4ZG7A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 247
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
Knots found
sequence length
806
structure length
776
Chain Sequence
ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIAALTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
total genus 247
structure length 776
sequence length 806
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg7A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg7A03
3NKNA 1ALJA 1P49A 3WBHA 1EI6A 2W8SA 3IGZB 4KJGA 3BDHA 4QAXA 4ZG7A 4UPIA 4CXSA 1G8TA 5L0EA 1ZM8A 2W5WA 4GTXA 1Y7AA 4LRFA 3WAYA 2XGRA 1QAEA 4NWXA 3T02A 3UO0A 5C66A 3M7VA 3NKRA 2XH3A 3LXQA 3UN3A 1SHQA 5TJ3A 3WAXA 4CYRA 5DLTA 5IJSA 2GLQA 3UN2A 2IFYA 1KHKA 1HDHA 4GTZA 5LQQA 1E33P 1EQJA 1FSUA 1KHNA 1ALIA 3IGYB 2ZKTA 3MK2A 4LR2A 3BDFA 1KHLA 5IJQA 3A52A 1ALKA 3E2DA 1ANJA 3T00A 2W5SA 1HQAA 2W5RA 5EGHA 5L0BA 1K7HA 4TN0A 2D1GA 3BDGA 3ED4A 5LRNA 1ED9A 1ELXA 1KH7A 1URBA 3DYCA 1ZEDA 4B56A 1ALHA 5DLWA 4FDJA 1O98A 1EW9A 1ZEFA 2W5VA 4UPKA 3BDGB 3Q3QA 4KAVA 1KHJA 3IDDA 4UOPA 3TX0A 5GRRA 1N2LA 5INHA 3TWZA 4YR1A 2RH6A 3SZZA 1URAA 3M8WA 1AUKA 2ANHA 1SHNA 2GA3A 2W8DA 4LQYA 4QH0A 1SMNA 4LRAA 2IUCB 5GOVA 1Y6VA 1HJKA 3NKOA 1E3CP 3NKQA 3UN5A 3NKPA 4GTYA 2VQRA 4QGOA 3SZYA 2IUCA 2G9YA 1B8JA 2GSOA 4LR7A 2GSNA 3B5QA 4QN0A 3M8ZA 2X98A 2XRGA 4CXUA 4FDIA 3MK0A 3TG0A 4LR9A 4A1NA 1E2SP 5KXAA 5EGEA 3WAWA 4MHXA 2W5QA 1KH5A 5LIAA 1AJDA 3UNYA 3NVLA 1AJAA 5DLVA 1AJCA 2O3BA 1ELZA 5L0KA 3OT9A 5K4PA 3OWVA 4LREA 4UORA 4KJDA 5AJ9A 1QL0A 4LRBA 2GSUA 1ANIA 3DPCA 4GTWA 4UPHA 4KAYA 3M8YA 4LR8A 4LRDA 4ZG9A 4CYSA 3NKMA 4E3YA 4NWJA 4UOOA 4CXKA 2W5TA 1KH9A 4LRCA 2QZUA 1KH4A 1AJBA 3CMRA 4MIVA 1ELYA 3MK1A 1EW8A 1EW2A 1EJJA 4N7TA 4ZG6A 3ISMA 5HRTA 3T01A 4KM4A 1E1ZP 5GKPA 3KD8A 3S5BA 4UPLA 2W5XA 5LRMA 1ED8A 1N2KA 3WAVA 4ZGAA 1ZEBA 2XR9A 5GKCA 1O99A 4MY4A
chains in the Genus database with same CATH superfamily
