4GIQR

Crystal structure of mouse rank bound to rankl
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
164
structure length
164
Chain Sequence
CTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWNSDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
pubmed doi rcsb
molecule keywords Tumor necrosis factor ligand superfamily member 11
molecule tags Protein binding/protein binding
source organism Mus musculus
total genus 27
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2012-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
R PF18278 RANK_CRD_2 Receptor activator of the NF-KB cysteine-rich repeat domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4giqR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4giqR01
4MSVB 2AW2B 3TJEF 3IJ2X 3X3FA 2HEVR 3U3SA 3MI8D 3MBWA 4I9XC 4KGGC 4RSUD 3U3PA 3U3TA 4YN0A 1JMAB 4BK5A 4GIQR 3U3QA 4J6GC 4M4PA 4FHQA 1NCFA 1TNRR 4M4RA 3QO4A 1D4VA 1EXTA 4BK4A 5L36B 3QBQB 1D0GR 3U3VA 5BNQR 2X10A 5CIRE 3QD6R 3ALQR 4N90R 5DMJA 1SG1X 3THMF 3BUKC 5IHLA 3ME4A 2H9GR 1DU3A 2UWIA 4MXWR 3WVTA 1ZA3R 3URFZ 4KGQC 3FL7A 4E4DR 3K51B 4OD2S 2HEYR 3MHDD 1FT4A 3ME2R
chains in the Genus database with same CATH superfamily
4MSVB 2AW2B 3TJEF 3IJ2X 3X3FA 2HEVR 3U3SA 3MI8D 3MBWA 4I9XC 4KGGC 4RSUD 2E4YA 2E4XA 3U3PA 3U3TA 4YN0A 1JMAB 4BK5A 4GIQR 2E4UA 2QR6A 3U3QA 4J6GC 4M4PA 4FHQA 2E4WA 1NCFA 1TNRR 4M4RA 3QO4A 1D4VA 1EXTA 4BK4A 5L36B 3QBQB 1D0GR 3U3VA 5BNQR 2X10A 5CIRE 3QD6R 3ALQR 4N90R 5DMJA 1SG1X 3THMF 3BUKC 5IHLA 2E4VA 3ME4A 2H9GR 1DU3A 2UWIA 4MXWR 3WVTA 1ZA3R 3URFZ 4KGQC 3FL7A 4E4DR 3K51B 4OD2S 2HEYR 3MHDD 1FT4A 3ME2R
chains in the Genus database with same CATH topology
4MSVB 2AW2B 3TJEF 3IJ2X 3X3FA 2HEVR 3U3SA 3MI8D 3MBWA 4I9XC 4KGGC 4RSUD 3U3PA 3U3TA 4YN0A 1JMAB 4BK5A 4GIQR 3U3QA 4J6GC 4M4PA 4FHQA 1NCFA 1TNRR 4M4RA 3QO4A 1D4VA 1EXTA 4BK4A 5L36B 3QBQB 1D0GR 3U3VA 5BNQR 2X10A 5CIRE 3QD6R 3ALQR 4N90R 5DMJA 1SG1X 3THMF 3BUKC 5IHLA 3ME4A 2H9GR 1DU3A 2UWIA 4MXWR 3WVTA 1ZA3R 3URFZ 4KGQC 3FL7A 4E4DR 3K51B 4OD2S 2HEYR 3MHDD 1FT4A 3ME2R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MSV B;  2AW2 B;  3TJE F;  3IJ2 X;  3X3F A;  2HEV R;  3U3S A;  3MI8 D;  3MBW A;  4I9X C;  4KGG C;  4RSU D;  3U3P A;  3U3T A;  4YN0 A;  1JMA B;  4BK5 A;  4GIQ R;  3U3Q A;  4J6G C;  4M4P A;  4FHQ A;  1NCF A;  1TNR R;  4M4R A;  3QO4 A;  1D4V A;  1EXT A;  4BK4 A;  5L36 B;  3QBQ B;  1D0G R;  3U3V A;  5BNQ R;  2X10 A;  5CIR E;  3QD6 R;  3ALQ R;  4N90 R;  5DMJ A;  1SG1 X;  3THM F;  3BUK C;  5IHL A;  3ME4 A;  2H9G R;  1DU3 A;  2UWI A;  4MXW R;  3WVT A;  1ZA3 R;  3URF Z;  4KGQ C;  3FL7 A;  4E4D R;  3K51 B;  4OD2 S;  2HEY R;  3MHD D;  1FT4 A;  3ME2 R; 
#chains in the Genus database with same CATH topology
 4MSV B;  2AW2 B;  3TJE F;  3IJ2 X;  3X3F A;  2HEV R;  3U3S A;  3MI8 D;  3MBW A;  4I9X C;  4KGG C;  4RSU D;  2E4Y A;  2E4X A;  3U3P A;  3U3T A;  4YN0 A;  1JMA B;  4BK5 A;  4GIQ R;  2E4U A;  2QR6 A;  3U3Q A;  4J6G C;  4M4P A;  4FHQ A;  2E4W A;  1NCF A;  1TNR R;  4M4R A;  3QO4 A;  1D4V A;  1EXT A;  4BK4 A;  5L36 B;  3QBQ B;  1D0G R;  3U3V A;  5BNQ R;  2X10 A;  5CIR E;  3QD6 R;  3ALQ R;  4N90 R;  5DMJ A;  1SG1 X;  3THM F;  3BUK C;  5IHL A;  2E4V A;  3ME4 A;  2H9G R;  1DU3 A;  2UWI A;  4MXW R;  3WVT A;  1ZA3 R;  3URF Z;  4KGQ C;  3FL7 A;  4E4D R;  3K51 B;  4OD2 S;  2HEY R;  3MHD D;  1FT4 A;  3ME2 R; 
#chains in the Genus database with same CATH homology
 4MSV B;  2AW2 B;  3TJE F;  3IJ2 X;  3X3F A;  2HEV R;  3U3S A;  3MI8 D;  3MBW A;  4I9X C;  4KGG C;  4RSU D;  3U3P A;  3U3T A;  4YN0 A;  1JMA B;  4BK5 A;  4GIQ R;  3U3Q A;  4J6G C;  4M4P A;  4FHQ A;  1NCF A;  1TNR R;  4M4R A;  3QO4 A;  1D4V A;  1EXT A;  4BK4 A;  5L36 B;  3QBQ B;  1D0G R;  3U3V A;  5BNQ R;  2X10 A;  5CIR E;  3QD6 R;  3ALQ R;  4N90 R;  5DMJ A;  1SG1 X;  3THM F;  3BUK C;  5IHL A;  3ME4 A;  2H9G R;  1DU3 A;  2UWI A;  4MXW R;  3WVT A;  1ZA3 R;  3URF Z;  4KGQ C;  3FL7 A;  4E4D R;  3K51 B;  4OD2 S;  2HEY R;  3MHD D;  1FT4 A;  3ME2 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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