2FTSA

Crystal structure of the glycine receptor-gephyrin complex
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
419
structure length
419
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Deciphering the structural framework of glycine receptor anchoring by gephyrin.
pubmed doi rcsb
molecule tags Structural protein
source organism Rattus norvegicus
molecule keywords gephyrin
total genus 95
structure length 419
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2ftsA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2ftsA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2ftsA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2ftsA02
1O8NA 1UZ5A 2F7YA 1WU2A 3IWTA 2NQSA 2F7WA 1UUYA 2NQKA 2X3LA 3KBQA 4CT8A 2NRPA 2NQUA 2NROA 5ERUA 1G8LA 1FC5A 1G8RA 1Y5EA 2G4RA 3MCJA 3RFQA 4U91A 4TK1A 5ERVA 2PBQA 3PZYA 1IHCA 2NQRA 5ERSA 4U90A 5ERQA 2NRSA 3MCHA 2QQ1A 5G2SA 1EAVA 2NQVA 4CTAB 4UUXA 2FTSA 4TK4A 3K6AA 3MCIA 1T3EA 3TCRA 2FU3A 4PD0A 3OI9A 4LHBA 1R2KA 4TWGA 2G2CA 2NQNA 2NQQA 4TK3A 4CT9A 4CTAA 1UUXA 1MKZA 5ERRA 4UUWA 1O8QA 1XI8A 1DI7A 4NWOA 1JLJA 1O8OA 4UOCA 5ERTA 2NQMA 4XCWA 4PD1A 1DI6A 2IS8A 5G2RA
chains in the Genus database with same CATH superfamily
1O8NA 1YZYA 1UZ5A 2F7YA 1WU2A 3IWTA 2NQSA 2F7WA 1UUYA 2NQKA 2X3LA 3KBQA 4CT8A 2NRPA 2NQUA 2NROA 5ERUA 3DQQA 1G8LA 4NWBA 1FC5A 1G8RA 1Y5EA 2G4RA 3MCJA 3RFQA 1HQMD 4U91A 4TK1A 5ERVA 2PBQA 3PZYA 1IHCA 2NQRA 5ERSA 4U90A 5D8HB 5ERQA 2NRSA 3MCHA 2QQ1A 5G2SA 1EAVA 2NQVA 4CTAB 4UUXA 2FTSA 4TK4A 3K6AA 3MCIA 1T3EA 3TCRA 2FU3A 4PD0A 3OI9A 4LHBA 1R2KA 4TWGA 2G2CA 2NQNA 1IW7D 2NQQA 4TK3A 3JSYA 4CT9A 4CTAA 1UUXA 1MKZA 5ERRA 4UUWA 1O8QA 1XI8A 1DI7A 4NWOA 5D6GA 1JLJA 1O8OA 4UOCA 5ERTA 2NQMA 4XCWA 5DMHA 4PD1A 1DI6A 2IS8A 1I6VD 5G2RA
chains in the Genus database with same CATH topology
1O8NA 1UZ5A 2F7YA 1WU2A 3IWTA 2NQSA 2F7WA 1UUYA 2NQKA 2X3LA 3KBQA 4CT8A 2NRPA 2NQUA 2NROA 5ERUA 1G8LA 4NWBA 1FC5A 1G8RA 1Y5EA 2G4RA 3MCJA 3RFQA 1HQMD 4U91A 4TK1A 5ERVA 2PBQA 3PZYA 1IHCA 2NQRA 5ERSA 4U90A 5D8HB 5ERQA 2NRSA 3MCHA 2QQ1A 5G2SA 1EAVA 2NQVA 4CTAB 4UUXA 2FTSA 4TK4A 3K6AA 3MCIA 1T3EA 3TCRA 2FU3A 4PD0A 3OI9A 4LHBA 1R2KA 4TWGA 2G2CA 2NQNA 1IW7D 2NQQA 4TK3A 3JSYA 4CT9A 4CTAA 1UUXA 1MKZA 5ERRA 4UUWA 1O8QA 1XI8A 1DI7A 4NWOA 5D6GA 1JLJA 1O8OA 4UOCA 5ERTA 2NQMA 4XCWA 4PD1A 1DI6A 2IS8A 1I6VD 5G2RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O8N A;  1UZ5 A;  2F7Y A;  1WU2 A;  3IWT A;  2NQS A;  2F7W A;  1UUY