4ZG7A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 247
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
Knots found
sequence length
806
structure length
776
Chain Sequence
ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIAALTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 247
structure length 776
sequence length 806
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg7A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg7A03
1EQJA 3BDHA 3MK0A 3M8WA 1EW2A 1AJCA 5TJ3A 4MY4A 4CXUA 5DLWA 5LRNA 2W5SA 1AJDA 1ELZA 3TWZA 3NKOA 1Y6VA 3UN2A 2XGRA 3UO0A 1ANIA 2VQRA 2W8SA 2W5TA 4MHXA 1EW9A 4A1NA 4GTYA 2IUCA 2QZUA 5IJSA 1B8JA 3BDGB 5LIAA 3NKRA 3BDGA 4LR2A 4LRCA 2GA3A 1KH4A 2W5XA 4LR7A 3B5QA 2D1GA 3UN5A 2IFYA 5HRTA 3OWVA 1N2KA 4GTZA 4CYRA 4GTXA 3SZZA 1E33P 4B56A 3Q3QA 4LQYA 4FDJA 1KHKA 4CYSA 3ISMA 4LR9A 4UORA 4CXKA 3TX0A 5DLVA 4UPKA 4GTWA 4QGOA 4NWXA 5EGEA 2W5QA 2W5VA 2GLQA 5L0EA 1E1ZP 4KAVA 2XRGA 5K4PA 3SZYA 3ED4A 2ANHA 5EGHA 1K7HA 3T02A 3TG0A 5INHA 4E3YA 1ELYA 3IGYB 4QH0A 3NKPA 1QAEA 4ZG9A 1EJJA 4QN0A 3OT9A 1ZM8A 4LREA 5LRMA 3WAVA 3A52A 3E2DA 3DPCA 4ZGAA 4UPLA 4MIVA 3KD8A 4FDIA 1E3CP 5DLTA 5GKCA 3S5BA 1KH9A 1HJKA 3WBHA 4KJDA 5GOVA 3WAWA 4LR8A 2W5WA 4TN0A 3CMRA 2W5RA 1KH5A 4KM4A 1ANJA 4YR1A 3NKQA 2XH3A 1ZEDA 4UPHA 3T00A 1O99A 1SHQA 3WAXA 2XR9A 2GSNA 1QL0A 3IGZB 4UOPA 4CXSA 1EW8A 1ED8A 3MK1A 1EI6A 5AJ9A 3UN3A 3NVLA 1ZEBA 4ZG7A 4LRFA 2RH6A 4N7TA 1KHJA 4LRAA 1O98A 3NKNA 3UNYA 1ELXA 2ZKTA 5GRRA 1URBA 1ZEFA 3BDFA 3LXQA 3MK2A 2X98A 5KXAA 4KJGA 1HDHA 5IJQA 1KHLA 4UPIA 1ALKA 3DYCA 3WAYA 5L0KA 4NWJA 3NKMA 1N2LA 4LRBA 1SMNA 4ZG6A 3M8ZA 5L0BA 3M7VA 2O3BA 5LQQA 1SHNA 1AJBA 1HQAA 2IUCB 4QAXA 1KH7A 2GSOA 3M8YA 1ALJA 5C66A 1ALIA 2W8DA 1KHNA 1G8TA 2G9YA 4KAYA 3T01A 1E2SP 2GSUA 4LRDA 1FSUA 3IDDA 1P49A 1URAA 1AJAA 5GKPA 1AUKA 4UOOA 1Y7AA 1ED9A 1ALHA
chains in the Genus database with same CATH superfamily
