3OWVA

Structural insights into catalytic and substrate binding mechanisms of the strategic enda nuclease from streptococcus pneumoniae
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
229
structure length
218
Chain Sequence
SEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYSWTPPGWHQVKNLKGSYTHAVDRGALLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
pubmed doi rcsb
molecule tags Hydrolase
source organism Streptococcus pneumoniae
molecule keywords DNA-entry nuclease
total genus 59
structure length 218
sequence length 229
chains with identical sequence B
ec nomenclature ec 3.1.30.-:
pdb deposition date 2010-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3owvA00
4A1NA 4B56A 5L0BA 3NKNA 3NKOA 2XR9A 4QN0A 3NKQA 4GTZA 5IJSA 5L0EA 5L0KA 4GTYA 1QAEA 5GKCA 5INHA 5DLVA 5DLTA 3WAWA 2XRGA 2XH3A 4ZG7A 4QH0A 5IJQA 4ZG6A 3NKPA 5LQQA 3WAYA 4QGOA 4GTXA 4ZG9A 1SMNA 5HRTA 1QL0A 5DLWA 3WAXA 1G8TA 3ISMA 2XGRA 3NKRA 4GTWA 3S5BA 5KXAA 4E3YA 4ZGAA 2O3BA 1ZM8A 5GKPA 3NKMA 3WAVA 5LIAA 3OWVA
chains in the Genus database with same CATH superfamily
4A1NA 4B56A 5L0BA 3NKNA 3NKOA 2XR9A 4QN0A 3NKQA 4GTZA 5IJSA 5L0EA 5L0KA 4GTYA 1QAEA 5GKCA 5INHA 5DLVA 5DLTA 3WAWA 2XRGA 2XH3A 4ZG7A 4QH0A 5IJQA 4ZG6A 3NKPA 5LQQA 3WAYA 4QGOA 4GTXA 4ZG9A 1SMNA 5HRTA 1QL0A 5DLWA 3WAXA 1G8TA 3ISMA 2XGRA 3NKRA 4GTWA 3S5BA 5KXAA 4E3YA 4ZGAA 2O3BA 1ZM8A 5GKPA 3NKMA 3WAVA 5LIAA 3OWVA
chains in the Genus database with same CATH topology
4A1NA 4B56A 5L0BA 3NKNA 3NKOA 2XR9A 4QN0A 3NKQA 4GTZA 5IJSA 5L0EA 5L0KA 4GTYA 1QAEA 5GKCA 5INHA 5DLVA 5DLTA 3WAWA 2XRGA 2XH3A 4ZG7A 4QH0A 5IJQA 4ZG6A 3NKPA 5LQQA 3WAYA 4QGOA 4GTXA 4ZG9A 1SMNA 5HRTA 1QL0A 5DLWA 3WAXA 1G8TA 3ISMA 2XGRA 3NKRA 4GTWA 3S5BA 5KXAA 4E3YA 4ZGAA 2O3BA 1ZM8A 5GKPA 3NKMA 3WAVA 5LIAA 3OWVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A1N A;  4B56 A;  5L0B A;  3NKN A;  3NKO A;  2XR9 A;  4QN0 A;  3NKQ A;  4GTZ A;  5IJS A;  5L0E A;  5L0K A;  4GTY A;  1QAE A;  5GKC A;  5INH A;  5DLV A;  5DLT A;  3WAW A;  2XRG A;  2XH3 A;  4ZG7 A;  4QH0 A;  5IJQ A;  4ZG6 A;  3NKP A;  5LQQ A;  3WAY A;  4QGO A;  4GTX A;  4ZG9 A;  1SMN A;  5HRT A;  1QL0 A;  5DLW A;  3WAX A;  1G8T A;  3ISM A;  2XGR A;  3NKR A;  4GTW A;  3S5B A;  5KXA A;  4E3Y A;  4ZGA A;  2O3B A;  1ZM8 A;  5GKP A;  3NKM A;  3WAV A;  5LIA A;  3OWV A; 
#chains in the Genus database with same CATH topology
 4A1N A;  4B56 A;  5L0B A;  3NKN A;  3NKO A;  2XR9 A;  4QN0 A;  3NKQ A;  4GTZ A;  5IJS A;  5L0E A;  5L0K A;  4GTY A;  1QAE A;  5GKC A;  5INH A;  5DLV A;  5DLT A;  3WAW A;  2XRG A;  2XH3 A;  4ZG7 A;  4QH0 A;  5IJQ A;  4ZG6 A;  3NKP A;  5LQQ A;  3WAY A;  4QGO A;  4GTX A;  4ZG9 A;  1SMN A;  5HRT A;  1QL0 A;  5DLW A;  3WAX A;  1G8T A;  3ISM A;  2XGR A;  3NKR A;  4GTW A;  3S5B A;  5KXA A;  4E3Y A;  4ZGA A;  2O3B A;  1ZM8 A;  5GKP A;  3NKM A;  3WAV A;  5LIA A;  3OWV A; 
#chains in the Genus database with same CATH homology
 4A1N A;  4B56 A;  5L0B A;  3NKN A;  3NKO A;  2XR9 A;  4QN0 A;  3NKQ A;  4GTZ A;  5IJS A;  5L0E A;  5L0K A;  4GTY A;  1QAE A;  5GKC A;  5INH A;  5DLV A;  5DLT A;  3WAW A;  2XRG A;  2XH3 A;  4ZG7 A;  4QH0 A;  5IJQ A;  4ZG6 A;  3NKP A;  5LQQ A;  3WAY A;  4QGO A;  4GTX A;  4ZG9 A;  1SMN A;  5HRT A;  1QL0 A;  5DLW A;  3WAX A;  1G8T A;  3ISM A;  2XGR A;  3NKR A;  4GTW A;  3S5B A;  5KXA A;  4E3Y A;  4ZGA A;  2O3B A;  1ZM8 A;  5GKP A;  3NKM A;  3WAV A;  5LIA A;  3OWV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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