4ZG7A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 247
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
Knots found
sequence length
806
structure length
776
Chain Sequence
b'ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIAALTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 247
structure length 776
sequence length 806
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg7A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg7A03
5L0BA 3OWVA 1KHJA 4NWXA 1HDHA 3M8ZA 1KH4A 4QH0A 3B5QA 4KM4A 1ALJA 4CXKA 1ED8A 4UPKA 4ZG7A 3ISMA 3NKQA 5IJQA 1KH7A 4LRBA 3T01A 3T02A 1KHKA 4KJGA 1ELXA 2W5RA 4UORA 1AJBA 4N7TA 3TX0A 5GRRA 4LRAA 5C66A 1EI6A 3NKPA 1O99A 4UOPA 2IFYA 1ANIA 3BDFA 4LR7A 1E3CP 4ZG6A 4TN0A 2GSOA 1E2SP 3IGYB 2GSNA 4GTXA 2XH3A 3NKNA 3WAVA 3TWZA 2XGRA 4LR9A 5TJ3A 4GTZA 4UPLA 3NKRA 1ALKA 5GOVA 2W5VA 1KH5A 4NWJA 1ZEBA 3OT9A 1ALHA 4MY4A 3UN3A 2XRGA 4LRCA 1AJCA 3MK0A 3SZYA 3IGZB 3KD8A 1O98A 2G9YA 5DLTA 4LR2A 1E1ZP 1EJJA 2XR9A 4CYSA 3NKMA 2D1GA 1ZM8A 1ED9A 3S5BA 1SHNA 2GLQA 3T00A 5LQQA 2W5SA 3E2DA 1P49A 1EW2A 4UOOA 4FDIA 5IJSA 5KXAA 1E33P 1K7HA 4LR8A 4MHXA 2ANHA 3M8WA 3MK2A 3MK1A 2O3BA 4LRFA 4QGOA 5GKPA 1KH9A 2X98A 3WAYA 3UN2A 1N2KA 3DPCA 1KHNA 4YR1A 4UPHA 5INHA 1QL0A 3M8YA 2W8SA 2ZKTA 3NVLA 3CMRA 4FDJA 3WBHA 4MIVA 1KHLA 2W5QA 5EGEA 5LRMA 1EW8A 2W8DA 3DYCA 1Y7AA 3BDGA 1EW9A 1URBA 2VQRA 2IUCA 1N2LA 5L0EA 4B56A 1Y6VA 3ED4A 1ZEDA 4ZG9A 1AUKA 2W5TA 2GA3A 4KAYA 5GKCA 5DLVA 5HRTA 4LQYA 5EGHA 5LRNA 1QAEA 4ZGAA 1EQJA 3LXQA 1ELYA 1URAA 4GTYA 1AJAA 4LRDA 5DLWA 3A52A 4UPIA 1AJDA 4A1NA 3WAXA 2W5WA 3SZZA 3UN5A 4GTWA 1ZEFA 3BDGB 5LIAA 1ALIA 4E3YA 2IUCB 4KAVA 1SHQA 2GSUA 4LREA 3M7VA 4QAXA 5K4PA 4CXUA 1SMNA 2QZUA 1ANJA 3NKOA 4KJDA 5AJ9A 3UNYA 5L0KA 4CXSA 1HQAA 3IDDA 1G8TA 4CYRA 3Q3QA 3TG0A 3WAWA 1HJKA 1B8JA 1FSUA 3UO0A 2W5XA 3BDHA 1ELZA 4QN0A 2RH6A
chains in the Genus database with same CATH superfamily
