5ERQA

Gephyrin e domain at 1.55 angstrom resolution
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
419
structure length
417
Chain Sequence
MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Rattus norvegicus
publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule keywords Gephyrin
total genus 109
structure length 417
sequence length 419
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5erqA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5erqA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5erqA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5erqA02
2NQRA 2F7WA 1O8NA 3MCJA 4CT9A 1Y5EA 1DI7A 1O8QA 4UUWA 4PD1A 2NQUA 2NQQA 2NRSA 2NQMA 2F7YA 2NQKA 2IS8A 1JLJA 1MKZA 4TK1A 2NRPA 3RFQA 3KBQA 1DI6A 2G4RA 5ERVA 4TK4A 4TK3A 1UUYA 4TWGA 3IWTA 4UOCA 2X3LA 2QQ1A 1FC5A 5ERUA 2NROA 1UUXA 1R2KA 1O8OA 1T3EA 5G2SA 1G8RA 2FU3A 4NWOA 2NQVA 3K6AA 3OI9A 5ERTA 4UUXA 3TCRA 2NQSA 2PBQA 1WU2A 2G2CA 1XI8A 4LHBA 1EAVA 5ERRA 1G8LA 4PD0A 4XCWA 3MCIA 4CTAA 2FTSA 5ERQA 3PZYA 4CTAB 3MCHA 2NQNA 1IHCA 4U90A 4CT8A 5ERSA 5G2RA 1UZ5A 4U91A
chains in the Genus database with same CATH superfamily
2NQRA 2F7WA 1O8NA 3MCJA 4CT9A 1Y5EA 1DI7A 1O8QA 4UUWA 4PD1A 2NQUA 2NQQA 1YZYA 2NRSA 2NQMA 2F7YA 2NQKA 2IS8A 1JLJA 5DMHA 1MKZA 4TK1A 2NRPA 1HQMD 3RFQA 3KBQA 1DI6A 2G4RA 5ERVA 4TK4A 4TK3A 1UUYA 4TWGA 3IWTA 4UOCA 5D6GA 5D8HB 3JSYA 2X3LA 2QQ1A 1FC5A 1I6VD 5ERUA 2NROA 1UUXA 3DQQA 1R2KA 1O8OA 4NWBA 1T3EA 5G2SA 1G8RA 2FU3A 4NWOA 2NQVA 3K6AA 3OI9A 1IW7D 5ERTA 4UUXA 3TCRA 2NQSA 2PBQA 1WU2A 2G2CA 1XI8A 4LHBA 1EAVA 5ERRA 1G8LA 4PD0A 4XCWA 3MCIA 4CTAA 2FTSA 5ERQA 3PZYA 4CTAB 3MCHA 2NQNA 1IHCA 4U90A 4CT8A 5ERSA 5G2RA 1UZ5A 4U91A
chains in the Genus database with same CATH topology
2NQRA 2F7WA 1O8NA 3MCJA 4CT9A 1Y5EA 1DI7A 1O8QA 4UUWA 4PD1A 2NQUA 2NQQA 2NRSA 2NQMA 2F7YA 2NQKA 2IS8A 1JLJA 1MKZA 4TK1A 2NRPA 1HQMD 3RFQA 3KBQA 1DI6A 2G4RA 5ERVA 4TK4A 4TK3A 1UUYA 4TWGA 3IWTA 4UOCA 5D6GA 5D8HB 3JSYA 2X3LA 2QQ1A 1FC5A 1I6VD 5ERUA 2NROA 1UUXA 1R2KA 1O8OA 4NWBA 1T3EA 5G2SA 1G8RA 2FU3A 4NWOA 2NQVA 3K6AA 3OI9A 1IW7D 5ERTA 4UUXA 3TCRA 2NQSA 2PBQA 1WU2A 2G2CA 1XI8A 4LHBA 1EAVA 5ERRA 1G8LA 4PD0A 4XCWA 3MCIA 4CTAA 2FTSA 5ERQA 3PZYA 4CTAB 3MCHA 2NQNA 1IHCA 4U90A 4CT8A 5ERSA 5G2RA 1UZ5A 4U91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NQR A;  2F7W A;  1O8N A;  3MCJ A;  4CT9 A;  1Y5E A;  1DI7 A;  1O8Q A;  4UUW A;  4PD1 A;  2NQU A;  2NQQ A;  2NRS A;  2NQM A;  2F7Y A;  2NQK A;  2IS8 A;  1JLJ A;  1MKZ A;  4TK1 A;  2NRP A;  3RFQ A;  3KBQ A;  1DI6 A;  2G4R A;  5ERV A;  4TK4 A;  4TK3 A;  1UUY A;  4TWG A;  3IWT A;  4UOC A;  2X3L A;  2QQ1 A;  1FC5 A;  5ERU A;  2NRO A;  1UUX A;  1R2K A;  1O8O A;  1T3E A;  5G2S A;  1G8R A;  2FU3 A;  4NWO A;  2NQV A;  3K6A A;  3OI9 A;  5ERT A;  4UUX A;  3TCR A;  2NQS A;  2PBQ A;  1WU2 A;  2G2C A;  1XI8 A;  4LHB A;  1EAV A;  5ERR A;  1G8L A;  4PD0 A;  4XCW A;  3MCI A;  4CTA A;  2FTS A;  5ERQ A;  3PZY A;  4CTA B;  3MCH A;  2NQN A;  1IHC A;  4U90 A;  4CT8 A;  5ERS A;  5G2R A;  1UZ5 A;  4U91 A; 
#chains in the Genus database with same CATH topology
 2NQR A;  2F7W A;  1O8N A;  3MCJ A;  4CT9 A;  1Y5E A;  1DI7 A;  1O8Q A;  4UUW A;  4PD1 A;  2NQU A;  2NQQ A;  1YZY A;  2NRS A;  2NQM A;  2F7Y A;  2NQK A;  2IS8 A;  1JLJ A;  5DMH A;  1MKZ A;  4TK1 A;  2NRP A;  1HQM D;  3RFQ A;  3KBQ A;  1DI6 A;  2G4R A;  5ERV A;  4TK4 A;  4TK3 A;  1UUY A;  4TWG A;  3IWT A;  4UOC A;  5D6G A;  5D8H B;  3JSY A;  2X3L A;  2QQ1 A;  1FC5 A;  1I6V D;  5ERU A;  2NRO A;  1UUX A;  3DQQ A;  1R2K A;  1O8O A;  4NWB A;  1T3E A;  5G2S A;  1G8R A;  2FU3 A;  4NWO A;  2NQV A;  3K6A A;  3OI9 A;  1IW7 D;  5ERT A;  4UUX A;  3TCR A;  2NQS A;  2PBQ A;  1WU2 A;  2G2C A;  1XI8 A;  4LHB A;  1EAV A;  5ERR A;  1G8L A;  4PD0 A;  4XCW A;  3MCI A;  4CTA A;  2FTS A;  5ERQ A;  3PZY A;  4CTA B;  3MCH A;  2NQN A;  1IHC A;  4U90 A;  4CT8 A;  5ERS A;  5G2R A;  1UZ5 A;  4U91 A; 
#chains in the Genus database with same CATH homology
 2NQR A;  2F7W A;  1O8N A;  3MCJ A;  4CT9 A;  1Y5E A;  1DI7 A;  1O8Q A;  4UUW A;  4PD1 A;  2NQU A;  2NQQ A;  2NRS A;  2NQM A;  2F7Y A;  2NQK A;  2IS8 A;  1JLJ A;  1MKZ A;  4TK1 A;  2NRP A;  1HQM D;  3RFQ A;  3KBQ A;  1DI6 A;  2G4R A;  5ERV A;  4TK4 A;  4TK3 A;  1UUY A;  4TWG A;  3IWT A;  4UOC A;  5D6G A;  5D8H B;  3JSY A;  2X3L A;  2QQ1 A;  1FC5 A;  1I6V D;  5ERU A;  2NRO A;  1UUX A;  1R2K A;  1O8O A;  4NWB A;  1T3E A;  5G2S A;  1G8R A;  2FU3 A;  4NWO A;  2NQV A;  3K6A A;  3OI9 A;  1IW7 D;  5ERT A;  4UUX A;  3TCR A;  2NQS A;  2PBQ A;  1WU2 A;  2G2C A;  1XI8 A;  4LHB A;  1EAV A;  5ERR A;  1G8L A;  4PD0 A;  4XCW A;  3MCI A;  4CTA A;  2FTS A;  5ERQ A;  3PZY A;  4CTA B;  3MCH A;  2NQN A;  1IHC A;  4U90 A;  4CT8 A;  5ERS A;  5G2R A;  1UZ5 A;  4U91 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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