3NKNA 1ALJA 1P49A 3WBHA 1EI6A 2W8SA 3IGZB 4KJGA 3BDHA 4QAXA 4ZG7A 4UPIA 4CXSA 1G8TA 5L0EA 1ZM8A 2W5WA 4GTXA 1Y7AA 4LRFA 3WAYA 2XGRA 1QAEA 4NWXA 3T02A 3UO0A 5C66A 3M7VA 3NKRA 2XH3A 3LXQA 3UN3A 1SHQA 5TJ3A 3WAXA 4CYRA 5DLTA 5IJSA 2GLQA 3UN2A 2IFYA 1KHKA 1HDHA 4GTZA 5LQQA 1E33P 1EQJA 1FSUA 1KHNA 1ALIA 3IGYB 2ZKTA 3MK2A 4LR2A 3BDFA 1KHLA 5IJQA 3A52A 1ALKA 3E2DA 1ANJA 3T00A 2W5SA 1HQAA 2W5RA 5EGHA 5L0BA 1K7HA 4TN0A 2D1GA 3BDGA 3ED4A 5LRNA 1ED9A 1ELXA 1KH7A 1URBA 3DYCA 1ZEDA 4B56A 1ALHA 5DLWA 4FDJA 1O98A 1EW9A 1ZEFA 2W5VA 4UPKA 3BDGB 3Q3QA 4KAVA 1KHJA 3IDDA 4UOPA 3TX0A 5GRRA 1N2LA 5INHA 3TWZA 4YR1A 2RH6A 3SZZA 1URAA 3M8WA 1AUKA 2ANHA 1SHNA 2GA3A 2W8DA 4LQYA 4QH0A 1SMNA 4LRAA 2IUCB 5GOVA 1Y6VA 1HJKA 3NKOA 1E3CP 3NKQA 3UN5A 3NKPA 4GTYA 2VQRA 4QGOA 3SZYA 2IUCA 2G9YA 1B8JA 2GSOA 4LR7A 2GSNA 3B5QA 4QN0A 3M8ZA 2X98A 2XRGA 4CXUA 4FDIA 3MK0A 3TG0A 4LR9A 4A1NA 1E2SP 5KXAA 5EGEA 3WAWA 4MHXA 2W5QA 1KH5A 5LIAA 1AJDA 3UNYA 3NVLA 1AJAA 5DLVA 1AJCA 2O3BA 1ELZA 5L0KA 3OT9A 5K4PA 3OWVA 4LREA 4UORA 4KJDA 5AJ9A 1QL0A 4LRBA 2GSUA 1ANIA 3DPCA 4GTWA 4UPHA 4KAYA 3M8YA 4LR8A 4LRDA 4ZG9A 4CYSA 3NKMA 4E3YA 4NWJA 4UOOA 4CXKA 2W5TA 1KH9A 4LRCA 2QZUA 1KH4A 1AJBA 3CMRA 4MIVA 1ELYA 3MK1A 1EW8A 1EW2A 1EJJA 4N7TA 4ZG6A 3ISMA 5HRTA 3T01A 4KM4A 1E1ZP 5GKPA 3KD8A 3S5BA 4UPLA 2W5XA 5LRMA 1ED8A 1N2KA 3WAVA 4ZGAA 1ZEBA 2XR9A 5GKCA 1O99A 4MY4A
chains in the Genus database with same CATH topology
3NKNA 1ALJA 1P49A 3WBHA 1EI6A 2W8SA 3IGZB 4KJGA 3BDHA 4QAXA 4ZG7A 4UPIA 4CXSA 1G8TA 5L0EA 1ZM8A 2W5WA 4GTXA 1Y7AA 4LRFA 3WAYA 2XGRA 1QAEA 4NWXA 3T02A 3UO0A 5C66A 3M7VA 3NKRA 2XH3A 3LXQA 3UN3A 1SHQA 5TJ3A 3WAXA 4CYRA 5DLTA 5IJSA 2GLQA 3UN2A 2IFYA 1KHKA 1HDHA 4GTZA 5LQQA 1E33P 1EQJA 1FSUA 1KHNA 1ALIA 3IGYB 2ZKTA 3MK2A 4LR2A 3BDFA 1KHLA 5IJQA 3A52A 1ALKA 3E2DA 1ANJA 3T00A 2W5SA 1HQAA 2W5RA 5EGHA 5L0BA 1K7HA 4TN0A 2D1GA 3BDGA 3ED4A 5LRNA 1ED9A 1ELXA 1KH7A 1URBA 3DYCA 1ZEDA 4B56A 1ALHA 5DLWA 4FDJA 1O98A 1EW9A 1ZEFA 2W5VA 4UPKA 3BDGB 3Q3QA 4KAVA 1KHJA 3IDDA 4UOPA 3TX0A 5GRRA 1N2LA 5INHA 3TWZA 4YR1A 2RH6A 3SZZA 1URAA 3M8WA 1AUKA 2ANHA 1SHNA 2GA3A 2W8DA 4LQYA 4QH0A 1SMNA 4LRAA 2IUCB 5GOVA 1Y6VA 1HJKA 3NKOA 1E3CP 3NKQA 3UN5A 3NKPA 4GTYA 2VQRA 4QGOA 3SZYA 2IUCA 2G9YA 1B8JA 2GSOA 4LR7A 2GSNA 3B5QA 4QN0A 3M8ZA 2X98A 2XRGA 4CXUA 4FDIA 3MK0A 3TG0A 4LR9A 4A1NA 1E2SP 5KXAA 5EGEA 3WAWA 4MHXA 2W5QA 1KH5A 5LIAA 1AJDA 3UNYA 3NVLA 1AJAA 5DLVA 1AJCA 2O3BA 1ELZA 5L0KA 3OT9A 5K4PA 3OWVA 4LREA 4UORA 4KJDA 5AJ9A 1QL0A 4LRBA 2GSUA 1ANIA 3DPCA 4GTWA 4UPHA 4KAYA 3M8YA 4LR8A 4LRDA 4ZG9A 4CYSA 