2H9GR

Crystal structure of phage derived fab bdf1 with human death receptor 5 (dr5)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
108
structure length
108
Chain Sequence
SSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists.
pubmed doi rcsb
molecule keywords Fab BdF1, light chain
molecule tags Immune system/apoptosis
source organism Homo sapiens
total genus 15
structure length 108
sequence length 108
chains with identical sequence S
ec nomenclature
pdb deposition date 2006-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 2h9gR01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 2h9gR02
3MHDD 4I9XC 3U3SA 1SG1X 3ME2R 4N90R 4FHQA 4OD2S 3U3VA 2X10A 4YN0A 4M4PA 3U3TA 1DU3A 3QD6R 2UWIA 4KGGC 2HEVR 1D4VA 3FL7A 3K51B 3WVTA 2HEYR 3IJ2X 3X3FA 2H9GR 4KGQC 3TJEF 1JMAB 4M4RA 2AW2B 5L36B 3MI8D 3U3PA 1FT4A 1ZA3R 4BK5A 5DMJA 1D0GR 4J6GC 3QO4A 4BK4A 1EXTA 4MSVB 3MBWA 5CIRE 4GIQR 4E4DR 4RSUD 3ALQR 3THMF 5IHLA 1NCFA 3BUKC 1TNRR 4MXWR 3U3QA 3QBQB 5BNQR 3ME4A 3URFZ
chains in the Genus database with same CATH superfamily
2E4UA 3MHDD 4I9XC 3U3SA 1SG1X 3ME2R 4N90R 4FHQA 4OD2S 3U3VA 2X10A 4YN0A 4M4PA 3U3TA 1DU3A 3QD6R 2UWIA 4KGGC 2HEVR 1D4VA 2E4XA 3FL7A 3K51B 3WVTA 2HEYR 3IJ2X 3X3FA 2H9GR 4KGQC 3TJEF 1JMAB 4M4RA 2AW2B 5L36B 3MI8D 3U3PA 1FT4A 1ZA3R 4BK5A 2E4YA 5DMJA 1D0GR 4J6GC 3QO4A 4BK4A 1EXTA 4MSVB 3MBWA 5CIRE 2E4VA 4GIQR 4E4DR 4RSUD 5BNQR 3ALQR 3THMF 2QR6A 5IHLA 1NCFA 3BUKC 1TNRR 4MXWR 3U3QA 3QBQB 2E4WA 3ME4A 3URFZ
chains in the Genus database with same CATH topology
3MHDD 4I9XC 3U3SA 1SG1X 3ME2R 4N90R 4FHQA 4OD2S 3U3VA 2X10A 4YN0A 4M4PA 3U3TA 1DU3A 3QD6R 2UWIA 4KGGC 2HEVR 1D4VA 3FL7A 3K51B 3WVTA 2HEYR 3IJ2X 3X3FA 2H9GR 4KGQC 3TJEF 1JMAB 4M4RA 2AW2B 5L36B 3MI8D 3U3PA 1FT4A 1ZA3R 4BK5A 5DMJA 1D0GR 4J6GC 3QO4A 4BK4A 1EXTA 4MSVB 3MBWA 5CIRE 4GIQR 4E4DR 4RSUD 3ALQR 3THMF 5IHLA 1NCFA 3BUKC 1TNRR 4MXWR 3U3QA 3QBQB 5BNQR 3ME4A 3URFZ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MHD D;  4I9X C;  3U3S A;  1SG1 X;  3ME2 R;  4N90 R;  4FHQ A;  4OD2 S;  3U3V A;  2X10 A;  4YN0 A;  4M4P A;  3U3T A;  1DU3 A;  3QD6 R;  2UWI A;  4KGG C;  2HEV R;  1D4V A;  3FL7 A;  3K51 B;  3WVT A;  2HEY R;  3IJ2 X;  3X3F A;  2H9G R;  4KGQ C;  3TJE F;  1JMA B;  4M4R A;  2AW2 B;  5L36 B;  3MI8 D;  3U3P A;  1FT4 A;  1ZA3 R;  4BK5 A;  5DMJ A;  1D0G R;  4J6G C;  3QO4 A;  4BK4 A;  1EXT A;  4MSV B;  3MBW A;  5CIR E;  4GIQ R;  4E4D R;  4RSU D;  3ALQ R;  3THM F;  5IHL A;  1NCF A;  3BUK C;  1TNR R;  4MXW R;  3U3Q A;  3QBQ B;  5BNQ R;  3ME4 A;  3URF Z; 
#chains in the Genus database with same CATH topology
 2E4U A;  3MHD D;  4I9X C;  3U3S A;  1SG1 X;  3ME2 R;  4N90 R;  4FHQ A;  4OD2 S;  3U3V A;  2X10 A;  4YN0 A;  4M4P A;  3U3T A;  1DU3 A;  3QD6 R;  2UWI A;  4KGG C;  2HEV R;  1D4V A;  2E4X A;  3FL7 A;  3K51 B;  3WVT A;  2HEY R;  3IJ2 X;  3X3F A;  2H9G R;  4KGQ C;  3TJE F;  1JMA B;  4M4R A;  2AW2 B;  5L36 B;  3MI8 D;  3U3P A;  1FT4 A;  1ZA3 R;  4BK5 A;  2E4Y A;  5DMJ A;  1D0G R;  4J6G C;  3QO4 A;  4BK4 A;  1EXT A;  4MSV B;  3MBW A;  5CIR E;  2E4V A;  4GIQ R;  4E4D R;  4RSU D;  5BNQ R;  3ALQ R;  3THM F;  2QR6 A;  5IHL A;  1NCF A;  3BUK C;  1TNR R;  4MXW R;  3U3Q A;  3QBQ B;  2E4W A;  3ME4 A;  3URF Z; 
#chains in the Genus database with same CATH homology
 3MHD D;  4I9X C;  3U3S A;  1SG1 X;  3ME2 R;  4N90 R;  4FHQ A;  4OD2 S;  3U3V A;  2X10 A;  4YN0 A;  4M4P A;  3U3T A;  1DU3 A;  3QD6 R;  2UWI A;  4KGG C;  2HEV R;  1D4V A;  3FL7 A;  3K51 B;  3WVT A;  2HEY R;  3IJ2 X;  3X3F A;  2H9G R;  4KGQ C;  3TJE F;  1JMA B;  4M4R A;  2AW2 B;  5L36 B;  3MI8 D;  3U3P A;  1FT4 A;  1ZA3 R;  4BK5 A;  5DMJ A;  1D0G R;  4J6G C;  3QO4 A;  4BK4 A;  1EXT A;  4MSV B;  3MBW A;  5CIR E;  4GIQ R;  4E4D R;  4RSU D;  3ALQ R;  3THM F;  5IHL A;  1NCF A;  3BUK C;  1TNR R;  4MXW R;  3U3Q A;  3QBQ B;  5BNQ R;  3ME4 A;  3URF Z; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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