5L0BA 3OWVA 1KHJA 4NWXA 1HDHA 3M8ZA 1KH4A 4QH0A 3B5QA 4KM4A 1ALJA 4CXKA 1ED8A 4UPKA 4ZG7A 3ISMA 3NKQA 5IJQA 1KH7A 4LRBA 3T01A 3T02A 1KHKA 4KJGA 1ELXA 2W5RA 4UORA 1AJBA 4N7TA 3TX0A 5GRRA 4LRAA 5C66A 1EI6A 3NKPA 1O99A 4UOPA 2IFYA 1ANIA 3BDFA 4LR7A 1E3CP 4ZG6A 4TN0A 2GSOA 1E2SP 3IGYB 2GSNA 4GTXA 2XH3A 3NKNA 3WAVA 3TWZA 2XGRA 4LR9A 5TJ3A 4GTZA 4UPLA 3NKRA 1ALKA 5GOVA 2W5VA 1KH5A 4NWJA 1ZEBA 3OT9A 1ALHA 4MY4A 3UN3A 2XRGA 4LRCA 1AJCA 3MK0A 3SZYA 3IGZB 3KD8A 1O98A 2G9YA 5DLTA 4LR2A 1E1ZP 1EJJA 2XR9A 4CYSA 3NKMA 2D1GA 1ZM8A 1ED9A 3S5BA 1SHNA 2GLQA 3T00A 5LQQA 2W5SA 3E2DA 1P49A 1EW2A 4UOOA 4FDIA 5IJSA 5KXAA 1E33P 1K7HA 4LR8A 4MHXA 2ANHA 3M8WA 3MK2A 3MK1A 2O3BA 4LRFA 4QGOA 5GKPA 1KH9A 2X98A 3WAYA 3UN2A 1N2KA 3DPCA 1KHNA 4YR1A 4UPHA 5INHA 1QL0A 3M8YA 2W8SA 2ZKTA 3NVLA 3CMRA 4FDJA 3WBHA 4MIVA 1KHLA 2W5QA 5EGEA 5LRMA 1EW8A 2W8DA 3DYCA 1Y7AA 3BDGA 1EW9A 1URBA 2VQRA 2IUCA 1N2LA 5L0EA 4B56A 1Y6VA 3ED4A 1ZEDA 4ZG9A 1AUKA 2W5TA 2GA3A 4KAYA 5GKCA 5DLVA 5HRTA 4LQYA 5EGHA 5LRNA 1QAEA 4ZGAA 1EQJA 3LXQA 1ELYA 1URAA 4GTYA 1AJAA 4LRDA 5DLWA 3A52A 4UPIA 1AJDA 4A1NA 3WAXA 2W5WA 3SZZA 3UN5A 4GTWA 1ZEFA 3BDGB 5LIAA 1ALIA 4E3YA 2IUCB 4KAVA 1SHQA 2GSUA 4LREA 3M7VA 4QAXA 5K4PA 4CXUA 1SMNA 2QZUA 1ANJA 3NKOA 4KJDA 5AJ9A 3UNYA 5L0KA 4CXSA 1HQAA 3IDDA 1G8TA 4CYRA 3Q3QA 3TG0A 3WAWA 1HJKA 1B8JA 1FSUA 3UO0A 2W5XA 3BDHA 1ELZA 4QN0A 2RH6A
chains in the Genus database with same CATH topology
5L0BA 3OWVA 1KHJA 4NWXA 1HDHA 3M8ZA 1KH4A 4QH0A 3B5QA 4KM4A 1ALJA 4CXKA 1ED8A 4UPKA 4ZG7A 3ISMA 3NKQA 5IJQA 1KH7A 4LRBA 3T01A 3T02A 1KHKA 4KJGA 1ELXA 2W5RA 4UORA 1AJBA 4N7TA 3TX0A 5GRRA 4LRAA 5C66A 1EI6A 3NKPA 1O99A 4UOPA 2IFYA 1ANIA 3BDFA 4LR7A 1E3CP 4ZG6A 4TN0A 2GSOA 1E2SP 3IGYB 2GSNA 4GTXA 2XH3A 3NKNA 3WAVA 3TWZA 2XGRA 4LR9A 5TJ3A 4GTZA 4UPLA 3NKRA 1ALKA 5GOVA 2W5VA 1KH5A 4NWJA 1ZEBA 3OT9A 1ALHA 4MY4A 3UN3A 2XRGA 4LRCA 1AJCA 3MK0A 3SZYA 3IGZB 3KD8A 1O98A 2G9YA 5DLTA 4LR2A 1E1ZP 1EJJA 2XR9A 4CYSA 3NKMA 2D1GA 1ZM8A 1ED9A 3S5BA 1SHNA 2GLQA 3T00A 5LQQA 2W5SA 3E2DA 1P49A 1EW2A 4UOOA 4FDIA 5IJSA 5KXAA 1E33P 1K7HA 4LR8A 4MHXA 2ANHA 3M8WA 3MK2A 3MK1A 2O3BA 4LRFA 4QGOA 5GKPA 1KH9A 2X98A 3WAYA 3UN2A 1N2KA 3DPCA 1KHNA 4YR1A 4UPHA 5INHA 1QL0A 3M8YA 2W8SA 2ZKTA 3NVLA 3CMRA 4FDJA 3WBHA 4MIVA 1KHLA 2W5QA 5EGEA 5LRMA 1EW8A 2W8DA 3DYCA 1Y7AA 3BDGA 1EW9A 1URBA 2VQRA 2IUCA 1N2LA 5L0EA 4B56A 1Y6VA 3ED4A 1ZEDA 4ZG9A 1AUKA 2W5TA 2GA3A 4KAYA 5GKCA 5DLVA 5HRTA 4LQYA 5EGHA 5LRNA 1QAEA 4ZGAA 1EQJA 3LXQA 1ELYA 1URAA 4GTYA 1AJAA 4LRDA 5DLWA 3A52A 4UPIA 1AJDA 4A1NA 3WAXA 2W5WA 3SZZA 3UN5A 