A;  2NQK A;  2X3L A;  3KBQ A;  4CT8 A;  2NRP A;  2NQU A;  2NRO A;  5ERU A;  1G8L A;  1FC5 A;  1G8R A;  1Y5E A;  2G4R A;  3MCJ A;  3RFQ A;  4U91 A;  4TK1 A;  5ERV A;  2PBQ A;  3PZY A;  1IHC A;  2NQR A;  5ERS A;  4U90 A;  5ERQ A;  2NRS A;  3MCH A;  2QQ1 A;  5G2S A;  1EAV A;  2NQV A;  4CTA B;  4UUX A;  2FTS A;  4TK4 A;  3K6A A;  3MCI A;  1T3E A;  3TCR A;  2FU3 A;  4PD0 A;  3OI9 A;  4LHB A;  1R2K A;  4TWG A;  2G2C A;  2NQN A;  2NQQ A;  4TK3 A;  4CT9 A;  4CTA A;  1UUX A;  1MKZ A;  5ERR A;  4UUW A;  1O8Q A;  1XI8 A;  1DI7 A;  4NWO A;  1JLJ A;  1O8O A;  4UOC A;  5ERT A;  2NQM A;  4XCW A;  4PD1 A;  1DI6 A;  2IS8 A;  5G2R A; 
#chains in the Genus database with same CATH topology
 1O8N A;  1YZY A;  1UZ5 A;  2F7Y A;  1WU2 A;  3IWT A;  2NQS A;  2F7W A;  1UUY A;  2NQK A;  2X3L A;  3KBQ A;  4CT8 A;  2NRP A;  2NQU A;  2NRO A;  5ERU A;  3DQQ A;  1G8L A;  4NWB A;  1FC5 A;  1G8R A;  1Y5E A;  2G4R A;  3MCJ A;  3RFQ A;  1HQM D;  4U91 A;  4TK1 A;  5ERV A;  2PBQ A;  3PZY A;  1IHC A;  2NQR A;  5ERS A;  4U90 A;  5D8H B;  5ERQ A;  2NRS A;  3MCH A;  2QQ1 A;  5G2S A;  1EAV A;  2NQV A;  4CTA B;  4UUX A;  2FTS A;  4TK4 A;  3K6A A;  3MCI A;  1T3E A;  3TCR A;  2FU3 A;  4PD0 A;  3OI9 A;  4LHB A;  1R2K A;  4TWG A;  2G2C A;  2NQN A;  1IW7 D;  2NQQ A;  4TK3 A;  3JSY A;  4CT9 A;  4CTA A;  1UUX A;  1MKZ A;  5ERR A;  4UUW A;  1O8Q A;  1XI8 A;  1DI7 A;  4NWO A;  5D6G A;  1JLJ A;  1O8O A;  4UOC A;  5ERT A;  2NQM A;  4XCW A;  5DMH A;  4PD1 A;  1DI6 A;  2IS8 A;  1I6V D;  5G2R A; 
#chains in the Genus database with same CATH homology
 1O8N A;  1UZ5 A;  2F7Y A;  1WU2 A;  3IWT A;  2NQS A;  2F7W A;  1UUY A;  2NQK A;  2X3L A;  3KBQ A;  4CT8 A;  2NRP A;  2NQU A;  2NRO A;  5ERU A;  1G8L A;  4NWB A;  1FC5 A;  1G8R A;  1Y5E A;  2G4R A;  3MCJ A;  3RFQ A;  1HQM D;  4U91 A;  4TK1 A;  5ERV A;  2PBQ A;  3PZY A;  1IHC A;  2NQR A;  5ERS A;  4U90 A;  5D8H B;  5ERQ A;  2NRS A;  3MCH A;  2QQ1 A;  5G2S A;  1EAV A;  2NQV A;  4CTA B;  4UUX A;  2FTS A;  4TK4 A;  3K6A A;  3MCI A;  1T3E A;  3TCR A;  2FU3 A;  4PD0 A;  3OI9 A;  4LHB A;  1R2K A;  4TWG A;  2G2C A;  2NQN A;  1IW7 D;  2NQQ A;  4TK3 A;  3JSY A;  4CT9 A;  4CTA A;  1UUX A;  1MKZ A;  5ERR A;  4UUW A;  1O8Q A;  1XI8 A;  1DI7 A;  4NWO A;  5D6G A;  1JLJ A;  1O8O A;  4UOC A;  5ERT A;  2NQM A;  4XCW A;  4PD1 A;  1DI6 A;  2IS8 A;  1I6V D;  5G2R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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