4MXWR

Structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
169
structure length
149
Chain Sequence
CRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVEIAPCTSKRKTQCRCCCTHCELLSDCPPGTEAVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction.
pubmed doi rcsb
molecule tags Cytokine/immune system
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 3
total genus 22
structure length 149
sequence length 169
chains with identical sequence S
ec nomenclature
pdb deposition date 2013-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4mxwR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4mxwR01
5L36B 5DMJA 4RSUD 3K51B 3BUKC 1EXTA 3ME2R 3URFZ 2AW2B 4GIQR 3ME4A 4OD2S 2UWIA 3U3SA 3THMF 3WVTA 3QD6R 3MI8D 3MHDD 1NCFA 3U3VA 4BK4A 1FT4A 1ZA3R 4M4PA 3ALQR 4E4DR 1JMAB 3MBWA 4MSVB 3TJEF 4FHQA 2HEVR 3U3TA 2HEYR 3FL7A 4J6GC 5BNQR 2H9GR 1D0GR 4M4RA 3X3FA 1TNRR 5CIRE 4N90R 1SG1X 1D4VA 5IHLA 2X10A 4BK5A 4YN0A 1DU3A 4KGQC 3QBQB 3U3PA 3U3QA 4I9XC 4MXWR 3QO4A 3IJ2X 4KGGC
chains in the Genus database with same CATH superfamily
5L36B 5DMJA 4RSUD 3K51B 3BUKC 1EXTA 3ME2R 2E4WA 3URFZ 2AW2B 4GIQR 3ME4A 4OD2S 2UWIA 3U3SA 3THMF 3WVTA 3QD6R 3MI8D 3MHDD 1NCFA 3U3VA 2E4YA 4BK4A 1FT4A 1ZA3R 4M4PA 3ALQR 4E4DR 1JMAB 3MBWA 4MSVB 3TJEF 4FHQA 2HEVR 3U3TA 2HEYR 3FL7A 4J6GC 5BNQR 2H9GR 1D0GR 4M4RA 3X3FA 1TNRR 5CIRE 4N90R 1SG1X 1D4VA 5IHLA 2X10A 2E4XA 2E4VA 4BK5A 4YN0A 1DU3A 4KGQC 3QBQB 2QR6A 3U3PA 3U3QA 4I9XC 4MXWR 2E4UA 3QO4A 3IJ2X 4KGGC
chains in the Genus database with same CATH topology
5L36B 5DMJA 4RSUD 3K51B 3BUKC 1EXTA 3ME2R 3URFZ 2AW2B 4GIQR 3ME4A 4OD2S 2UWIA 3U3SA 3THMF 3WVTA 3QD6R 3MI8D 3MHDD 1NCFA 3U3VA 4BK4A 1FT4A 1ZA3R 4M4PA 3ALQR 4E4DR 1JMAB 3MBWA 4MSVB 3TJEF 4FHQA 2HEVR 3U3TA 2HEYR 3FL7A 4J6GC 5BNQR 2H9GR 1D0GR 4M4RA 3X3FA 1TNRR 5CIRE 4N90R 1SG1X 1D4VA 5IHLA 2X10A 4BK5A 4YN0A 1DU3A 4KGQC 3QBQB 3U3PA 3U3QA 4I9XC 4MXWR 3QO4A 3IJ2X 4KGGC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L36 B;  5DMJ A;  4RSU D;  3K51 B;  3BUK C;  1EXT A;  3ME2 R;  3URF Z;  2AW2 B;  4GIQ R;  3ME4 A;  4OD2 S;  2UWI A;  3U3S A;  3THM F;  3WVT A;  3QD6 R;  3MI8 D;  3MHD D;  1NCF A;  3U3V A;  4BK4 A;  1FT4 A;  1ZA3 R;  4M4P A;  3ALQ R;  4E4D R;  1JMA B;  3MBW A;  4MSV B;  3TJE F;  4FHQ A;  2HEV R;  3U3T A;  2HEY R;  3FL7 A;  4J6G C;  5BNQ R;  2H9G R;  1D0G R;  4M4R A;  3X3F A;  1TNR R;  5CIR E;  4N90 R;  1SG1 X;  1D4V A;  5IHL A;  2X10 A;  4BK5 A;  4YN0 A;  1DU3 A;  4KGQ C;  3QBQ B;  3U3P A;  3U3Q A;  4I9X C;  4MXW R;  3QO4 A;  3IJ2 X;  4KGG C; 
#chains in the Genus database with same CATH topology
 5L36 B;  5DMJ A;  4RSU D;  3K51 B;  3BUK C;  1EXT A;  3ME2 R;  2E4W A;  3URF Z;  2AW2 B;  4GIQ R;  3ME4 A;  4OD2 S;  2UWI A;  3U3S A;  3THM F;  3WVT A;  3QD6 R;  3MI8 D;  3MHD D;  1NCF A;  3U3V A;  2E4Y A;  4BK4 A;  1FT4 A;  1ZA3 R;  4M4P A;  3ALQ R;  4E4D R;  1JMA B;  3MBW A;  4MSV B;  3TJE F;  4FHQ A;  2HEV R;  3U3T A;  2HEY R;  3FL7 A;  4J6G C;  5BNQ R;  2H9G R;  1D0G R;  4M4R A;  3X3F A;  1TNR R;  5CIR E;  4N90 R;  1SG1 X;  1D4V A;  5IHL A;  2X10 A;  2E4X A;  2E4V A;  4BK5 A;  4YN0 A;  1DU3 A;  4KGQ C;  3QBQ B;  2QR6 A;  3U3P A;  3U3Q A;  4I9X C;  4MXW R;  2E4U A;  3QO4 A;  3IJ2 X;  4KGG C; 
#chains in the Genus database with same CATH homology
 5L36 B;  5DMJ A;  4RSU D;  3K51 B;  3BUK C;  1EXT A;  3ME2 R;  3URF Z;  2AW2 B;  4GIQ R;  3ME4 A;  4OD2 S;  2UWI A;  3U3S A;  3THM F;  3WVT A;  3QD6 R;  3MI8 D;  3MHD D;  1NCF A;  3U3V A;  4BK4 A;  1FT4 A;  1ZA3 R;  4M4P A;  3ALQ R;  4E4D R;  1JMA B;  3MBW A;  4MSV B;  3TJE F;  4FHQ A;  2HEV R;  3U3T A;  2HEY R;  3FL7 A;  4J6G C;  5BNQ R;  2H9G R;  1D0G R;  4M4R A;  3X3F A;  1TNR R;  5CIR E;  4N90 R;  1SG1 X;  1D4V A;  5IHL A;  2X10 A;  4BK5 A;  4YN0 A;  1DU3 A;  4KGQ C;  3QBQ B;  3U3P A;  3U3Q A;  4I9X C;  4MXW R;  3QO4 A;  3IJ2 X;  4KGG C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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