4ZG7A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 247
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
Knots found
sequence length
806
structure length
776
Chain Sequence
ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIAALTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
total genus 247
structure length 776
sequence length 806
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg7A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg7A03
4LRDA 4LR7A 3NVLA 4TN0A 4CYSA 5LRNA 1ELZA 5C66A 4GTYA 1O98A 1KHJA 1HJKA 5DLWA 3WAYA 4A1NA 2W5VA 5IJSA 1P49A 3LXQA 1ED8A 5GOVA 1AJDA 2W5RA 3MK2A 1KH5A 3UN3A 5K4PA 5KXAA 2G9YA 2X98A 3M8YA 1N2LA 4B56A 4LRFA 4UPKA 4N7TA 1Y6VA 2GSOA 3T02A 1ZEBA 4ZGAA 5L0BA 1KH7A 2RH6A 5HRTA 1O99A 3UN2A 2IUCB 3SZZA 1EJJA 4CYRA 2QZUA 2XRGA 3TWZA 2W8DA 3IGZB 2W5WA 2XR9A 4QN0A 1E1ZP 2ANHA 5LRMA 4E3YA 1ALIA 3WAWA 3NKNA 4GTWA 5L0KA 2W8SA 1ZM8A 4LR2A 4LRAA 2XGRA 3TG0A 2O3BA 4LR8A 2VQRA 4QGOA 1E3CP 4KAVA 2W5QA 3WAXA 4UORA 4UPHA 1URBA 1EW8A 1ANIA 4ZG9A 5AJ9A 1AJCA 1ED9A 4UOPA 3M8WA 5EGHA 1AJBA 2GA3A 4ZG6A 1ANJA 1EQJA 3BDHA 3M8ZA 2W5TA 3M7VA 4GTXA 1ALJA 4FDJA 2IUCA 4UOOA 5GKCA 3SZYA 1AJAA 1E33P 2GSNA 4LRCA 4LRBA 1E2SP 2IFYA 2W5XA 4KJDA 5INHA 5GKPA 1EI6A 4YR1A 1EW2A 1SMNA 3OT9A 4LR9A 1ALKA 4CXSA 3B5QA 4MIVA 4ZG7A 1N2KA 1HQAA 3NKMA 3E2DA 1KHLA 1ZEFA 3UN5A 1QL0A 4CXUA 3MK0A 1K7HA 4FDIA 4UPIA 4KJGA 3UO0A 1ELYA 4KM4A 3KD8A 3BDGB 4UPLA 3TX0A 3NKQA 2D1GA 3NKPA 1ELXA 3IDDA 5TJ3A 4LREA 1KH9A 1HDHA 5LQQA 3NKRA 3WAVA 4QH0A 3S5BA 1G8TA 2ZKTA 3IGYB 3MK1A 3DYCA 2GLQA 3T00A 5DLTA 3Q3QA 2XH3A 1URAA 3UNYA 3ISMA 1KHKA 5DLVA 5IJQA 4CXKA 4NWXA 3WBHA 1AUKA 5GRRA 4GTZA 4MHXA 3CMRA 1EW9A 1B8JA 3DPCA 4MY4A 3A52A 5LIAA 3T01A 1ZEDA 1QAEA 4QAXA 3BDGA 1FSUA 1SHNA 4KAYA 3BDFA 2W5SA 4LQYA 3OWVA 1ALHA 1KH4A 5L0EA 4NWJA 2GSUA 5EGEA 1Y7AA 1SHQA 3ED4A 1KHNA 3NKOA
chains in the Genus database with same CATH superfamily
