3ISMA

Crystal structure of the endog/endogi complex: mechanism of endog inhibition
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
245
structure length
245
Chain Sequence
TATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQINRKQLTTINGKKVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
pubmed doi rcsb
molecule keywords CG8862
molecule tags Hydrolase inhibitor/hydrolase
source organism Drosophila melanogaster
total genus 71
structure length 245
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3ismA00
5HRTA 3NKQA 4ZG9A 1ZM8A 5DLWA 5IJSA 3NKPA 2XR9A 1QAEA 4ZG7A 5DLVA 3WAYA 4E3YA 3WAWA 3NKNA 4ZGAA 5IJQA 4A1NA 5LIAA 5L0BA 3WAVA 4GTXA 5GKCA 2O3BA 3NKMA 1G8TA 4GTWA 5INHA 5L0EA 4GTZA 5KXAA 5GKPA 5LQQA 4B56A 3NKOA 4ZG6A 3OWVA 4GTYA 2XRGA 1SMNA 3ISMA 4QH0A 3NKRA 4QN0A 5DLTA 3WAXA 3S5BA 5L0KA 4QGOA 2XH3A 2XGRA 1QL0A
chains in the Genus database with same CATH superfamily
5HRTA 3NKQA 4ZG9A 1ZM8A 5DLWA 5IJSA 3NKPA 2XR9A 1QAEA 4ZG7A 5DLVA 3WAYA 4E3YA 3WAWA 3NKNA 4ZGAA 5IJQA 4A1NA 5LIAA 5L0BA 3WAVA 4GTXA 5GKCA 2O3BA 3NKMA 1G8TA 4GTWA 5INHA 5L0EA 4GTZA 5KXAA 5GKPA 5LQQA 4B56A 3NKOA 4ZG6A 3OWVA 4GTYA 2XRGA 1SMNA 3ISMA 4QH0A 3NKRA 4QN0A 5DLTA 3WAXA 3S5BA 5L0KA 4QGOA 2XH3A 2XGRA 1QL0A
chains in the Genus database with same CATH topology
5HRTA 3NKQA 4ZG9A 1ZM8A 5DLWA 5IJSA 3NKPA 2XR9A 1QAEA 4ZG7A 5DLVA 3WAYA 4E3YA 3WAWA 3NKNA 4ZGAA 5IJQA 4A1NA 5LIAA 5L0BA 3WAVA 4GTXA 5GKCA 2O3BA 3NKMA 1G8TA 4GTWA 5INHA 5L0EA 4GTZA 5KXAA 5GKPA 5LQQA 4B56A 3NKOA 4ZG6A 3OWVA 4GTYA 2XRGA 1SMNA 3ISMA 4QH0A 3NKRA 4QN0A 5DLTA 3WAXA 3S5BA 5L0KA 4QGOA 2XH3A 2XGRA 1QL0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HRT A;  3NKQ A;  4ZG9 A;  1ZM8 A;  5DLW A;  5IJS A;  3NKP A;  2XR9 A;  1QAE A;  4ZG7 A;  5DLV A;  3WAY A;  4E3Y A;  3WAW A;  3NKN A;  4ZGA A;  5IJQ A;  4A1N A;  5LIA A;  5L0B A;  3WAV A;  4GTX A;  5GKC A;  2O3B A;  3NKM A;  1G8T A;  4GTW A;  5INH A;  5L0E A;  4GTZ A;  5KXA A;  5GKP A;  5LQQ A;  4B56 A;  3NKO A;  4ZG6 A;  3OWV A;  4GTY A;  2XRG A;  1SMN A;  3ISM A;  4QH0 A;  3NKR A;  4QN0 A;  5DLT A;  3WAX A;  3S5B A;  5L0K A;  4QGO A;  2XH3 A;  2XGR A;  1QL0 A; 
#chains in the Genus database with same CATH topology
 5HRT A;  3NKQ A;  4ZG9 A;  1ZM8 A;  5DLW A;  5IJS A;  3NKP A;  2XR9 A;  1QAE A;  4ZG7 A;  5DLV A;  3WAY A;  4E3Y A;  3WAW A;  3NKN A;  4ZGA A;  5IJQ A;  4A1N A;  5LIA A;  5L0B A;  3WAV A;  4GTX A;  5GKC A;  2O3B A;  3NKM A;  1G8T A;  4GTW A;  5INH A;  5L0E A;  4GTZ A;  5KXA A;  5GKP A;  5LQQ A;  4B56 A;  3NKO A;  4ZG6 A;  3OWV A;  4GTY A;  2XRG A;  1SMN A;  3ISM A;  4QH0 A;  3NKR A;  4QN0 A;  5DLT A;  3WAX A;  3S5B A;  5L0K A;  4QGO A;  2XH3 A;  2XGR A;  1QL0 A; 
#chains in the Genus database with same CATH homology
 5HRT A;  3NKQ A;  4ZG9 A;  1ZM8 A;  5DLW A;  5IJS A;  3NKP A;  2XR9 A;  1QAE A;  4ZG7 A;  5DLV A;  3WAY A;  4E3Y A;  3WAW A;  3NKN A;  4ZGA A;  5IJQ A;  4A1N A;  5LIA A;  5L0B A;  3WAV A;  4GTX A;  5GKC A;  2O3B A;  3NKM A;  1G8T A;  4GTW A;  5INH A;  5L0E A;  4GTZ A;  5KXA A;  5GKP A;  5LQQ A;  4B56 A;  3NKO A;  4ZG6 A;  3OWV A;  4GTY A;  2XRG A;  1SMN A;  3ISM A;  4QH0 A;  3NKR A;  4QN0 A;  5DLT A;  3WAX A;  3S5B A;  5L0K A;  4QGO A;  2XH3 A;  2XGR A;  1QL0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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