2H9GR

Crystal structure of phage derived fab bdf1 with human death receptor 5 (dr5)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
108
structure length
108
Chain Sequence
SSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system/apoptosis
source organism Homo sapiens
publication title Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists.
pubmed doi rcsb
molecule keywords Fab BdF1, light chain
total genus 15
structure length 108
sequence length 108
chains with identical sequence S
ec nomenclature
pdb deposition date 2006-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 2h9gR01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 2h9gR02
1JMAB 3ALQR 4MXWR 3ME4A 3U3QA 3U3PA 5L36B 3X3FA 1D4VA 5DMJA 4E4DR 1SG1X 1TNRR 4MSVB 5BNQR 3U3TA 4KGGC 3IJ2X 3URFZ 5IHLA 4I9XC 3QD6R 4GIQR 2HEYR 3THMF 1NCFA 2HEVR 1EXTA 4BK5A 4KGQC 1DU3A 4YN0A 4N90R 2H9GR 3MBWA 1FT4A 3FL7A 3ME2R 4FHQA 3WVTA 4J6GC 3U3SA 2AW2B 4OD2S 3BUKC 3QBQB 1ZA3R 3MI8D 3QO4A 1D0GR 3MHDD 4BK4A 5CIRE 4RSUD 3U3VA 2UWIA 3TJEF 4M4RA 2X10A 3K51B 4M4PA
chains in the Genus database with same CATH superfamily
1JMAB 3ALQR 4MXWR 3ME4A 3U3QA 3U3PA 2E4WA 2E4VA 3X3FA 5L36B 1D4VA 5DMJA 4E4DR 1SG1X 1TNRR 4MSVB 5BNQR 3U3TA 4KGGC 2E4YA 3IJ2X 3URFZ 5IHLA 4I9XC 3QD6R 4GIQR 2E4UA 2HEYR 3THMF 1NCFA 2HEVR 1EXTA 4BK5A 4KGQC 1DU3A 4YN0A 4N90R 2H9GR 3MBWA 1FT4A 3FL7A 3ME2R 4FHQA 3WVTA 4J6GC 3U3SA 2AW2B 4OD2S 3BUKC 2QR6A 1ZA3R 3MI8D 3QBQB 3QO4A 1D0GR 3MHDD 4BK4A 5CIRE 4RSUD 2E4XA 3U3VA 2UWIA 3TJEF 4M4RA 2X10A 3K51B 4M4PA
chains in the Genus database with same CATH topology
1JMAB 3ALQR 4MXWR 3ME4A 3U3QA 3U3PA 5L36B 3X3FA 1D4VA 5DMJA 4E4DR 1SG1X 1TNRR 4MSVB 5BNQR 3U3TA 4KGGC 3IJ2X 3URFZ 5IHLA 4I9XC 3QD6R 4GIQR 2HEYR 3THMF 1NCFA 2HEVR 1EXTA 4BK5A 4KGQC 1DU3A 4YN0A 4N90R 2H9GR 3MBWA 1FT4A 3FL7A 3ME2R 4FHQA 3WVTA 4J6GC 3U3SA 2AW2B 4OD2S 3BUKC 3QBQB 1ZA3R 3MI8D 3QO4A 1D0GR 3MHDD 4BK4A 5CIRE 4RSUD 3U3VA 2UWIA 3TJEF 4M4RA 2X10A 3K51B 4M4PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JMA B;  3ALQ R;  4MXW R;  3ME4 A;  3U3Q A;  3U3P A;  5L36 B;  3X3F A;  1D4V A;  5DMJ A;  4E4D R;  1SG1 X;  1TNR R;  4MSV B;  5BNQ R;  3U3T A;  4KGG C;  3IJ2 X;  3URF Z;  5IHL A;  4I9X C;  3QD6 R;  4GIQ R;  2HEY R;  3THM F;  1NCF A;  2HEV R;  1EXT A;  4BK5 A;  4KGQ C;  1DU3 A;  4YN0 A;  4N90 R;  2H9G R;  3MBW A;  1FT4 A;  3FL7 A;  3ME2 R;  4FHQ A;  3WVT A;  4J6G C;  3U3S A;  2AW2 B;  4OD2 S;  3BUK C;  3QBQ B;  1ZA3 R;  3MI8 D;  3QO4 A;  1D0G R;  3MHD D;  4BK4 A;  5CIR E;  4RSU D;  3U3V A;  2UWI A;  3TJE F;  4M4R A;  2X10 A;  3K51 B;  4M4P A; 
#chains in the Genus database with same CATH topology
 1JMA B;  3ALQ R;  4MXW R;  3ME4 A;  3U3Q A;  3U3P A;  2E4W A;  2E4V A;  3X3F A;  5L36 B;  1D4V A;  5DMJ A;  4E4D R;  1SG1 X;  1TNR R;  4MSV B;  5BNQ R;  3U3T A;  4KGG C;  2E4Y A;  3IJ2 X;  3URF Z;  5IHL A;  4I9X C;  3QD6 R;  4GIQ R;  2E4U A;  2HEY R;  3THM F;  1NCF A;  2HEV R;  1EXT A;  4BK5 A;  4KGQ C;  1DU3 A;  4YN0 A;  4N90 R;  2H9G R;  3MBW A;  1FT4 A;  3FL7 A;  3ME2 R;  4FHQ A;  3WVT A;  4J6G C;  3U3S A;  2AW2 B;  4OD2 S;  3BUK C;  2QR6 A;  1ZA3 R;  3MI8 D;  3QBQ B;  3QO4 A;  1D0G R;  3MHD D;  4BK4 A;  5CIR E;  4RSU D;  2E4X A;  3U3V A;  2UWI A;  3TJE F;  4M4R A;  2X10 A;  3K51 B;  4M4P A; 
#chains in the Genus database with same CATH homology
 1JMA B;  3ALQ R;  4MXW R;  3ME4 A;  3U3Q A;  3U3P A;  5L36 B;  3X3F A;  1D4V A;  5DMJ A;  4E4D R;  1SG1 X;  1TNR R;  4MSV B;  5BNQ R;  3U3T A;  4KGG C;  3IJ2 X;  3URF Z;  5IHL A;  4I9X C;  3QD6 R;  4GIQ R;  2HEY R;  3THM F;  1NCF A;  2HEV R;  1EXT A;  4BK5 A;  4KGQ C;  1DU3 A;  4YN0 A;  4N90 R;  2H9G R;  3MBW A;  1FT4 A;  3FL7 A;  3ME2 R;  4FHQ A;  3WVT A;  4J6G C;  3U3S A;  2AW2 B;  4OD2 S;  3BUK C;  3QBQ B;  1ZA3 R;  3MI8 D;  3QO4 A;  1D0G R;  3MHD D;  4BK4 A;  5CIR E;  4RSU D;  3U3V A;  2UWI A;  3TJE F;  4M4R A;  2X10 A;  3K51 B;  4M4P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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