1EQJA 3BDHA 3MK0A 3M8WA 1EW2A 1AJCA 5TJ3A 4MY4A 4CXUA 5DLWA 5LRNA 2W5SA 1AJDA 1ELZA 3TWZA 3NKOA 1Y6VA 3UN2A 2XGRA 3UO0A 1ANIA 2VQRA 2W8SA 2W5TA 4MHXA 1EW9A 4A1NA 4GTYA 2IUCA 2QZUA 5IJSA 1B8JA 3BDGB 5LIAA 3NKRA 3BDGA 4LR2A 4LRCA 2GA3A 1KH4A 2W5XA 4LR7A 3B5QA 2D1GA 3UN5A 2IFYA 5HRTA 3OWVA 1N2KA 4GTZA 4CYRA 4GTXA 3SZZA 1E33P 4B56A 3Q3QA 4LQYA 4FDJA 1KHKA 4CYSA 3ISMA 4LR9A 4UORA 4CXKA 3TX0A 5DLVA 4UPKA 4GTWA 4QGOA 4NWXA 5EGEA 2W5QA 2W5VA 2GLQA 5L0EA 1E1ZP 4KAVA 2XRGA 5K4PA 3SZYA 3ED4A 2ANHA 5EGHA 1K7HA 3T02A 3TG0A 5INHA 4E3YA 1ELYA 3IGYB 4QH0A 3NKPA 1QAEA 4ZG9A 1EJJA 4QN0A 3OT9A 1ZM8A 4LREA 5LRMA 3WAVA 3A52A 3E2DA 3DPCA 4ZGAA 4UPLA 4MIVA 3KD8A 4FDIA 1E3CP 5DLTA 5GKCA 3S5BA 1KH9A 1HJKA 3WBHA 4KJDA 5GOVA 3WAWA 4LR8A 2W5WA 4TN0A 3CMRA 2W5RA 1KH5A 4KM4A 1ANJA 4YR1A 3NKQA 2XH3A 1ZEDA 4UPHA 3T00A 1O99A 1SHQA 3WAXA 2XR9A 2GSNA 1QL0A 3IGZB 4UOPA 4CXSA 1EW8A 1ED8A 3MK1A 1EI6A 5AJ9A 3UN3A 3NVLA 1ZEBA 4ZG7A 4LRFA 2RH6A 4N7TA 1KHJA 4LRAA 1O98A 3NKNA 3UNYA 1ELXA 2ZKTA 5GRRA 1URBA 1ZEFA 3BDFA 3LXQA 3MK2A 2X98A 5KXAA 4KJGA 1HDHA 5IJQA 1KHLA 4UPIA 1ALKA 3DYCA 3WAYA 5L0KA 4NWJA 3NKMA 1N2LA 4LRBA 1SMNA 4ZG6A 3M8ZA 5L0BA 3M7VA 2O3BA 5LQQA 1SHNA 1AJBA 1HQAA 2IUCB 4QAXA 1KH7A 2GSOA 3M8YA 1ALJA 5C66A 1ALIA 2W8DA 1KHNA 1G8TA 2G9YA 4KAYA 3T01A 1E2SP 2GSUA 4LRDA 1FSUA 3IDDA 1P49A 1URAA 1AJAA 5GKPA 1AUKA 4UOOA 1Y7AA 1ED9A 1ALHA
chains in the Genus database with same CATH topology
1EQJA 3BDHA 3MK0A 3M8WA 1EW2A 1AJCA 5TJ3A 4MY4A 4CXUA 5DLWA 5LRNA 2W5SA 1AJDA 1ELZA 3TWZA 3NKOA 1Y6VA 3UN2A 2XGRA 3UO0A 1ANIA 2VQRA 2W8SA 2W5TA 4MHXA 1EW9A 4A1NA 4GTYA 2IUCA 2QZUA 5IJSA 1B8JA 3BDGB 5LIAA 3NKRA 3BDGA 4LR2A 4LRCA 2GA3A 1KH4A 2W5XA 4LR7A 3B5QA 2D1GA 3UN5A 2IFYA 5HRTA 3OWVA 1N2KA 4GTZA 4CYRA 4GTXA 3SZZA 1E33P 4B56A 3Q3QA 4LQYA 4FDJA 1KHKA 4CYSA 3ISMA 4LR9A 4UORA 4CXKA 3TX0A 5DLVA 4UPKA 4GTWA 4QGOA 4NWXA 5EGEA 2W5QA 2W5VA 2GLQA 5L0EA 1E1ZP 4KAVA 2XRGA 5K4PA 3SZYA 3ED4A 2ANHA 5EGHA 1K7HA 3T02A 3TG0A 5INHA 4E3YA 1ELYA 3IGYB 4QH0A 3NKPA 1QAEA 4ZG9A 1EJJA 4QN0A 3OT9A 1ZM8A 4LREA 5LRMA 3WAVA 3A52A 3E2DA 3DPCA 4ZGAA 4UPLA 4MIVA 3KD8A 4FDIA 1E3CP 5DLTA 5GKCA 3S5BA 1KH9A 1HJKA 3WBHA 4KJDA 5GOVA 3WAWA 4LR8A 2W5WA 4TN0A 3CMRA 2W5RA 1KH5A 4KM4A 1ANJA 4YR1A 3NKQA 2XH3A 1ZEDA 4UPHA 3T00A 1O99A 1SHQA 3WAXA 2XR9A 2GSNA 1QL0A 3IGZB 4UOPA 4CXSA 1EW8A 1ED8A 3MK1A 1EI6A 5AJ9A 3UN3A 3NVLA 1ZEBA 4ZG7A 4LRFA 2RH6A 4N7TA 1KHJA 4LRAA 1O98A 3NKNA 3UNYA 1ELXA 2ZKTA 5GRRA 1URBA 1ZEFA 3BDFA 3LXQA 3MK2A 2X98A 5KXAA 4KJGA 1HDHA 5IJQA 1KHLA 4UPIA 1ALKA 3DYCA 3WAYA 5L0KA 4NWJA 3NKMA 1N2LA 