4FHQA

Crystal structure of hvem
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
103
structure length
101
Chain Sequence
LPSCKEDEYPVGSECCPKCSPGYRVKEACGTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
pubmed doi rcsb
molecule keywords Tumor necrosis factor receptor superfamily member 14
molecule tags Immune system
source organism Homo sapiens
total genus 18
structure length 101
sequence length 103
ec nomenclature
pdb deposition date 2012-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA02
3IJ2X 3U3PA 4BK5A 2H9GR 3TJEF 3X3FA 2HEYR 2UWIA 2X10A 3MBWA 3FL7A 3MHDD 4RSUD 3URFZ 3WVTA 1SG1X 5BNQR 5DMJA 1FT4A 2HEVR 3K51B 4KGQC 4MSVB 5L36B 3ME4A 1JMAB 4N90R 5CIRE 4KGGC 4M4RA 4I9XC 3QBQB 3U3TA 4GIQR 3QD6R 1NCFA 4FHQA 1D4VA 1EXTA 4MXWR 4J6GC 4BK4A 3MI8D 4OD2S 1D0GR 3U3VA 5IHLA 3THMF 3U3SA 2AW2B 3ALQR 3ME2R 4M4PA 3U3QA 3BUKC 4E4DR 1DU3A 3QO4A 1ZA3R 4YN0A 1TNRR
chains in the Genus database with same CATH superfamily
3IJ2X 2E4UA 3U3PA 4BK5A 2H9GR 3TJEF 3X3FA 2HEYR 2UWIA 2X10A 3MBWA 3FL7A 3MHDD 4RSUD 3URFZ 2QR6A 3WVTA 1SG1X 5BNQR 5DMJA 1FT4A 2HEVR 3K51B 4KGQC 4MSVB 5L36B 3ME4A 1JMAB 4N90R 5CIRE 4KGGC 4M4RA 4I9XC 3QBQB 3U3TA 4GIQR 3QD6R 1NCFA 2E4XA 1D4VA 4FHQA 1EXTA 4MXWR 4J6GC 2E4WA 4BK4A 3MI8D 4OD2S 1D0GR 3U3VA 5IHLA 3THMF 2E4VA 2AW2B 3ALQR 2E4YA 3U3SA 3ME2R 4M4PA 3U3QA 3BUKC 4E4DR 1DU3A 3QO4A 1ZA3R 4YN0A 1TNRR
chains in the Genus database with same CATH topology
3IJ2X 3U3PA 4BK5A 2H9GR 3TJEF 3X3FA 2HEYR 2UWIA 2X10A 3MBWA 3FL7A 3MHDD 4RSUD 3URFZ 3WVTA 1SG1X 5BNQR 5DMJA 1FT4A 2HEVR 3K51B 4KGQC 4MSVB 5L36B 3ME4A 1JMAB 4N90R 5CIRE 4KGGC 4M4RA 4I9XC 3QBQB 3U3TA 4GIQR 3QD6R 1NCFA 4FHQA 1D4VA 1EXTA 4MXWR 4J6GC 4BK4A 3MI8D 4OD2S 1D0GR 3U3VA 5IHLA 3THMF 3U3SA 2AW2B 3ALQR 3ME2R 4M4PA 3U3QA 3BUKC 4E4DR 1DU3A 3QO4A 1ZA3R 4YN0A 1TNRR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IJ2 X;  3U3P A;  4BK5 A;  2H9G R;  3TJE F;  3X3F A;  2HEY R;  2UWI A;  2X10 A;  3MBW A;  3FL7 A;  3MHD D;  4RSU D;  3URF Z;  3WVT A;  1SG1 X;  5BNQ R;  5DMJ A;  1FT4 A;  2HEV R;  3K51 B;  4KGQ C;  4MSV B;  5L36 B;  3ME4 A;  1JMA B;  4N90 R;  5CIR E;  4KGG C;  4M4R A;  4I9X C;  3QBQ B;  3U3T A;  4GIQ R;  3QD6 R;  1NCF A;  4FHQ A;  1D4V A;  1EXT A;  4MXW R;  4J6G C;  4BK4 A;  3MI8 D;  4OD2 S;  1D0G R;  3U3V A;  5IHL A;  3THM F;  3U3S A;  2AW2 B;  3ALQ R;  3ME2 R;  4M4P A;  3U3Q A;  3BUK C;  4E4D R;  1DU3 A;  3QO4 A;  1ZA3 R;  4YN0 A;  1TNR R; 
#chains in the Genus database with same CATH topology
 3IJ2 X;  2E4U A;  3U3P A;  4BK5 A;  2H9G R;  3TJE F;  3X3F A;  2HEY R;  2UWI A;  2X10 A;  3MBW A;  3FL7 A;  3MHD D;  4RSU D;  3URF Z;  2QR6 A;  3WVT A;  1SG1 X;  5BNQ R;  5DMJ A;  1FT4 A;  2HEV R;  3K51 B;  4KGQ C;  4MSV B;  5L36 B;  3ME4 A;  1JMA B;  4N90 R;  5CIR E;  4KGG C;  4M4R A;  4I9X C;  3QBQ B;  3U3T A;  4GIQ R;  3QD6 R;  1NCF A;  2E4X A;  1D4V A;  4FHQ A;  1EXT A;  4MXW R;  4J6G C;  2E4W A;  4BK4 A;  3MI8 D;  4OD2 S;  1D0G R;  3U3V A;  5IHL A;  3THM F;  2E4V A;  2AW2 B;  3ALQ R;  2E4Y A;  3U3S A;  3ME2 R;  4M4P A;  3U3Q A;  3BUK C;  4E4D R;  1DU3 A;  3QO4 A;  1ZA3 R;  4YN0 A;  1TNR R; 
#chains in the Genus database with same CATH homology
 3IJ2 X;  3U3P A;  4BK5 A;  2H9G R;  3TJE F;  3X3F A;  2HEY R;  2UWI A;  2X10 A;  3MBW A;  3FL7 A;  3MHD D;  4RSU D;  3URF Z;  3WVT A;  1SG1 X;  5BNQ R;  5DMJ A;  1FT4 A;  2HEV R;  3K51 B;  4KGQ C;  4MSV B;  5L36 B;  3ME4 A;  1JMA B;  4N90 R;  5CIR E;  4KGG C;  4M4R A;  4I9X C;  3QBQ B;  3U3T A;  4GIQ R;  3QD6 R;  1NCF A;  4FHQ A;  1D4V A;  1EXT A;  4MXW R;  4J6G C;  4BK4 A;  3MI8 D;  4OD2 S;  1D0G R;  3U3V A;  5IHL A;  3THM F;  3U3S A;  2AW2 B;  3ALQ R;  3ME2 R;  4M4P A;  3U3Q A;  3BUK C;  4E4D R;  1DU3 A;  3QO4 A;  1ZA3 R;  4YN0 A;  1TNR R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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