4GTWA 1ZEFA 3BDGB 5LIAA 1ALIA 4E3YA 2IUCB 4KAVA 1SHQA 2GSUA 4LREA 3M7VA 4QAXA 5K4PA 4CXUA 1SMNA 2QZUA 1ANJA 3NKOA 4KJDA 5AJ9A 3UNYA 5L0KA 4CXSA 1HQAA 3IDDA 1G8TA 4CYRA 3Q3QA 3TG0A 3WAWA 1HJKA 1B8JA 1FSUA 3UO0A 2W5XA 3BDHA 1ELZA 4QN0A 2RH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L0B A;  3OWV A;  1KHJ A;  4NWX A;  1HDH A;  3M8Z A;  1KH4 A;  4QH0 A;  3B5Q A;  4KM4 A;  1ALJ A;  4CXK A;  1ED8 A;  4UPK A;  4ZG7 A;  3ISM A;  3NKQ A;  5IJQ A;  1KH7 A;  4LRB A;  3T01 A;  3T02 A;  1KHK A;  4KJG A;  1ELX A;  2W5R A;  4UOR A;  1AJB A;  4N7T A;  3TX0 A;  5GRR A;  4LRA A;  5C66 A;  1EI6 A;  3NKP A;  1O99 A;  4UOP A;  2IFY A;  1ANI A;  3BDF A;  4LR7 A;  1E3C P;  4ZG6 A;  4TN0 A;  2GSO A;  1E2S P;  3IGY B;  2GSN A;  4GTX A;  2XH3 A;  3NKN A;  3WAV A;  3TWZ A;  2XGR A;  4LR9 A;  5TJ3 A;  4GTZ A;  4UPL A;  3NKR A;  1ALK A;  5GOV A;  2W5V A;  1KH5 A;  4NWJ A;  1ZEB A;  3OT9 A;  1ALH A;  4MY4 A;  3UN3 A;  2XRG A;  4LRC A;  1AJC A;  3MK0 A;  3SZY A;  3IGZ B;  3KD8 A;  1O98 A;  2G9Y A;  5DLT A;  4LR2 A;  1E1Z P;  1EJJ A;  2XR9 A;  4CYS A;  3NKM A;  2D1G A;  1ZM8 A;  1ED9 A;  3S5B A;  1SHN A;  2GLQ A;  3T00 A;  5LQQ A;  2W5S A;  3E2D A;  1P49 A;  1EW2 A;  4UOO A;  4FDI A;  5IJS A;  5KXA A;  1E33 P;  1K7H A;  4LR8 A;  4MHX A;  2ANH A;  3M8W A;  3MK2 A;  3MK1 A;  2O3B A;  4LRF A;  4QGO A;  5GKP A;  1KH9 A;  2X98 A;  3WAY A;  3UN2 A;  1N2K A;  3DPC A;  1KHN A;  4YR1 A;  4UPH A;  5INH A;  1QL0 A;  3M8Y A;  2W8S A;  2ZKT A;  3NVL A;  3CMR A;  4FDJ A;  3WBH A;  4MIV A;  1KHL A;  2W5Q A;  5EGE A;  5LRM A;  1EW8 A;  2W8D A;  3DYC A;  1Y7A A;  3BDG A;  1EW9 A;  1URB A;  2VQR A;  2IUC A;  1N2L A;  5L0E A;  4B56 A;  1Y6V A;  3ED4 A;  1ZED A;  4ZG9 A;  1AUK A;  2W5T A;  2GA3 A;  4KAY A;  5GKC A;  5DLV A;  5HRT A;  4LQY A;  5EGH A;  5LRN A;  1QAE A;  4ZGA A;  1EQJ A;  3LXQ A;  1ELY A;  1URA A;  4GTY A;  1AJA A;  4LRD A;  5DLW A;  3A52 A;  4UPI A;  1AJD A;  4A1N A;  3WAX A;  2W5W A;  3SZZ A;  3UN5 A;  4GTW A;  1ZEF A;  3BDG B;  5LIA A;  1ALI A;  4E3Y A;  2IUC B;  4KAV A;  1SHQ A;  2GSU A;  4LRE A;  3M7V A;  4QAX A;  5K4P A;  4CXU A;  1SMN A;  2QZU A;  1ANJ A;  3NKO A;  4KJD A;  5AJ9 A;  3UNY A;  5L0K A;  4CXS A;  1HQA A;  3IDD A;  1G8T A;  4CYR A;  3Q3Q A;  3TG0 A;  3WAW A;  1HJK A;  1B8J A;  1FSU A;  3UO0 A;  2W5X A;  3BDH A;  1ELZ A;  4QN0 A;  2RH6 A; 
#chains in the Genus database with same CATH topology
 5L0B A;  3OWV A;  1KHJ A;  4NWX A;  1HDH A;  3M8Z A;  1KH4 A;  4QH0 A;  3B5Q A;  4KM4 A;  1ALJ A;  4CXK A;  1ED8 A;  4UPK A;  4ZG7 A;  3ISM A;  3NKQ A;  5IJQ A;  1KH7 A;  4LRB A;  3T01 A;  3T02 A;  1KHK A;  4KJG A;  1ELX A;  2W5R A;  4UOR A;  1AJB A;  4N7T A;  3TX0 A;  5GRR A;  4LRA A;  5C66 A;  1EI6 A;  3NKP A;  1O99 A;  4UOP A;  2IFY A;  1ANI A;  3BDF A;  4LR7 A;  1E3C P;  4ZG6 A;  4TN0 A;  2GSO A;  1E2S P;  3IGY B;  2GSN A;  4GTX A;  2XH3 A;  3NKN A;  3WAV A;  3TWZ A;  2XGR A;  4LR9 A;  5TJ3 A;  4GTZ A;  4UPL A;  3NKR A;  1ALK A;  5GOV A;  2W5V A;  1KH5 A;  4NWJ A;  1ZEB A;  3OT9 A;  1ALH A;  4MY4 A;  3UN3 A;  2XRG A;  4LRC A;  1AJC A;  3MK0 A;  3SZY A;  3IGZ B;  3KD8 A;  1O98 A;  2G9Y A;  5DLT A;  4LR2 A;  1E1Z P;  1EJJ A;  2XR9 A;  4CYS A;  3NKM A;  2D1G A;  1ZM8 A;  1ED9 A;  3S5B A;  1SHN A;  2GLQ A;  3T00 A;  5LQQ A;  2W5S A;  3E2D A;  1P49 A;  1EW2 A;  4UOO A;  4FDI A;  5IJS A;  5KXA A;  1E33 P;  1K7H A;  4LR8 A;  4MHX A;  2ANH A;  3M8W A;  3MK2 A;  3MK1 A;  2O3B A;  4LRF A;  4QGO A;  5GKP A;  1KH9 A;  2X98 A;  3WAY A;  3UN2 A;  1N2K A;  3DPC A;  1KHN A;  4YR1 A;  4UPH A;  5INH A;  1QL0 A;  3M8Y A;  2W8S A;  2ZKT A;  3NVL A;  3CMR A;  4FDJ A;  3WBH A;  4MIV A;  1KHL A;  2W5Q A;  5EGE A;  5LRM A;  1EW8 A;  2W8D A;  3DYC A;  1Y7A A;  3BDG A;  1EW9 A;  1URB A;  2VQR A;  2IUC A;  1N2L A;  5L0E A;  4B56 A;  1Y6V A;  3ED4 A;  1ZED A;  4ZG9 A;  1AUK A;  2W5T A;  2GA3 A;  4KAY A;  5GKC A;  5DLV A;  5HRT A;  4LQY A;  5EGH A;  5LRN A;  1QAE A;  4ZGA A;  1EQJ A;  3LXQ A;  1ELY A;  1URA A;  4GTY A;  1AJA A;  4LRD A;  5DLW A;  3A52 A;  4UPI A;  1AJD A;  4A1N A;  3WAX A;  2W5W A;  3SZZ A;  3UN5 A;  4GTW A;  1ZEF A;  3BDG B;  5LIA A;  1ALI A;  4E3Y A;  2IUC B;  4KAV A;  1SHQ A;  2GSU A;  4LRE A;  3M7V A;  4QAX A;  5K4P A;  4CXU A;  1SMN A;  2QZU A;  1ANJ A;  3NKO A;  4KJD A;  5AJ9 A;  3UNY A;  5L0K A;  4CXS A;  1HQA A;  3IDD A;  1G8T A;  4CYR A;  3Q3Q A;  3TG0 A;  3WAW A;  1HJK A;  1B8J A;  1FSU A;  3UO0 A;  2W5X A;  3BDH A;  1ELZ A;  4QN0 A;  2RH6 A; 
