5DMJA

Structure of the extracellular domain of the cd40 in complex with 3h56-5 dab
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
165
structure length
165
Chain Sequence
TACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSDVSSAFEKCHPWTSCETKDLVVQQAGTDKTDVVCGP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
pubmed doi rcsb
molecule tags Immune system/signaling protein
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 5
total genus 21
structure length 165
sequence length 165
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 5dmjA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 5dmjA02
4BK5A 3THMF 3U3PA 1NCFA 5CIRE 4OD2S 2AW2B 3MI8D 2X10A 3TJEF 3URFZ 2H9GR 4M4RA 3U3TA 3QBQB 3U3SA 3X3FA 4RSUD 3ALQR 4MSVB 4KGQC 2HEVR 3U3VA 3MBWA 4E4DR 4J6GC 4GIQR 5DMJA 1FT4A 4MXWR 3MHDD 2HEYR 1DU3A 3ME4A 4YN0A 5L36B 1D0GR 3QD6R 3FL7A 3IJ2X 3U3QA 2UWIA 5IHLA 4FHQA 1EXTA 4I9XC 3K51B 4BK4A 1JMAB 3BUKC 4M4PA 5BNQR 1SG1X 3ME2R 4KGGC 1ZA3R 1TNRR 4N90R 3WVTA 3QO4A 1D4VA
chains in the Genus database with same CATH superfamily
4BK5A 3THMF 3U3PA 1NCFA 2QR6A 4OD2S 5CIRE 2AW2B 2E4WA 2X10A 3MI8D 3TJEF 3URFZ 2H9GR 4M4RA 3U3TA 3QBQB 3U3SA 3X3FA 4RSUD 3ALQR 4MSVB 4KGQC 2HEVR 3U3VA 3MBWA 4E4DR 2E4XA 4J6GC 4GIQR 5DMJA 1FT4A 4MXWR 3MHDD 2HEYR 1DU3A 3ME4A 4YN0A 5L36B 1D0GR 3QD6R 2E4UA 3FL7A 3IJ2X 3U3QA 2UWIA 5IHLA 4FHQA 1EXTA 4I9XC 3K51B 4BK4A 1JMAB 3BUKC 4M4PA 5BNQR 2E4YA 1SG1X 2E4VA 3ME2R 1ZA3R 1TNRR 4KGGC 4N90R 3WVTA 3QO4A 1D4VA
chains in the Genus database with same CATH topology
4BK5A 3THMF 3U3PA 1NCFA 5CIRE 4OD2S 2AW2B 3MI8D 2X10A 3TJEF 3URFZ 2H9GR 4M4RA 3U3TA 3QBQB 3U3SA 3X3FA 4RSUD 3ALQR 4MSVB 4KGQC 2HEVR 3U3VA 3MBWA 4E4DR 4J6GC 4GIQR 5DMJA 1FT4A 4MXWR 3MHDD 2HEYR 1DU3A 3ME4A 4YN0A 5L36B 1D0GR 3QD6R 3FL7A 3IJ2X 3U3QA 2UWIA 5IHLA 4FHQA 1EXTA 4I9XC 3K51B 4BK4A 1JMAB 3BUKC 4M4PA 5BNQR 1SG1X 3ME2R 4KGGC 1ZA3R 1TNRR 4N90R 3WVTA 3QO4A 1D4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BK5 A;  3THM F;  3U3P A;  1NCF A;  5CIR E;  4OD2 S;  2AW2 B;  3MI8 D;  2X10 A;  3TJE F;  3URF Z;  2H9G R;  4M4R A;  3U3T A;  3QBQ B;  3U3S A;  3X3F A;  4RSU D;  3ALQ R;  4MSV B;  4KGQ C;  2HEV R;  3U3V A;  3MBW A;  4E4D R;  4J6G C;  4GIQ R;  5DMJ A;  1FT4 A;  4MXW R;  3MHD D;  2HEY R;  1DU3 A;  3ME4 A;  4YN0 A;  5L36 B;  1D0G R;  3QD6 R;  3FL7 A;  3IJ2 X;  3U3Q A;  2UWI A;  5IHL A;  4FHQ A;  1EXT A;  4I9X C;  3K51 B;  4BK4 A;  1JMA B;  3BUK C;  4M4P A;  5BNQ R;  1SG1 X;  3ME2 R;  4KGG C;  1ZA3 R;  1TNR R;  4N90 R;  3WVT A;  3QO4 A;  1D4V A; 
#chains in the Genus database with same CATH topology
 4BK5 A;  3THM F;  3U3P A;  1NCF A;  2QR6 A;  4OD2 S;  5CIR E;  2AW2 B;  2E4W A;  2X10 A;  3MI8 D;  3TJE F;  3URF Z;  2H9G R;  4M4R A;  3U3T A;  3QBQ B;  3U3S A;  3X3F A;  4RSU D;  3ALQ R;  4MSV B;  4KGQ C;  2HEV R;  3U3V A;  3MBW A;  4E4D R;  2E4X A;  4J6G C;  4GIQ R;  5DMJ A;  1FT4 A;  4MXW R;  3MHD D;  2HEY R;  1DU3 A;  3ME4 A;  4YN0 A;  5L36 B;  1D0G R;  3QD6 R;  2E4U A;  3FL7 A;  3IJ2 X;  3U3Q A;  2UWI A;  5IHL A;  4FHQ A;  1EXT A;  4I9X C;  3K51 B;  4BK4 A;  1JMA B;  3BUK C;  4M4P A;  5BNQ R;  2E4Y A;  1SG1 X;  2E4V A;  3ME2 R;  1ZA3 R;  1TNR R;  4KGG C;  4N90 R;  3WVT A;  3QO4 A;  1D4V A; 
#chains in the Genus database with same CATH homology
 4BK5 A;  3THM F;  3U3P A;  1NCF A;  5CIR E;  4OD2 S;  2AW2 B;  3MI8 D;  2X10 A;  3TJE F;  3URF Z;  2H9G R;  4M4R A;  3U3T A;  3QBQ B;  3U3S A;  3X3F A;  4RSU D;  3ALQ R;  4MSV B;  4KGQ C;  2HEV R;  3U3V A;  3MBW A;  4E4D R;  4J6G C;  4GIQ R;  5DMJ A;  1FT4 A;  4MXW R;  3MHD D;  2HEY R;  1DU3 A;  3ME4 A;  4YN0 A;  5L36 B;  1D0G R;  3QD6 R;  3FL7 A;  3IJ2 X;  3U3Q A;  2UWI A;  5IHL A;  4FHQ A;  1EXT A;  4I9X C;  3K51 B;  4BK4 A;  1JMA B;  3BUK C;  4M4P A;  5BNQ R;  1SG1 X;  3ME2 R;  4KGG C;  1ZA3 R;  1TNR R;  4N90 R;  3WVT A;  3QO4 A;  1D4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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