3ISMA

Crystal structure of the endog/endogi complex: mechanism of endog inhibition
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
245
structure length
245
Chain Sequence
TATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQINRKQLTTINGKKVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
pubmed doi rcsb
molecule keywords CG8862
molecule tags Hydrolase inhibitor/hydrolase
source organism Drosophila melanogaster
total genus 71
structure length 245
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3ismA00
5L0BA 3NKNA 3WAVA 4GTZA 4ZGAA 4B56A 5DLVA 4QGOA 5HRTA 5LIAA 5L0EA 5GKPA 1SMNA 4QN0A 3S5BA 3WAYA 1QAEA 4GTWA 4GTYA 2XRGA 2XH3A 4A1NA 1G8TA 4GTXA 3WAXA 5KXAA 3OWVA 5DLTA 2XGRA 5GKCA 5IJSA 4E3YA 5DLWA 5L0KA 4QH0A 3NKOA 3NKPA 3ISMA 3NKMA 4ZG7A 4ZG6A 1QL0A 5LQQA 5IJQA 2O3BA 3WAWA 2XR9A 5INHA 3NKQA 1ZM8A 3NKRA 4ZG9A
chains in the Genus database with same CATH superfamily
5L0BA 3NKNA 3WAVA 4GTZA 4ZGAA 4B56A 5DLVA 4QGOA 5HRTA 5LIAA 5L0EA 5GKPA 1SMNA 4QN0A 3S5BA 3WAYA 1QAEA 4GTWA 4GTYA 2XRGA 2XH3A 4A1NA 1G8TA 4GTXA 3WAXA 5KXAA 3OWVA 5DLTA 2XGRA 5GKCA 5IJSA 4E3YA 5DLWA 5L0KA 4QH0A 3NKOA 3NKPA 3ISMA 3NKMA 4ZG7A 4ZG6A 1QL0A 5LQQA 5IJQA 2O3BA 3WAWA 2XR9A 5INHA 3NKQA 1ZM8A 3NKRA 4ZG9A
chains in the Genus database with same CATH topology
5L0BA 3NKNA 3WAVA 4GTZA 4ZGAA 4B56A 5DLVA 4QGOA 5HRTA 5LIAA 5L0EA 5GKPA 1SMNA 4QN0A 3S5BA 3WAYA 1QAEA 4GTWA 4GTYA 2XRGA 2XH3A 4A1NA 1G8TA 4GTXA 3WAXA 5KXAA 3OWVA 5DLTA 2XGRA 5GKCA 5IJSA 4E3YA 5DLWA 5L0KA 4QH0A 3NKOA 3NKPA 3ISMA 3NKMA 4ZG7A 4ZG6A 1QL0A 5LQQA 5IJQA 2O3BA 3WAWA 2XR9A 5INHA 3NKQA 1ZM8A 3NKRA 4ZG9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L0B A;  3NKN A;  3WAV A;  4GTZ A;  4ZGA A;  4B56 A;  5DLV A;  4QGO A;  5HRT A;  5LIA A;  5L0E A;  5GKP A;  1SMN A;  4QN0 A;  3S5B A;  3WAY A;  1QAE A;  4GTW A;  4GTY A;  2XRG A;  2XH3 A;  4A1N A;  1G8T A;  4GTX A;  3WAX A;  5KXA A;  3OWV A;  5DLT A;  2XGR A;  5GKC A;  5IJS A;  4E3Y A;  5DLW A;  5L0K A;  4QH0 A;  3NKO A;  3NKP A;  3ISM A;  3NKM A;  4ZG7 A;  4ZG6 A;  1QL0 A;  5LQQ A;  5IJQ A;  2O3B A;  3WAW A;  2XR9 A;  5INH A;  3NKQ A;  1ZM8 A;  3NKR A;  4ZG9 A; 
#chains in the Genus database with same CATH topology
 5L0B A;  3NKN A;  3WAV A;  4GTZ A;  4ZGA A;  4B56 A;  5DLV A;  4QGO A;  5HRT A;  5LIA A;  5L0E A;  5GKP A;  1SMN A;  4QN0 A;  3S5B A;  3WAY A;  1QAE A;  4GTW A;  4GTY A;  2XRG A;  2XH3 A;  4A1N A;  1G8T A;  4GTX A;  3WAX A;  5KXA A;  3OWV A;  5DLT A;  2XGR A;  5GKC A;  5IJS A;  4E3Y A;  5DLW A;  5L0K A;  4QH0 A;  3NKO A;  3NKP A;  3ISM A;  3NKM A;  4ZG7 A;  4ZG6 A;  1QL0 A;  5LQQ A;  5IJQ A;  2O3B A;  3WAW A;  2XR9 A;  5INH A;  3NKQ A;  1ZM8 A;  3NKR A;  4ZG9 A; 
#chains in the Genus database with same CATH homology
 5L0B A;  3NKN A;  3WAV A;  4GTZ A;  4ZGA A;  4B56 A;  5DLV A;  4QGO A;  5HRT A;  5LIA A;  5L0E A;  5GKP A;  1SMN A;  4QN0 A;  3S5B A;  3WAY A;  1QAE A;  4GTW A;  4GTY A;  2XRG A;  2XH3 A;  4A1N A;  1G8T A;  4GTX A;  3WAX A;  5KXA A;  3OWV A;  5DLT A;  2XGR A;  5GKC A;  5IJS A;  4E3Y A;  5DLW A;  5L0K A;  4QH0 A;  3NKO A;  3NKP A;  3ISM A;  3NKM A;  4ZG7 A;  4ZG6 A;  1QL0 A;  5LQQ A;  5IJQ A;  2O3B A;  3WAW A;  2XR9 A;  5INH A;  3NKQ A;  1ZM8 A;  3NKR A;  4ZG9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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