4YN0 | Genus

Total Genus 27

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	27
sequence length	168
structure length	168
Chain Sequence	SLPGTYRHVDRTTGQVLTCDKCPAGTYVSEHCTNMSLRVCSSCPAGTFTRHENGIERCHDCSQPCPWPMIERLPCAALTDRECICPPGMYQSNGTCAPHTVCPVGWGVRKKGTENEDVRCKQCARGTFSDVPSSVMKCKAHTDCLGQNLEVVKPGTKETDNVCGMRLF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 168 atoms

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168 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation. pubmed doi rcsb
molecule keywords	Tumor necrosis factor receptor superfamily member 21
molecule tags	Apoptosis/cell adhesion
source organism	Mus musculus
total genus	27
structure length	168
sequence length	168
ec nomenclature
pdb deposition date	2015-03-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00020	TNFR_c6	TNFR/NGFR cysteine-rich region

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.50.10	Mainly Beta	Ribbon	Tumor Necrosis Factor Receptor, subunit A; domain 2	Tumor Necrosis Factor Receptor, subunit A, domain 2	4yn0A02
2.10.50.10	Mainly Beta	Ribbon	Tumor Necrosis Factor Receptor, subunit A; domain 2	Tumor Necrosis Factor Receptor, subunit A, domain 2	4yn0A01

2UWIA 4M4PA 3BUKC 4FHQA 4M4RA 3WVTA 5DMJA 4GIQR 1FT4A 3QBQB 3TJEF 3IJ2X 3MHDD 4J6GC 4E4DR 1ZA3R 2AW2B 1EXTA 5L36B 5IHLA 1D4VA 3FL7A 3U3PA 3U3QA 3U3TA 3U3SA 3QO4A 1SG1X 4KGGC 2X10A 4N90R 3URFZ 5BNQR 1D0GR 4OD2S 3ME4A 4YN0A 1DU3A 4KGQC 5CIRE 3ALQR 3MI8D 1JMAB 3THMF 3U3VA 3X3FA 4BK4A 2HEYR 3QD6R 3MBWA 4BK5A 1TNRR 4RSUD 1NCFA 2H9GR 3K51B 4MXWR 4I9XC 4MSVB 2HEVR 3ME2R
chains in the Genus database with same CATH superfamily

2E4WA 2UWIA 4M4PA 3BUKC 4FHQA 2E4UA 4M4RA 3WVTA 5DMJA 4GIQR 1FT4A 2E4XA 3QBQB 3TJEF 3IJ2X 3MHDD 4J6GC 4E4DR 1ZA3R 2AW2B 1EXTA 5L36B 5IHLA 1D4VA 3FL7A 3U3PA 2E4VA 3U3QA 3U3TA 2E4YA 3U3SA 3QO4A 1SG1X 4KGGC 2X10A 4N90R 3URFZ 5BNQR 1D0GR 4OD2S 3ME4A 4YN0A 1DU3A 2QR6A 4KGQC 5CIRE 3ALQR 3MI8D 1JMAB 3THMF 3U3VA 3X3FA 4BK4A 2HEYR 3QD6R 3MBWA 4BK5A 1TNRR 4RSUD 1NCFA 2H9GR 3K51B 4MXWR 4I9XC 4MSVB 2HEVR 3ME2R
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2UWI A;  4M4P A;  3BUK C;  4FHQ A;  4M4R A;  3WVT A;  5DMJ A;  4GIQ R;  1FT4 A;  3QBQ B;  3TJE F;  3IJ2 X;  3MHD D;  4J6G C;  4E4D R;  1ZA3 R;  2AW2 B;  1EXT A;  5L36 B;  5IHL A;  1D4V A;  3FL7 A;  3U3P A;  3U3Q A;  3U3T A;  3U3S A;  3QO4 A;  1SG1 X;  4KGG C;  2X10 A;  4N90 R;  3URF Z;  5BNQ R;  1D0G R;  4OD2 S;  3ME4 A;  4YN0 A;  1DU3 A;  4KGQ C;  5CIR E;  3ALQ R;  3MI8 D;  1JMA B;  3THM F;  3U3V A;  3X3F A;  4BK4 A;  2HEY R;  3QD6 R;  3MBW A;  4BK5 A;  1TNR R;  4RSU D;  1NCF A;  2H9G R;  3K51 B;  4MXW R;  4I9X C;  4MSV B;  2HEV R;  3ME2 R; 
#chains in the Genus database with same CATH topology
 2E4W A;  2UWI A;  4M4P A;  3BUK C;  4FHQ A;  2E4U A;  4M4R A;  3WVT A;  5DMJ A;  4GIQ R;  1FT4 A;  2E4X A;  3QBQ B;  3TJE F;  3IJ2 X;  3MHD D;  4J6G C;  4E4D R;  1ZA3 R;  2AW2 B;  1EXT A;  5L36 B;  5IHL A;  1D4V A;  3FL7 A;  3U3P A;  2E4V A;  3U3Q A;  3U3T A;  2E4Y A;  3U3S A;  3QO4 A;  1SG1 X;  4KGG C;  2X10 A;  4N90 R;  3URF Z;  5BNQ R;  1D0G R;  4OD2 S;  3ME4 A;  4YN0 A;  1DU3 A;  2QR6 A;  4KGQ C;  5CIR E;  3ALQ R;  3MI8 D;  1JMA B;  3THM F;  3U3V A;  3X3F A;  4BK4 A;  2HEY R;  3QD6 R;  3MBW A;  4BK5 A;  1TNR R;  4RSU D;  1NCF A;  2H9G R;  3K51 B;  4MXW R;  4I9X C;  4MSV B;  2HEV R;  3ME2 R; 
#chains in the Genus database with same CATH homology
 2UWI A;  4M4P A;  3BUK C;  4FHQ A;  4M4R A;  3WVT A;  5DMJ A;  4GIQ R;  1FT4 A;  3QBQ B;  3TJE F;  3IJ2 X;  3MHD D;  4J6G C;  4E4D R;  1ZA3 R;  2AW2 B;  1EXT A;  5L36 B;  5IHL A;  1D4V A;  3FL7 A;  3U3P A;  3U3Q A;  3U3T A;  3U3S A;  3QO4 A;  1SG1 X;  4KGG C;  2X10 A;  4N90 R;  3URF Z;  5BNQ R;  1D0G R;  4OD2 S;  3ME4 A;  4YN0 A;  1DU3 A;  4KGQ C;  5CIR E;  3ALQ R;  3MI8 D;  1JMA B;  3THM F;  3U3V A;  3X3F A;  4BK4 A;  2HEY R;  3QD6 R;  3MBW A;  4BK5 A;  1TNR R;  4RSU D;  1NCF A;  2H9G R;  3K51 B;  4MXW R;  4I9X C;  4MSV B;  2HEV R;  3ME2 R;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4YN0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations