4KGG | Genus

Total Genus 28

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	28
sequence length	165
structure length	165
Chain Sequence	TPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSTG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Cytokine/signaling protein
source organism	Homo sapiens
publication title	Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. pubmed doi rcsb
molecule keywords	Tumor necrosis factor receptor superfamily member 6B
total genus	28
structure length	165
sequence length	165
chains with identical sequence	D
ec nomenclature
pdb deposition date	2013-04-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00020	TNFR_c6	TNFR/NGFR cysteine-rich region

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.50.10	Mainly Beta	Ribbon	Tumor Necrosis Factor Receptor, subunit A; domain 2	Tumor Necrosis Factor Receptor, subunit A, domain 2	4kggC02
2.10.50.10	Mainly Beta	Ribbon	Tumor Necrosis Factor Receptor, subunit A; domain 2	Tumor Necrosis Factor Receptor, subunit A, domain 2	4kggC01

5DMJA 3QO4A 1ZA3R 3MHDD 3U3SA 3MI8D 3IJ2X 2AW2B 3QBQB 1D4VA 3X3FA 3URFZ 1NCFA 3U3QA 3U3VA 3K51B 2H9GR 4M4RA 4BK5A 3WVTA 3THMF 3BUKC 4N90R 5CIRE 3ALQR 4I9XC 1JMAB 3ME4A 4RSUD 4M4PA 3FL7A 4GIQR 1D0GR 5L36B 4OD2S 5IHLA 4MXWR 2X10A 4KGGC 2UWIA 1SG1X 3TJEF 3U3TA 3MBWA 2HEVR 3QD6R 4FHQA 4KGQC 1TNRR 1FT4A 2HEYR 1EXTA 1DU3A 3U3PA 4BK4A 4J6GC 4E4DR 5BNQR 4MSVB 4YN0A 3ME2R
chains in the Genus database with same CATH superfamily

5DMJA 3QO4A 1ZA3R 3MHDD 3U3SA 3MI8D 3IJ2X 2AW2B 3QBQB 1D4VA 3X3FA 3URFZ 1NCFA 3U3QA 3U3VA 3K51B 2E4VA 2H9GR 4M4RA 4BK5A 3WVTA 3THMF 2E4WA 3BUKC 4N90R 2QR6A 5CIRE 3ALQR 4I9XC 1JMAB 3ME4A 4RSUD 4M4PA 3FL7A 4GIQR 1D0GR 5L36B 4OD2S 5IHLA 4MXWR 2X10A 2E4YA 4KGGC 1SG1X 2UWIA 3TJEF 3U3TA 3MBWA 2E4XA 2HEVR 3QD6R 4FHQA 1TNRR 1FT4A 2HEYR 1EXTA 1DU3A 4KGQC 3U3PA 4BK4A 4J6GC 2E4UA 4E4DR 5BNQR 4MSVB 4YN0A 3ME2R
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5DMJ A;  3QO4 A;  1ZA3 R;  3MHD D;  3U3S A;  3MI8 D;  3IJ2 X;  2AW2 B;  3QBQ B;  1D4V A;  3X3F A;  3URF Z;  1NCF A;  3U3Q A;  3U3V A;  3K51 B;  2H9G R;  4M4R A;  4BK5 A;  3WVT A;  3THM F;  3BUK C;  4N90 R;  5CIR E;  3ALQ R;  4I9X C;  1JMA B;  3ME4 A;  4RSU D;  4M4P A;  3FL7 A;  4GIQ R;  1D0G R;  5L36 B;  4OD2 S;  5IHL A;  4MXW R;  2X10 A;  4KGG C;  2UWI A;  1SG1 X;  3TJE F;  3U3T A;  3MBW A;  2HEV R;  3QD6 R;  4FHQ A;  4KGQ C;  1TNR R;  1FT4 A;  2HEY R;  1EXT A;  1DU3 A;  3U3P A;  4BK4 A;  4J6G C;  4E4D R;  5BNQ R;  4MSV B;  4YN0 A;  3ME2 R; 
#chains in the Genus database with same CATH topology
 5DMJ A;  3QO4 A;  1ZA3 R;  3MHD D;  3U3S A;  3MI8 D;  3IJ2 X;  2AW2 B;  3QBQ B;  1D4V A;  3X3F A;  3URF Z;  1NCF A;  3U3Q A;  3U3V A;  3K51 B;  2E4V A;  2H9G R;  4M4R A;  4BK5 A;  3WVT A;  3THM F;  2E4W A;  3BUK C;  4N90 R;  2QR6 A;  5CIR E;  3ALQ R;  4I9X C;  1JMA B;  3ME4 A;  4RSU D;  4M4P A;  3FL7 A;  4GIQ R;  1D0G R;  5L36 B;  4OD2 S;  5IHL A;  4MXW R;  2X10 A;  2E4Y A;  4KGG C;  1SG1 X;  2UWI A;  3TJE F;  3U3T A;  3MBW A;  2E4X A;  2HEV R;  3QD6 R;  4FHQ A;  1TNR R;  1FT4 A;  2HEY R;  1EXT A;  1DU3 A;  4KGQ C;  3U3P A;  4BK4 A;  4J6G C;  2E4U A;  4E4D R;  5BNQ R;  4MSV B;  4YN0 A;  3ME2 R; 
#chains in the Genus database with same CATH homology
 5DMJ A;  3QO4 A;  1ZA3 R;  3MHD D;  3U3S A;  3MI8 D;  3IJ2 X;  2AW2 B;  3QBQ B;  1D4V A;  3X3F A;  3URF Z;  1NCF A;  3U3Q A;  3U3V A;  3K51 B;  2H9G R;  4M4R A;  4BK5 A;  3WVT A;  3THM F;  3BUK C;  4N90 R;  5CIR E;  3ALQ R;  4I9X C;  1JMA B;  3ME4 A;  4RSU D;  4M4P A;  3FL7 A;  4GIQ R;  1D0G R;  5L36 B;  4OD2 S;  5IHL A;  4MXW R;  2X10 A;  4KGG C;  2UWI A;  1SG1 X;  3TJE F;  3U3T A;  3MBW A;  2HEV R;  3QD6 R;  4FHQ A;  4KGQ C;  1TNR R;  1FT4 A;  2HEY R;  1EXT A;  1DU3 A;  3U3P A;  4BK4 A;  4J6G C;  4E4D R;  5BNQ R;  4MSV B;  4YN0 A;  3ME2 R;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4KGGC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations