5BNQR

Crystal structure of hrankl-mrank complex
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
166
structure length
166
Chain Sequence
PCTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWNSDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSSM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.
pubmed doi rcsb
molecule keywords Tumor necrosis factor ligand superfamily member 11
molecule tags Cytokine
source organism Homo sapiens
total genus 31
structure length 166
sequence length 166
ec nomenclature
pdb deposition date 2015-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
R PF18278 RANK_CRD_2 Receptor activator of the NF-KB cysteine-rich repeat domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 5bnqR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 5bnqR01
4N90R 3QBQB 3U3SA 4BK4A 3MI8D 5IHLA 2X10A 3TJEF 2HEVR 3MBWA 4BK5A 1ZA3R 4OD2S 4YN0A 1D0GR 3ALQR 5DMJA 3U3PA 3ME2R 1JMAB 4J6GC 3URFZ 5BNQR 1DU3A 3ME4A 3QO4A 4MXWR 2HEYR 4M4PA 1FT4A 3X3FA 3THMF 4E4DR 1TNRR 3BUKC 3IJ2X 2UWIA 4FHQA 4KGGC 4MSVB 1D4VA 4I9XC 4GIQR 4M4RA 4RSUD 5L36B 1SG1X 3U3QA 3U3VA 2H9GR 3MHDD 4KGQC 3WVTA 3U3TA 2AW2B 1NCFA 5CIRE 1EXTA 3QD6R 3K51B 3FL7A
chains in the Genus database with same CATH superfamily
4N90R 3QBQB 3U3SA 4BK4A 3MI8D 5IHLA 2X10A 3TJEF 2HEVR 3MBWA 4BK5A 1ZA3R 4OD2S 4YN0A 1D0GR 2E4UA 3ALQR 5DMJA 3U3PA 3ME2R 1JMAB 2E4YA 4J6GC 3URFZ 5BNQR 1DU3A 3ME4A 3QO4A 4MXWR 2HEYR 2QR6A 4M4PA 1FT4A 5CIRE 3X3FA 3THMF 4E4DR 1TNRR 3BUKC 3IJ2X 2UWIA 4FHQA 4KGGC 4MSVB 1D4VA 4I9XC 2E4XA 4GIQR 4M4RA 4RSUD 5L36B 1SG1X 3U3QA 3U3VA 2H9GR 3MHDD 4KGQC 2E4WA 3WVTA 3U3TA 2AW2B 1NCFA 2E4VA 1EXTA 3QD6R 3K51B 3FL7A
chains in the Genus database with same CATH topology
4N90R 3QBQB 3U3SA 4BK4A 3MI8D 5IHLA 2X10A 3TJEF 2HEVR 3MBWA 4BK5A 1ZA3R 4OD2S 4YN0A 1D0GR 3ALQR 5DMJA 3U3PA 3ME2R 1JMAB 4J6GC 3URFZ 5BNQR 1DU3A 3ME4A 3QO4A 4MXWR 2HEYR 4M4PA 1FT4A 3X3FA 3THMF 4E4DR 1TNRR 3BUKC 3IJ2X 2UWIA 4FHQA 4KGGC 4MSVB 1D4VA 4I9XC 4GIQR 4M4RA 4RSUD 5L36B 1SG1X 3U3QA 3U3VA 2H9GR 3MHDD 4KGQC 3WVTA 3U3TA 2AW2B 1NCFA 5CIRE 1EXTA 3QD6R 3K51B 3FL7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N90 R;  3QBQ B;  3U3S A;  4BK4 A;  3MI8 D;  5IHL A;  2X10 A;  3TJE F;  2HEV R;  3MBW A;  4BK5 A;  1ZA3 R;  4OD2 S;  4YN0 A;  1D0G R;  3ALQ R;  5DMJ A;  3U3P A;  3ME2 R;  1JMA B;  4J6G C;  3URF Z;  5BNQ R;  1DU3 A;  3ME4 A;  3QO4 A;  4MXW R;  2HEY R;  4M4P A;  1FT4 A;  3X3F A;  3THM F;  4E4D R;  1TNR R;  3BUK C;  3IJ2 X;  2UWI A;  4FHQ A;  4KGG C;  4MSV B;  1D4V A;  4I9X C;  4GIQ R;  4M4R A;  4RSU D;  5L36 B;  1SG1 X;  3U3Q A;  3U3V A;  2H9G R;  3MHD D;  4KGQ C;  3WVT A;  3U3T A;  2AW2 B;  1NCF A;  5CIR E;  1EXT A;  3QD6 R;  3K51 B;  3FL7 A; 
#chains in the Genus database with same CATH topology
 4N90 R;  3QBQ B;  3U3S A;  4BK4 A;  3MI8 D;  5IHL A;  2X10 A;  3TJE F;  2HEV R;  3MBW A;  4BK5 A;  1ZA3 R;  4OD2 S;  4YN0 A;  1D0G R;  2E4U A;  3ALQ R;  5DMJ A;  3U3P A;  3ME2 R;  1JMA B;  2E4Y A;  4J6G C;  3URF Z;  5BNQ R;  1DU3 A;  3ME4 A;  3QO4 A;  4MXW R;  2HEY R;  2QR6 A;  4M4P A;  1FT4 A;  5CIR E;  3X3F A;  3THM F;  4E4D R;  1TNR R;  3BUK C;  3IJ2 X;  2UWI A;  4FHQ A;  4KGG C;  4MSV B;  1D4V A;  4I9X C;  2E4X A;  4GIQ R;  4M4R A;  4RSU D;  5L36 B;  1SG1 X;  3U3Q A;  3U3V A;  2H9G R;  3MHD D;  4KGQ C;  2E4W A;  3WVT A;  3U3T A;  2AW2 B;  1NCF A;  2E4V A;  1EXT A;  3QD6 R;  3K51 B;  3FL7 A; 
#chains in the Genus database with same CATH homology
 4N90 R;  3QBQ B;  3U3S A;  4BK4 A;  3MI8 D;  5IHL A;  2X10 A;  3TJE F;  2HEV R;  3MBW A;  4BK5 A;  1ZA3 R;  4OD2 S;  4YN0 A;  1D0G R;  3ALQ R;  5DMJ A;  3U3P A;  3ME2 R;  1JMA B;  4J6G C;  3URF Z;  5BNQ R;  1DU3 A;  3ME4 A;  3QO4 A;  4MXW R;  2HEY R;  4M4P A;  1FT4 A;  3X3F A;  3THM F;  4E4D R;  1TNR R;  3BUK C;  3IJ2 X;  2UWI A;  4FHQ A;  4KGG C;  4MSV B;  1D4V A;  4I9X C;  4GIQ R;  4M4R A;  4RSU D;  5L36 B;  1SG1 X;  3U3Q A;  3U3V A;  2H9G R;  3MHD D;  4KGQ C;  3WVT A;  3U3T A;  2AW2 B;  1NCF A;  5CIR E;  1EXT A;  3QD6 R;  3K51 B;  3FL7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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