4ZG9A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 213
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
213
sequence length
803
structure length
750
Chain Sequence
SCKGRCFELQPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGRHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
total genus 213
structure length 750
sequence length 803
chains with identical sequence B
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg9A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg9A03
5GKPA 4N7TA 5EGHA 4KJGA 1ELXA 4CYRA 4TN0A 3SZZA 1KHJA 4B56A 1KH7A 1EW9A 1N2KA 2RH6A 5GOVA 3SZYA 3E2DA 3ED4A 3TX0A 2IUCB 3WAYA 1KH9A 4LR7A 5AJ9A 4UPIA 1KHKA 3NKMA 3S5BA 1EI6A 5GKCA 2GLQA 5C66A 2O3BA 3M8WA 5K4PA 5LQQA 2W5SA 3NKPA 2GSUA 3T01A 1QL0A 4GTYA 1N2LA 2IUCA 3OWVA 1ELYA 3T00A 3DPCA 2ZKTA 1ZEBA 1O99A 1ANJA 1B8JA 4CXKA 5LRNA 2D1GA 4UOOA 1EQJA 4KJDA 4LQYA 1Y7AA 1E1ZP 1KHLA 1SHNA 4NWXA 1SMNA 4FDIA 3UN2A 3UNYA 2W5WA 2XR9A 5EGEA 1G8TA 2GA3A 4LRDA 4QAXA 2QZUA 1KHNA 3IDDA 1ALHA 4KM4A 3NKRA 5GRRA 4UPHA 4UPLA 1ELZA 4ZG9A 1ED9A 3WAVA 2W5VA 4LR2A 5LRMA 1ZEDA 2W8SA 5DLVA 1EW8A 2XH3A 2W8DA 3B5QA 4NWJA 4LRAA 2GSOA 3WAXA 4LREA 4QGOA 3MK0A 1ANIA 3M8ZA 1ALIA 3Q3QA 1AJBA 1KH5A 3NKQA 1EW2A 3A52A 1K7HA 4GTZA 1E2SP 3BDHA 4ZGAA 1E33P 4CXUA 5KXAA 4CXSA 3WAWA 3KD8A 1HQAA 4LRFA 5HRTA 3T02A 5TJ3A 1ZEFA 3UO0A 1SHQA 1E3CP 3IGYB 4CYSA 5L0BA 4MIVA 4YR1A 3M7VA 4UPKA 1Y6VA 2W5RA 3NKOA 4KAVA 3BDFA 5DLWA 1URAA 3NKNA 3UN5A 5IJSA 1KH4A 3OT9A 5L0KA 4KAYA 3ISMA 1O98A 5IJQA 4LR8A 4ZG6A 4MHXA 2XGRA 4UORA 1AUKA 3DYCA 3UN3A 4LRCA 3WBHA 3MK2A 3TG0A 1P49A 1FSUA 5INHA 2IFYA 1ZM8A 3CMRA 4E3YA 4GTXA 3NVLA 3BDGB 1URBA 2W5TA 2XRGA 4LRBA 3TWZA 5DLTA 4QN0A 4MY4A 5LIAA 3MK1A 2VQRA 3LXQA 2W5QA 1QAEA 2W5XA 2X98A 1AJAA 3M8YA 1ED8A 4UOPA 4GTWA 4ZG7A 1HDHA 1EJJA 4QH0A 5L0EA 3BDGA 1HJKA 4FDJA 3IGZB 2ANHA 1ALKA 2GSNA 4A1NA 1ALJA 1AJCA 2G9YA 1AJDA 4LR9A
chains in the Genus database with same CATH superfamily
