3OWVA

Structural insights into catalytic and substrate binding mechanisms of the strategic enda nuclease from streptococcus pneumoniae
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
229
structure length
218
Chain Sequence
SEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYSWTPPGWHQVKNLKGSYTHAVDRGALLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
pubmed doi rcsb
molecule keywords DNA-entry nuclease
molecule tags Hydrolase
source organism Streptococcus pneumoniae
total genus 59
structure length 218
sequence length 229
chains with identical sequence B
ec nomenclature ec 3.1.30.-:
pdb deposition date 2010-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3owvA00
1QAEA 4ZG7A 3WAXA 2XH3A 1G8TA 1SMNA 4GTZA 4B56A 4A1NA 5DLVA 5GKPA 5GKCA 5INHA 4QN0A 5DLWA 3WAVA 5LQQA 4QGOA 4GTXA 4QH0A 4GTYA 2O3BA 4ZG6A 4ZGAA 4E3YA 3WAWA 5HRTA 3S5BA 3ISMA 5L0BA 3NKPA 5IJSA 5L0KA 3NKNA 5KXAA 5LIAA 3NKOA 3NKMA 2XGRA 4GTWA 1QL0A 5IJQA 3NKQA 3WAYA 4ZG9A 5L0EA 2XR9A 5DLTA 3NKRA 1ZM8A 3OWVA 2XRGA
chains in the Genus database with same CATH superfamily
1QAEA 4ZG7A 3WAXA 2XH3A 1G8TA 1SMNA 4GTZA 4B56A 4A1NA 5DLVA 5GKPA 5GKCA 5INHA 4QN0A 5DLWA 3WAVA 5LQQA 4QGOA 4GTXA 4QH0A 4GTYA 2O3BA 4ZG6A 4ZGAA 4E3YA 3WAWA 5HRTA 3S5BA 3ISMA 5L0BA 3NKPA 5IJSA 5L0KA 3NKNA 5KXAA 5LIAA 3NKOA 3NKMA 2XGRA 4GTWA 1QL0A 5IJQA 3NKQA 3WAYA 4ZG9A 5L0EA 2XR9A 5DLTA 3NKRA 1ZM8A 3OWVA 2XRGA
chains in the Genus database with same CATH topology
1QAEA 4ZG7A 3WAXA 2XH3A 1G8TA 1SMNA 4GTZA 4B56A 4A1NA 5DLVA 5GKPA 5GKCA 5INHA 4QN0A 5DLWA 3WAVA 5LQQA 4QGOA 4GTXA 4QH0A 4GTYA 2O3BA 4ZG6A 4ZGAA 4E3YA 3WAWA 5HRTA 3S5BA 3ISMA 5L0BA 3NKPA 5IJSA 5L0KA 3NKNA 5KXAA 5LIAA 3NKOA 3NKMA 2XGRA 4GTWA 1QL0A 5IJQA 3NKQA 3WAYA 4ZG9A 5L0EA 2XR9A 5DLTA 3NKRA 1ZM8A 3OWVA 2XRGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QAE A;  4ZG7 A;  3WAX A;  2XH3 A;  1G8T A;  1SMN A;  4GTZ A;  4B56 A;  4A1N A;  5DLV A;  5GKP A;  5GKC A;  5INH A;  4QN0 A;  5DLW A;  3WAV A;  5LQQ A;  4QGO A;  4GTX A;  4QH0 A;  4GTY A;  2O3B A;  4ZG6 A;  4ZGA A;  4E3Y A;  3WAW A;  5HRT A;  3S5B A;  3ISM A;  5L0B A;  3NKP A;  5IJS A;  5L0K A;  3NKN A;  5KXA A;  5LIA A;  3NKO A;  3NKM A;  2XGR A;  4GTW A;  1QL0 A;  5IJQ A;  3NKQ A;  3WAY A;  4ZG9 A;  5L0E A;  2XR9 A;  5DLT A;  3NKR A;  1ZM8 A;  3OWV A;  2XRG A; 
#chains in the Genus database with same CATH topology
 1QAE A;  4ZG7 A;  3WAX A;  2XH3 A;  1G8T A;  1SMN A;  4GTZ A;  4B56 A;  4A1N A;  5DLV A;  5GKP A;  5GKC A;  5INH A;  4QN0 A;  5DLW A;  3WAV A;  5LQQ A;  4QGO A;  4GTX A;  4QH0 A;  4GTY A;  2O3B A;  4ZG6 A;  4ZGA A;  4E3Y A;  3WAW A;  5HRT A;  3S5B A;  3ISM A;  5L0B A;  3NKP A;  5IJS A;  5L0K A;  3NKN A;  5KXA A;  5LIA A;  3NKO A;  3NKM A;  2XGR A;  4GTW A;  1QL0 A;  5IJQ A;  3NKQ A;  3WAY A;  4ZG9 A;  5L0E A;  2XR9 A;  5DLT A;  3NKR A;  1ZM8 A;  3OWV A;  2XRG A; 
#chains in the Genus database with same CATH homology
 1QAE A;  4ZG7 A;  3WAX A;  2XH3 A;  1G8T A;  1SMN A;  4GTZ A;  4B56 A;  4A1N A;  5DLV A;  5GKP A;  5GKC A;  5INH A;  4QN0 A;  5DLW A;  3WAV A;  5LQQ A;  4QGO A;  4GTX A;  4QH0 A;  4GTY A;  2O3B A;  4ZG6 A;  4ZGA A;  4E3Y A;  3WAW A;  5HRT A;  3S5B A;  3ISM A;  5L0B A;  3NKP A;  5IJS A;  5L0K A;  3NKN A;  5KXA A;  5LIA A;  3NKO A;  3NKM A;  2XGR A;  4GTW A;  1QL0 A;  5IJQ A;  3NKQ A;  3WAY A;  4ZG9 A;  5L0E A;  2XR9 A;  5DLT A;  3NKR A;  1ZM8 A;  3OWV A;  2XRG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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