2NQRA

Moea d142n
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
404
structure length
404
Chain Sequence
LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGENISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Escherichia coli
molecule keywords Molybdopterin biosynthesis protein moeA
total genus 108
structure length 404
sequence length 404
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2nqrA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2nqrA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2nqrA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2nqrA02
1WU2A 1DI6A 4PD0A 1G8RA 4TK3A 4CTAB 5ERQA 1JLJA 1Y5EA 1XI8A 4U90A 2NQRA 4TWGA 3MCIA 1O8NA 1R2KA 1G8LA 4PD1A 4UOCA 2FTSA 5ERRA 1UUYA 4TK4A 2NQUA 4UUXA 2NQVA 3K6AA 3TCRA 1O8OA 3IWTA 4NWOA 2NRSA 2FU3A 5ERVA 1UUXA 5ERTA 4CT9A 5ERSA 3MCJA 3OI9A 4CT8A 1O8QA 1UZ5A 5G2RA 1IHCA 2NQKA 1T3EA 1EAVA 2X3LA 4LHBA 1MKZA 4CTAA 2PBQA 3KBQA 2IS8A 2NQNA 2F7WA 4UUWA 2QQ1A 2NROA 1FC5A 5G2SA 4XCWA 2NQSA 3RFQA 2G4RA 2NQQA 2F7YA 3PZYA 2G2CA 4TK1A 2NQMA 4U91A 5ERUA 3MCHA 1DI7A 2NRPA
chains in the Genus database with same CATH superfamily
1WU2A 1DI6A 4PD0A 1G8RA 4TK3A 4CTAB 5ERQA 1JLJA 1Y5EA 1XI8A 4U90A 2NQRA 4TWGA 3MCIA 1O8NA 1R2KA 1G8LA 4PD1A 4UOCA 2FTSA 5ERRA 1UUYA 4TK4A 2NQUA 1I6VD 4UUXA 2NQVA 3K6AA 3TCRA 1O8OA 3IWTA 4NWOA 3DQQA 2NRSA 2FU3A 5ERVA 1HQMD 4NWBA 1UUXA 5ERTA 3JSYA 4CT9A 5ERSA 1IW7D 3MCJA 3OI9A 4CT8A 1O8QA 1UZ5A 5G2RA 1IHCA 5DMHA 2NQKA 1T3EA 1EAVA 2X3LA 4LHBA 1MKZA 5D6GA 4CTAA 2PBQA 3KBQA 2IS8A 2NQNA 2F7WA 4UUWA 2QQ1A 2NROA 1FC5A 5G2SA 4XCWA 5D8HB 2NQSA 3RFQA 2G4RA 2NQQA 2F7YA 3PZYA 2G2CA 4TK1A 2NQMA 1YZYA 4U91A 5ERUA 3MCHA 1DI7A 2NRPA
chains in the Genus database with same CATH topology
1WU2A 1DI6A 4PD0A 1G8RA 4TK3A 4CTAB 5ERQA 1JLJA 1Y5EA 1XI8A 4U90A 2NQRA 4TWGA 3MCIA 1O8NA 1R2KA 1G8LA 4PD1A 4UOCA 2FTSA 5ERRA 1UUYA 4TK4A 2NQUA 1I6VD 4UUXA 2NQVA 3K6AA 3TCRA 1O8OA 3IWTA 4NWOA 2NRSA 2FU3A 5ERVA 1HQMD 4NWBA 1UUXA 5ERTA 3JSYA 4CT9A 5ERSA 1IW7D 3MCJA 3OI9A 4CT8A 1O8QA 1UZ5A 5G2RA 1IHCA 2NQKA 1T3EA 1EAVA 2X3LA 4LHBA 1MKZA 5D6GA 4CTAA 2PBQA 3KBQA 2IS8A 2NQNA 2F7WA 4UUWA 2QQ1A 2NROA 1FC5A 5G2SA 4XCWA 5D8HB 2NQSA 3RFQA 2G4RA 2NQQA 2F7YA 3PZYA 2G2CA 4TK1A 2NQMA 4U91A 5ERUA 3MCHA 1DI7A 2NRPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WU2 A;  1DI6 A;  4PD0 A;  1G8R A;  4TK3 A;  4CTA B;  5ERQ A;  1JLJ A;  1Y5E A;  1XI8 A;  4U90 A;  2NQR