5GKPA 4N7TA 5EGHA 4KJGA 1ELXA 4CYRA 4TN0A 3SZZA 1KHJA 4B56A 1KH7A 1EW9A 1N2KA 2RH6A 5GOVA 3SZYA 3E2DA 3ED4A 3TX0A 2IUCB 3WAYA 1KH9A 4LR7A 5AJ9A 4UPIA 1KHKA 3NKMA 3S5BA 1EI6A 5GKCA 2GLQA 5C66A 2O3BA 3M8WA 5K4PA 5LQQA 2W5SA 3NKPA 2GSUA 3T01A 1QL0A 4GTYA 1N2LA 2IUCA 3OWVA 1ELYA 3T00A 3DPCA 2ZKTA 1ZEBA 1O99A 1ANJA 1B8JA 4CXKA 5LRNA 2D1GA 4UOOA 1EQJA 4KJDA 4LQYA 1Y7AA 1E1ZP 1KHLA 1SHNA 4NWXA 1SMNA 4FDIA 3UN2A 3UNYA 2W5WA 2XR9A 5EGEA 1G8TA 2GA3A 4LRDA 4QAXA 2QZUA 1KHNA 3IDDA 1ALHA 4KM4A 3NKRA 5GRRA 4UPHA 4UPLA 1ELZA 4ZG9A 1ED9A 3WAVA 2W5VA 4LR2A 5LRMA 1ZEDA 2W8SA 5DLVA 1EW8A 2XH3A 2W8DA 3B5QA 4NWJA 4LRAA 2GSOA 3WAXA 4LREA 4QGOA 3MK0A 1ANIA 3M8ZA 1ALIA 3Q3QA 1AJBA 1KH5A 3NKQA 1EW2A 3A52A 1K7HA 4GTZA 1E2SP 3BDHA 4ZGAA 1E33P 4CXUA 5KXAA 4CXSA 3WAWA 3KD8A 1HQAA 4LRFA 5HRTA 3T02A 5TJ3A 1ZEFA 3UO0A 1SHQA 1E3CP 3IGYB 4CYSA 5L0BA 4MIVA 4YR1A 3M7VA 4UPKA 1Y6VA 2W5RA 3NKOA 4KAVA 3BDFA 5DLWA 1URAA 3NKNA 3UN5A 5IJSA 1KH4A 3OT9A 5L0KA 4KAYA 3ISMA 1O98A 5IJQA 4LR8A 4ZG6A 4MHXA 2XGRA 4UORA 1AUKA 3DYCA 3UN3A 4LRCA 3WBHA 3MK2A 3TG0A 1P49A 1FSUA 5INHA 2IFYA 1ZM8A 3CMRA 4E3YA 4GTXA 3NVLA 3BDGB 1URBA 2W5TA 2XRGA 4LRBA 3TWZA 5DLTA 4QN0A 4MY4A 5LIAA 3MK1A 2VQRA 3LXQA 2W5QA 1QAEA 2W5XA 2X98A 1AJAA 3M8YA 1ED8A 4UOPA 4GTWA 4ZG7A 1HDHA 1EJJA 4QH0A 5L0EA 3BDGA 1HJKA 4FDJA 3IGZB 2ANHA 1ALKA 2GSNA 4A1NA 1ALJA 1AJCA 2G9YA 1AJDA 4LR9A
chains in the Genus database with same CATH topology
5GKPA 4N7TA 5EGHA 4KJGA 1ELXA 4CYRA 4TN0A 3SZZA 1KHJA 4B56A 1KH7A 1EW9A 1N2KA 2RH6A 5GOVA 3SZYA 3E2DA 3ED4A 3TX0A 2IUCB 3WAYA 1KH9A 4LR7A 5AJ9A 4UPIA 1KHKA 3NKMA 3S5BA 1EI6A 5GKCA 2GLQA 5C66A 2O3BA 3M8WA 5K4PA 5LQQA 2W5SA 3NKPA 2GSUA 3T01A 1QL0A 4GTYA 1N2LA 2IUCA 3OWVA 1ELYA 3T00A 3DPCA 2ZKTA 1ZEBA 1O99A 1ANJA 1B8JA 4CXKA 5LRNA 2D1GA 4UOOA 1EQJA 4KJDA 4LQYA 1Y7AA 1E1ZP 1KHLA 1SHNA 4NWXA 1SMNA 4FDIA 3UN2A 3UNYA 2W5WA 2XR9A 5EGEA 1G8TA 2GA3A 4LRDA 4QAXA 2QZUA 1KHNA 3IDDA 1ALHA 4KM4A 3NKRA 5GRRA 4UPHA 4UPLA 1ELZA 4ZG9A 1ED9A 3WAVA 2W5VA 4LR2A 5LRMA 1ZEDA 2W8SA 5DLVA 1EW8A 2XH3A 2W8DA 3B5QA 4NWJA 4LRAA 2GSOA 3WAXA 4LREA 4QGOA 3MK0A 1ANIA 3M8ZA 1ALIA 3Q3QA 1AJBA 1KH5A 3NKQA 1EW2A 3A52A 1K7HA 4GTZA 1E2SP 3BDHA 4ZGAA 1E33P 4CXUA 5KXAA 4CXSA 3WAWA 3KD8A 1HQAA 4LRFA 5HRTA 3T02A 5TJ3A 1ZEFA 3UO0A 1SHQA 1E3CP 3IGYB 4CYSA 5L0BA 4MIVA 4YR1A 3M7VA 4UPKA 1Y6VA 2W5RA 3NKOA 4KAVA 3BDFA 5DLWA 1URAA 3NKNA 3UN5A 5IJSA 1KH4A 3OT9A 5L0KA 4KAYA 3ISMA 1O98A 5IJQA 4LR8A 4ZG6A 4MHXA 2XGRA 4UORA 1AUKA 3DYCA 3UN3A 4LRCA 3WBHA 3MK2A 3TG0A 1P49A 1FSUA 5INHA 2IFYA 1ZM8A 