2FU3A

Crystal structure of gephyrin e-domain
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
419
structure length
405
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Deciphering the structural framework of glycine receptor anchoring by gephyrin.
pubmed doi rcsb
molecule tags Biosynthetic protein/structural protein
source organism Rattus norvegicus
molecule keywords gephyrin
total genus 95
structure length 405
sequence length 419
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2fu3A04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2fu3A03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2fu3A01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2fu3A02
4PD1A 4UUXA 1O8NA 1UZ5A 2NQKA 1O8OA 2NRSA 3MCJA 1R2KA 1FC5A 3PZYA 4CT8A 2NROA 5ERRA 1T3EA 5ERUA 1IHCA 2NQNA 1MKZA 2QQ1A 4UUWA 4TK4A 3K6AA 2F7WA 2NQVA 1G8RA 2IS8A 1Y5EA 1XI8A 2FU3A 1UUYA 4CT9A 2NQMA 4CTAB 4CTAA 3OI9A 5G2RA 2PBQA 1DI7A 1O8QA 3RFQA 5ERQA 5ERSA 3TCRA 1WU2A 1DI6A 4PD0A 2G4RA 4U90A 4TK3A 1EAVA 3MCIA 1G8LA 2X3LA 2NQSA 2NQRA 4TK1A 3KBQA 3MCHA 5G2SA 2NRPA 2F7YA 4LHBA 5ERTA 4UOCA 2G2CA 3IWTA 4TWGA 1UUXA 2NQUA 1JLJA 5ERVA 4NWOA 4XCWA 4U91A 2NQQA 2FTSA
chains in the Genus database with same CATH superfamily
4PD1A 4UUXA 1O8NA 1UZ5A 2NQKA 1O8OA 5DMHA 2NRSA 3MCJA 1R2KA 1FC5A 3PZYA 1I6VD 4CT8A 2NROA 5ERRA 1IW7D 1T3EA 5ERUA 3JSYA 1IHCA 2NQNA 1MKZA 2QQ1A 4UUWA 4TK4A 3K6AA 2F7WA 2NQVA 1G8RA 2IS8A 1Y5EA 1HQMD 1XI8A 2FU3A 1UUYA 4CT9A 2NQMA 4CTAB 4CTAA 3OI9A 5G2RA 2PBQA 1DI7A 1O8QA 3RFQA 5ERQA 5ERSA 3TCRA 1WU2A 1DI6A 4PD0A 2G4RA 4U90A 4NWBA 4TK3A 1EAVA 3MCIA 1YZYA 1G8LA 5D8HB 2X3LA 2NQSA 2NQRA 4TK1A 3KBQA 3MCHA 5G2SA 5D6GA 2NRPA 2F7YA 4LHBA 5ERTA 4UOCA 2G2CA 3IWTA 4TWGA 1UUXA 2NQUA 1JLJA 5ERVA 4NWOA 4XCWA 3DQQA 4U91A 2NQQA 2FTSA
chains in the Genus database with same CATH topology
4PD1A 4UUXA 1O8NA 1UZ5A 2NQKA 1O8OA 2NRSA 3MCJA 1R2KA 1FC5A 3PZYA 1I6VD 4CT8A 2NROA 5ERRA 1IW7D 1T3EA 5ERUA 3JSYA 1IHCA 2NQNA 1MKZA 2QQ1A 4UUWA 4TK4A 3K6AA 2F7WA 2NQVA 1G8RA 2IS8A 1Y5EA 1HQMD 1XI8A 2FU3A 1UUYA 4CT9A 2NQMA 4CTAB 4CTAA 3OI9A 5G2RA 2PBQA 1DI7A 1O8QA 3RFQA 5ERQA 5ERSA 3TCRA 1WU2A 1DI6A 4PD0A 2G4RA 4U90A 4NWBA 4TK3A 1EAVA 3MCIA 1G8LA 5D8HB 2X3LA 2NQSA 2NQRA 4TK1A 3KBQA 3MCHA 5G2SA 5D6GA 2NRPA 2F7YA 4LHBA 5ERTA 4UOCA 2G2CA 3IWTA 4TWGA 1UUXA 2NQUA 1JLJA 5ERVA 4NWOA 4XCWA 4U91A 2NQQA 2FTSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PD1 A;  4UUX A;  1O8N A;  1UZ5 A;  2NQK A;  1O8O A;  