3NKMA 4E3YA 4NWJA 4UOOA 4CXKA 2W5TA 1KH9A 4LRCA 2QZUA 1KH4A 1AJBA 3CMRA 4MIVA 1ELYA 3MK1A 1EW8A 1EW2A 1EJJA 4N7TA 4ZG6A 3ISMA 5HRTA 3T01A 4KM4A 1E1ZP 5GKPA 3KD8A 3S5BA 4UPLA 2W5XA 5LRMA 1ED8A 1N2KA 3WAVA 4ZGAA 1ZEBA 2XR9A 5GKCA 1O99A 4MY4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NKN A;  1ALJ A;  1P49 A;  3WBH A;  1EI6 A;  2W8S A;  3IGZ B;  4KJG A;  3BDH A;  4QAX A;  4ZG7 A;  4UPI A;  4CXS A;  1G8T A;  5L0E A;  1ZM8 A;  2W5W A;  4GTX A;  1Y7A A;  4LRF A;  3WAY A;  2XGR A;  1QAE A;  4NWX A;  3T02 A;  3UO0 A;  5C66 A;  3M7V A;  3NKR A;  2XH3 A;  3LXQ A;  3UN3 A;  1SHQ A;  5TJ3 A;  3WAX A;  4CYR A;  5DLT A;  5IJS A;  2GLQ A;  3UN2 A;  2IFY A;  1KHK A;  1HDH A;  4GTZ A;  5LQQ A;  1E33 P;  1EQJ A;  1FSU A;  1KHN A;  1ALI A;  3IGY B;  2ZKT A;  3MK2 A;  4LR2 A;  3BDF A;  1KHL A;  5IJQ A;  3A52 A;  1ALK A;  3E2D A;  1ANJ A;  3T00 A;  2W5S A;  1HQA A;  2W5R A;  5EGH A;  5L0B A;  1K7H A;  4TN0 A;  2D1G A;  3BDG A;  3ED4 A;  5LRN A;  1ED9 A;  1ELX A;  1KH7 A;  1URB A;  3DYC A;  1ZED A;  4B56 A;  1ALH A;  5DLW A;  4FDJ A;  1O98 A;  1EW9 A;  1ZEF A;  2W5V A;  4UPK A;  3BDG B;  3Q3Q A;  4KAV A;  1KHJ A;  3IDD A;  4UOP A;  3TX0 A;  5GRR A;  1N2L A;  5INH A;  3TWZ A;  4YR1 A;  2RH6 A;  3SZZ A;  1URA A;  3M8W A;  1AUK A;  2ANH A;  1SHN A;  2GA3 A;  2W8D A;  4LQY A;  4QH0 A;  1SMN A;  4LRA A;  2IUC B;  5GOV A;  1Y6V A;  1HJK A;  3NKO A;  1E3C P;  3NKQ A;  3UN5 A;  3NKP A;  4GTY A;  2VQR A;  4QGO A;  3SZY A;  2IUC A;  2G9Y A;  1B8J A;  2GSO A;  4LR7 A;  2GSN A;  3B5Q A;  4QN0 A;  3M8Z A;  2X98 A;  2XRG A;  4CXU A;  4FDI A;  3MK0 A;  3TG0 A;  4LR9 A;  4A1N A;  1E2S P;  5KXA A;  5EGE A;  3WAW A;  4MHX A;  2W5Q A;  1KH5 A;  5LIA A;  1AJD A;  3UNY A;  3NVL A;  1AJA A;  5DLV A;  1AJC A;  2O3B A;  1ELZ A;  5L0K A;  3OT9 A;  5K4P A;  3OWV A;  4LRE A;  4UOR A;  4KJD A;  5AJ9 A;  1QL0 A;  4LRB A;  2GSU A;  1ANI A;  3DPC A;  4GTW A;  4UPH A;  4KAY A;  3M8Y A;  4LR8 A;  4LRD A;  4ZG9 A;  4CYS A;  3NKM A;  4E3Y A;  4NWJ A;  4UOO A;  4CXK A;  2W5T A;  1KH9 A;  4LRC A;  2QZU A;  1KH4 A;  1AJB A;  3CMR A;  4MIV A;  1ELY A;  3MK1 A;  1EW8 A;  1EW2 A;  1EJJ A;  4N7T A;  4ZG6 A;  3ISM A;  5HRT A;  3T01 A;  4KM4 A;  1E1Z P;  5GKP A;  3KD8 A;  3S5B A;  4UPL A;  2W5X A;  5LRM A;  1ED8 A;  1N2K A;  3WAV A;  4ZGA A;  1ZEB A;  2XR9 A;  5GKC A;  1O99 A;  4MY4 A; 
#chains in the Genus database with same CATH topology
 3NKN A;  1ALJ A;  1P49 A;  3WBH A;  1EI6 A;  2W8S A;  3IGZ B;  4KJG A;  3BDH A;  4QAX A;  4ZG7 A;  4UPI A;  4CXS A;  1G8T A;  5L0E A;  1ZM8 A;  2W5W A;  4GTX A;  1Y7A A;  4LRF A;  3WAY A;  2XGR A;  1QAE A;  4NWX A;  3T02 A;  3UO0 A;  5C66 A;  3M7V A;  3NKR A;  2XH3 A;  3LXQ A;  3UN3 A;  1SHQ A;  5TJ3 A;  3WAX A;  4CYR A;  5DLT A;  5IJS A;  2GLQ A;  3UN2 A;  2IFY A;  1KHK A;  1HDH A;  4GTZ A;  5LQQ A;  1E33 P;  1EQJ A;  1FSU A;  1KHN A;  1ALI A;  3IGY B;  2ZKT A;  3MK2 A;  4LR2 A;  3BDF A;  1KHL A;  5IJQ A;  3A52 A;  1ALK A;  3E2D A;  1ANJ A;  3T00 A;  2W5S A;  1HQA A;  2W5R A;  5EGH A;  5L0B A;  1K7H A;  4TN0 A;  2D1G A;  3BDG A;  3ED4 A;  5LRN A;  1ED9 A;  1ELX A;  1KH7 A;  1URB A;  3DYC A;  1ZED A;  4B56 A;  1ALH A;  5DLW A;  4FDJ A;  1O98 A;  1EW9 A;  1ZEF A;  2W5V A;  4UPK A;  3BDG B;  3Q3Q A;  4KAV A;  1KHJ A;  3IDD A;  4UOP A;  3TX0 A;  5GRR A;  1N2L A;  5INH A;  3TWZ A;  4YR1 A;  2RH6 A;  3SZZ A;  1URA A;  3M8W A;  1AUK A;  2ANH A;  1SHN A;  2GA3 A;  2W8D A;  4LQY A;  4QH0 A;  1SMN A;  4LRA A;  2IUC B;  5GOV A;  1Y6V A;  1HJK A;  3NKO A;  1E3C P;  3NKQ A;  3UN5 A;  3NKP A;  4GTY A;  2VQR A;  4QGO A;  3SZY A;  2IUC A;  2G9Y A;  1B8J A;  2GSO A;  4LR7 A;  2GSN A;  3B5Q A;  4QN0 A;  3M8Z A;  2X98 A;  2XRG A;  4CXU A;  4FDI A;  3MK0 A;  3TG0 A;  4LR9 A;  4A1N A;  1E2S P;  5KXA A;  5EGE A;  3WAW A;  4MHX A;  2W5Q A;  1KH5 A;  5LIA A;  1AJD A;  3UNY A;  3NVL A;  1AJA A;  5DLV A;  1AJC A;  2O3B A;  1ELZ A;  5L0K A;  3OT9 A;  5K4P A;  3OWV A;  4LRE A;  4UOR A;  4KJD A;  5AJ9 A;  1QL0 A;  4LRB A;  2GSU A;  1ANI A;  3DPC A;  4GTW A;  4UPH A;  4KAY A;  3M8Y A;  4LR8 A;  4LRD A;  4ZG9 A;  4CYS A;  3NKM A;  4E3Y A;  4NWJ A;  4UOO A;  4CXK A;  2W5T A;  1KH9 A;  4LRC A;  2QZU A;  1KH4 A;  1AJB A;  3CMR A;  4MIV A;  1ELY A;  3MK1 A;  1EW8 A;  1EW2 A;  1EJJ A;  4N7T A;  4ZG6 A;  3ISM A;  5HRT A;  3T01 A;  4KM4 A;  1E1Z P;  5GKP A;  3KD8 A;  3S5B A;  4UPL A;  2W5X A;  5LRM A;  1ED8 A;  1N2K A;  3WAV A;  4ZGA A;  1ZEB A;  2XR9 A;  5GKC A;  1O99 A;  4MY4 A; 
