4YN0A

Crystal structure of app e2 domain in complex with dr6 crd domain
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
168
structure length
168
Chain Sequence
SLPGTYRHVDRTTGQVLTCDKCPAGTYVSEHCTNMSLRVCSSCPAGTFTRHENGIERCHDCSQPCPWPMIERLPCAALTDRECICPPGMYQSNGTCAPHTVCPVGWGVRKKGTENEDVRCKQCARGTFSDVPSSVMKCKAHTDCLGQNLEVVKPGTKETDNVCGMRLF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Apoptosis/cell adhesion
source organism Mus musculus
publication title The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.
pubmed doi rcsb
molecule keywords Tumor necrosis factor receptor superfamily member 21
total genus 27
structure length 168
sequence length 168
ec nomenclature
pdb deposition date 2015-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4yn0A02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4yn0A01
1DU3A 2HEVR 4E4DR 3MI8D 3MBWA 3U3TA 3U3PA 1JMAB 5CIRE 3THMF 3ME4A 4GIQR 2AW2B 4M4RA 3U3QA 3MHDD 3IJ2X 3QBQB 1FT4A 2HEYR 1D0GR 4FHQA 4MSVB 3ALQR 3K51B 3URFZ 5DMJA 1ZA3R 3ME2R 4N90R 1EXTA 4BK4A 2UWIA 3QO4A 1NCFA 3X3FA 1D4VA 3WVTA 5IHLA 5BNQR 5L36B 3TJEF 1SG1X 3QD6R 4KGQC 4YN0A 4M4PA 4J6GC 4KGGC 4OD2S 3U3SA 3BUKC 3FL7A 3U3VA 2X10A 4MXWR 1TNRR 4I9XC 4RSUD 4BK5A 2H9GR
chains in the Genus database with same CATH superfamily
1DU3A 2HEVR 4E4DR 3MI8D 3MBWA 3U3TA 2E4WA 1JMAB 5CIRE 3U3PA 3THMF 3ME4A 4GIQR 2AW2B 4M4RA 3U3QA 2E4UA 3MHDD 3IJ2X 4RSUD 3QBQB 1FT4A 2HEYR 1D0GR 4FHQA 4MSVB 3ALQR 3K51B 3URFZ 5DMJA 1ZA3R 2E4VA 3ME2R 4N90R 1EXTA 4BK4A 2UWIA 3QO4A 1NCFA 3X3FA 1D4VA 3WVTA 5IHLA 5BNQR 5L36B 3TJEF 1SG1X 3QD6R 4KGQC 4YN0A 4M4PA 4J6GC 4KGGC 4OD2S 3U3SA 3BUKC 2E4XA 3FL7A 3U3VA 2E4YA 2QR6A 2X10A 1TNRR 4I9XC 4MXWR 4BK5A 2H9GR
chains in the Genus database with same CATH topology
1DU3A 2HEVR 4E4DR 3MI8D 3MBWA 3U3TA 3U3PA 1JMAB 5CIRE 3THMF 3ME4A 4GIQR 2AW2B 4M4RA 3U3QA 3MHDD 3IJ2X 3QBQB 1FT4A 2HEYR 1D0GR 4FHQA 4MSVB 3ALQR 3K51B 3URFZ 5DMJA 1ZA3R 3ME2R 4N90R 1EXTA 4BK4A 2UWIA 3QO4A 1NCFA 3X3FA 1D4VA 3WVTA 5IHLA 5BNQR 5L36B 3TJEF 1SG1X 3QD6R 4KGQC 4YN0A 4M4PA 4J6GC 4KGGC 4OD2S 3U3SA 3BUKC 3FL7A 3U3VA 2X10A 4MXWR 1TNRR 4I9XC 4RSUD 4BK5A 2H9GR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DU3 A;  2HEV R;  4E4D R;  3MI8 D;  3MBW A;  3U3T A;  3U3P A;  1JMA B;  5CIR E;  3THM F;  3ME4 A;  4GIQ R;  2AW2 B;  4M4R A;  3U3Q A;  3MHD D;  3IJ2 X;  3QBQ B;  1FT4 A;  2HEY R;  1D0G R;  4FHQ A;  4MSV B;  3ALQ R;  3K51 B;  3URF Z;  5DMJ A;  1ZA3 R;  3ME2 R;  4N90 R;  1EXT A;  4BK4 A;  2UWI A;  3QO4 A;  1NCF A;  3X3F A;  1D4V A;  3WVT A;  5IHL A;  5BNQ R;  5L36 B;  3TJE F;  1SG1 X;  3QD6 R;  4KGQ C;  4YN0 A;  4M4P A;  4J6G C;  4KGG C;  4OD2 S;  3U3S A;  3BUK C;  3FL7 A;  3U3V A;  2X10 A;  4MXW R;  1TNR R;  4I9X C;  4RSU D;  4BK5 A;  2H9G R; 
#chains in the Genus database with same CATH topology
 1DU3 A;  2HEV R;  4E4D R;  3MI8 D;  3MBW A;  3U3T A;  2E4W A;  1JMA B;  5CIR E;  3U3P A;  3THM F;  3ME4 A;  4GIQ R;  2AW2 B;  4M4R A;  3U3Q A;  2E4U A;  3MHD D;  3IJ2 X;  4RSU D;  3QBQ B;  1FT4 A;  2HEY R;  1D0G R;  4FHQ A;  4MSV B;  3ALQ R;  3K51 B;  3URF Z;  5DMJ A;  1ZA3 R;  2E4V A;  3ME2 R;  4N90 R;  1EXT A;  4BK4 A;  2UWI A;  3QO4 A;  1NCF A;  3X3F A;  1D4V A;  3WVT A;  5IHL A;  5BNQ R;  5L36 B;  3TJE F;  1SG1 X;  3QD6 R;  4KGQ C;  4YN0 A;  4M4P A;  4J6G C;  4KGG C;  4OD2 S;  3U3S A;  3BUK C;  2E4X A;  3FL7 A;  3U3V A;  2E4Y A;  2QR6 A;  2X10 A;  1TNR R;  4I9X C;  4MXW R;  4BK5 A;  2H9G R; 
#chains in the Genus database with same CATH homology
 1DU3 A;  2HEV R;  4E4D R;  3MI8 D;  3MBW A;  3U3T A;  3U3P A;  1JMA B;  5CIR E;  3THM F;  3ME4 A;  4GIQ R;  2AW2 B;  4M4R A;  3U3Q A;  3MHD D;  3IJ2 X;  3QBQ B;  1FT4 A;  2HEY R;  1D0G R;  4FHQ A;  4MSV B;  3ALQ R;  3K51 B;  3URF Z;  5DMJ A;  1ZA3 R;  3ME2 R;  4N90 R;  1EXT A;  4BK4 A;  2UWI A;  3QO4 A;  1NCF A;  3X3F A;  1D4V A;  3WVT A;  5IHL A;  5BNQ R;  5L36 B;  3TJE F;  1SG1 X;  3QD6 R;  4KGQ C;  4YN0 A;  4M4P A;  4J6G C;  4KGG C;  4OD2 S;  3U3S A;  3BUK C;  3FL7 A;  3U3V A;  2X10 A;  4MXW R;  1TNR R;  4I9X C;  4RSU D;  4BK5 A;  2H9G R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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