4LRBA 1SMNA 4ZG6A 3M8ZA 5L0BA 3M7VA 2O3BA 5LQQA 1SHNA 1AJBA 1HQAA 2IUCB 4QAXA 1KH7A 2GSOA 3M8YA 1ALJA 5C66A 1ALIA 2W8DA 1KHNA 1G8TA 2G9YA 4KAYA 3T01A 1E2SP 2GSUA 4LRDA 1FSUA 3IDDA 1P49A 1URAA 1AJAA 5GKPA 1AUKA 4UOOA 1Y7AA 1ED9A 1ALHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EQJ A;  3BDH A;  3MK0 A;  3M8W A;  1EW2 A;  1AJC A;  5TJ3 A;  4MY4 A;  4CXU A;  5DLW A;  5LRN A;  2W5S A;  1AJD A;  1ELZ A;  3TWZ A;  3NKO A;  1Y6V A;  3UN2 A;  2XGR A;  3UO0 A;  1ANI A;  2VQR A;  2W8S A;  2W5T A;  4MHX A;  1EW9 A;  4A1N A;  4GTY A;  2IUC A;  2QZU A;  5IJS A;  1B8J A;  3BDG B;  5LIA A;  3NKR A;  3BDG A;  4LR2 A;  4LRC A;  2GA3 A;  1KH4 A;  2W5X A;  4LR7 A;  3B5Q A;  2D1G A;  3UN5 A;  2IFY A;  5HRT A;  3OWV A;  1N2K A;  4GTZ A;  4CYR A;  4GTX A;  3SZZ A;  1E33 P;  4B56 A;  3Q3Q A;  4LQY A;  4FDJ A;  1KHK A;  4CYS A;  3ISM A;  4LR9 A;  4UOR A;  4CXK A;  3TX0 A;  5DLV A;  4UPK A;  4GTW A;  4QGO A;  4NWX A;  5EGE A;  2W5Q A;  2W5V A;  2GLQ A;  5L0E A;  1E1Z P;  4KAV A;  2XRG A;  5K4P A;  3SZY A;  3ED4 A;  2ANH A;  5EGH A;  1K7H A;  3T02 A;  3TG0 A;  5INH A;  4E3Y A;  1ELY A;  3IGY B;  4QH0 A;  3NKP A;  1QAE A;  4ZG9 A;  1EJJ A;  4QN0 A;  3OT9 A;  1ZM8 A;  4LRE A;  5LRM A;  3WAV A;  3A52 A;  3E2D A;  3DPC A;  4ZGA A;  4UPL A;  4MIV A;  3KD8 A;  4FDI A;  1E3C P;  5DLT A;  5GKC A;  3S5B A;  1KH9 A;  1HJK A;  3WBH A;  4KJD A;  5GOV A;  3WAW A;  4LR8 A;  2W5W A;  4TN0 A;  3CMR A;  2W5R A;  1KH5 A;  4KM4 A;  1ANJ A;  4YR1 A;  3NKQ A;  2XH3 A;  1ZED A;  4UPH A;  3T00 A;  1O99 A;  1SHQ A;  3WAX A;  2XR9 A;  2GSN A;  1QL0 A;  3IGZ B;  4UOP A;  4CXS A;  1EW8 A;  1ED8 A;  3MK1 A;  1EI6 A;  5AJ9 A;  3UN3 A;  3NVL A;  1ZEB A;  4ZG7 A;  4LRF A;  2RH6 A;  4N7T A;  1KHJ A;  4LRA A;  1O98 A;  3NKN A;  3UNY A;  1ELX A;  2ZKT A;  5GRR A;  1URB A;  1ZEF A;  3BDF A;  3LXQ A;  3MK2 A;  2X98 A;  5KXA A;  4KJG A;  1HDH A;  5IJQ A;  1KHL A;  4UPI A;  1ALK A;  3DYC A;  3WAY A;  5L0K A;  4NWJ A;  3NKM A;  1N2L A;  4LRB A;  1SMN A;  4ZG6 A;  3M8Z A;  5L0B A;  3M7V A;  2O3B A;  5LQQ A;  1SHN A;  1AJB A;  1HQA A;  2IUC B;  4QAX A;  1KH7 A;  2GSO A;  3M8Y A;  1ALJ A;  5C66 A;  1ALI A;  2W8D A;  1KHN A;  1G8T A;  2G9Y A;  4KAY A;  3T01 A;  1E2S P;  2GSU A;  4LRD A;  1FSU A;  3IDD A;  1P49 A;  1URA A;  1AJA A;  5GKP A;  1AUK A;  4UOO A;  1Y7A A;  1ED9 A;  1ALH A; 
