4FHQA

Crystal structure of hvem
Total Genus 18

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
103
structure length
101
Chain Sequence
LPSCKEDEYPVGSECCPKCSPGYRVKEACGTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAY

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYO1 (4-15)S1 (8-11)TI1 (5-8)S2 (14-17)TIV1 (29-34)O2 (16-29)S3 (23-27)O4 (40-55)TII1 (20-23)S4 (36-39)S5 (44-45)O5 (58-73)TII2 (41-44)S6 (56-57)TI2 (74-77)O6 (61-81)3H1 (63-65)S8 (80-83)S10 (96-102)S7 (67-71)TVIII2 (69-72)S9 (87-93)TIV2 (92-95)TII3 (84-87)Updating...
connected with : NaN
publication title Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
pubmed doi rcsb
molecule keywords Tumor necrosis factor receptor superfamily member 14
molecule tags Immune system
source organism Homo sapiens
total genus 18
structure length 101
sequence length 103
ec nomenclature
pdb deposition date 2012-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA02
1D4VA 3U3VA 1FT4A 1SG1X 5IHLA 3U3TA 3K51B 3URFZ 1D0GR 1JMAB 3THMF 1EXTA 3QD6R 3U3QA 4OD2S 2X10A 3FL7A 5BNQR 3U3PA 1NCFA 5L36B 2UWIA 4M4RA 5CIRE 2HEYR 4FHQA 1DU3A 3ALQR 3BUKC 4MSVB 4KGGC 3WVTA 3MHDD 2H9GR 4GIQR 4M4PA 4RSUD 4E4DR 3ME4A 3MI8D 4KGQC 1TNRR 3MBWA 4MXWR 3QO4A 4N90R 5DMJA 3U3SA 4YN0A 1ZA3R 3X3FA 2HEVR 3QBQB 4I9XC 2AW2B 3IJ2X 3ME2R 4BK4A 4J6GC 4BK5A 3TJEF
chains in the Genus database with same CATH superfamily
1D4VA 3U3VA 1FT4A 1SG1X 5IHLA 3U3TA 3K51B 3URFZ 1D0GR 1JMAB 3THMF 2QR6A 1EXTA 3QD6R 3U3QA 4OD2S 2X10A 3FL7A 5BNQR 3U3PA 1NCFA 2E4VA 2E4XA 2E4UA 5L36B 2E4WA 2UWIA 4M4RA 5CIRE 2HEYR 4FHQA 1DU3A 3ALQR 3BUKC 4MSVB 4KGGC 3WVTA 3MHDD 2H9GR 4GIQR 4M4PA 4RSUD 4E4DR 3ME4A 3MI8D 4KGQC 1TNRR 3MBWA 4MXWR 2E4YA 3QO4A 4N90R 5DMJA 4YN0A 1ZA3R 3U3SA 2HEVR 3QBQB 4I9XC 2AW2B 3X3FA 3IJ2X 3ME2R 4BK4A 4J6GC 4BK5A 3TJEF
chains in the Genus database with same CATH topology
1D4VA 3U3VA 1FT4A 1SG1X 5IHLA 3U3TA 3K51B 3URFZ 1D0GR 1JMAB 3THMF 1EXTA 3QD6R 3U3QA 4OD2S 2X10A 3FL7A 5BNQR 3U3PA 1NCFA 5L36B 2UWIA 4M4RA 5CIRE 2HEYR 4FHQA 1DU3A 3ALQR 3BUKC 4MSVB 4KGGC 3WVTA 3MHDD 2H9GR 4GIQR 4M4PA 4RSUD 4E4DR 3ME4A 3MI8D 4KGQC 1TNRR 3MBWA 4MXWR 3QO4A 4N90R 5DMJA 3U3SA 4YN0A 1ZA3R 3X3FA 2HEVR 3QBQB 4I9XC 2AW2B 3IJ2X 3ME2R 4BK4A 4J6GC 4BK5A 3TJEF
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1D4V A;  3U3V A;  1FT4 A;  1SG1 X;  5IHL A;  3U3T A;  3K51 B;  3URF Z;  1D0G R;  1JMA B;  3THM F;  1EXT A;  3QD6 R;  3U3Q A;  4OD2 S;  2X10 A;  3FL7 A;  5BNQ R;  3U3P A;  1NCF A;  5L36 B;  2UWI A;  4M4R A;  5CIR E;  2HEY R;  4FHQ A;  1DU3 A;  3ALQ R;  3BUK C;  4MSV B;  4KGG C;  3WVT A;  3MHD D;  2H9G R;  4GIQ R;  4M4P A;  4RSU D;  4E4D R;  3ME4 A;  3MI8 D;  4KGQ C;  1TNR R;  3MBW A;  4MXW R;  3QO4 A;  4N90 R;  5DMJ A;  3U3S A;  4YN0 A;  1ZA3 R;  3X3F A;  2HEV R;  3QBQ B;  4I9X C;  2AW2 B;  3IJ2 X;  3ME2 R;  4BK4 A;  4J6G C;  4BK5 A;  3TJE F; 
#chains in the Genus database with same CATH topology
 1D4V A;  3U3V A;  1FT4 A;  1SG1 X;  5IHL A;  3U3T A;  3K51 B;  3URF Z;  1D0G R;  1JMA B;  3THM F;  2QR6 A;  1EXT A;  3QD6 R;  3U3Q A;  4OD2 S;  2X10 A;  3FL7 A;  5BNQ R;  3U3P A;  1NCF A;  2E4V A;  2E4X A;  2E4U A;  5L36 B;  2E4W A;  2UWI A;  4M4R A;  5CIR E;  2HEY R;  4FHQ A;  1DU3 A;  3ALQ R;  3BUK C;  4MSV B;  4KGG C;  3WVT A;  3MHD D;  2H9G R;  4GIQ R;  4M4P A;  4RSU D;  4E4D R;  3ME4 A;  3MI8 D;  4KGQ C;  1TNR R;  3MBW A;  4MXW R;  2E4Y A;  3QO4 A;  4N90 R;  5DMJ A;  4YN0 A;  1ZA3 R;  3U3S A;  2HEV R;  3QBQ B;  4I9X C;  2AW2 B;  3X3F A;  3IJ2 X;  3ME2 R;  4BK4 A;  4J6G C;  4BK5 A;  3TJE F; 
#chains in the Genus database with same CATH homology
 1D4V A;  3U3V A;  1FT4 A;  1SG1 X;  5IHL A;  3U3T A;  3K51 B;  3URF Z;  1D0G R;  1JMA B;  3THM F;  1EXT A;  3QD6 R;  3U3Q A;  4OD2 S;  2X10 A;  3FL7 A;  5BNQ R;  3U3P A;  1NCF A;  5L36 B;  2UWI A;  4M4R A;  5CIR E;  2HEY R;  4FHQ A;  1DU3 A;  3ALQ R;  3BUK C;  4MSV B;  4KGG C;  3WVT A;  3MHD D;  2H9G R;  4GIQ R;  4M4P A;  4RSU D;  4E4D R;  3ME4 A;  3MI8 D;  4KGQ C;  1TNR R;  3MBW A;  4MXW R;  3QO4 A;  4N90 R;  5DMJ A;  3U3S A;  4YN0 A;  1ZA3 R;  3X3F A;  2HEV R;  3QBQ B;  4I9X C;  2AW2 B;  3IJ2 X;  3ME2 R;  4BK4 A;  4J6G C;  4BK5 A;  3TJE F;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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