3CMRA 4E3YA 4GTXA 3NVLA 3BDGB 1URBA 2W5TA 2XRGA 4LRBA 3TWZA 5DLTA 4QN0A 4MY4A 5LIAA 3MK1A 2VQRA 3LXQA 2W5QA 1QAEA 2W5XA 2X98A 1AJAA 3M8YA 1ED8A 4UOPA 4GTWA 4ZG7A 1HDHA 1EJJA 4QH0A 5L0EA 3BDGA 1HJKA 4FDJA 3IGZB 2ANHA 1ALKA 2GSNA 4A1NA 1ALJA 1AJCA 2G9YA 1AJDA 4LR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GKP A;  4N7T A;  5EGH A;  4KJG A;  1ELX A;  4CYR A;  4TN0 A;  3SZZ A;  1KHJ A;  4B56 A;  1KH7 A;  1EW9 A;  1N2K A;  2RH6 A;  5GOV A;  3SZY A;  3E2D A;  3ED4 A;  3TX0 A;  2IUC B;  3WAY A;  1KH9 A;  4LR7 A;  5AJ9 A;  4UPI A;  1KHK A;  3NKM A;  3S5B A;  1EI6 A;  5GKC A;  2GLQ A;  5C66 A;  2O3B A;  3M8W A;  5K4P A;  5LQQ A;  2W5S A;  3NKP A;  2GSU A;  3T01 A;  1QL0 A;  4GTY A;  1N2L A;  2IUC A;  3OWV A;  1ELY A;  3T00 A;  3DPC A;  2ZKT A;  1ZEB A;  1O99 A;  1ANJ A;  1B8J A;  4CXK A;  5LRN A;  2D1G A;  4UOO A;  1EQJ A;  4KJD A;  4LQY A;  1Y7A A;  1E1Z P;  1KHL A;  1SHN A;  4NWX A;  1SMN A;  4FDI A;  3UN2 A;  3UNY A;  2W5W A;  2XR9 A;  5EGE A;  1G8T A;  2GA3 A;  4LRD A;  4QAX A;  2QZU A;  1KHN A;  3IDD A;  1ALH A;  4KM4 A;  3NKR A;  5GRR A;  4UPH A;  4UPL A;  1ELZ A;  4ZG9 A;  1ED9 A;  3WAV A;  2W5V A;  4LR2 A;  5LRM A;  1ZED A;  2W8S A;  5DLV A;  1EW8 A;  2XH3 A;  2W8D A;  3B5Q A;  4NWJ A;  4LRA A;  2GSO A;  3WAX A;  4LRE A;  4QGO A;  3MK0 A;  1ANI A;  3M8Z A;  1ALI A;  3Q3Q A;  1AJB A;  1KH5 A;  3NKQ A;  1EW2 A;  3A52 A;  1K7H A;  4GTZ A;  1E2S P;  3BDH A;  4ZGA A;  1E33 P;  4CXU A;  5KXA A;  4CXS A;  3WAW A;  3KD8 A;  1HQA A;  4LRF A;  5HRT A;  3T02 A;  5TJ3 A;  1ZEF A;  3UO0 A;  1SHQ A;  1E3C P;  3IGY B;  4CYS A;  5L0B A;  4MIV A;  4YR1 A;  3M7V A;  4UPK A;  1Y6V A;  2W5R A;  3NKO A;  4KAV A;  3BDF A;  5DLW A;  1URA A;  3NKN A;  3UN5 A;  5IJS A;  1KH4 A;  3OT9 A;  5L0K A;  4KAY A;  3ISM A;  1O98 A;  5IJQ A;  4LR8 A;  4ZG6 A;  4MHX A;  2XGR A;  4UOR A;  1AUK A;  3DYC A;  3UN3 A;  4LRC A;  3WBH A;  3MK2 A;  3TG0 A;  1P49 A;  1FSU A;  5INH A;  2IFY A;  1ZM8 A;  3CMR A;  4E3Y A;  4GTX A;  3NVL A;  3BDG B;  1URB A;  2W5T A;  2XRG A;  4LRB A;  3TWZ A;  5DLT A;  4QN0 A;  4MY4 A;  5LIA A;  3MK1 A;  2VQR A;  3LXQ A;  2W5Q A;  1QAE A;  2W5X A;  2X98 A;  1AJA A;  3M8Y A;  1ED8 A;  4UOP A;  4GTW A;  4ZG7 A;  1HDH A;  1EJJ A;  4QH0 A;  5L0E A;  3BDG A;  1HJK A;  4FDJ A;  3IGZ B;  2ANH A;  1ALK A;  2GSN A;  4A1N A;  1ALJ A;  1AJC A;  2G9Y A;  1AJD A;  4LR9 A; 
