3ISMA

Crystal structure of the endog/endogi complex: mechanism of endog inhibition
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
245
structure length
245
Chain Sequence
TATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQINRKQLTTINGKKVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
pubmed doi rcsb
molecule tags Hydrolase inhibitor/hydrolase
source organism Drosophila melanogaster
molecule keywords CG8862
total genus 71
structure length 245
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3ismA00
4GTXA 4QH0A 4B56A 5DLWA 4ZGAA 5LQQA 3NKNA 2XRGA 3NKMA 5L0BA 3WAXA 3WAYA 5KXAA 1ZM8A 2O3BA 3NKOA 4QGOA 5DLVA 4ZG7A 2XR9A 3WAWA 5LIAA 5GKPA 5DLTA 3ISMA 1QL0A 3WAVA 5IJQA 2XH3A 3S5BA 4ZG9A 5GKCA 4GTZA 1QAEA 5L0KA 4A1NA 4E3YA 5INHA 3NKRA 3OWVA 4GTWA 3NKPA 4GTYA 4ZG6A 2XGRA 5HRTA 4QN0A 3NKQA 5IJSA 1G8TA 5L0EA 1SMNA
chains in the Genus database with same CATH superfamily
4GTXA 4QH0A 4B56A 5DLWA 4ZGAA 5LQQA 3NKNA 2XRGA 3NKMA 5L0BA 3WAXA 3WAYA 5KXAA 1ZM8A 2O3BA 3NKOA 4QGOA 5DLVA 4ZG7A 2XR9A 3WAWA 5LIAA 5GKPA 5DLTA 3ISMA 1QL0A 3WAVA 5IJQA 2XH3A 3S5BA 4ZG9A 5GKCA 4GTZA 1QAEA 5L0KA 4A1NA 4E3YA 5INHA 3NKRA 3OWVA 4GTWA 3NKPA 4GTYA 4ZG6A 2XGRA 5HRTA 4QN0A 3NKQA 5IJSA 1G8TA 5L0EA 1SMNA
chains in the Genus database with same CATH topology
4GTXA 4QH0A 4B56A 5DLWA 4ZGAA 5LQQA 3NKNA 2XRGA 3NKMA 5L0BA 3WAXA 3WAYA 5KXAA 1ZM8A 2O3BA 3NKOA 4QGOA 5DLVA 4ZG7A 2XR9A 3WAWA 5LIAA 5GKPA 5DLTA 3ISMA 1QL0A 3WAVA 5IJQA 2XH3A 3S5BA 4ZG9A 5GKCA 4GTZA 1QAEA 5L0KA 4A1NA 4E3YA 5INHA 3NKRA 3OWVA 4GTWA 3NKPA 4GTYA 4ZG6A 2XGRA 5HRTA 4QN0A 3NKQA 5IJSA 1G8TA 5L0EA 1SMNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GTX A;  4QH0 A;  4B56 A;  5DLW A;  4ZGA A;  5LQQ A;  3NKN A;  2XRG A;  3NKM A;  5L0B A;  3WAX A;  3WAY A;  5KXA A;  1ZM8 A;  2O3B A;  3NKO A;  4QGO A;  5DLV A;  4ZG7 A;  2XR9 A;  3WAW A;  5LIA A;  5GKP A;  5DLT A;  3ISM A;  1QL0 A;  3WAV A;  5IJQ A;  2XH3 A;  3S5B A;  4ZG9 A;  5GKC A;  4GTZ A;  1QAE A;  5L0K A;  4A1N A;  4E3Y A;  5INH A;  3NKR A;  3OWV A;  4GTW A;  3NKP A;  4GTY A;  4ZG6 A;  2XGR A;  5HRT A;  4QN0 A;  3NKQ A;  5IJS A;  1G8T A;  5L0E A;  1SMN A; 
#chains in the Genus database with same CATH topology
 4GTX A;  4QH0 A;  4B56 A;  5DLW A;  4ZGA A;  5LQQ A;  3NKN A;  2XRG A;  3NKM A;  5L0B A;  3WAX A;  3WAY A;  5KXA A;  1ZM8 A;  2O3B A;  3NKO A;  4QGO A;  5DLV A;  4ZG7 A;  2XR9 A;  3WAW A;  5LIA A;  5GKP A;  5DLT A;  3ISM A;  1QL0 A;  3WAV A;  5IJQ A;  2XH3 A;  3S5B A;  4ZG9 A;  5GKC A;  4GTZ A;  1QAE A;  5L0K A;  4A1N A;  4E3Y A;  5INH A;  3NKR A;  3OWV A;  4GTW A;  3NKP A;  4GTY A;  4ZG6 A;  2XGR A;  5HRT A;  4QN0 A;  3NKQ A;  5IJS A;  1G8T A;  5L0E A;  1SMN A; 
#chains in the Genus database with same CATH homology
 4GTX A;  4QH0 A;  4B56 A;  5DLW A;  4ZGA A;  5LQQ A;  3NKN A;  2XRG A;  3NKM A;  5L0B A;  3WAX A;  3WAY A;  5KXA A;  1ZM8 A;  2O3B A;  3NKO A;  4QGO A;  5DLV A;  4ZG7 A;  2XR9 A;  3WAW A;  5LIA A;  5GKP A;  5DLT A;  3ISM A;  1QL0 A;  3WAV A;  5IJQ A;  2XH3 A;  3S5B A;  4ZG9 A;  5GKC A;  4GTZ A;  1QAE A;  5L0K A;  4A1N A;  4E3Y A;  5INH A;  3NKR A;  3OWV A;  4GTW A;  3NKP A;  4GTY A;  4ZG6 A;  2XGR A;  5HRT A;  4QN0 A;  3NKQ A;  5IJS A;  1G8T A;  5L0E A;  1SMN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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