3ISMA

Crystal structure of the endog/endogi complex: mechanism of endog inhibition
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
245
structure length
245
Chain Sequence
TATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQINRKQLTTINGKKVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
pubmed doi rcsb
molecule tags Hydrolase inhibitor/hydrolase
source organism Drosophila melanogaster
molecule keywords CG8862
total genus 71
structure length 245
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3ismA00
5LQQA 4ZG6A 4B56A 5L0KA 5IJSA 5IJQA 3NKOA 2XRGA 4ZG7A 4GTWA 3S5BA 3NKPA 1SMNA 2XH3A 3NKNA 4QN0A 1QAEA 5DLWA 4A1NA 3NKMA 4QGOA 5GKPA 4GTYA 5DLTA 3WAYA 4ZG9A 3OWVA 3WAWA 1ZM8A 3NKRA 3WAXA 1QL0A 2XGRA 3ISMA 5HRTA 2XR9A 4GTXA 5INHA 4QH0A 4ZGAA 2O3BA 5LIAA 3NKQA 5L0EA 5L0BA 5GKCA 1G8TA 4E3YA 5KXAA 4GTZA 5DLVA 3WAVA
chains in the Genus database with same CATH superfamily
5LQQA 4ZG6A 4B56A 5L0KA 5IJSA 5IJQA 3NKOA 2XRGA 4ZG7A 4GTWA 3S5BA 3NKPA 1SMNA 2XH3A 3NKNA 4QN0A 1QAEA 5DLWA 4A1NA 3NKMA 4QGOA 5GKPA 4GTYA 5DLTA 3WAYA 4ZG9A 3OWVA 3WAWA 1ZM8A 3NKRA 3WAXA 1QL0A 2XGRA 3ISMA 5HRTA 2XR9A 4GTXA 5INHA 4QH0A 4ZGAA 2O3BA 5LIAA 3NKQA 5L0EA 5L0BA 5GKCA 1G8TA 4E3YA 5KXAA 4GTZA 5DLVA 3WAVA
chains in the Genus database with same CATH topology
5LQQA 4ZG6A 4B56A 5L0KA 5IJSA 5IJQA 3NKOA 2XRGA 4ZG7A 4GTWA 3S5BA 3NKPA 1SMNA 2XH3A 3NKNA 4QN0A 1QAEA 5DLWA 4A1NA 3NKMA 4QGOA 5GKPA 4GTYA 5DLTA 3WAYA 4ZG9A 3OWVA 3WAWA 1ZM8A 3NKRA 3WAXA 1QL0A 2XGRA 3ISMA 5HRTA 2XR9A 4GTXA 5INHA 4QH0A 4ZGAA 2O3BA 5LIAA 3NKQA 5L0EA 5L0BA 5GKCA 1G8TA 4E3YA 5KXAA 4GTZA 5DLVA 3WAVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LQQ A;  4ZG6 A;  4B56 A;  5L0K A;  5IJS A;  5IJQ A;  3NKO A;  2XRG A;  4ZG7 A;  4GTW A;  3S5B A;  3NKP A;  1SMN A;  2XH3 A;  3NKN A;  4QN0 A;  1QAE A;  5DLW A;  4A1N A;  3NKM A;  4QGO A;  5GKP A;  4GTY A;  5DLT A;  3WAY A;  4ZG9 A;  3OWV A;  3WAW A;  1ZM8 A;  3NKR A;  3WAX A;  1QL0 A;  2XGR A;  3ISM A;  5HRT A;  2XR9 A;  4GTX A;  5INH A;  4QH0 A;  4ZGA A;  2O3B A;  5LIA A;  3NKQ A;  5L0E A;  5L0B A;  5GKC A;  1G8T A;  4E3Y A;  5KXA A;  4GTZ A;  5DLV A;  3WAV A; 
#chains in the Genus database with same CATH topology
 5LQQ A;  4ZG6 A;  4B56 A;  5L0K A;  5IJS A;  5IJQ A;  3NKO A;  2XRG A;  4ZG7 A;  4GTW A;  3S5B A;  3NKP A;  1SMN A;  2XH3 A;  3NKN A;  4QN0 A;  1QAE A;  5DLW A;  4A1N A;  3NKM A;  4QGO A;  5GKP A;  4GTY A;  5DLT A;  3WAY A;  4ZG9 A;  3OWV A;  3WAW A;  1ZM8 A;  3NKR A;  3WAX A;  1QL0 A;  2XGR A;  3ISM A;  5HRT A;  2XR9 A;  4GTX A;  5INH A;  4QH0 A;  4ZGA A;  2O3B A;  5LIA A;  3NKQ A;  5L0E A;  5L0B A;  5GKC A;  1G8T A;  4E3Y A;  5KXA A;  4GTZ A;  5DLV A;  3WAV A; 
#chains in the Genus database with same CATH homology
 5LQQ A;  4ZG6 A;  4B56 A;  5L0K A;  5IJS A;  5IJQ A;  3NKO A;  2XRG A;  4ZG7 A;  4GTW A;  3S5B A;  3NKP A;  1SMN A;  2XH3 A;  3NKN A;  4QN0 A;  1QAE A;  5DLW A;  4A1N A;  3NKM A;  4QGO A;  5GKP A;  4GTY A;  5DLT A;  3WAY A;  4ZG9 A;  3OWV A;  3WAW A;  1ZM8 A;  3NKR A;  3WAX A;  1QL0 A;  2XGR A;  3ISM A;  5HRT A;  2XR9 A;  4GTX A;  5INH A;  4QH0 A;  4ZGA A;  2O3B A;  5LIA A;  3NKQ A;  5L0E A;  5L0B A;  5GKC A;  1G8T A;  4E3Y A;  5KXA A;  4GTZ A;  5DLV A;  3WAV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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