4LRDA 4LR7A 3NVLA 4TN0A 4CYSA 5LRNA 1ELZA 5C66A 4GTYA 1O98A 1KHJA 1HJKA 5DLWA 3WAYA 4A1NA 2W5VA 5IJSA 1P49A 3LXQA 1ED8A 5GOVA 1AJDA 2W5RA 3MK2A 1KH5A 3UN3A 5K4PA 5KXAA 2G9YA 2X98A 3M8YA 1N2LA 4B56A 4LRFA 4UPKA 4N7TA 1Y6VA 2GSOA 3T02A 1ZEBA 4ZGAA 5L0BA 1KH7A 2RH6A 5HRTA 1O99A 3UN2A 2IUCB 3SZZA 1EJJA 4CYRA 2QZUA 2XRGA 3TWZA 2W8DA 3IGZB 2W5WA 2XR9A 4QN0A 1E1ZP 2ANHA 5LRMA 4E3YA 1ALIA 3WAWA 3NKNA 4GTWA 5L0KA 2W8SA 1ZM8A 4LR2A 4LRAA 2XGRA 3TG0A 2O3BA 4LR8A 2VQRA 4QGOA 1E3CP 4KAVA 2W5QA 3WAXA 4UORA 4UPHA 1URBA 1EW8A 1ANIA 4ZG9A 5AJ9A 1AJCA 1ED9A 4UOPA 3M8WA 5EGHA 1AJBA 2GA3A 4ZG6A 1ANJA 1EQJA 3BDHA 3M8ZA 2W5TA 3M7VA 4GTXA 1ALJA 4FDJA 2IUCA 4UOOA 5GKCA 3SZYA 1AJAA 1E33P 2GSNA 4LRCA 4LRBA 1E2SP 2IFYA 2W5XA 4KJDA 5INHA 5GKPA 1EI6A 4YR1A 1EW2A 1SMNA 3OT9A 4LR9A 1ALKA 4CXSA 3B5QA 4MIVA 4ZG7A 1N2KA 1HQAA 3NKMA 3E2DA 1KHLA 1ZEFA 3UN5A 1QL0A 4CXUA 3MK0A 1K7HA 4FDIA 4UPIA 4KJGA 3UO0A 1ELYA 4KM4A 3KD8A 3BDGB 4UPLA 3TX0A 3NKQA 2D1GA 3NKPA 1ELXA 3IDDA 5TJ3A 4LREA 1KH9A 1HDHA 5LQQA 3NKRA 3WAVA 4QH0A 3S5BA 1G8TA 2ZKTA 3IGYB 3MK1A 3DYCA 2GLQA 3T00A 5DLTA 3Q3QA 2XH3A 1URAA 3UNYA 3ISMA 1KHKA 5DLVA 5IJQA 4CXKA 4NWXA 3WBHA 1AUKA 5GRRA 4GTZA 4MHXA 3CMRA 1EW9A 1B8JA 3DPCA 4MY4A 3A52A 5LIAA 3T01A 1ZEDA 1QAEA 4QAXA 3BDGA 1FSUA 1SHNA 4KAYA 3BDFA 2W5SA 4LQYA 3OWVA 1ALHA 1KH4A 5L0EA 4NWJA 2GSUA 5EGEA 1Y7AA 1SHQA 3ED4A 1KHNA 3NKOA
chains in the Genus database with same CATH topology
4LRDA 4LR7A 3NVLA 4TN0A 4CYSA 5LRNA 1ELZA 5C66A 4GTYA 1O98A 1KHJA 1HJKA 5DLWA 3WAYA 4A1NA 2W5VA 5IJSA 1P49A 3LXQA 1ED8A 5GOVA 1AJDA 2W5RA 3MK2A 1KH5A 3UN3A 5K4PA 5KXAA 2G9YA 2X98A 3M8YA 1N2LA 4B56A 4LRFA 4UPKA 4N7TA 1Y6VA 2GSOA 3T02A 1ZEBA 4ZGAA 5L0BA 1KH7A 2RH6A 5HRTA 1O99A 3UN2A 2IUCB 3SZZA 1EJJA 4CYRA 2QZUA 2XRGA 3TWZA 2W8DA 3IGZB 2W5WA 2XR9A 4QN0A 1E1ZP 2ANHA 5LRMA 4E3YA 1ALIA 3WAWA 3NKNA 4GTWA 5L0KA 2W8SA 1ZM8A 4LR2A 4LRAA 2XGRA 3TG0A 2O3BA 4LR8A 2VQRA 4QGOA 1E3CP 4KAVA 2W5QA 3WAXA 4UORA 4UPHA 1URBA 1EW8A 1ANIA 4ZG9A 5AJ9A 1AJCA 1ED9A 4UOPA 3M8WA 5EGHA 1AJBA 2GA3A 4ZG6A 1ANJA 1EQJA 3BDHA 3M8ZA 2W5TA 3M7VA 4GTXA 1ALJA 4FDJA 2IUCA 4UOOA 5GKCA 3SZYA 1AJAA 1E33P 2GSNA 4LRCA 4LRBA 1E2SP 2IFYA 2W5XA 4KJDA 5INHA 5GKPA 1EI6A 4YR1A 1EW2A 1SMNA 3OT9A 4LR9A 1ALKA 4CXSA 3B5QA 4MIVA 4ZG7A 1N2KA 1HQAA 3NKMA 3E2DA 1KHLA 1ZEFA 3UN5A 1QL0A 4CXUA 3MK0A 1K7HA 4FDIA 4UPIA 4KJGA 3UO0A 1ELYA 4KM4A 3KD8A 3BDGB 4UPLA 3TX0A 3NKQA 2D1GA 3NKPA 1ELXA 3IDDA 5TJ3A 4LREA 1KH9A 1HDHA 5LQQA 3NKRA 3WAVA 4QH0A 3S5BA 1G8TA 2ZKTA 3IGYB 3MK1A 3DYCA 2GLQA 3T00A 5DLTA 3Q3QA 2XH3A 1URAA 3UNYA 3ISMA 