5G2R A;  4CTA B;  2F7W A;  2G4R A;  5ERQ A;  3K6A A;  3PZY A;  4TK1 A;  3RFQ A;  2NQN A;  4LHB A;  2FU3 A;  4CTA A;  4PD0 A;  2G2C A;  5ERR A;  1DI7 A;  4UOC A;  2NQK A;  4UUW A;  4PD1 A;  3MCH A;  2NQM A;  2NQR A;  4UUX A; 
#chains in the Genus database with same CATH topology
 1Y5E A;  1IHC A;  2NQV A;  1G8L A;  3OI9 A;  5G2S A;  2F7Y A;  3JSY A;  2NRP A;  1O8O A;  4NWO A;  1UUY A;  1MKZ A;  2NQS A;  5ERU A;  3MCJ A;  2QQ1 A;  2FTS A;  5ERT A;  1UUX A;  4CT8 A;  5ERV A;  4CT9 A;  1JLJ A;  1I6V D;  4TK4 A;  5D6G A;  1YZY A;  1WU2 A;  1UZ5 A;  1O8Q A;  1XI8 A;  3KBQ A;  1R2K A;  2NQU A;  2NQQ A;  1FC5 A;  4TWG A;  2IS8 A;  1T3E A;  3IWT A;  2NRS A;  1G8R A;  4U90 A;  2NRO A;  4XCW A;  1HQM D;  2X3L A;  5ERS A;  2PBQ A;  4U91 A;  1DI6 A;  3TCR A;  3MCI A;  5D8H B;  1O8N A;  4TK3 A;  1EAV A;  5G2R A;  4NWB A;  4CTA B;  2F7W A;  2G4R A;  5ERQ A;  5DMH A;  3K6A A;  3PZY A;  4TK1 A;  3RFQ A;  2NQN A;  4LHB A;  2FU3 A;  1IW7 D;  3DQQ A;  4CTA A;  4PD0 A;  2G2C A;  5ERR A;  1DI7 A;  4UOC A;  2NQK A;  4UUW A;  4PD1 A;  3MCH A;  2NQM A;  2NQR A;  4UUX A; 
#chains in the Genus database with same CATH homology
 1Y5E A;  1IHC A;  2NQV A;  1G8L A;  3OI9 A;  5G2S A;  2F7Y A;  3JSY A;  2NRP A;  1O8O A;  4NWO A;  1UUY A;  1MKZ A;  2NQS A;  5ERU A;  3MCJ A;  2QQ1 A;  2FTS A;  5ERT A;  1UUX A;  4CT8 A;  5ERV A;  4CT9 A;  1JLJ A;  1I6V D;  4TK4 A;  5D6G A;  1WU2 A;  1UZ5 A;  1O8Q A;  1XI8 A;  3KBQ A;  1R2K A;  2NQU A;  2NQQ A;  1FC5 A;  4TWG A;  2IS8 A;  1T3E A;  3IWT A;  2NRS A;  1G8R A;  4U90 A;  2NRO A;  4XCW A;  1HQM D;  2X3L A;  5ERS A;  2PBQ A;  4U91 A;  1DI6 A;  3TCR A;  3MCI A;  5D8H B;  1O8N A;  4TK3 A;  1EAV A;  5G2R A;  4NWB A;  4CTA B;  2F7W A;  2G4R A;  5ERQ A;  3K6A A;  3PZY A;  4TK1 A;  3RFQ A;  2NQN A;  4LHB A;  2FU3 A;  1IW7 D;  4CTA A;  4PD0 A;  2G2C A;  5ERR A;  1DI7 A;  4UOC A;  2NQK A;  4UUW A;  4PD1 A;  3MCH A;  2NQM A;  2NQR A;  4UUX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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