4KGQC

Crystal structure of a human light loop mutant in complex with dcr3
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
167
structure length
167
Chain Sequence
TPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSTGHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 6B
total genus 32
structure length 167
sequence length 167
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4kgqC02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4kgqC01
2AW2B 3U3QA 1DU3A 1JMAB 3ALQR 3ME4A 3MI8D 4FHQA 3U3SA 4OD2S 2UWIA 3U3TA 4E4DR 4M4PA 1ZA3R 3IJ2X 1NCFA 3MBWA 3TJEF 5IHLA 3U3PA 3ME2R 4KGGC 1FT4A 3QBQB 3X3FA 5BNQR 3QD6R 4J6GC 3FL7A 4YN0A 4N90R 3QO4A 4BK4A 5L36B 4KGQC 4BK5A 3WVTA 5CIRE 5DMJA 2X10A 1EXTA 1D4VA 3K51B 4I9XC 4MXWR 3URFZ 1TNRR 4GIQR 3MHDD 3U3VA 2H9GR 3BUKC 3THMF 1D0GR 4MSVB 2HEVR 2HEYR 4RSUD 4M4RA 1SG1X
chains in the Genus database with same CATH superfamily
2QR6A 2AW2B 3U3QA 1DU3A 1JMAB 3ALQR 2E4XA 3ME4A 3MI8D 4FHQA 3U3SA 4OD2S 2E4VA 2UWIA 2E4UA 3U3TA 4M4PA 1ZA3R 4E4DR 2E4WA 3IJ2X 1NCFA 3MBWA 3TJEF 5IHLA 3U3PA 3ME2R 4KGGC 1FT4A 3QBQB 3X3FA 5BNQR 3QD6R 4J6GC 3FL7A 4YN0A 4N90R 3QO4A 4BK4A 5L36B 4KGQC 4BK5A 3WVTA 5CIRE 5DMJA 2X10A 1EXTA 1D4VA 3K51B 4I9XC 4MXWR 3URFZ 2E4YA 1TNRR 4GIQR 3MHDD 3U3VA 2H9GR 3BUKC 3THMF 1D0GR 4MSVB 2HEVR 2HEYR 4RSUD 4M4RA 1SG1X
chains in the Genus database with same CATH topology
2AW2B 3U3QA 1DU3A 1JMAB 3ALQR 3ME4A 3MI8D 4FHQA 3U3SA 4OD2S 2UWIA 3U3TA 4E4DR 4M4PA 1ZA3R 3IJ2X 1NCFA 3MBWA 3TJEF 5IHLA 3U3PA 3ME2R 4KGGC 1FT4A 3QBQB 3X3FA 5BNQR 3QD6R 4J6GC 3FL7A 4YN0A 4N90R 3QO4A 4BK4A 5L36B 4KGQC 4BK5A 3WVTA 5CIRE 5DMJA 2X10A 1EXTA 1D4VA 3K51B 4I9XC 4MXWR 3URFZ 1TNRR 4GIQR 3MHDD 3U3VA 2H9GR 3BUKC 3THMF 1D0GR 4MSVB 2HEVR 2HEYR 4RSUD 4M4RA 1SG1X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AW2 B;  3U3Q A;  1DU3 A;  1JMA B;  3ALQ R;  3ME4 A;  3MI8 D;  4FHQ A;  3U3S A;  4OD2 S;  2UWI A;  3U3T A;  4E4D R;  4M4P A;  1ZA3 R;  3IJ2 X;  1NCF A;  3MBW A;  3TJE F;  5IHL A;  3U3P A;  3ME2 R;  4KGG C;  1FT4 A;  3QBQ B;  3X3F A;  5BNQ R;  3QD6 R;  4J6G C;  3FL7 A;  4YN0 A;  4N90 R;  3QO4 A;  4BK4 A;  5L36 B;  4KGQ C;  4BK5 A;  3WVT A;  5CIR E;  5DMJ A;  2X10 A;  1EXT A;  1D4V A;  3K51 B;  4I9X C;  4MXW R;  3URF Z;  1TNR R;  4GIQ R;  3MHD D;  3U3V A;  2H9G R;  3BUK C;  3THM F;  1D0G R;  4MSV B;  2HEV R;  2HEY R;  4RSU D;  4M4R A;  1SG1 X; 
#chains in the Genus database with same CATH topology
 2QR6 A;  2AW2 B;  3U3Q A;  1DU3 A;  1JMA B;  3ALQ R;  2E4X A;  3ME4 A;  3MI8 D;  4FHQ A;  3U3S A;  4OD2 S;  2E4V A;  2UWI A;  2E4U A;  3U3T A;  4M4P A;  1ZA3 R;  4E4D R;  2E4W A;  3IJ2 X;  1NCF A;  3MBW A;  3TJE F;  5IHL A;  3U3P A;  3ME2 R;  4KGG C;  1FT4 A;  3QBQ B;  3X3F A;  5BNQ R;  3QD6 R;  4J6G C;  3FL7 A;  4YN0 A;  4N90 R;  3QO4 A;  4BK4 A;  5L36 B;  4KGQ C;  4BK5 A;  3WVT A;  5CIR E;  5DMJ A;  2X10 A;  1EXT A;  1D4V A;  3K51 B;  4I9X C;  4MXW R;  3URF Z;  2E4Y A;  1TNR R;  4GIQ R;  3MHD D;  3U3V A;  2H9G R;  3BUK C;  3THM F;  1D0G R;  4MSV B;  2HEV R;  2HEY R;  4RSU D;  4M4R A;  1SG1 X; 
#chains in the Genus database with same CATH homology
 2AW2 B;  3U3Q A;  1DU3 A;  1JMA B;  3ALQ R;  3ME4 A;  3MI8 D;  4FHQ A;  3U3S A;  4OD2 S;  2UWI A;  3U3T A;  4E4D R;  4M4P A;  1ZA3 R;  3IJ2 X;  1NCF A;  3MBW A;  3TJE F;  5IHL A;  3U3P A;  3ME2 R;  4KGG C;  1FT4 A;  3QBQ B;  3X3F A;  5BNQ R;  3QD6 R;  4J6G C;  3FL7 A;  4YN0 A;  4N90 R;  3QO4 A;  4BK4 A;  5L36 B;  4KGQ C;  4BK5 A;  3WVT A;  5CIR E;  5DMJ A;  2X10 A;  1EXT A;  1D4V A;  3K51 B;  4I9X C;  4MXW R;  3URF Z;  1TNR R;  4GIQ R;  3MHD D;  3U3V A;  2H9G R;  3BUK C;  3THM F;  1D0G R;  4MSV B;  2HEV R;  2HEY R;  4RSU D;  4M4R A;  1SG1 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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