#chains in the Genus database with same CATH topology
 1EQJ A;  3BDH A;  3MK0 A;  3M8W A;  1EW2 A;  1AJC A;  5TJ3 A;  4MY4 A;  4CXU A;  5DLW A;  5LRN A;  2W5S A;  1AJD A;  1ELZ A;  3TWZ A;  3NKO A;  1Y6V A;  3UN2 A;  2XGR A;  3UO0 A;  1ANI A;  2VQR A;  2W8S A;  2W5T A;  4MHX A;  1EW9 A;  4A1N A;  4GTY A;  2IUC A;  2QZU A;  5IJS A;  1B8J A;  3BDG B;  5LIA A;  3NKR A;  3BDG A;  4LR2 A;  4LRC A;  2GA3 A;  1KH4 A;  2W5X A;  4LR7 A;  3B5Q A;  2D1G A;  3UN5 A;  2IFY A;  5HRT A;  3OWV A;  1N2K A;  4GTZ A;  4CYR A;  4GTX A;  3SZZ A;  1E33 P;  4B56 A;  3Q3Q A;  4LQY A;  4FDJ A;  1KHK A;  4CYS A;  3ISM A;  4LR9 A;  4UOR A;  4CXK A;  3TX0 A;  5DLV A;  4UPK A;  4GTW A;  4QGO A;  4NWX A;  5EGE A;  2W5Q A;  2W5V A;  2GLQ A;  5L0E A;  1E1Z P;  4KAV A;  2XRG A;  5K4P A;  3SZY A;  3ED4 A;  2ANH A;  5EGH A;  1K7H A;  3T02 A;  3TG0 A;  5INH A;  4E3Y A;  1ELY A;  3IGY B;  4QH0 A;  3NKP A;  1QAE A;  4ZG9 A;  1EJJ A;  4QN0 A;  3OT9 A;  1ZM8 A;  4LRE A;  5LRM A;  3WAV A;  3A52 A;  3E2D A;  3DPC A;  4ZGA A;  4UPL A;  4MIV A;  3KD8 A;  4FDI A;  1E3C P;  5DLT A;  5GKC A;  3S5B A;  1KH9 A;  1HJK A;  3WBH A;  4KJD A;  5GOV A;  3WAW A;  4LR8 A;  2W5W A;  4TN0 A;  3CMR A;  2W5R A;  1KH5 A;  4KM4 A;  1ANJ A;  4YR1 A;  3NKQ A;  2XH3 A;  1ZED A;  4UPH A;  3T00 A;  1O99 A;  1SHQ A;  3WAX A;  2XR9 A;  2GSN A;  1QL0 A;  3IGZ B;  4UOP A;  4CXS A;  1EW8 A;  1ED8 A;  3MK1 A;  1EI6 A;  5AJ9 A;  3UN3 A;  3NVL A;  1ZEB A;  4ZG7 A;  4LRF A;  2RH6 A;  4N7T A;  1KHJ A;  4LRA A;  1O98 A;  3NKN A;  3UNY A;  1ELX A;  2ZKT A;  5GRR A;  1URB A;  1ZEF A;  3BDF A;  3LXQ A;  3MK2 A;  2X98 A;  5KXA A;  4KJG A;  1HDH A;  5IJQ A;  1KHL A;  4UPI A;  1ALK A;  3DYC A;  3WAY A;  5L0K A;  4NWJ A;  3NKM A;  1N2L A;  4LRB A;  1SMN A;  4ZG6 A;  3M8Z A;  5L0B A;  3M7V A;  2O3B A;  5LQQ A;  1SHN A;  1AJB A;  1HQA A;  2IUC B;  4QAX A;  1KH7 A;  2GSO A;  3M8Y A;  1ALJ A;  5C66 A;  1ALI A;  2W8D A;  1KHN A;  1G8T A;  2G9Y A;  4KAY A;  3T01 A;  1E2S P;  2GSU A;  4LRD A;  1FSU A;  3IDD A;  1P49 A;  1URA A;  1AJA A;  5GKP A;  1AUK A;  4UOO A;  1Y7A A;  1ED9 A;  1ALH A; 