A;  4TWG A;  3MCI A;  1O8N A;  1R2K A;  1G8L A;  4PD1 A;  4UOC A;  2FTS A;  5ERR A;  1UUY A;  4TK4 A;  2NQU A;  4UUX A;  2NQV A;  3K6A A;  3TCR A;  1O8O A;  3IWT A;  4NWO A;  2NRS A;  2FU3 A;  5ERV A;  1UUX A;  5ERT A;  4CT9 A;  5ERS A;  3MCJ A;  3OI9 A;  4CT8 A;  1O8Q A;  1UZ5 A;  5G2R A;  1IHC A;  2NQK A;  1T3E A;  1EAV A;  2X3L A;  4LHB A;  1MKZ A;  4CTA A;  2PBQ A;  3KBQ A;  2IS8 A;  2NQN A;  2F7W A;  4UUW A;  2QQ1 A;  2NRO A;  1FC5 A;  5G2S A;  4XCW A;  2NQS A;  3RFQ A;  2G4R A;  2NQQ A;  2F7Y A;  3PZY A;  2G2C A;  4TK1 A;  2NQM A;  4U91 A;  5ERU A;  3MCH A;  1DI7 A;  2NRP A; 
#chains in the Genus database with same CATH topology
 1WU2 A;  1DI6 A;  4PD0 A;  1G8R A;  4TK3 A;  4CTA B;  5ERQ A;  1JLJ A;  1Y5E A;  1XI8 A;  4U90 A;  2NQR A;  4TWG A;  3MCI A;  1O8N A;  1R2K A;  1G8L A;  4PD1 A;  4UOC A;  2FTS A;  5ERR A;  1UUY A;  4TK4 A;  2NQU A;  1I6V D;  4UUX A;  2NQV A;  3K6A A;  3TCR A;  1O8O A;  3IWT A;  4NWO A;  3DQQ A;  2NRS A;  2FU3 A;  5ERV A;  1HQM D;  4NWB A;  1UUX A;  5ERT A;  3JSY A;  4CT9 A;  5ERS A;  1IW7 D;  3MCJ A;  3OI9 A;  4CT8 A;  1O8Q A;  1UZ5 A;  5G2R A;  1IHC A;  5DMH A;  2NQK A;  1T3E A;  1EAV A;  2X3L A;  4LHB A;  1MKZ A;  5D6G A;  4CTA A;  2PBQ A;  3KBQ A;  2IS8 A;  2NQN A;  2F7W A;  4UUW A;  2QQ1 A;  2NRO A;  1FC5 A;  5G2S A;  4XCW A;  5D8H B;  2NQS A;  3RFQ A;  2G4R A;  2NQQ A;  2F7Y A;  3PZY A;  2G2C A;  4TK1 A;  2NQM A;  1YZY A;  4U91 A;  5ERU A;  3MCH A;  1DI7 A;  2NRP A; 
#chains in the Genus database with same CATH homology
 1WU2 A;  1DI6 A;  4PD0 A;  1G8R A;  4TK3 A;  4CTA B;  5ERQ A;  1JLJ A;  1Y5E A;  1XI8 A;  4U90 A;  2NQR A;  4TWG A;  3MCI A;  1O8N A;  1R2K A;  1G8L A;  4PD1 A;  4UOC A;  2FTS A;  5ERR A;  1UUY A;  4TK4 A;  2NQU A;  1I6V D;  4UUX A;  2NQV A;  3K6A A;  3TCR A;  1O8O A;  3IWT A;  4NWO A;  2NRS A;  2FU3 A;  5ERV A;  1HQM D;  4NWB A;  1UUX A;  5ERT A;  3JSY A;  4CT9 A;  5ERS A;  1IW7 D;  3MCJ A;  3OI9 A;  4CT8 A;  1O8Q A;  1UZ5 A;  5G2R A;  1IHC A;  2NQK A;  1T3E A;  1EAV A;  2X3L A;  4LHB A;  1MKZ A;  5D6G A;  4CTA A;  2PBQ A;  3KBQ A;  2IS8 A;  2NQN A;  2F7W A;  4UUW A;  2QQ1 A;  2NRO A;  1FC5 A;  5G2S A;  4XCW A;  5D8H B;  2NQS A;  3RFQ A;  2G4R A;  2NQQ A;  2F7Y A;  3PZY A;  2G2C A;  4TK1 A;  2NQM A;  4U91 A;  5ERU A;  3MCH A;  1DI7 A;  2NRP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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