1KHKA 5DLVA 5IJQA 4CXKA 4NWXA 3WBHA 1AUKA 5GRRA 4GTZA 4MHXA 3CMRA 1EW9A 1B8JA 3DPCA 4MY4A 3A52A 5LIAA 3T01A 1ZEDA 1QAEA 4QAXA 3BDGA 1FSUA 1SHNA 4KAYA 3BDFA 2W5SA 4LQYA 3OWVA 1ALHA 1KH4A 5L0EA 4NWJA 2GSUA 5EGEA 1Y7AA 1SHQA 3ED4A 1KHNA 3NKOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LRD A;  4LR7 A;  3NVL A;  4TN0 A;  4CYS A;  5LRN A;  1ELZ A;  5C66 A;  4GTY A;  1O98 A;  1KHJ A;  1HJK A;  5DLW A;  3WAY A;  4A1N A;  2W5V A;  5IJS A;  1P49 A;  3LXQ A;  1ED8 A;  5GOV A;  1AJD A;  2W5R A;  3MK2 A;  1KH5 A;  3UN3 A;  5K4P A;  5KXA A;  2G9Y A;  2X98 A;  3M8Y A;  1N2L A;  4B56 A;  4LRF A;  4UPK A;  4N7T A;  1Y6V A;  2GSO A;  3T02 A;  1ZEB A;  4ZGA A;  5L0B A;  1KH7 A;  2RH6 A;  5HRT A;  1O99 A;  3UN2 A;  2IUC B;  3SZZ A;  1EJJ A;  4CYR A;  2QZU A;  2XRG A;  3TWZ A;  2W8D A;  3IGZ B;  2W5W A;  2XR9 A;  4QN0 A;  1E1Z P;  2ANH A;  5LRM A;  4E3Y A;  1ALI A;  3WAW A;  3NKN A;  4GTW A;  5L0K A;  2W8S A;  1ZM8 A;  4LR2 A;  4LRA A;  2XGR A;  3TG0 A;  2O3B A;  4LR8 A;  2VQR A;  4QGO A;  1E3C P;  4KAV A;  2W5Q A;  3WAX A;  4UOR A;  4UPH A;  1URB A;  1EW8 A;  1ANI A;  4ZG9 A;  5AJ9 A;  1AJC A;  1ED9 A;  4UOP A;  3M8W A;  5EGH A;  1AJB A;  2GA3 A;  4ZG6 A;  1ANJ A;  1EQJ A;  3BDH A;  3M8Z A;  2W5T A;  3M7V A;  4GTX A;  1ALJ A;  4FDJ A;  2IUC A;  4UOO A;  5GKC A;  3SZY A;  1AJA A;  1E33 P;  2GSN A;  4LRC A;  4LRB A;  1E2S P;  2IFY A;  2W5X A;  4KJD A;  5INH A;  5GKP A;  1EI6 A;  4YR1 A;  1EW2 A;  1SMN A;  3OT9 A;  4LR9 A;  1ALK A;  4CXS A;  3B5Q A;  4MIV A;  4ZG7 A;  1N2K A;  1HQA A;  3NKM A;  3E2D A;  1KHL A;  1ZEF A;  3UN5 A;  1QL0 A;  4CXU A;  3MK0 A;  1K7H A;  4FDI A;  4UPI A;  4KJG A;  3UO0 A;  1ELY A;  4KM4 A;  3KD8 A;  3BDG B;  4UPL A;  3TX0 A;  3NKQ A;  2D1G A;  3NKP A;  1ELX A;  3IDD A;  5TJ3 A;  4LRE A;  1KH9 A;  1HDH A;  5LQQ A;  3NKR A;  3WAV A;  4QH0 A;  3S5B A;  1G8T A;  2ZKT A;  3IGY B;  3MK1 A;  3DYC A;  2GLQ A;  3T00 A;  5DLT A;  3Q3Q A;  2XH3 A;  1URA A;  3UNY A;  3ISM A;  1KHK A;  5DLV A;  5IJQ A;  4CXK A;  4NWX A;  3WBH A;  1AUK A;  5GRR A;  4GTZ A;  4MHX A;  3CMR A;  1EW9 A;  1B8J A;  3DPC A;  4MY4 A;  3A52 A;  5LIA A;  3T01 A;  1ZED A;  1QAE A;  4QAX A;  3BDG A;  1FSU A;  1SHN A;  4KAY A;  3BDF A;  2W5S A;  4LQY A;  3OWV A;  1ALH A;  1KH4 A;  5L0E A;  4NWJ A;  2GSU A;  5EGE A;  1Y7A A;  1SHQ A;  3ED4 A;  1KHN A;  3NKO A; 
