3ALQR

Crystal structure of tnf-tnfr2 complex
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
162
structure length
162
Chain Sequence
TCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution of the Structure of the TNF-TNFR2 Complex
pubmed doi rcsb
molecule keywords Tumor necrosis factor
molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
total genus 25
structure length 162
sequence length 162
chains with identical sequence S, T, U, V, W
ec nomenclature
pdb deposition date 2010-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3alqR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3alqR01
3MI8D 2HEYR 3QD6R 3QBQB 1DU3A 5IHLA 3MHDD 4KGGC 5CIRE 4YN0A 1SG1X 3U3QA 3K51B 3QO4A 3MBWA 1TNRR 3THMF 1JMAB 1D4VA 4KGQC 4BK5A 5DMJA 4FHQA 3BUKC 3TJEF 4OD2S 5L36B 4I9XC 2AW2B 1D0GR 4N90R 3U3SA 3FL7A 4E4DR 3WVTA 3X3FA 4RSUD 2HEVR 3ALQR 4GIQR 1FT4A 2UWIA 1ZA3R 3URFZ 3IJ2X 4MSVB 4BK4A 4MXWR 3ME2R 3U3TA 5BNQR 1EXTA 2X10A 4M4PA 3U3VA 2H9GR 4M4RA 1NCFA 3U3PA 3ME4A 4J6GC
chains in the Genus database with same CATH superfamily
3MI8D 2HEYR 3QD6R 3QBQB 1DU3A 5IHLA 3MHDD 4KGGC 5CIRE 4YN0A 1SG1X 2E4UA 3U3QA 3K51B 3QO4A 3MBWA 1TNRR 2QR6A 3THMF 1JMAB 1D4VA 4KGQC 2E4WA 4BK5A 5DMJA 4FHQA 3BUKC 3TJEF 4OD2S 5L36B 4I9XC 2AW2B 1D0GR 2E4YA 4N90R 3FL7A 3U3SA 4E4DR 3WVTA 3X3FA 4RSUD 2HEVR 3ALQR 4GIQR 1FT4A 2UWIA 1ZA3R 3URFZ 3IJ2X 4MSVB 4BK4A 4MXWR 2E4XA 3ME2R 3U3TA 2E4VA 5BNQR 1EXTA 2X10A 4M4PA 3U3VA 2H9GR 4M4RA 1NCFA 3U3PA 3ME4A 4J6GC
chains in the Genus database with same CATH topology
3MI8D 2HEYR 3QD6R 3QBQB 1DU3A 5IHLA 3MHDD 4KGGC 5CIRE 4YN0A 1SG1X 3U3QA 3K51B 3QO4A 3MBWA 1TNRR 3THMF 1JMAB 1D4VA 4KGQC 4BK5A 5DMJA 4FHQA 3BUKC 3TJEF 4OD2S 5L36B 4I9XC 2AW2B 1D0GR 4N90R 3U3SA 3FL7A 4E4DR 3WVTA 3X3FA 4RSUD 2HEVR 3ALQR 4GIQR 1FT4A 2UWIA 1ZA3R 3URFZ 3IJ2X 4MSVB 4BK4A 4MXWR 3ME2R 3U3TA 5BNQR 1EXTA 2X10A 4M4PA 3U3VA 2H9GR 4M4RA 1NCFA 3U3PA 3ME4A 4J6GC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MI8 D;  2HEY R;  3QD6 R;  3QBQ B;  1DU3 A;  5IHL A;  3MHD D;  4KGG C;  5CIR E;  4YN0 A;  1SG1 X;  3U3Q A;  3K51 B;  3QO4 A;  3MBW A;  1TNR R;  3THM F;  1JMA B;  1D4V A;  4KGQ C;  4BK5 A;  5DMJ A;  4FHQ A;  3BUK C;  3TJE F;  4OD2 S;  5L36 B;  4I9X C;  2AW2 B;  1D0G R;  4N90 R;  3U3S A;  3FL7 A;  4E4D R;  3WVT A;  3X3F A;  4RSU D;  2HEV R;  3ALQ R;  4GIQ R;  1FT4 A;  2UWI A;  1ZA3 R;  3URF Z;  3IJ2 X;  4MSV B;  4BK4 A;  4MXW R;  3ME2 R;  3U3T A;  5BNQ R;  1EXT A;  2X10 A;  4M4P A;  3U3V A;  2H9G R;  4M4R A;  1NCF A;  3U3P A;  3ME4 A;  4J6G C; 
#chains in the Genus database with same CATH topology
 3MI8 D;  2HEY R;  3QD6 R;  3QBQ B;  1DU3 A;  5IHL A;  3MHD D;  4KGG C;  5CIR E;  4YN0 A;  1SG1 X;  2E4U A;  3U3Q A;  3K51 B;  3QO4 A;  3MBW A;  1TNR R;  2QR6 A;  3THM F;  1JMA B;  1D4V A;  4KGQ C;  2E4W A;  4BK5 A;  5DMJ A;  4FHQ A;  3BUK C;  3TJE F;  4OD2 S;  5L36 B;  4I9X C;  2AW2 B;  1D0G R;  2E4Y A;  4N90 R;  3FL7 A;  3U3S A;  4E4D R;  3WVT A;  3X3F A;  4RSU D;  2HEV R;  3ALQ R;  4GIQ R;  1FT4 A;  2UWI A;  1ZA3 R;  3URF Z;  3IJ2 X;  4MSV B;  4BK4 A;  4MXW R;  2E4X A;  3ME2 R;  3U3T A;  2E4V A;  5BNQ R;  1EXT A;  2X10 A;  4M4P A;  3U3V A;  2H9G R;  4M4R A;  1NCF A;  3U3P A;  3ME4 A;  4J6G C; 
#chains in the Genus database with same CATH homology
 3MI8 D;  2HEY R;  3QD6 R;  3QBQ B;  1DU3 A;  5IHL A;  3MHD D;  4KGG C;  5CIR E;  4YN0 A;  1SG1 X;  3U3Q A;  3K51 B;  3QO4 A;  3MBW A;  1TNR R;  3THM F;  1JMA B;  1D4V A;  4KGQ C;  4BK5 A;  5DMJ A;  4FHQ A;  3BUK C;  3TJE F;  4OD2 S;  5L36 B;  4I9X C;  2AW2 B;  1D0G R;  4N90 R;  3U3S A;  3FL7 A;  4E4D R;  3WVT A;  3X3F A;  4RSU D;  2HEV R;  3ALQ R;  4GIQ R;  1FT4 A;  2UWI A;  1ZA3 R;  3URF Z;  3IJ2 X;  4MSV B;  4BK4 A;  4MXW R;  3ME2 R;  3U3T A;  5BNQ R;  1EXT A;  2X10 A;  4M4P A;  3U3V A;  2H9G R;  4M4R A;  1NCF A;  3U3P A;  3ME4 A;  4J6G C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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