2O3BA

Crystal structure complex of nuclease a (nuca) with intra-cellular inhibitor nuia
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
241
structure length
241
Chain Sequence
GSISVHLLLGNPSGATPTKLTPDNYLMVKNQYALSYNNSKGTANWVAWQLNSSWLGNAERQDNFRPDKTLPAGWVRVTPSMYSGSGYARGHIAPSADRTKTTEDNAATFLMTNMMPQTPDNNRNTWGNLEDYCRELVSQGKELYIVAGPNGSLGKPLKGKVTVPKSTWKIVVVLDSPGSGLEGITANTRVIAVNIPNDPELNNDWRAYKVSVDELESLTGYDFLSNVSPNIQTSIESKVDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The nuclease a-inhibitor complex is characterized by a novel metal ion bridge.
pubmed doi rcsb
molecule keywords Nuclease
molecule tags Hydrolase/hydrolase inhibitor
source organism Nostoc sp.
total genus 73
structure length 241
sequence length 241
ec nomenclature ec 3.1.30.-:
pdb deposition date 2006-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 2o3bA00
4ZG6A 5DLVA 5HRTA 5KXAA 3WAVA 1QL0A 4GTXA 2XH3A 4GTZA 5DLTA 5GKCA 4ZG9A 1ZM8A 2XGRA 1QAEA 4ZGAA 3S5BA 5L0BA 4QN0A 2XR9A 1G8TA 3NKRA 5DLWA 2O3BA 4E3YA 5LIAA 3NKQA 3NKNA 4GTWA 3WAWA 4ZG7A 4A1NA 5GKPA 3NKPA 3WAXA 2XRGA 4QH0A 4B56A 5IJQA 5IJSA 1SMNA 4QGOA 3ISMA 4GTYA 5INHA 5LQQA 3OWVA 3WAYA 3NKOA 5L0KA 5L0EA 3NKMA
chains in the Genus database with same CATH superfamily
4ZG6A 5DLVA 5HRTA 5KXAA 3WAVA 1QL0A 4GTXA 2XH3A 4GTZA 5DLTA 5GKCA 4ZG9A 1ZM8A 2XGRA 1QAEA 4ZGAA 3S5BA 5L0BA 4QN0A 2XR9A 1G8TA 3NKRA 5DLWA 2O3BA 4E3YA 5LIAA 3NKQA 3NKNA 4GTWA 3WAWA 4ZG7A 4A1NA 5GKPA 3NKPA 3WAXA 2XRGA 4QH0A 4B56A 5IJQA 5IJSA 1SMNA 4QGOA 3ISMA 4GTYA 5INHA 5LQQA 3OWVA 3WAYA 3NKOA 5L0KA 5L0EA 3NKMA
chains in the Genus database with same CATH topology
4ZG6A 5DLVA 5HRTA 5KXAA 3WAVA 1QL0A 4GTXA 2XH3A 4GTZA 5DLTA 5GKCA 4ZG9A 1ZM8A 2XGRA 1QAEA 4ZGAA 3S5BA 5L0BA 4QN0A 2XR9A 1G8TA 3NKRA 5DLWA 2O3BA 4E3YA 5LIAA 3NKQA 3NKNA 4GTWA 3WAWA 4ZG7A 4A1NA 5GKPA 3NKPA 3WAXA 2XRGA 4QH0A 4B56A 5IJQA 5IJSA 1SMNA 4QGOA 3ISMA 4GTYA 5INHA 5LQQA 3OWVA 3WAYA 3NKOA 5L0KA 5L0EA 3NKMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZG6 A;  5DLV A;  5HRT A;  5KXA A;  3WAV A;  1QL0 A;  4GTX A;  2XH3 A;  4GTZ A;  5DLT A;  5GKC A;  4ZG9 A;  1ZM8 A;  2XGR A;  1QAE A;  4ZGA A;  3S5B A;  5L0B A;  4QN0 A;  2XR9 A;  1G8T A;  3NKR A;  5DLW A;  2O3B A;  4E3Y A;  5LIA A;  3NKQ A;  3NKN A;  4GTW A;  3WAW A;  4ZG7 A;  4A1N A;  5GKP A;  3NKP A;  3WAX A;  2XRG A;  4QH0 A;  4B56 A;  5IJQ A;  5IJS A;  1SMN A;  4QGO A;  3ISM A;  4GTY A;  5INH A;  5LQQ A;  3OWV A;  3WAY A;  3NKO A;  5L0K A;  5L0E A;  3NKM A; 
#chains in the Genus database with same CATH topology
 4ZG6 A;  5DLV A;  5HRT A;  5KXA A;  3WAV A;  1QL0 A;  4GTX A;  2XH3 A;  4GTZ A;  5DLT A;  5GKC A;  4ZG9 A;  1ZM8 A;  2XGR A;  1QAE A;  4ZGA A;  3S5B A;  5L0B A;  4QN0 A;  2XR9 A;  1G8T A;  3NKR A;  5DLW A;  2O3B A;  4E3Y A;  5LIA A;  3NKQ A;  3NKN A;  4GTW A;  3WAW A;  4ZG7 A;  4A1N A;  5GKP A;  3NKP A;  3WAX A;  2XRG A;  4QH0 A;  4B56 A;  5IJQ A;  5IJS A;  1SMN A;  4QGO A;  3ISM A;  4GTY A;  5INH A;  5LQQ A;  3OWV A;  3WAY A;  3NKO A;  5L0K A;  5L0E A;  3NKM A; 
#chains in the Genus database with same CATH homology
 4ZG6 A;  5DLV A;  5HRT A;  5KXA A;  3WAV A;  1QL0 A;  4GTX A;  2XH3 A;  4GTZ A;  5DLT A;  5GKC A;  4ZG9 A;  1ZM8 A;  2XGR A;  1QAE A;  4ZGA A;  3S5B A;  5L0B A;  4QN0 A;  2XR9 A;  1G8T A;  3NKR A;  5DLW A;  2O3B A;  4E3Y A;  5LIA A;  3NKQ A;  3NKN A;  4GTW A;  3WAW A;  4ZG7 A;  4A1N A;  5GKP A;  3NKP A;  3WAX A;  2XRG A;  4QH0 A;  4B56 A;  5IJQ A;  5IJS A;  1SMN A;  4QGO A;  3ISM A;  4GTY A;  5INH A;  5LQQ A;  3OWV A;  3WAY A;  3NKO A;  5L0K A;  5L0E A;  3NKM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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