#chains in the Genus database with same CATH homology
 5L0B A;  3OWV A;  1KHJ A;  4NWX A;  1HDH A;  3M8Z A;  1KH4 A;  4QH0 A;  3B5Q A;  4KM4 A;  1ALJ A;  4CXK A;  1ED8 A;  4UPK A;  4ZG7 A;  3ISM A;  3NKQ A;  5IJQ A;  1KH7 A;  4LRB A;  3T01 A;  3T02 A;  1KHK A;  4KJG A;  1ELX A;  2W5R A;  4UOR A;  1AJB A;  4N7T A;  3TX0 A;  5GRR A;  4LRA A;  5C66 A;  1EI6 A;  3NKP A;  1O99 A;  4UOP A;  2IFY A;  1ANI A;  3BDF A;  4LR7 A;  1E3C P;  4ZG6 A;  4TN0 A;  2GSO A;  1E2S P;  3IGY B;  2GSN A;  4GTX A;  2XH3 A;  3NKN A;  3WAV A;  3TWZ A;  2XGR A;  4LR9 A;  5TJ3 A;  4GTZ A;  4UPL A;  3NKR A;  1ALK A;  5GOV A;  2W5V A;  1KH5 A;  4NWJ A;  1ZEB A;  3OT9 A;  1ALH A;  4MY4 A;  3UN3 A;  2XRG A;  4LRC A;  1AJC A;  3MK0 A;  3SZY A;  3IGZ B;  3KD8 A;  1O98 A;  2G9Y A;  5DLT A;  4LR2 A;  1E1Z P;  1EJJ A;  2XR9 A;  4CYS A;  3NKM A;  2D1G A;  1ZM8 A;  1ED9 A;  3S5B A;  1SHN A;  2GLQ A;  3T00 A;  5LQQ A;  2W5S A;  3E2D A;  1P49 A;  1EW2 A;  4UOO A;  4FDI A;  5IJS A;  5KXA A;  1E33 P;  1K7H A;  4LR8 A;  4MHX A;  2ANH A;  3M8W A;  3MK2 A;  3MK1 A;  2O3B A;  4LRF A;  4QGO A;  5GKP A;  1KH9 A;  2X98 A;  3WAY A;  3UN2 A;  1N2K A;  3DPC A;  1KHN A;  4YR1 A;  4UPH A;  5INH A;  1QL0 A;  3M8Y A;  2W8S A;  2ZKT A;  3NVL A;  3CMR A;  4FDJ A;  3WBH A;  4MIV A;  1KHL A;  2W5Q A;  5EGE A;  5LRM A;  1EW8 A;  2W8D A;  3DYC A;  1Y7A A;  3BDG A;  1EW9 A;  1URB A;  2VQR A;  2IUC A;  1N2L A;  5L0E A;  4B56 A;  1Y6V A;  3ED4 A;  1ZED A;  4ZG9 A;  1AUK A;  2W5T A;  2GA3 A;  4KAY A;  5GKC A;  5DLV A;  5HRT A;  4LQY A;  5EGH A;  5LRN A;  1QAE A;  4ZGA A;  1EQJ A;  3LXQ A;  1ELY A;  1URA A;  4GTY A;  1AJA A;  4LRD A;  5DLW A;  3A52 A;  4UPI A;  1AJD A;  4A1N A;  3WAX A;  2W5W A;  3SZZ A;  3UN5 A;  4GTW A;  1ZEF A;  3BDG B;  5LIA A;  1ALI A;  4E3Y A;  2IUC B;  4KAV A;  1SHQ A;  2GSU A;  4LRE A;  3M7V A;  4QAX A;  5K4P A;  4CXU A;  1SMN A;  2QZU A;  1ANJ A;  3NKO A;  4KJD A;  5AJ9 A;  3UNY A;  5L0K A;  4CXS A;  1HQA A;  3IDD A;  1G8T A;  4CYR A;  3Q3Q A;  3TG0 A;  3WAW A;  1HJK A;  1B8J A;  1FSU A;  3UO0 A;  2W5X A;  3BDH A;  1ELZ A;  4QN0 A;  2RH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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