#chains in the Genus database with same CATH homology
 3NKN A;  1ALJ A;  1P49 A;  3WBH A;  1EI6 A;  2W8S A;  3IGZ B;  4KJG A;  3BDH A;  4QAX A;  4ZG7 A;  4UPI A;  4CXS A;  1G8T A;  5L0E A;  1ZM8 A;  2W5W A;  4GTX A;  1Y7A A;  4LRF A;  3WAY A;  2XGR A;  1QAE A;  4NWX A;  3T02 A;  3UO0 A;  5C66 A;  3M7V A;  3NKR A;  2XH3 A;  3LXQ A;  3UN3 A;  1SHQ A;  5TJ3 A;  3WAX A;  4CYR A;  5DLT A;  5IJS A;  2GLQ A;  3UN2 A;  2IFY A;  1KHK A;  1HDH A;  4GTZ A;  5LQQ A;  1E33 P;  1EQJ A;  1FSU A;  1KHN A;  1ALI A;  3IGY B;  2ZKT A;  3MK2 A;  4LR2 A;  3BDF A;  1KHL A;  5IJQ A;  3A52 A;  1ALK A;  3E2D A;  1ANJ A;  3T00 A;  2W5S A;  1HQA A;  2W5R A;  5EGH A;  5L0B A;  1K7H A;  4TN0 A;  2D1G A;  3BDG A;  3ED4 A;  5LRN A;  1ED9 A;  1ELX A;  1KH7 A;  1URB A;  3DYC A;  1ZED A;  4B56 A;  1ALH A;  5DLW A;  4FDJ A;  1O98 A;  1EW9 A;  1ZEF A;  2W5V A;  4UPK A;  3BDG B;  3Q3Q A;  4KAV A;  1KHJ A;  3IDD A;  4UOP A;  3TX0 A;  5GRR A;  1N2L A;  5INH A;  3TWZ A;  4YR1 A;  2RH6 A;  3SZZ A;  1URA A;  3M8W A;  1AUK A;  2ANH A;  1SHN A;  2GA3 A;  2W8D A;  4LQY A;  4QH0 A;  1SMN A;  4LRA A;  2IUC B;  5GOV A;  1Y6V A;  1HJK A;  3NKO A;  1E3C P;  3NKQ A;  3UN5 A;  3NKP A;  4GTY A;  2VQR A;  4QGO A;  3SZY A;  2IUC A;  2G9Y A;  1B8J A;  2GSO A;  4LR7 A;  2GSN A;  3B5Q A;  4QN0 A;  3M8Z A;  2X98 A;  2XRG A;  4CXU A;  4FDI A;  3MK0 A;  3TG0 A;  4LR9 A;  4A1N A;  1E2S P;  5KXA A;  5EGE A;  3WAW A;  4MHX A;  2W5Q A;  1KH5 A;  5LIA A;  1AJD A;  3UNY A;  3NVL A;  1AJA A;  5DLV A;  1AJC A;  2O3B A;  1ELZ A;  5L0K A;  3OT9 A;  5K4P A;  3OWV A;  4LRE A;  4UOR A;  4KJD A;  5AJ9 A;  1QL0 A;  4LRB A;  2GSU A;  1ANI A;  3DPC A;  4GTW A;  4UPH A;  4KAY A;  3M8Y A;  4LR8 A;  4LRD A;  4ZG9 A;  4CYS A;  3NKM A;  4E3Y A;  4NWJ A;  4UOO A;  4CXK A;  2W5T A;  1KH9 A;  4LRC A;  2QZU A;  1KH4 A;  1AJB A;  3CMR A;  4MIV A;  1ELY A;  3MK1 A;  1EW8 A;  1EW2 A;  1EJJ A;  4N7T A;  4ZG6 A;  3ISM A;  5HRT A;  3T01 A;  4KM4 A;  1E1Z P;  5GKP A;  3KD8 A;  3S5B A;  4UPL A;  2W5X A;  5LRM A;  1ED8 A;  1N2K A;  3WAV A;  4ZGA A;  1ZEB A;  2XR9 A;  5GKC A;  1O99 A;  4MY4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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