#chains in the Genus database with same CATH topology
 5GKP A;  4N7T A;  5EGH A;  4KJG A;  1ELX A;  4CYR A;  4TN0 A;  3SZZ A;  1KHJ A;  4B56 A;  1KH7 A;  1EW9 A;  1N2K A;  2RH6 A;  5GOV A;  3SZY A;  3E2D A;  3ED4 A;  3TX0 A;  2IUC B;  3WAY A;  1KH9 A;  4LR7 A;  5AJ9 A;  4UPI A;  1KHK A;  3NKM A;  3S5B A;  1EI6 A;  5GKC A;  2GLQ A;  5C66 A;  2O3B A;  3M8W A;  5K4P A;  5LQQ A;  2W5S A;  3NKP A;  2GSU A;  3T01 A;  1QL0 A;  4GTY A;  1N2L A;  2IUC A;  3OWV A;  1ELY A;  3T00 A;  3DPC A;  2ZKT A;  1ZEB A;  1O99 A;  1ANJ A;  1B8J A;  4CXK A;  5LRN A;  2D1G A;  4UOO A;  1EQJ A;  4KJD A;  4LQY A;  1Y7A A;  1E1Z P;  1KHL A;  1SHN A;  4NWX A;  1SMN A;  4FDI A;  3UN2 A;  3UNY A;  2W5W A;  2XR9 A;  5EGE A;  1G8T A;  2GA3 A;  4LRD A;  4QAX A;  2QZU A;  1KHN A;  3IDD A;  1ALH A;  4KM4 A;  3NKR A;  5GRR A;  4UPH A;  4UPL A;  1ELZ A;  4ZG9 A;  1ED9 A;  3WAV A;  2W5V A;  4LR2 A;  5LRM A;  1ZED A;  2W8S A;  5DLV A;  1EW8 A;  2XH3 A;  2W8D A;  3B5Q A;  4NWJ A;  4LRA A;  2GSO A;  3WAX A;  4LRE A;  4QGO A;  3MK0 A;  1ANI A;  3M8Z A;  1ALI A;  3Q3Q A;  1AJB A;  1KH5 A;  3NKQ A;  1EW2 A;  3A52 A;  1K7H A;  4GTZ A;  1E2S P;  3BDH A;  4ZGA A;  1E33 P;  4CXU A;  5KXA A;  4CXS A;  3WAW A;  3KD8 A;  1HQA A;  4LRF A;  5HRT A;  3T02 A;  5TJ3 A;  1ZEF A;  3UO0 A;  1SHQ A;  1E3C P;  3IGY B;  4CYS A;  5L0B A;  4MIV A;  4YR1 A;  3M7V A;  4UPK A;  1Y6V A;  2W5R A;  3NKO A;  4KAV A;  3BDF A;  5DLW A;  1URA A;  3NKN A;  3UN5 A;  5IJS A;  1KH4 A;  3OT9 A;  5L0K A;  4KAY A;  3ISM A;  1O98 A;  5IJQ A;  4LR8 A;  4ZG6 A;  4MHX A;  2XGR A;  4UOR A;  1AUK A;  3DYC A;  3UN3 A;  4LRC A;  3WBH A;  3MK2 A;  3TG0 A;  1P49 A;  1FSU A;  5INH A;  2IFY A;  1ZM8 A;  3CMR A;  4E3Y A;  4GTX A;  3NVL A;  3BDG B;  1URB A;  2W5T A;  2XRG A;  4LRB A;  3TWZ A;  5DLT A;  4QN0 A;  4MY4 A;  5LIA A;  3MK1 A;  2VQR A;  3LXQ A;  2W5Q A;  1QAE A;  2W5X A;  2X98 A;  1AJA A;  3M8Y A;  1ED8 A;  4UOP A;  4GTW A;  4ZG7 A;  1HDH A;  1EJJ A;  4QH0 A;  5L0E A;  3BDG A;  1HJK A;  4FDJ A;  3IGZ B;  2ANH A;  1ALK A;  2GSN A;  4A1N A;  1ALJ A;  1AJC A;  2G9Y A;  1AJD A;  4LR9 A; 
