3TJEF

Crystal structure of fas receptor extracellular domain in complex with fab e09
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
109
structure length
100
Chain Sequence
DGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTCTLTSNT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Fab E09, light chain
total genus 18
structure length 100
sequence length 109
ec nomenclature
pdb deposition date 2011-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3tjeF02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3tjeF01
4J6GC 3U3TA 1D0GR 5BNQR 1TNRR 3FL7A 2X10A 3ME2R 5L36B 2H9GR 1ZA3R 4MSVB 5CIRE 3IJ2X 4N90R 5DMJA 1DU3A 1NCFA 3QBQB 3QO4A 1EXTA 3BUKC 5IHLA 1SG1X 4I9XC 4BK5A 3MBWA 4KGGC 4RSUD 3ME4A 3U3VA 2HEYR 1D4VA 4YN0A 3ALQR 3U3PA 1FT4A 2UWIA 3QD6R 4KGQC 4OD2S 1JMAB 4M4PA 3TJEF 3WVTA 2AW2B 4FHQA 4M4RA 4E4DR 3U3SA 4MXWR 3URFZ 2HEVR 3X3FA 3MHDD 3MI8D 4GIQR 3K51B 4BK4A 3U3QA 3THMF
chains in the Genus database with same CATH superfamily
4J6GC 3U3TA 1D0GR 5BNQR 1TNRR 2E4WA 3FL7A 2X10A 3ME2R 5L36B 2H9GR 1ZA3R 2E4VA 2E4XA 4MSVB 5CIRE 3IJ2X 4N90R 5DMJA 1DU3A 1NCFA 3QBQB 3QO4A 1EXTA 3BUKC 5IHLA 1SG1X 2QR6A 4I9XC 3MBWA 4KGGC 4BK5A 4RSUD 3ME4A 3U3VA 2HEYR 1D4VA 4YN0A 3ALQR 3U3PA 1FT4A 2E4YA 2UWIA 3QD6R 4KGQC 4OD2S 1JMAB 4M4PA 3TJEF 3WVTA 2AW2B 4FHQA 4M4RA 4E4DR 3U3SA 4MXWR 2E4UA 3URFZ 2HEVR 3X3FA 3MHDD 3MI8D 4GIQR 3K51B 4BK4A 3U3QA 3THMF
chains in the Genus database with same CATH topology
4J6GC 3U3TA 1D0GR 5BNQR 1TNRR 3FL7A 2X10A 3ME2R 5L36B 2H9GR 1ZA3R 4MSVB 5CIRE 3IJ2X 4N90R 5DMJA 1DU3A 1NCFA 3QBQB 3QO4A 1EXTA 3BUKC 5IHLA 1SG1X 4I9XC 4BK5A 3MBWA 4KGGC 4RSUD 3ME4A 3U3VA 2HEYR 1D4VA 4YN0A 3ALQR 3U3PA 1FT4A 2UWIA 3QD6R 4KGQC 4OD2S 1JMAB 4M4PA 3TJEF 3WVTA 2AW2B 4FHQA 4M4RA 4E4DR 3U3SA 4MXWR 3URFZ 2HEVR 3X3FA 3MHDD 3MI8D 4GIQR 3K51B 4BK4A 3U3QA 3THMF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J6G C;  3U3T A;  1D0G R;  5BNQ R;  1TNR R;  3FL7 A;  2X10 A;  3ME2 R;  5L36 B;  2H9G R;  1ZA3 R;  4MSV B;  5CIR E;  3IJ2 X;  4N90 R;  5DMJ A;  1DU3 A;  1NCF A;  3QBQ B;  3QO4 A;  1EXT A;  3BUK C;  5IHL A;  1SG1 X;  4I9X C;  4BK5 A;  3MBW A;  4KGG C;  4RSU D;  3ME4 A;  3U3V A;  2HEY R;  1D4V A;  4YN0 A;  3ALQ R;  3U3P A;  1FT4 A;  2UWI A;  3QD6 R;  4KGQ C;  4OD2 S;  1JMA B;  4M4P A;  3TJE F;  3WVT A;  2AW2 B;  4FHQ A;  4M4R A;  4E4D R;  3U3S A;  4MXW R;  3URF Z;  2HEV R;  3X3F A;  3MHD D;  3MI8 D;  4GIQ R;  3K51 B;  4BK4 A;  3U3Q A;  3THM F; 
#chains in the Genus database with same CATH topology
 4J6G C;  3U3T A;  1D0G R;  5BNQ R;  1TNR R;  2E4W A;  3FL7 A;  2X10 A;  3ME2 R;  5L36 B;  2H9G R;  1ZA3 R;  2E4V A;  2E4X A;  4MSV B;  5CIR E;  3IJ2 X;  4N90 R;  5DMJ A;  1DU3 A;  1NCF A;  3QBQ B;  3QO4 A;  1EXT A;  3BUK C;  5IHL A;  1SG1 X;  2QR6 A;  4I9X C;  3MBW A;  4KGG C;  4BK5 A;  4RSU D;  3ME4 A;  3U3V A;  2HEY R;  1D4V A;  4YN0 A;  3ALQ R;  3U3P A;  1FT4 A;  2E4Y A;  2UWI A;  3QD6 R;  4KGQ C;  4OD2 S;  1JMA B;  4M4P A;  3TJE F;  3WVT A;  2AW2 B;  4FHQ A;  4M4R A;  4E4D R;  3U3S A;  4MXW R;  2E4U A;  3URF Z;  2HEV R;  3X3F A;  3MHD D;  3MI8 D;  4GIQ R;  3K51 B;  4BK4 A;  3U3Q A;  3THM F; 
#chains in the Genus database with same CATH homology
 4J6G C;  3U3T A;  1D0G R;  5BNQ R;  1TNR R;  3FL7 A;  2X10 A;  3ME2 R;  5L36 B;  2H9G R;  1ZA3 R;  4MSV B;  5CIR E;  3IJ2 X;  4N90 R;  5DMJ A;  1DU3 A;  1NCF A;  3QBQ B;  3QO4 A;  1EXT A;  3BUK C;  5IHL A;  1SG1 X;  4I9X C;  4BK5 A;  3MBW A;  4KGG C;  4RSU D;  3ME4 A;  3U3V A;  2HEY R;  1D4V A;  4YN0 A;  3ALQ R;  3U3P A;  1FT4 A;  2UWI A;  3QD6 R;  4KGQ C;  4OD2 S;  1JMA B;  4M4P A;  3TJE F;  3WVT A;  2AW2 B;  4FHQ A;  4M4R A;  4E4D R;  3U3S A;  4MXW R;  3URF Z;  2HEV R;  3X3F A;  3MHD D;  3MI8 D;  4GIQ R;  3K51 B;  4BK4 A;  3U3Q A;  3THM F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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