#chains in the Genus database with same CATH topology
 4LRD A;  4LR7 A;  3NVL A;  4TN0 A;  4CYS A;  5LRN A;  1ELZ A;  5C66 A;  4GTY A;  1O98 A;  1KHJ A;  1HJK A;  5DLW A;  3WAY A;  4A1N A;  2W5V A;  5IJS A;  1P49 A;  3LXQ A;  1ED8 A;  5GOV A;  1AJD A;  2W5R A;  3MK2 A;  1KH5 A;  3UN3 A;  5K4P A;  5KXA A;  2G9Y A;  2X98 A;  3M8Y A;  1N2L A;  4B56 A;  4LRF A;  4UPK A;  4N7T A;  1Y6V A;  2GSO A;  3T02 A;  1ZEB A;  4ZGA A;  5L0B A;  1KH7 A;  2RH6 A;  5HRT A;  1O99 A;  3UN2 A;  2IUC B;  3SZZ A;  1EJJ A;  4CYR A;  2QZU A;  2XRG A;  3TWZ A;  2W8D A;  3IGZ B;  2W5W A;  2XR9 A;  4QN0 A;  1E1Z P;  2ANH A;  5LRM A;  4E3Y A;  1ALI A;  3WAW A;  3NKN A;  4GTW A;  5L0K A;  2W8S A;  1ZM8 A;  4LR2 A;  4LRA A;  2XGR A;  3TG0 A;  2O3B A;  4LR8 A;  2VQR A;  4QGO A;  1E3C P;  4KAV A;  2W5Q A;  3WAX A;  4UOR A;  4UPH A;  1URB A;  1EW8 A;  1ANI A;  4ZG9 A;  5AJ9 A;  1AJC A;  1ED9 A;  4UOP A;  3M8W A;  5EGH A;  1AJB A;  2GA3 A;  4ZG6 A;  1ANJ A;  1EQJ A;  3BDH A;  3M8Z A;  2W5T A;  3M7V A;  4GTX A;  1ALJ A;  4FDJ A;  2IUC A;  4UOO A;  5GKC A;  3SZY A;  1AJA A;  1E33 P;  2GSN A;  4LRC A;  4LRB A;  1E2S P;  2IFY A;  2W5X A;  4KJD A;  5INH A;  5GKP A;  1EI6 A;  4YR1 A;  1EW2 A;  1SMN A;  3OT9 A;  4LR9 A;  1ALK A;  4CXS A;  3B5Q A;  4MIV A;  4ZG7 A;  1N2K A;  1HQA A;  3NKM A;  3E2D A;  1KHL A;  1ZEF A;  3UN5 A;  1QL0 A;  4CXU A;  3MK0 A;  1K7H A;  4FDI A;  4UPI A;  4KJG A;  3UO0 A;  1ELY A;  4KM4 A;  3KD8 A;  3BDG B;  4UPL A;  3TX0 A;  3NKQ A;  2D1G A;  3NKP A;  1ELX A;  3IDD A;  5TJ3 A;  4LRE A;  1KH9 A;  1HDH A;  5LQQ A;  3NKR A;  3WAV A;  4QH0 A;  3S5B A;  1G8T A;  2ZKT A;  3IGY B;  3MK1 A;  3DYC A;  2GLQ A;  3T00 A;  5DLT A;  3Q3Q A;  2XH3 A;  1URA A;  3UNY A;  3ISM A;  1KHK A;  5DLV A;  5IJQ A;  4CXK A;  4NWX A;  3WBH A;  1AUK A;  5GRR A;  4GTZ A;  4MHX A;  3CMR A;  1EW9 A;  1B8J A;  3DPC A;  4MY4 A;  3A52 A;  5LIA A;  3T01 A;  1ZED A;  1QAE A;  4QAX A;  3BDG A;  1FSU A;  1SHN A;  4KAY A;  3BDF A;  2W5S A;  4LQY A;  3OWV A;  1ALH A;  1KH4 A;  5L0E A;  4NWJ A;  2GSU A;  5EGE A;  1Y7A A;  1SHQ A;  3ED4 A;  1KHN A;  3NKO A; 
#chains in the Genus database with same CATH homology
 4LRD A;  4LR7 A;  3NVL A;  4TN0 A;  4CYS A;  5LRN A;  1ELZ A;  5C66 A;  4GTY A;  1O98 A;  1KHJ A;  1HJK A;  5DLW A;  3WAY A;  4A1N A;  2W5V A;  5IJS A;  1P49 A;  3LXQ A;  1ED8 A;  5GOV A;  1AJD A;  2W5R A;  3MK2 A;  1KH5 A;  3UN3 A;  5K4P A;  5KXA A;  2G9Y A;  2X98 A;  3M8Y A;  1N2L A;  4B56 A;  4LRF A;  4UPK A;  4N7T A;  1Y6V A;  2GSO A;  3T02 A;  1ZEB A;  4ZGA A;  5L0B A;  1KH7 A;  2RH6 A;  5HRT A;  1O99 A;  3UN2 A;  2IUC B;  3SZZ A;  1EJJ A;  4CYR A;  2QZU A;  2XRG A;  3TWZ A;  2W8D A;  3IGZ B;  2W5W A;  2XR9 A;  4QN0 A;  1E1Z P;  2ANH A;  5LRM A;  4E3Y A;  1ALI A;  3WAW A;  3NKN A;  4GTW A;  5L0K A;  2W8S A;  1ZM8 A;  4LR2 A;  4LRA A;  2XGR A;  3TG0 A;  2O3B A;  4LR8 A;  2VQR A;  4QGO A;  1E3C P;  4KAV A;  2W5Q A;  3WAX A;  4UOR A;  4UPH A;  1URB A;  1EW8 A;  1ANI A;  4ZG9 A;  5AJ9 A;  1AJC A;  1ED9 A;  4UOP A;  3M8W A;  5EGH A;  1AJB A;  2GA3 A;  4ZG6 A;  1ANJ A;  1EQJ A;  3BDH A;  3M8Z A;  2W5T A;  3M7V A;  4GTX A;  1ALJ A;  4FDJ A;  2IUC A;  4UOO A;  5GKC A;  3SZY A;  1AJA A;  1E33 P;  2GSN A;  4LRC A;  4LRB A;  1E2S P;  2IFY A;  2W5X A;  4KJD A;  5INH A;  5GKP A;  1EI6 A;  4YR1 A;  1EW2 A;  1SMN A;  3OT9 A;  4LR9 A;  1ALK A;  4CXS A;  3B5Q A;  4MIV A;  4ZG7 A;  1N2K A;  1HQA A;  3NKM A;  3E2D A;  1KHL A;  1ZEF A;  3UN5 A;  1QL0 A;  4CXU A;  3MK0 A;  1K7H A;  4FDI A;  4UPI A;  4KJG A;  3UO0 A;  1ELY A;  4KM4 A;  3KD8 A;  3BDG B;  4UPL A;  3TX0 A;  3NKQ A;  2D1G A;  3NKP A;  1ELX A;  3IDD A;  5TJ3 A;  4LRE A;  1KH9 A;  1HDH A;  5LQQ A;  3NKR A;  3WAV A;  4QH0 A;  3S5B A;  1G8T A;  2ZKT A;  3IGY B;  3MK1 A;  3DYC A;  2GLQ A;  3T00 A;  5DLT A;  3Q3Q A;  2XH3 A;  1URA A;  3UNY A;  3ISM A;  1KHK A;  5DLV A;  5IJQ A;  4CXK A;  4NWX A;  3WBH A;  1AUK A;  5GRR A;  4GTZ A;  4MHX A;  3CMR A;  1EW9 A;  1B8J A;  3DPC A;  4MY4 A;  3A52 A;  5LIA A;  3T01 A;  1ZED A;  1QAE A;  4QAX A;  3BDG A;  1FSU A;  1SHN A;  4KAY A;  3BDF A;  2W5S A;  4LQY A;  3OWV A;  1ALH A;  1KH4 A;  5L0E A;  4NWJ A;  2GSU A;  5EGE A;  1Y7A A;  1SHQ A;  3ED4 A;  1KHN A;  3NKO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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