#chains in the Genus database with same CATH homology
 5GKP A;  4N7T A;  5EGH A;  4KJG A;  1ELX A;  4CYR A;  4TN0 A;  3SZZ A;  1KHJ A;  4B56 A;  1KH7 A;  1EW9 A;  1N2K A;  2RH6 A;  5GOV A;  3SZY A;  3E2D A;  3ED4 A;  3TX0 A;  2IUC B;  3WAY A;  1KH9 A;  4LR7 A;  5AJ9 A;  4UPI A;  1KHK A;  3NKM A;  3S5B A;  1EI6 A;  5GKC A;  2GLQ A;  5C66 A;  2O3B A;  3M8W A;  5K4P A;  5LQQ A;  2W5S A;  3NKP A;  2GSU A;  3T01 A;  1QL0 A;  4GTY A;  1N2L A;  2IUC A;  3OWV A;  1ELY A;  3T00 A;  3DPC A;  2ZKT A;  1ZEB A;  1O99 A;  1ANJ A;  1B8J A;  4CXK A;  5LRN A;  2D1G A;  4UOO A;  1EQJ A;  4KJD A;  4LQY A;  1Y7A A;  1E1Z P;  1KHL A;  1SHN A;  4NWX A;  1SMN A;  4FDI A;  3UN2 A;  3UNY A;  2W5W A;  2XR9 A;  5EGE A;  1G8T A;  2GA3 A;  4LRD A;  4QAX A;  2QZU A;  1KHN A;  3IDD A;  1ALH A;  4KM4 A;  3NKR A;  5GRR A;  4UPH A;  4UPL A;  1ELZ A;  4ZG9 A;  1ED9 A;  3WAV A;  2W5V A;  4LR2 A;  5LRM A;  1ZED A;  2W8S A;  5DLV A;  1EW8 A;  2XH3 A;  2W8D A;  3B5Q A;  4NWJ A;  4LRA A;  2GSO A;  3WAX A;  4LRE A;  4QGO A;  3MK0 A;  1ANI A;  3M8Z A;  1ALI A;  3Q3Q A;  1AJB A;  1KH5 A;  3NKQ A;  1EW2 A;  3A52 A;  1K7H A;  4GTZ A;  1E2S P;  3BDH A;  4ZGA A;  1E33 P;  4CXU A;  5KXA A;  4CXS A;  3WAW A;  3KD8 A;  1HQA A;  4LRF A;  5HRT A;  3T02 A;  5TJ3 A;  1ZEF A;  3UO0 A;  1SHQ A;  1E3C P;  3IGY B;  4CYS A;  5L0B A;  4MIV A;  4YR1 A;  3M7V A;  4UPK A;  1Y6V A;  2W5R A;  3NKO A;  4KAV A;  3BDF A;  5DLW A;  1URA A;  3NKN A;  3UN5 A;  5IJS A;  1KH4 A;  3OT9 A;  5L0K A;  4KAY A;  3ISM A;  1O98 A;  5IJQ A;  4LR8 A;  4ZG6 A;  4MHX A;  2XGR A;  4UOR A;  1AUK A;  3DYC A;  3UN3 A;  4LRC A;  3WBH A;  3MK2 A;  3TG0 A;  1P49 A;  1FSU A;  5INH A;  2IFY A;  1ZM8 A;  3CMR A;  4E3Y A;  4GTX A;  3NVL A;  3BDG B;  1URB A;  2W5T A;  2XRG A;  4LRB A;  3TWZ A;  5DLT A;  4QN0 A;  4MY4 A;  5LIA A;  3MK1 A;  2VQR A;  3LXQ A;  2W5Q A;  1QAE A;  2W5X A;  2X98 A;  1AJA A;  3M8Y A;  1ED8 A;  4UOP A;  4GTW A;  4ZG7 A;  1HDH A;  1EJJ A;  4QH0 A;  5L0E A;  3BDG A;  1HJK A;  4FDJ A;  3IGZ B;  2ANH A;  1ALK A;  2GSN A;  4A1N A;  1ALJ A;  1AJC A;  2G9Y A;  1AJD A;  4LR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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