5ERQA

Gephyrin e domain at 1.55 angstrom resolution
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
419
structure length
417
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 109
structure length 417
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5erqA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5erqA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5erqA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5erqA02
1O8QA 2IS8A 2G2CA 2X3LA 2NQKA 3TCRA 1O8OA 4CTAB 4PD0A 2NQSA 2QQ1A 1O8NA 1G8LA 1T3EA 5G2SA 4CT9A 2NQMA 3IWTA 3RFQA 4CTAA 5ERSA 1EAVA 4PD1A 5G2RA 1WU2A 3MCHA 2F7YA 4TK1A 5ERQA 2FU3A 1Y5EA 4TWGA 1G8RA 3MCJA 1DI6A 3MCIA 1R2KA 2NRSA 4UUWA 1DI7A 2NQQA 2NRPA 4CT8A 4UOCA 2NQVA 1IHCA 1UZ5A 5ERRA 1UUXA 4TK4A 2NQUA 3OI9A 5ERTA 4XCWA 2FTSA 1FC5A 1JLJA 1XI8A 4NWOA 4UUXA 2NQRA 2NROA 2PBQA 2F7WA 3PZYA 3KBQA 4U90A 1UUYA 4LHBA 2G4RA 4TK3A 3K6AA 4U91A 5ERUA 1MKZA 2NQNA 5ERVA
chains in the Genus database with same CATH superfamily
1O8QA 2IS8A 2G2CA 2X3LA 2NQKA 3TCRA 1O8OA 4CTAB 4PD0A 2NQSA 2QQ1A 1O8NA 1G8LA 1T3EA 5G2SA 4CT9A 2NQMA 3IWTA 3RFQA 4CTAA 5ERSA 1EAVA 5D6GA 4PD1A 1I6VD 5G2RA 1WU2A 3MCHA 2F7YA 4TK1A 5ERQA 2FU3A 1Y5EA 5DMHA 4TWGA 1G8RA 1IW7D 3MCJA 1YZYA 1DI6A 3MCIA 1R2KA 2NRSA 4UUWA 1DI7A 2NQQA 2NRPA 4CT8A 4UOCA 2NQVA 1IHCA 1UZ5A 5ERRA 1UUXA 4NWBA 4TK4A 2NQUA 3OI9A 5ERTA 4XCWA 2FTSA 3JSYA 1FC5A 1JLJA 3DQQA 1XI8A 4NWOA 4UUXA 2NQRA 2NROA 2PBQA 1HQMD 5D8HB 2F7WA 3PZYA 3KBQA 4U90A 1UUYA 4LHBA 2G4RA 4TK3A 3K6AA 4U91A 5ERUA 1MKZA 2NQNA 5ERVA
chains in the Genus database with same CATH topology
1O8QA 2IS8A 2G2CA 2X3LA 2NQKA 3TCRA 1O8OA 4CTAB 4PD0A 2NQSA 2QQ1A 1O8NA 1G8LA 1T3EA 5G2SA 4CT9A 2NQMA 3IWTA 3RFQA 4CTAA 5ERSA 1EAVA 5D6GA 4PD1A 1I6VD 5G2RA 1WU2A 3MCHA 2F7YA 4TK1A 5ERQA 2FU3A 1Y5EA 4TWGA 1G8RA 1IW7D 3MCJA 1DI6A 3MCIA 1R2KA 2NRSA 4UUWA 1DI7A 2NQQA 2NRPA 4CT8A 4UOCA 2NQVA 1IHCA 1UZ5A 5ERRA 1UUXA 4NWBA 4TK4A 2NQUA 3OI9A 5ERTA 4XCWA 2FTSA 3JSYA 1FC5A 1JLJA 1XI8A 4NWOA 4UUXA 2NQRA 2NROA 2PBQA 1HQMD 5D8HB 2F7WA 3PZYA 3KBQA 4U90A 1UUYA 4LHBA 2G4RA 4TK3A 3K6AA 4U91A 5ERUA 1MKZA 2NQNA 5ERVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O8Q A;  2IS8 A;  2G2C A;  2X3L A;  2NQK A;  3TCR A;  1O8O A;  4CTA B;  4PD0 A;  2NQS A;  2QQ1 A;  1O8N A;  1G8L A;  1T3E A;  5G2S A;  4CT9 A;  2NQM A;  3IWT A;  3RFQ A;  4CTA A;  5ERS A;  1EAV A;  4PD1 A;  5G2R A;  1WU2 A;  3MCH A;  2F7Y A;  4TK1 A;  5ERQ A;  2FU3 A;  1Y5E A;  4TWG A;  1G8R A;  3MCJ A;  1DI6 A;  3MCI A;  1R2K A;  2NRS A;  4UUW A;  1DI7 A;  2NQQ A;  2NRP A;  4CT8 A;  4UOC A;  2NQV A;  1IHC A;  1UZ5 A;  5ERR A;  1UUX A;  4TK4 A;  2NQU A;  3OI9 A;  5ERT A;  4XCW A;  2FTS A;  1FC5 A;  1JLJ A;  1XI8 A;  4NWO A;  4UUX A;  2NQR A;  2NRO A;  2PBQ A;  2F7W A;  3PZY A;  3KBQ A;  4U90 A;  1UUY A;  4LHB A;  2G4R A;  4TK3 A;  3K6A A;  4U91 A;  5ERU A;  1MKZ A;  2NQN A;  5ERV A; 
#chains in the Genus database with same CATH topology
 1O8Q A;  2IS8 A;  2G2C A;  2X3L A;  2NQK A;  3TCR A;  1O8O A;  4CTA B;  4PD0 A;  2NQS A;  2QQ1 A;  1O8N A;  1G8L A;  1T3E A;  5G2S A;  4CT9 A;  2NQM A;  3IWT A;  3RFQ A;  4CTA A;  5ERS A;  1EAV A;  5D6G A;  4PD1 A;  1I6V D;  5G2R A;  1WU2 A;  3MCH A;  2F7Y A;  4TK1 A;  5ERQ A;  2FU3 A;  1Y5E A;  5DMH A;  4TWG A;  1G8R A;  1IW7 D;  3MCJ A;  1YZY A;  1DI6 A;  3MCI A;  1R2K A;  2NRS A;  4UUW A;  1DI7 A;  2NQQ A;  2NRP A;  4CT8 A;  4UOC A;  2NQV A;  1IHC A;  1UZ5 A;  5ERR A;  1UUX A;  4NWB A;  4TK4 A;  2NQU A;  3OI9 A;  5ERT A;  4XCW A;  2FTS A;  3JSY A;  1FC5 A;  1JLJ A;  3DQQ A;  1XI8 A;  4NWO A;  4UUX A;  2NQR A;  2NRO A;  2PBQ A;  1HQM D;  5D8H B;  2F7W A;  3PZY A;  3KBQ A;  4U90 A;  1UUY A;  4LHB A;  2G4R A;  4TK3 A;  3K6A A;  4U91 A;  5ERU A;  1MKZ A;  2NQN A;  5ERV A; 
#chains in the Genus database with same CATH homology
 1O8Q A;  2IS8 A;  2G2C A;  2X3L A;  2NQK A;  3TCR A;  1O8O A;  4CTA B;  4PD0 A;  2NQS A;  2QQ1 A;  1O8N A;  1G8L A;  1T3E A;  5G2S A;  4CT9 A;  2NQM A;  3IWT A;  3RFQ A;  4CTA A;  5ERS A;  1EAV A;  5D6G A;  4PD1 A;  1I6V D;  5G2R A;  1WU2 A;  3MCH A;  2F7Y A;  4TK1 A;  5ERQ A;  2FU3 A;  1Y5E A;  4TWG A;  1G8R A;  1IW7 D;  3MCJ A;  1DI6 A;  3MCI A;  1R2K A;  2NRS A;  4UUW A;  1DI7 A;  2NQQ A;  2NRP A;  4CT8 A;  4UOC A;  2NQV A;  1IHC A;  1UZ5 A;  5ERR A;  1UUX A;  4NWB A;  4TK4 A;  2NQU A;  3OI9 A;  5ERT A;  4XCW A;  2FTS A;  3JSY A;  1FC5 A;  1JLJ A;  1XI8 A;  4NWO A;  4UUX A;  2NQR A;  2NRO A;  2PBQ A;  1HQM D;  5D8H B;  2F7W A;  3PZY A;  3KBQ A;  4U90 A;  1UUY A;  4LHB A;  2G4R A;  4TK3 A;  3K6A A;  4U91 A;  5ERU A;  1MKZ A;  2NQN A;  5ERV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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