3OWVA

Structural insights into catalytic and substrate binding mechanisms of the strategic enda nuclease from streptococcus pneumoniae
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
229
structure length
218
Chain Sequence
SEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYSWTPPGWHQVKNLKGSYTHAVDRGALLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
pubmed doi rcsb
molecule tags Hydrolase
source organism Streptococcus pneumoniae
molecule keywords DNA-entry nuclease
total genus 59
structure length 218
sequence length 229
chains with identical sequence B
ec nomenclature ec 3.1.30.-:
pdb deposition date 2010-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3owvA00
3NKRA 3WAXA 5L0BA 2XRGA 3WAWA 5DLTA 4GTWA 5DLVA 1SMNA 3S5BA 3NKPA 3ISMA 4ZG7A 3NKOA 4B56A 3WAYA 5INHA 3WAVA 5IJSA 4QN0A 3NKNA 4GTZA 4ZG6A 5GKPA 5HRTA 5KXAA 4QGOA 3NKQA 1QL0A 4A1NA 4GTYA 4E3YA 4GTXA 2O3BA 5LQQA 1ZM8A 5IJQA 5LIAA 5L0KA 3OWVA 4QH0A 4ZG9A 5GKCA 2XGRA 3NKMA 2XR9A 1G8TA 1QAEA 2XH3A 4ZGAA 5L0EA 5DLWA
chains in the Genus database with same CATH superfamily
3NKRA 3WAXA 5L0BA 2XRGA 3WAWA 5DLTA 4GTWA 5DLVA 1SMNA 3S5BA 3NKPA 3ISMA 4ZG7A 3NKOA 4B56A 3WAYA 5INHA 3WAVA 5IJSA 4QN0A 3NKNA 4GTZA 4ZG6A 5GKPA 5HRTA 5KXAA 4QGOA 3NKQA 1QL0A 4A1NA 4GTYA 4E3YA 4GTXA 2O3BA 5LQQA 1ZM8A 5IJQA 5LIAA 5L0KA 3OWVA 4QH0A 4ZG9A 5GKCA 2XGRA 3NKMA 2XR9A 1G8TA 1QAEA 2XH3A 4ZGAA 5L0EA 5DLWA
chains in the Genus database with same CATH topology
3NKRA 3WAXA 5L0BA 2XRGA 3WAWA 5DLTA 4GTWA 5DLVA 1SMNA 3S5BA 3NKPA 3ISMA 4ZG7A 3NKOA 4B56A 3WAYA 5INHA 3WAVA 5IJSA 4QN0A 3NKNA 4GTZA 4ZG6A 5GKPA 5HRTA 5KXAA 4QGOA 3NKQA 1QL0A 4A1NA 4GTYA 4E3YA 4GTXA 2O3BA 5LQQA 1ZM8A 5IJQA 5LIAA 5L0KA 3OWVA 4QH0A 4ZG9A 5GKCA 2XGRA 3NKMA 2XR9A 1G8TA 1QAEA 2XH3A 4ZGAA 5L0EA 5DLWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NKR A;  3WAX A;  5L0B A;  2XRG A;  3WAW A;  5DLT A;  4GTW A;  5DLV A;  1SMN A;  3S5B A;  3NKP A;  3ISM A;  4ZG7 A;  3NKO A;  4B56 A;  3WAY A;  5INH A;  3WAV A;  5IJS A;  4QN0 A;  3NKN A;  4GTZ A;  4ZG6 A;  5GKP A;  5HRT A;  5KXA A;  4QGO A;  3NKQ A;  1QL0 A;  4A1N A;  4GTY A;  4E3Y A;  4GTX A;  2O3B A;  5LQQ A;  1ZM8 A;  5IJQ A;  5LIA A;  5L0K A;  3OWV A;  4QH0 A;  4ZG9 A;  5GKC A;  2XGR A;  3NKM A;  2XR9 A;  1G8T A;  1QAE A;  2XH3 A;  4ZGA A;  5L0E A;  5DLW A; 
#chains in the Genus database with same CATH topology
 3NKR A;  3WAX A;  5L0B A;  2XRG A;  3WAW A;  5DLT A;  4GTW A;  5DLV A;  1SMN A;  3S5B A;  3NKP A;  3ISM A;  4ZG7 A;  3NKO A;  4B56 A;  3WAY A;  5INH A;  3WAV A;  5IJS A;  4QN0 A;  3NKN A;  4GTZ A;  4ZG6 A;  5GKP A;  5HRT A;  5KXA A;  4QGO A;  3NKQ A;  1QL0 A;  4A1N A;  4GTY A;  4E3Y A;  4GTX A;  2O3B A;  5LQQ A;  1ZM8 A;  5IJQ A;  5LIA A;  5L0K A;  3OWV A;  4QH0 A;  4ZG9 A;  5GKC A;  2XGR A;  3NKM A;  2XR9 A;  1G8T A;  1QAE A;  2XH3 A;  4ZGA A;  5L0E A;  5DLW A; 
#chains in the Genus database with same CATH homology
 3NKR A;  3WAX A;  5L0B A;  2XRG A;  3WAW A;  5DLT A;  4GTW A;  5DLV A;  1SMN A;  3S5B A;  3NKP A;  3ISM A;  4ZG7 A;  3NKO A;  4B56 A;  3WAY A;  5INH A;  3WAV A;  5IJS A;  4QN0 A;  3NKN A;  4GTZ A;  4ZG6 A;  5GKP A;  5HRT A;  5KXA A;  4QGO A;  3NKQ A;  1QL0 A;  4A1N A;  4GTY A;  4E3Y A;  4GTX A;  2O3B A;  5LQQ A;  1ZM8 A;  5IJQ A;  5LIA A;  5L0K A;  3OWV A;  4QH0 A;  4ZG9 A;  5GKC A;  2XGR A;  3NKM A;  2XR9 A;  1G8T A;  1QAE A;  2XH3 A;  4ZGA A;  5L0E A;  5DLW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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