#chains in the Genus database with same CATH homology
 1EQJ A;  3BDH A;  3MK0 A;  3M8W A;  1EW2 A;  1AJC A;  5TJ3 A;  4MY4 A;  4CXU A;  5DLW A;  5LRN A;  2W5S A;  1AJD A;  1ELZ A;  3TWZ A;  3NKO A;  1Y6V A;  3UN2 A;  2XGR A;  3UO0 A;  1ANI A;  2VQR A;  2W8S A;  2W5T A;  4MHX A;  1EW9 A;  4A1N A;  4GTY A;  2IUC A;  2QZU A;  5IJS A;  1B8J A;  3BDG B;  5LIA A;  3NKR A;  3BDG A;  4LR2 A;  4LRC A;  2GA3 A;  1KH4 A;  2W5X A;  4LR7 A;  3B5Q A;  2D1G A;  3UN5 A;  2IFY A;  5HRT A;  3OWV A;  1N2K A;  4GTZ A;  4CYR A;  4GTX A;  3SZZ A;  1E33 P;  4B56 A;  3Q3Q A;  4LQY A;  4FDJ A;  1KHK A;  4CYS A;  3ISM A;  4LR9 A;  4UOR A;  4CXK A;  3TX0 A;  5DLV A;  4UPK A;  4GTW A;  4QGO A;  4NWX A;  5EGE A;  2W5Q A;  2W5V A;  2GLQ A;  5L0E A;  1E1Z P;  4KAV A;  2XRG A;  5K4P A;  3SZY A;  3ED4 A;  2ANH A;  5EGH A;  1K7H A;  3T02 A;  3TG0 A;  5INH A;  4E3Y A;  1ELY A;  3IGY B;  4QH0 A;  3NKP A;  1QAE A;  4ZG9 A;  1EJJ A;  4QN0 A;  3OT9 A;  1ZM8 A;  4LRE A;  5LRM A;  3WAV A;  3A52 A;  3E2D A;  3DPC A;  4ZGA A;  4UPL A;  4MIV A;  3KD8 A;  4FDI A;  1E3C P;  5DLT A;  5GKC A;  3S5B A;  1KH9 A;  1HJK A;  3WBH A;  4KJD A;  5GOV A;  3WAW A;  4LR8 A;  2W5W A;  4TN0 A;  3CMR A;  2W5R A;  1KH5 A;  4KM4 A;  1ANJ A;  4YR1 A;  3NKQ A;  2XH3 A;  1ZED A;  4UPH A;  3T00 A;  1O99 A;  1SHQ A;  3WAX A;  2XR9 A;  2GSN A;  1QL0 A;  3IGZ B;  4UOP A;  4CXS A;  1EW8 A;  1ED8 A;  3MK1 A;  1EI6 A;  5AJ9 A;  3UN3 A;  3NVL A;  1ZEB A;  4ZG7 A;  4LRF A;  2RH6 A;  4N7T A;  1KHJ A;  4LRA A;  1O98 A;  3NKN A;  3UNY A;  1ELX A;  2ZKT A;  5GRR A;  1URB A;  1ZEF A;  3BDF A;  3LXQ A;  3MK2 A;  2X98 A;  5KXA A;  4KJG A;  1HDH A;  5IJQ A;  1KHL A;  4UPI A;  1ALK A;  3DYC A;  3WAY A;  5L0K A;  4NWJ A;  3NKM A;  1N2L A;  4LRB A;  1SMN A;  4ZG6 A;  3M8Z A;  5L0B A;  3M7V A;  2O3B A;  5LQQ A;  1SHN A;  1AJB A;  1HQA A;  2IUC B;  4QAX A;  1KH7 A;  2GSO A;  3M8Y A;  1ALJ A;  5C66 A;  1ALI A;  2W8D A;  1KHN A;  1G8T A;  2G9Y A;  4KAY A;  3T01 A;  1E2S P;  2GSU A;  4LRD A;  1FSU A;  3IDD A;  1P49 A;  1URA A;  1AJA A;  5GKP A;  1AUK A;  4UOO A;  1Y7A A;  1ED9 A;  1ALH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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