4FHQA

Crystal structure of hvem
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
103
structure length
101
Chain Sequence
LPSCKEDEYPVGSECCPKCSPGYRVKEACGTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 14
total genus 18
structure length 101
sequence length 103
ec nomenclature
pdb deposition date 2012-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA02
2HEVR 3IJ2X 4M4PA 3QD6R 4MSVB 4YN0A 1FT4A 1TNRR 3U3SA 3QO4A 3QBQB 3BUKC 4KGQC 2HEYR 4OD2S 1SG1X 3X3FA 3WVTA 4BK4A 3U3VA 3K51B 3MHDD 3MI8D 4FHQA 3MBWA 4I9XC 2X10A 3U3QA 3URFZ 5DMJA 1DU3A 3ME2R 4J6GC 3ME4A 2UWIA 4M4RA 4RSUD 4GIQR 1JMAB 2H9GR 1EXTA 3FL7A 4KGGC 3THMF 5BNQR 1NCFA 3TJEF 3U3TA 1ZA3R 2AW2B 4E4DR 1D4VA 5L36B 5CIRE 1D0GR 4N90R 3U3PA 4BK5A 5IHLA 3ALQR 4MXWR
chains in the Genus database with same CATH superfamily
2E4YA 2HEVR 3IJ2X 4M4PA 3QD6R 4MSVB 4YN0A 1FT4A 1TNRR 3U3SA 3QO4A 3QBQB 3BUKC 4KGQC 2HEYR 4OD2S 1SG1X 3X3FA 3WVTA 2E4WA 4BK4A 3U3VA 3K51B 3MHDD 3MI8D 4FHQA 3MBWA 4I9XC 2X10A 3U3QA 3URFZ 5DMJA 1DU3A 3ME2R 4J6GC 3ME4A 2UWIA 4M4RA 4RSUD 4GIQR 2QR6A 1JMAB 2H9GR 2E4XA 1EXTA 3FL7A 4KGGC 3THMF 5BNQR 1NCFA 3TJEF 3U3TA 1ZA3R 2AW2B 4E4DR 1D4VA 5L36B 5CIRE 1D0GR 2E4VA 4N90R 3U3PA 4BK5A 5IHLA 3ALQR 2E4UA 4MXWR
chains in the Genus database with same CATH topology
2HEVR 3IJ2X 4M4PA 3QD6R 4MSVB 4YN0A 1FT4A 1TNRR 3U3SA 3QO4A 3QBQB 3BUKC 4KGQC 2HEYR 4OD2S 1SG1X 3X3FA 3WVTA 4BK4A 3U3VA 3K51B 3MHDD 3MI8D 4FHQA 3MBWA 4I9XC 2X10A 3U3QA 3URFZ 5DMJA 1DU3A 3ME2R 4J6GC 3ME4A 2UWIA 4M4RA 4RSUD 4GIQR 1JMAB 2H9GR 1EXTA 3FL7A 4KGGC 3THMF 5BNQR 1NCFA 3TJEF 3U3TA 1ZA3R 2AW2B 4E4DR 1D4VA 5L36B 5CIRE 1D0GR 4N90R 3U3PA 4BK5A 5IHLA 3ALQR 4MXWR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HEV R;  3IJ2 X;  4M4P A;  3QD6 R;  4MSV B;  4YN0 A;  1FT4 A;  1TNR R;  3U3S A;  3QO4 A;  3QBQ B;  3BUK C;  4KGQ C;  2HEY R;  4OD2 S;  1SG1 X;  3X3F A;  3WVT A;  4BK4 A;  3U3V A;  3K51 B;  3MHD D;  3MI8 D;  4FHQ A;  3MBW A;  4I9X C;  2X10 A;  3U3Q A;  3URF Z;  5DMJ A;  1DU3 A;  3ME2 R;  4J6G C;  3ME4 A;  2UWI A;  4M4R A;  4RSU D;  4GIQ R;  1JMA B;  2H9G R;  1EXT A;  3FL7 A;  4KGG C;  3THM F;  5BNQ R;  1NCF A;  3TJE F;  3U3T A;  1ZA3 R;  2AW2 B;  4E4D R;  1D4V A;  5L36 B;  5CIR E;  1D0G R;  4N90 R;  3U3P A;  4BK5 A;  5IHL A;  3ALQ R;  4MXW R; 
#chains in the Genus database with same CATH topology
 2E4Y A;  2HEV R;  3IJ2 X;  4M4P A;  3QD6 R;  4MSV B;  4YN0 A;  1FT4 A;  1TNR R;  3U3S A;  3QO4 A;  3QBQ B;  3BUK C;  4KGQ C;  2HEY R;  4OD2 S;  1SG1 X;  3X3F A;  3WVT A;  2E4W A;  4BK4 A;  3U3V A;  3K51 B;  3MHD D;  3MI8 D;  4FHQ A;  3MBW A;  4I9X C;  2X10 A;  3U3Q A;  3URF Z;  5DMJ A;  1DU3 A;  3ME2 R;  4J6G C;  3ME4 A;  2UWI A;  4M4R A;  4RSU D;  4GIQ R;  2QR6 A;  1JMA B;  2H9G R;  2E4X A;  1EXT A;  3FL7 A;  4KGG C;  3THM F;  5BNQ R;  1NCF A;  3TJE F;  3U3T A;  1ZA3 R;  2AW2 B;  4E4D R;  1D4V A;  5L36 B;  5CIR E;  1D0G R;  2E4V A;  4N90 R;  3U3P A;  4BK5 A;  5IHL A;  3ALQ R;  2E4U A;  4MXW R; 
#chains in the Genus database with same CATH homology
 2HEV R;  3IJ2 X;  4M4P A;  3QD6 R;  4MSV B;  4YN0 A;  1FT4 A;  1TNR R;  3U3S A;  3QO4 A;  3QBQ B;  3BUK C;  4KGQ C;  2HEY R;  4OD2 S;  1SG1 X;  3X3F A;  3WVT A;  4BK4 A;  3U3V A;  3K51 B;  3MHD D;  3MI8 D;  4FHQ A;  3MBW A;  4I9X C;  2X10 A;  3U3Q A;  3URF Z;  5DMJ A;  1DU3 A;  3ME2 R;  4J6G C;  3ME4 A;  2UWI A;  4M4R A;  4RSU D;  4GIQ R;  1JMA B;  2H9G R;  1EXT A;  3FL7 A;  4KGG C;  3THM F;  5BNQ R;  1NCF A;  3TJE F;  3U3T A;  1ZA3 R;  2AW2 B;  4E4D R;  1D4V A;  5L36 B;  5CIR E;  1D0G R;  4N90 R;  3U3P A;  4BK5 A;  5IHL A;  3ALQ R;  4MXW R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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