2NQQA

Moea r137q
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
403
structure length
403
Chain Sequence
LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIQRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Escherichia coli
molecule keywords Molybdopterin biosynthesis protein moeA
total genus 107
structure length 403
sequence length 403
chains with identical sequence B, C, D
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2nqqA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2nqqA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2nqqA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2nqqA02
1JLJA 1WU2A 2G2CA 4PD0A 1O8OA 4NWOA 5ERSA 4LHBA 2NQMA 2NQQA 3MCIA 1EAVA 1O8QA 2F7WA 4UOCA 4CT9A 4CTAB 1MKZA 2NQRA 3RFQA 2FU3A 3TCRA 1XI8A 5G2RA 1FC5A 2F7YA 3KBQA 1DI7A 1UUYA 3OI9A 2IS8A 2NQSA 3MCJA 2NRSA 3K6AA 2QQ1A 5ERQA 5G2SA 1DI6A 1R2KA 4UUXA 4PD1A 2NQVA 4UUWA 1T3EA 2NRPA 2X3LA 1IHCA 1UUXA 5ERRA 2NQKA 2G4RA 4CTAA 1O8NA 4U91A 5ERVA 5ERUA 5ERTA 4TWGA 4U90A 3MCHA 4CT8A 4TK3A 2FTSA 3IWTA 2PBQA 4XCWA 2NROA 2NQUA 4TK4A 1UZ5A 1G8LA 1Y5EA 2NQNA 4TK1A 3PZYA 1G8RA
chains in the Genus database with same CATH superfamily
1JLJA 1WU2A 1IW7D 2G2CA 4PD0A 1O8OA 4NWOA 5ERSA 4LHBA 2NQMA 2NQQA 3MCIA 1EAVA 1O8QA 1I6VD 2F7WA 4UOCA 4CT9A 4CTAB 1MKZA 2NQRA 3RFQA 2FU3A 3TCRA 1XI8A 5G2RA 1FC5A 2F7YA 3KBQA 1DI7A 1UUYA 3OI9A 2IS8A 2NQSA 3MCJA 2NRSA 3K6AA 2QQ1A 5ERQA 5G2SA 1DI6A 1HQMD 1R2KA 4UUXA 4PD1A 5D6GA 2NQVA 4UUWA 1T3EA 2NRPA 2X3LA 5D8HB 1IHCA 1UUXA 5DMHA 5ERRA 2NQKA 2G4RA 4CTAA 1O8NA 4U91A 5ERVA 4NWBA 5ERUA 5ERTA 4TWGA 4U90A 3MCHA 4CT8A 4TK3A 2FTSA 3IWTA 3JSYA 2PBQA 4XCWA 2NROA 2NQUA 3DQQA 4TK4A 1YZYA 1UZ5A 1G8LA 1Y5EA 2NQNA 4TK1A 3PZYA 1G8RA
chains in the Genus database with same CATH topology
1JLJA 1WU2A 1IW7D 2G2CA 4PD0A 1O8OA 4NWOA 5ERSA 4LHBA 2NQMA 2NQQA 3MCIA 1EAVA 1O8QA 1I6VD 2F7WA 4UOCA 4CT9A 4CTAB 1MKZA 2NQRA 3RFQA 2FU3A 3TCRA 1XI8A 5G2RA 1FC5A 2F7YA 3KBQA 1DI7A 1UUYA 3OI9A 2IS8A 2NQSA 3MCJA 2NRSA 3K6AA 2QQ1A 5ERQA 5G2SA 1DI6A 1HQMD 1R2KA 4UUXA 4PD1A 5D6GA 2NQVA 4UUWA 1T3EA 2NRPA 2X3LA 5D8HB 1IHCA 1UUXA 5ERRA 2NQKA 2G4RA 4CTAA 1O8NA 4U91A 5ERVA 4NWBA 5ERUA 5ERTA 4TWGA 4U90A 3MCHA 4CT8A 4TK3A 2FTSA 3IWTA 3JSYA 2PBQA 4XCWA 2NROA 2NQUA 4TK4A 1UZ5A 1G8LA 1Y5EA 2NQNA 4TK1A 3PZYA 1G8RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JLJ A;  1WU2 A;  2G2C A;  4PD0 A;  1O8O A;  4NWO A;  5ERS A;  4LHB A;  2NQM A;  2NQQ A;  3MCI A;  1EAV A;  1O8Q A;  2F7W A;  4UOC A;  4CT9 A;  4CTA B;  1MKZ A;  2NQR A;  3RFQ A;  2FU3 A;  3TCR A;  1XI8 A;  5G2R A;  1FC5 A;  2F7Y A;  3KBQ A;  1DI7 A;  1UUY A;  3OI9 A;  2IS8 A;  2NQS A;  3MCJ A;  2NRS A;  3K6A A;  2QQ1 A;  5ERQ A;  5G2S A;  1DI6 A;  1R2K A;  4UUX A;  4PD1 A;  2NQV A;  4UUW A;  1T3E A;  2NRP A;  2X3L A;  1IHC A;  1UUX A;  5ERR A;  2NQK A;  2G4R A;  4CTA A;  1O8N A;  4U91 A;  5ERV A;  5ERU A;  5ERT A;  4TWG A;  4U90 A;  3MCH A;  4CT8 A;  4TK3 A;  2FTS A;  3IWT A;  2PBQ A;  4XCW A;  2NRO A;  2NQU A;  4TK4 A;  1UZ5 A;  1G8L A;  1Y5E A;  2NQN A;  4TK1 A;  3PZY A;  1G8R A; 
#chains in the Genus database with same CATH topology
 1JLJ A;  1WU2 A;  1IW7 D;  2G2C A;  4PD0 A;  1O8O A;  4NWO A;  5ERS A;  4LHB A;  2NQM A;  2NQQ A;  3MCI A;  1EAV A;  1O8Q A;  1I6V D;  2F7W A;  4UOC A;  4CT9 A;  4CTA B;  1MKZ A;  2NQR A;  3RFQ A;  2FU3 A;  3TCR A;  1XI8 A;  5G2R A;  1FC5 A;  2F7Y A;  3KBQ A;  1DI7 A;  1UUY A;  3OI9 A;  2IS8 A;  2NQS A;  3MCJ A;  2NRS A;  3K6A A;  2QQ1 A;  5ERQ A;  5G2S A;  1DI6 A;  1HQM D;  1R2K A;  4UUX A;  4PD1 A;  5D6G A;  2NQV A;  4UUW A;  1T3E A;  2NRP A;  2X3L A;  5D8H B;  1IHC A;  1UUX A;  5DMH A;  5ERR A;  2NQK A;  2G4R A;  4CTA A;  1O8N A;  4U91 A;  5ERV A;  4NWB A;  5ERU A;  5ERT A;  4TWG A;  4U90 A;  3MCH A;  4CT8 A;  4TK3 A;  2FTS A;  3IWT A;  3JSY A;  2PBQ A;  4XCW A;  2NRO A;  2NQU A;  3DQQ A;  4TK4 A;  1YZY A;  1UZ5 A;  1G8L A;  1Y5E A;  2NQN A;  4TK1 A;  3PZY A;  1G8R A; 
#chains in the Genus database with same CATH homology
 1JLJ A;  1WU2 A;  1IW7 D;  2G2C A;  4PD0 A;  1O8O A;  4NWO A;  5ERS A;  4LHB A;  2NQM A;  2NQQ A;  3MCI A;  1EAV A;  1O8Q A;  1I6V D;  2F7W A;  4UOC A;  4CT9 A;  4CTA B;  1MKZ A;  2NQR A;  3RFQ A;  2FU3 A;  3TCR A;  1XI8 A;  5G2R A;  1FC5 A;  2F7Y A;  3KBQ A;  1DI7 A;  1UUY A;  3OI9 A;  2IS8 A;  2NQS A;  3MCJ A;  2NRS A;  3K6A A;  2QQ1 A;  5ERQ A;  5G2S A;  1DI6 A;  1HQM D;  1R2K A;  4UUX A;  4PD1 A;  5D6G A;  2NQV A;  4UUW A;  1T3E A;  2NRP A;  2X3L A;  5D8H B;  1IHC A;  1UUX A;  5ERR A;  2NQK A;  2G4R A;  4CTA A;  1O8N A;  4U91 A;  5ERV A;  4NWB A;  5ERU A;  5ERT A;  4TWG A;  4U90 A;  3MCH A;  4CT8 A;  4TK3 A;  2FTS A;  3IWT A;  3JSY A;  2PBQ A;  4XCW A;  2NRO A;  2NQU A;  4TK4 A;  1UZ5 A;  1G8L A;  1Y5E A;  2NQN A;  4TK1 A;  3PZY A;  1G8R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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