2NQNA

Moea t100w
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
405
structure length
405
Chain Sequence
GLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMWGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Escherichia coli
molecule keywords Molybdopterin biosynthesis protein moeA
total genus 109
structure length 405
sequence length 405
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2nqnA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2nqnA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2nqnA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2nqnA02
3OI9A 2QQ1A 2F7YA 1XI8A 1MKZA 5G2SA 3RFQA 3MCHA 4PD1A 1EAVA 4TK4A 5ERVA 5ERTA 4CTAB 2NQNA 2NQRA 1DI7A 2PBQA 1DI6A 1R2KA 1IHCA 3MCIA 1UUYA 1Y5EA 1UUXA 4U90A 1WU2A 2NQMA 1G8RA 5ERSA 4TWGA 5ERUA 4XCWA 2NQQA 1JLJA 2NRSA 2NQUA 4UUWA 2FTSA 3MCJA 2NQKA 4CT8A 3TCRA 3PZYA 1T3EA 4TK1A 2FU3A 1O8QA 2X3LA 3K6AA 5G2RA 2G2CA 4CT9A 2G4RA 2NROA 4U91A 5ERQA 4NWOA 5ERRA 1UZ5A 3IWTA 4PD0A 4LHBA 4CTAA 1O8OA 1FC5A 2NQSA 4TK3A 2NRPA 1O8NA 4UUXA 4UOCA 2F7WA 2IS8A 2NQVA 3KBQA 1G8LA
chains in the Genus database with same CATH superfamily
3OI9A 2QQ1A 2F7YA 1XI8A 1MKZA 5G2SA 3RFQA 3MCHA 4NWBA 4PD1A 1EAVA 4TK4A 5ERVA 5ERTA 4CTAB 2NQNA 2NQRA 1DI7A 1IW7D 2PBQA 1DI6A 5DMHA 1R2KA 1IHCA 3MCIA 1UUYA 1Y5EA 1UUXA 4U90A 1I6VD 1HQMD 1WU2A 2NQMA 1G8RA 5ERSA 4TWGA 5ERUA 4XCWA 2NQQA 1YZYA 1JLJA 2NRSA 2NQUA 4UUWA 2FTSA 3MCJA 2NQKA 4CT8A 5D8HB 3TCRA 3PZYA 1T3EA 4TK1A 2FU3A 1O8QA 2X3LA 3K6AA 3DQQA 5G2RA 2G2CA 4CT9A 2G4RA 2NROA 4U91A 5ERQA 4NWOA 5ERRA 1UZ5A 3IWTA 4PD0A 4LHBA 4CTAA 1O8OA 1FC5A 5D6GA 3JSYA 2NQSA 4TK3A 2NRPA 1O8NA 4UUXA 4UOCA 2F7WA 2IS8A 2NQVA 3KBQA 1G8LA
chains in the Genus database with same CATH topology
3OI9A 2QQ1A 2F7YA 1XI8A 1MKZA 5G2SA 3RFQA 3MCHA 4NWBA 4PD1A 1EAVA 4TK4A 5ERVA 5ERTA 4CTAB 2NQNA 2NQRA 1DI7A 1IW7D 2PBQA 1DI6A 1R2KA 1IHCA 3MCIA 1UUYA 1Y5EA 1UUXA 4U90A 1I6VD 1HQMD 1WU2A 2NQMA 1G8RA 5ERSA 4TWGA 5ERUA 4XCWA 2NQQA 1JLJA 2NRSA 2NQUA 4UUWA 2FTSA 3MCJA 2NQKA 4CT8A 5D8HB 3TCRA 3PZYA 1T3EA 4TK1A 2FU3A 1O8QA 2X3LA 3K6AA 5G2RA 2G2CA 4CT9A 2G4RA 2NROA 4U91A 5ERQA 4NWOA 5ERRA 1UZ5A 3IWTA 4PD0A 4LHBA 4CTAA 1O8OA 1FC5A 5D6GA 3JSYA 2NQSA 4TK3A 2NRPA 1O8NA 4UUXA 4UOCA 2F7WA 2IS8A 2NQVA 3KBQA 1G8LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OI9 A;  2QQ1 A;  2F7Y A;  1XI8 A;  1MKZ A;  5G2S A;  3RFQ A;  3MCH A;  4PD1 A;  1EAV A;  4TK4 A;  5ERV