3QBQB

Crystal structure of extracellular domains of mouse rank-rankl complex
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
164
structure length
164
Chain Sequence
CTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWNSDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis
pubmed doi rcsb
molecule keywords Tumor necrosis factor ligand superfamily member 11
molecule tags Cytokine/cytokine receptor
source organism Mus musculus
total genus 29
structure length 164
sequence length 164
chains with identical sequence D
ec nomenclature
pdb deposition date 2011-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
B PF18278 RANK_CRD_2 Receptor activator of the NF-KB cysteine-rich repeat domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3qbqB02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3qbqB01
4KGGC 4FHQA 4MSVB 1JMAB 3MBWA 4YN0A 3U3TA 2X10A 3ME4A 3U3PA 4RSUD 3U3QA 4E4DR 3BUKC 4GIQR 3QBQB 3K51B 4M4RA 3X3FA 3MHDD 4OD2S 1D0GR 1DU3A 5CIRE 5IHLA 4BK4A 3MI8D 1EXTA 1ZA3R 4I9XC 4N90R 1D4VA 2UWIA 1FT4A 3U3VA 3WVTA 3TJEF 4M4PA 2AW2B 3THMF 3U3SA 2HEVR 5L36B 2HEYR 2H9GR 4KGQC 4BK5A 1NCFA 4MXWR 1SG1X 3ALQR 3IJ2X 4J6GC 1TNRR 5DMJA 3QD6R 3ME2R 3QO4A 3FL7A 5BNQR 3URFZ
chains in the Genus database with same CATH superfamily
4KGGC 2E4YA 4FHQA 4MSVB 1JMAB 3MBWA 4YN0A 3U3TA 2X10A 3ME4A 3U3PA 4RSUD 3U3QA 4E4DR 3BUKC 4GIQR 3QBQB 3K51B 4M4RA 3X3FA 3MHDD 4OD2S 2E4UA 1D0GR 1DU3A 5CIRE 5IHLA 4BK4A 3MI8D 1EXTA 1ZA3R 4I9XC 4N90R 1D4VA 1FT4A 2UWIA 3U3VA 3WVTA 3TJEF 4M4PA 2AW2B 3THMF 3U3SA 2HEVR 5L36B 2HEYR 2E4VA 2H9GR 4KGQC 4BK5A 1NCFA 4MXWR 2E4XA 1SG1X 2E4WA 2QR6A 3ALQR 3IJ2X 4J6GC 1TNRR 5DMJA 3QD6R 3ME2R 3QO4A 3FL7A 5BNQR 3URFZ
chains in the Genus database with same CATH topology
4KGGC 4FHQA 4MSVB 1JMAB 3MBWA 4YN0A 3U3TA 2X10A 3ME4A 3U3PA 4RSUD 3U3QA 4E4DR 3BUKC 4GIQR 3QBQB 3K51B 4M4RA 3X3FA 3MHDD 4OD2S 1D0GR 1DU3A 5CIRE 5IHLA 4BK4A 3MI8D 1EXTA 1ZA3R 4I9XC 4N90R 1D4VA 2UWIA 1FT4A 3U3VA 3WVTA 3TJEF 4M4PA 2AW2B 3THMF 3U3SA 2HEVR 5L36B 2HEYR 2H9GR 4KGQC 4BK5A 1NCFA 4MXWR 1SG1X 3ALQR 3IJ2X 4J6GC 1TNRR 5DMJA 3QD6R 3ME2R 3QO4A 3FL7A 5BNQR 3URFZ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KGG C;  4FHQ A;  4MSV B;  1JMA B;  3MBW A;  4YN0 A;  3U3T A;  2X10 A;  3ME4 A;  3U3P A;  4RSU D;  3U3Q A;  4E4D R;  3BUK C;  4GIQ R;  3QBQ B;  3K51 B;  4M4R A;  3X3F A;  3MHD D;  4OD2 S;  1D0G R;  1DU3 A;  5CIR E;  5IHL A;  4BK4 A;  3MI8 D;  1EXT A;  1ZA3 R;  4I9X C;  4N90 R;  1D4V A;  2UWI A;  1FT4 A;  3U3V A;  3WVT A;  3TJE F;  4M4P A;  2AW2 B;  3THM F;  3U3S A;  2HEV R;  5L36 B;  2HEY R;  2H9G R;  4KGQ C;  4BK5 A;  1NCF A;  4MXW R;  1SG1 X;  3ALQ R;  3IJ2 X;  4J6G C;  1TNR R;  5DMJ A;  3QD6 R;  3ME2 R;  3QO4 A;  3FL7 A;  5BNQ R;  3URF Z; 
#chains in the Genus database with same CATH topology
 4KGG C;  2E4Y A;  4FHQ A;  4MSV B;  1JMA B;  3MBW A;  4YN0 A;  3U3T A;  2X10 A;  3ME4 A;  3U3P A;  4RSU D;  3U3Q A;  4E4D R;  3BUK C;  4GIQ R;  3QBQ B;  3K51 B;  4M4R A;  3X3F A;  3MHD D;  4OD2 S;  2E4U A;  1D0G R;  1DU3 A;  5CIR E;  5IHL A;  4BK4 A;  3MI8 D;  1EXT A;  1ZA3 R;  4I9X C;  4N90 R;  1D4V A;  1FT4 A;  2UWI A;  3U3V A;  3WVT A;  3TJE F;  4M4P A;  2AW2 B;  3THM F;  3U3S A;  2HEV R;  5L36 B;  2HEY R;  2E4V A;  2H9G R;  4KGQ C;  4BK5 A;  1NCF A;  4MXW R;  2E4X A;  1SG1 X;  2E4W A;  2QR6 A;  3ALQ R;  3IJ2 X;  4J6G C;  1TNR R;  5DMJ A;  3QD6 R;  3ME2 R;  3QO4 A;  3FL7 A;  5BNQ R;  3URF Z; 
#chains in the Genus database with same CATH homology
 4KGG C;  4FHQ A;  4MSV B;  1JMA B;  3MBW A;  4YN0 A;  3U3T A;  2X10 A;  3ME4 A;  3U3P A;  4RSU D;  3U3Q A;  4E4D R;  3BUK C;  4GIQ R;  3QBQ B;  3K51 B;  4M4R A;  3X3F A;  3MHD D;  4OD2 S;  1D0G R;  1DU3 A;  5CIR E;  5IHL A;  4BK4 A;  3MI8 D;  1EXT A;  1ZA3 R;  4I9X C;  4N90 R;  1D4V A;  2UWI A;  1FT4 A;  3U3V A;  3WVT A;  3TJE F;  4M4P A;  2AW2 B;  3THM F;  3U3S A;  2HEV R;  5L36 B;  2HEY R;  2H9G R;  4KGQ C;  4BK5 A;  1NCF A;  4MXW R;  1SG1 X;  3ALQ R;  3IJ2 X;  4J6G C;  1TNR R;  5DMJ A;  3QD6 R;  3ME2 R;  3QO4 A;  3FL7 A;  5BNQ R;  3URF Z; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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