5ERQA

Gephyrin e domain at 1.55 angstrom resolution
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
419
structure length
417
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 109
structure length 417
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5erqA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5erqA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5erqA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5erqA02
1JLJA 4LHBA 3TCRA 4TK3A 2PBQA 1MKZA 5ERVA 2QQ1A 2NQSA 4NWOA 3IWTA 2NQUA 2NRPA 4U90A 5ERTA 3MCJA 4PD0A 2NROA 2NQQA 3RFQA 2FU3A 3KBQA 1G8LA 1O8QA 1IHCA 4CTAA 1UUYA 1UZ5A 1WU2A 2IS8A 4TWGA 3MCHA 5ERSA 2F7YA 3K6AA 2X3LA 2NQNA 1DI6A 2NQMA 3OI9A 1O8NA 4XCWA 1UUXA 1O8OA 1EAVA 1G8RA 1T3EA 2NQKA 5ERRA 2G4RA 4UUWA 5G2RA 2NQRA 5ERUA 5ERQA 1FC5A 1XI8A 3MCIA 4TK4A 1R2KA 2NRSA 2FTSA 4UUXA 4PD1A 4UOCA 2F7WA 1DI7A 2G2CA 2NQVA 5G2SA 4CTAB 4CT9A 3PZYA 4TK1A 1Y5EA 4U91A 4CT8A
chains in the Genus database with same CATH superfamily
1JLJA 4LHBA 3TCRA 4TK3A 2PBQA 1MKZA 5ERVA 2QQ1A 2NQSA 4NWOA 3IWTA 2NQUA 2NRPA 5DMHA 4U90A 5ERTA 3MCJA 1YZYA 4PD0A 2NROA 2NQQA 3RFQA 2FU3A 3KBQA 1G8LA 1O8QA 1IHCA 4CTAA 1UUYA 1UZ5A 1WU2A 2IS8A 4TWGA 3MCHA 5ERSA 2F7YA 3K6AA 2X3LA 2NQNA 1IW7D 1DI6A 5D8HB 2NQMA 1I6VD 3OI9A 1O8NA 4XCWA 1UUXA 1O8OA 3JSYA 1EAVA 1G8RA 1T3EA 2NQKA 5ERRA 2G4RA 4UUWA 5G2RA 2NQRA 5ERUA 1HQMD 5ERQA 1FC5A 1XI8A 3DQQA 3MCIA 4TK4A 1R2KA 2NRSA 2FTSA 4NWBA 4UUXA 4PD1A 4UOCA 2F7WA 1DI7A 2G2CA 2NQVA 5G2SA 4CTAB 4CT9A 3PZYA 4TK1A 1Y5EA 4U91A 4CT8A 5D6GA
chains in the Genus database with same CATH topology
1JLJA 4LHBA 3TCRA 4TK3A 2PBQA 1MKZA 5ERVA 2QQ1A 2NQSA 4NWOA 3IWTA 2NQUA 2NRPA 4U90A 5ERTA 3MCJA 4PD0A 2NROA 2NQQA 3RFQA 2FU3A 3KBQA 1G8LA 1O8QA 1IHCA 4CTAA 1UUYA 1UZ5A 1WU2A 2IS8A 4TWGA 3MCHA 5ERSA 2F7YA 3K6AA 2X3LA 2NQNA 1IW7D 1DI6A 5D8HB 2NQMA 1I6VD 3OI9A 1O8NA 4XCWA 1UUXA 1O8OA 3JSYA 1EAVA 1G8RA 1T3EA 2NQKA 5ERRA 2G4RA 4UUWA 5G2RA 2NQRA 5ERUA 1HQMD 5ERQA 1FC5A 1XI8A 3MCIA 4TK4A 1R2KA 2NRSA 2FTSA 4NWBA 4UUXA 4PD1A 4UOCA 2F7WA 1DI7A 2G2CA 2NQVA 5G2SA 4CTAB 4CT9A 3PZYA 4TK1A 1Y5EA 4U91A 4CT8A 5D6GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JLJ A;  4LHB A;  3TCR A;  4TK3 A;  2PBQ A;  1MKZ A;  5ERV A;  2QQ1 A;  2NQS A;  4NWO A;  3IWT A;  2NQU A;  2NRP A;  4U90 A;  5ERT A;  3MCJ A;  4PD0 A;  2NRO A;  2NQQ A;  3RFQ A;  2FU3 A;  3KBQ A;  1G8L A;  1O8Q A;  1IHC A;  4CTA A;  1UUY A;  1UZ5 A;  1WU2 A;  2IS8 A;  4TWG A;  3MCH A;  5ERS A;  2F7Y A;  3K6A A;  2X3L A;  2NQN A;  1DI6 A;  2NQM A;  3OI9 A;  1O8N A;  4XCW A;  1UUX A;  1O8O A;  1EAV A;  1G8R A;  1T3E A;  2NQK A;  5ERR A;  2G4R A;  4UUW A;  5G2R A;  2NQR A;  5ERU A;  5ERQ A;  1FC5 A;  1XI8 A;  3MCI A;  4TK4 A;  1R2K A;  2NRS A;  2FTS A;  4UUX A;  4PD1 A;  4UOC A;  2F7W A;  1DI7 A;  2G2C A;  2NQV A;  5G2S A;  4CTA B;  4CT9 A;  3PZY A;  4TK1 A;  1Y5E A;  4U91 A;  4CT8 A; 
#chains in the Genus database with same CATH topology
 1JLJ A;  4LHB A;  3TCR A;  4TK3 A;  2PBQ A;  1MKZ A;  5ERV A;  2QQ1 A;  2NQS A;  4NWO A;  3IWT A;  2NQU A;  2NRP A;  5DMH A;  4U90 A;  5ERT A;  3MCJ A;  1YZY A;  4PD0 A;  2NRO A;  2NQQ A;  3RFQ A;  2FU3 A;  3KBQ A;  1G8L A;  1O8Q A;  1IHC A;  4CTA A;  1UUY A;  1UZ5 A;  1WU2 A;  2IS8 A;  4TWG A;  3MCH A;  5ERS A;  2F7Y A;  3K6A A;  2X3L A;  2NQN A;  1IW7 D;  1DI6 A;  5D8H B;  2NQM A;  1I6V D;  3OI9 A;  1O8N A;  4XCW A;  1UUX A;  1O8O A;  3JSY A;  1EAV A;  1G8R A;  1T3E A;  2NQK A;  5ERR A;  2G4R A;  4UUW A;  5G2R A;  2NQR A;  5ERU A;  1HQM D;  5ERQ A;  1FC5 A;  1XI8 A;  3DQQ A;  3MCI A;  4TK4 A;  1R2K A;  2NRS A;  2FTS A;  4NWB A;  4UUX A;  4PD1 A;  4UOC A;  2F7W A;  1DI7 A;  2G2C A;  2NQV A;  5G2S A;  4CTA B;  4CT9 A;  3PZY A;  4TK1 A;  1Y5E A;  4U91 A;  4CT8 A;  5D6G A; 
#chains in the Genus database with same CATH homology
 1JLJ A;  4LHB A;  3TCR A;  4TK3 A;  2PBQ A;  1MKZ A;  5ERV A;  2QQ1 A;  2NQS A;  4NWO A;  3IWT A;  2NQU A;  2NRP A;  4U90 A;  5ERT A;  3MCJ A;  4PD0 A;  2NRO A;  2NQQ A;  3RFQ A;  2FU3 A;  3KBQ A;  1G8L A;  1O8Q A;  1IHC A;  4CTA A;  1UUY A;  1UZ5 A;  1WU2 A;  2IS8 A;  4TWG A;  3MCH A;  5ERS A;  2F7Y A;  3K6A A;  2X3L A;  2NQN A;  1IW7 D;  1DI6 A;  5D8H B;  2NQM A;  1I6V D;  3OI9 A;  1O8N A;  4XCW A;  1UUX A;  1O8O A;  3JSY A;  1EAV A;  1G8R A;  1T3E A;  2NQK A;  5ERR A;  2G4R A;  4UUW A;  5G2R A;  2NQR A;  5ERU A;  1HQM D;  5ERQ A;  1FC5 A;  1XI8 A;  3MCI A;  4TK4 A;  1R2K A;  2NRS A;  2FTS A;  4NWB A;  4UUX A;  4PD1 A;  4UOC A;  2F7W A;  1DI7 A;  2G2C A;  2NQV A;  5G2S A;  4CTA B;  4CT9 A;  3PZY A;  4TK1 A;  1Y5E A;  4U91 A;  4CT8 A;  5D6G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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