A;  5ERT A;  4CTA B;  2NQN A;  2NQR A;  1DI7 A;  2PBQ A;  1DI6 A;  1R2K A;  1IHC A;  3MCI A;  1UUY A;  1Y5E A;  1UUX A;  4U90 A;  1WU2 A;  2NQM A;  1G8R A;  5ERS A;  4TWG A;  5ERU A;  4XCW A;  2NQQ A;  1JLJ A;  2NRS A;  2NQU A;  4UUW A;  2FTS A;  3MCJ A;  2NQK A;  4CT8 A;  3TCR A;  3PZY A;  1T3E A;  4TK1 A;  2FU3 A;  1O8Q A;  2X3L A;  3K6A A;  5G2R A;  2G2C A;  4CT9 A;  2G4R A;  2NRO A;  4U91 A;  5ERQ A;  4NWO A;  5ERR A;  1UZ5 A;  3IWT A;  4PD0 A;  4LHB A;  4CTA A;  1O8O A;  1FC5 A;  2NQS A;  4TK3 A;  2NRP A;  1O8N A;  4UUX A;  4UOC A;  2F7W A;  2IS8 A;  2NQV A;  3KBQ A;  1G8L A; 
#chains in the Genus database with same CATH topology
 3OI9 A;  2QQ1 A;  2F7Y A;  1XI8 A;  1MKZ A;  5G2S A;  3RFQ A;  3MCH A;  4NWB A;  4PD1 A;  1EAV A;  4TK4 A;  5ERV A;  5ERT A;  4CTA B;  2NQN A;  2NQR A;  1DI7 A;  1IW7 D;  2PBQ A;  1DI6 A;  5DMH A;  1R2K A;  1IHC A;  3MCI A;  1UUY A;  1Y5E A;  1UUX A;  4U90 A;  1I6V D;  1HQM D;  1WU2 A;  2NQM A;  1G8R A;  5ERS A;  4TWG A;  5ERU A;  4XCW A;  2NQQ A;  1YZY A;  1JLJ A;  2NRS A;  2NQU A;  4UUW A;  2FTS A;  3MCJ A;  2NQK A;  4CT8 A;  5D8H B;  3TCR A;  3PZY A;  1T3E A;  4TK1 A;  2FU3 A;  1O8Q A;  2X3L A;  3K6A A;  3DQQ A;  5G2R A;  2G2C A;  4CT9 A;  2G4R A;  2NRO A;  4U91 A;  5ERQ A;  4NWO A;  5ERR A;  1UZ5 A;  3IWT A;  4PD0 A;  4LHB A;  4CTA A;  1O8O A;  1FC5 A;  5D6G A;  3JSY A;  2NQS A;  4TK3 A;  2NRP A;  1O8N A;  4UUX A;  4UOC A;  2F7W A;  2IS8 A;  2NQV A;  3KBQ A;  1G8L A; 
#chains in the Genus database with same CATH homology
 3OI9 A;  2QQ1 A;  2F7Y A;  1XI8 A;  1MKZ A;  5G2S A;  3RFQ A;  3MCH A;  4NWB A;  4PD1 A;  1EAV A;  4TK4 A;  5ERV A;  5ERT A;  4CTA B;  2NQN A;  2NQR A;  1DI7 A;  1IW7 D;  2PBQ A;  1DI6 A;  1R2K A;  1IHC A;  3MCI A;  1UUY A;  1Y5E A;  1UUX A;  4U90 A;  1I6V D;  1HQM D;  1WU2 A;  2NQM A;  1G8R A;  5ERS A;  4TWG A;  5ERU A;  4XCW A;  2NQQ A;  1JLJ A;  2NRS A;  2NQU A;  4UUW A;  2FTS A;  3MCJ A;  2NQK A;  4CT8 A;  5D8H B;  3TCR A;  3PZY A;  1T3E A;  4TK1 A;  2FU3 A;  1O8Q A;  2X3L A;  3K6A A;  5G2R A;  2G2C A;  4CT9 A;  2G4R A;  2NRO A;  4U91 A;  5ERQ A;  4NWO A;  5ERR A;  1UZ5 A;  3IWT A;  4PD0 A;  4LHB A;  4CTA A;  1O8O A;  1FC5 A;  5D6G A;  3JSY A;  2NQS A;  4TK3 A;  2NRP A;  1O8N A;  4UUX A;  4UOC A;  2F7W A;  2IS8 A;  2NQV A;  3KBQ A;  1G8L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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