2NRS A;  3MCJ A;  1R2K A;  1FC5 A;  3PZY A;  4CT8 A;  2NRO A;  5ERR A;  1T3E A;  5ERU A;  1IHC A;  2NQN A;  1MKZ A;  2QQ1 A;  4UUW A;  4TK4 A;  3K6A A;  2F7W A;  2NQV A;  1G8R A;  2IS8 A;  1Y5E A;  1XI8 A;  2FU3 A;  1UUY A;  4CT9 A;  2NQM A;  4CTA B;  4CTA A;  3OI9 A;  5G2R A;  2PBQ A;  1DI7 A;  1O8Q A;  3RFQ A;  5ERQ A;  5ERS A;  3TCR A;  1WU2 A;  1DI6 A;  4PD0 A;  2G4R A;  4U90 A;  4TK3 A;  1EAV A;  3MCI A;  1G8L A;  2X3L A;  2NQS A;  2NQR A;  4TK1 A;  3KBQ A;  3MCH A;  5G2S A;  2NRP A;  2F7Y A;  4LHB A;  5ERT A;  4UOC A;  2G2C A;  3IWT A;  4TWG A;  1UUX A;  2NQU A;  1JLJ A;  5ERV A;  4NWO A;  4XCW A;  4U91 A;  2NQQ A;  2FTS A; 
#chains in the Genus database with same CATH topology
 4PD1 A;  4UUX A;  1O8N A;  1UZ5 A;  2NQK A;  1O8O A;  5DMH A;  2NRS A;  3MCJ A;  1R2K A;  1FC5 A;  3PZY A;  1I6V D;  4CT8 A;  2NRO A;  5ERR A;  1IW7 D;  1T3E A;  5ERU A;  3JSY A;  1IHC A;  2NQN A;  1MKZ A;  2QQ1 A;  4UUW A;  4TK4 A;  3K6A A;  2F7W A;  2NQV A;  1G8R A;  2IS8 A;  1Y5E A;  1HQM D;  1XI8 A;  2FU3 A;  1UUY A;  4CT9 A;  2NQM A;  4CTA B;  4CTA A;  3OI9 A;  5G2R A;  2PBQ A;  1DI7 A;  1O8Q A;  3RFQ A;  5ERQ A;  5ERS A;  3TCR A;  1WU2 A;  1DI6 A;  4PD0 A;  2G4R A;  4U90 A;  4NWB A;  4TK3 A;  1EAV A;  3MCI A;  1YZY A;  1G8L A;  5D8H B;  2X3L A;  2NQS A;  2NQR A;  4TK1 A;  3KBQ A;  3MCH A;  5G2S A;  5D6G A;  2NRP A;  2F7Y A;  4LHB A;  5ERT A;  4UOC A;  2G2C A;  3IWT A;  4TWG A;  1UUX A;  2NQU A;  1JLJ A;  5ERV A;  4NWO A;  4XCW A;  3DQQ A;  4U91 A;  2NQQ A;  2FTS A; 
#chains in the Genus database with same CATH homology
 4PD1 A;  4UUX A;  1O8N A;  1UZ5 A;  2NQK A;  1O8O A;  2NRS A;  3MCJ A;  1R2K A;  1FC5 A;  3PZY A;  1I6V D;  4CT8 A;  2NRO A;  5ERR A;  1IW7 D;  1T3E A;  5ERU A;  3JSY A;  1IHC A;  2NQN A;  1MKZ A;  2QQ1 A;  4UUW A;  4TK4 A;  3K6A A;  2F7W A;  2NQV A;  1G8R A;  2IS8 A;  1Y5E A;  1HQM D;  1XI8 A;  2FU3 A;  1UUY A;  4CT9 A;  2NQM A;  4CTA B;  4CTA A;  3OI9 A;  5G2R A;  2PBQ A;  1DI7 A;  1O8Q A;  3RFQ A;  5ERQ A;  5ERS A;  3TCR A;  1WU2 A;  1DI6 A;  4PD0 A;  2G4R A;  4U90 A;  4NWB A;  4TK3 A;  1EAV A;  3MCI A;  1G8L A;  5D8H B;  2X3L A;  2NQS A;  2NQR A;  4TK1 A;  3KBQ A;  3MCH A;  5G2S A;  5D6G A;  2NRP A;  2F7Y A;  4LHB A;  5ERT A;  4UOC A;  2G2C A;  3IWT A;  4TWG A;  1UUX A;  2NQU A;  1JLJ A;  5ERV A;  4NWO A;  4XCW A;  4U91 A;  2NQQ A;  2FTS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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