4KGGC

Crystal structure of light mutant2 and dcr3 complex
Total Genus 28

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
165
structure length
165
Chain Sequence
TPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSTG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTII1 (53-56)S2 (46-50)TIV1 (40-43)S3 (56-60)TIV2 (41-44)O3 (73-88)TII2 (74-77)O1 (49-62)S5 (77-78)TVIII1 (58-61)O2 (52-70)TI1 (63-66)O4 (91-105)S8 (112-115)TVIII2 (85-88)TI2 (96-99)S6 (89-90)O5 (95-113)TII3 (116-119)S7 (99-103)TVIII3 (101-104)S9 (119-122)S10 (125-128)TI3 (106-109)TII4 (133-136)TII5 (154-157)S11 (136-140)TIV3 (121-124)S13 (157-158)O8 (153-168)O7 (132-150)TI4 (143-146)TIV4 (163-166)S4 (69-72)S12 (149-152)TVIII4 (138-141)S1 (35-39)Updating...
connected with : NaN
publication title Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
pubmed doi rcsb
molecule keywords Tumor necrosis factor receptor superfamily member 6B
molecule tags Cytokine/signaling protein
source organism Homo sapiens
total genus 28
structure length 165
sequence length 165
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4kggC02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4kggC01
3K51B 4GIQR 3U3QA 3QO4A 3U3VA 2H9GR 3ALQR 5L36B 3URFZ 1FT4A 1DU3A 1D0GR 3MHDD 1ZA3R 1SG1X 1TNRR 4MSVB 3IJ2X 5DMJA 1JMAB 2X10A 3THMF 3U3SA 4I9XC 3MBWA 3X3FA 1EXTA 3MI8D 4FHQA 4N90R 4E4DR 5IHLA 4OD2S 5CIRE 4M4RA 4J6GC 4RSUD 3U3PA 3ME4A 1D4VA 1NCFA 4BK5A 3WVTA 4KGGC 4MXWR 4KGQC 5BNQR 3BUKC 3QD6R 4YN0A 3TJEF 3FL7A 2HEVR 3ME2R 3QBQB 2AW2B 4M4PA 2HEYR 4BK4A 2UWIA 3U3TA
chains in the Genus database with same CATH superfamily
3K51B 4GIQR 3U3QA 3QO4A 3U3VA 2H9GR 3ALQR 5L36B 3URFZ 1FT4A 1DU3A 1D0GR 2E4VA 3MHDD 1ZA3R 1SG1X 1TNRR 2E4YA 4MSVB 3IJ2X 5DMJA 1JMAB 2X10A 3THMF 3U3SA 4I9XC 2QR6A 3MBWA 3X3FA 1EXTA 3MI8D 4FHQA 4N90R 4E4DR 5IHLA 4OD2S 5CIRE 4M4RA 2E4WA 4J6GC 4RSUD 3U3PA 2E4XA 3ME4A 1D4VA 1NCFA 4BK5A 3WVTA 4KGGC 4MXWR 2E4UA 4KGQC 5BNQR 3BUKC 3QD6R 4YN0A 3TJEF 3FL7A 2HEVR 3ME2R 3QBQB 2AW2B 4M4PA 2HEYR 4BK4A 2UWIA 3U3TA
chains in the Genus database with same CATH topology
3K51B 4GIQR 3U3QA 3QO4A 3U3VA 2H9GR 3ALQR 5L36B 3URFZ 1FT4A 1DU3A 1D0GR 3MHDD 1ZA3R 1SG1X 1TNRR 4MSVB 3IJ2X 5DMJA 1JMAB 2X10A 3THMF 3U3SA 4I9XC 3MBWA 3X3FA 1EXTA 3MI8D 4FHQA 4N90R 4E4DR 5IHLA 4OD2S 5CIRE 4M4RA 4J6GC 4RSUD 3U3PA 3ME4A 1D4VA 1NCFA 4BK5A 3WVTA 4KGGC 4MXWR 4KGQC 5BNQR 3BUKC 3QD6R 4YN0A 3TJEF 3FL7A 2HEVR 3ME2R 3QBQB 2AW2B 4M4PA 2HEYR 4BK4A 2UWIA 3U3TA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3K51 B;  4GIQ R;  3U3Q A;  3QO4 A;  3U3V A;  2H9G R;  3ALQ R;  5L36 B;  3URF Z;  1FT4 A;  1DU3 A;  1D0G R;  3MHD D;  1ZA3 R;  1SG1 X;  1TNR R;  4MSV B;  3IJ2 X;  5DMJ A;  1JMA B;  2X10 A;  3THM F;  3U3S A;  4I9X C;  3MBW A;  3X3F A;  1EXT A;  3MI8 D;  4FHQ A;  4N90 R;  4E4D R;  5IHL A;  4OD2 S;  5CIR E;  4M4R A;  4J6G C;  4RSU D;  3U3P A;  3ME4 A;  1D4V A;  1NCF A;  4BK5 A;  3WVT A;  4KGG C;  4MXW R;  4KGQ C;  5BNQ R;  3BUK C;  3QD6 R;  4YN0 A;  3TJE F;  3FL7 A;  2HEV R;  3ME2 R;  3QBQ B;  2AW2 B;  4M4P A;  2HEY R;  4BK4 A;  2UWI A;  3U3T A; 
#chains in the Genus database with same CATH topology
 3K51 B;  4GIQ R;  3U3Q A;  3QO4 A;  3U3V A;  2H9G R;  3ALQ R;  5L36 B;  3URF Z;  1FT4 A;  1DU3 A;  1D0G R;  2E4V A;  3MHD D;  1ZA3 R;  1SG1 X;  1TNR R;  2E4Y A;  4MSV B;  3IJ2 X;  5DMJ A;  1JMA B;  2X10 A;  3THM F;  3U3S A;  4I9X C;  2QR6 A;  3MBW A;  3X3F A;  1EXT A;  3MI8 D;  4FHQ A;  4N90 R;  4E4D R;  5IHL A;  4OD2 S;  5CIR E;  4M4R A;  2E4W A;  4J6G C;  4RSU D;  3U3P A;  2E4X A;  3ME4 A;  1D4V A;  1NCF A;  4BK5 A;  3WVT A;  4KGG C;  4MXW R;  2E4U A;  4KGQ C;  5BNQ R;  3BUK C;  3QD6 R;  4YN0 A;  3TJE F;  3FL7 A;  2HEV R;  3ME2 R;  3QBQ B;  2AW2 B;  4M4P A;  2HEY R;  4BK4 A;  2UWI A;  3U3T A; 
#chains in the Genus database with same CATH homology
 3K51 B;  4GIQ R;  3U3Q A;  3QO4 A;  3U3V A;  2H9G R;  3ALQ R;  5L36 B;  3URF Z;  1FT4 A;  1DU3 A;  1D0G R;  3MHD D;  1ZA3 R;  1SG1 X;  1TNR R;  4MSV B;  3IJ2 X;  5DMJ A;  1JMA B;  2X10 A;  3THM F;  3U3S A;  4I9X C;  3MBW A;  3X3F A;  1EXT A;  3MI8 D;  4FHQ A;  4N90 R;  4E4D R;  5IHL A;  4OD2 S;  5CIR E;  4M4R A;  4J6G C;  4RSU D;  3U3P A;  3ME4 A;  1D4V A;  1NCF A;  4BK5 A;  3WVT A;  4KGG C;  4MXW R;  4KGQ C;  5BNQ R;  3BUK C;  3QD6 R;  4YN0 A;  3TJE F;  3FL7 A;  2HEV R;  3ME2 R;  3QBQ B;  2AW2 B;  4M4P A;  2HEY R;  4BK4 A;  2UWI A;  3U3T A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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