5ERRA

Gephe in complex with mg(2+) - adp
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
418
structure length
414
Chain Sequence
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 104
structure length 414
sequence length 418
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5errA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5errA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5errA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5errA02
4U91A 2QQ1A 1XI8A 2NQNA 2NRPA 3TCRA 2F7WA 2FU3A 2FTSA 1EAVA 4PD1A 1FC5A 1Y5EA 2NQKA 4TK4A 2G4RA 3RFQA 4CTAA 2NQRA 4CT8A 3IWTA 2PBQA 4UUWA 5ERUA 1UUXA 4TWGA 2NQSA 1UUYA 2IS8A 2F7YA 3K6AA 5ERTA 4TK3A 4UOCA 3PZYA 3OI9A 4XCWA 2NQUA 5ERVA 1T3EA 1O8NA 1G8RA 4U90A 2NRSA 4LHBA 4UUXA 2NQQA 1O8OA 5ERSA 2NQVA 1O8QA 1MKZA 3MCIA 2NROA 4CT9A 3KBQA 5ERRA 2NQMA 4CTAB 1UZ5A 1JLJA 4TK1A 2X3LA 1R2KA 2G2CA 3MCHA 1WU2A 1DI6A 4NWOA 3MCJA 4PD0A 5G2RA 1DI7A 1G8LA 5G2SA 1IHCA 5ERQA
chains in the Genus database with same CATH superfamily
4U91A 2QQ1A 1XI8A 2NQNA 2NRPA 3TCRA 2F7WA 2FU3A 1YZYA 2FTSA 5DMHA 1EAVA 4PD1A 1FC5A 1Y5EA 2NQKA 4TK4A 2G4RA 3RFQA 4CTAA 2NQRA 5D8HB 4NWBA 4CT8A 3IWTA 2PBQA 4UUWA 1I6VD 5ERUA 3DQQA 1UUXA 4TWGA 2NQSA 1UUYA 2IS8A 2F7YA 3K6AA 5ERTA 4TK3A 5D6GA 4UOCA 3PZYA 3OI9A 4XCWA 2NQUA 3JSYA 5ERVA 1T3EA 1O8NA 1G8RA 4U90A 2NRSA 4LHBA 4UUXA 2NQQA 1O8OA 5ERSA 1HQMD 2NQVA 1O8QA 1MKZA 3MCIA 2NROA 1IW7D 4CT9A 3KBQA 5ERRA 2NQMA 4CTAB 1UZ5A 1JLJA 4TK1A 2X3LA 1R2KA 2G2CA 3MCHA 1WU2A 1DI6A 4NWOA 3MCJA 4PD0A 5G2RA 1DI7A 1G8LA 5G2SA 1IHCA 5ERQA
chains in the Genus database with same CATH topology
4U91A 2QQ1A 1XI8A 2NQNA 2NRPA 3TCRA 2F7WA 2FU3A 2FTSA 1EAVA 4PD1A 1FC5A 1Y5EA 2NQKA 4TK4A 2G4RA 3RFQA 4CTAA 2NQRA 5D8HB 4NWBA 4CT8A 3IWTA 2PBQA 4UUWA 1I6VD 5ERUA 1UUXA 4TWGA 2NQSA 1UUYA 2IS8A 2F7YA 3K6AA 5ERTA 4TK3A 5D6GA 4UOCA 3PZYA 3OI9A 4XCWA 2NQUA 3JSYA 5ERVA 1T3EA 1O8NA 1G8RA 4U90A 2NRSA 4LHBA 4UUXA 2NQQA 1O8OA 5ERSA 1HQMD 2NQVA 1O8QA 1MKZA 3MCIA 2NROA 1IW7D 4CT9A 3KBQA 5ERRA 2NQMA 4CTAB 1UZ5A 1JLJA 4TK1A 2X3LA 1R2KA 2G2CA 3MCHA 1WU2A 1DI6A 4NWOA 3MCJA 4PD0A 5G2RA 1DI7A 1G8LA 5G2SA 1IHCA 5ERQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U91 A;  2QQ1 A;  1XI8 A;  2NQN A;  2NRP A;  3TCR A;  2F7W A;  2FU3 A;  2FTS A;  1EAV A;  4PD1 A;  1FC5 A;  1Y5E A;  2NQK A;  4TK4 A;  2G4R A;  3RFQ A;  4CTA A;  2NQR A;  4CT8 A;  3IWT A;  2PBQ A;  4UUW A;  5ERU A;  1UUX A;  4TWG A;  2NQS A;  1UUY A;  2IS8 A;  2F7Y A;  3K6A A;  5ERT A;  4TK3 A;  4UOC A;  3PZY A;  3OI9 A;  4XCW A;  2NQU A;  5ERV A;  1T3E A;  1O8N A;  1G8R A;  4U90 A;  2NRS A;  4LHB A;  4UUX A;  2NQQ A;  1O8O A;  5ERS A;  2NQV A;  1O8Q A;  1MKZ A;  3MCI A;  2NRO A;  4CT9 A;  3KBQ A;  5ERR A;  2NQM A;  4CTA B;  1UZ5 A;  1JLJ A;  4TK1 A;  2X3L A;  1R2K A;  2G2C A;  3MCH A;  1WU2 A;  1DI6 A;  4NWO A;  3MCJ A;  4PD0 A;  5G2R A;  1DI7 A;  1G8L A;  5G2S A;  1IHC A;  5ERQ A; 
#chains in the Genus database with same CATH topology
 4U91 A;  2QQ1 A;  1XI8 A;  2NQN A;  2NRP A;  3TCR A;  2F7W A;  2FU3 A;  1YZY A;  2FTS A;  5DMH A;  1EAV A;  4PD1 A;  1FC5 A;  1Y5E A;  2NQK A;  4TK4 A;  2G4R A;  3RFQ A;  4CTA A;  2NQR A;  5D8H B;  4NWB A;  4CT8 A;  3IWT A;  2PBQ A;  4UUW A;  1I6V D;  5ERU A;  3DQQ A;  1UUX A;  4TWG A;  2NQS A;  1UUY A;  2IS8 A;  2F7Y A;  3K6A A;  5ERT A;  4TK3 A;  5D6G A;  4UOC A;  3PZY A;  3OI9 A;  4XCW A;  2NQU A;  3JSY A;  5ERV A;  1T3E A;  1O8N A;  1G8R A;  4U90 A;  2NRS A;  4LHB A;  4UUX A;  2NQQ A;  1O8O A;  5ERS A;  1HQM D;  2NQV A;  1O8Q A;  1MKZ A;  3MCI A;  2NRO A;  1IW7 D;  4CT9 A;  3KBQ A;  5ERR A;  2NQM A;  4CTA B;  1UZ5 A;  1JLJ A;  4TK1 A;  2X3L A;  1R2K A;  2G2C A;  3MCH A;  1WU2 A;  1DI6 A;  4NWO A;  3MCJ A;  4PD0 A;  5G2R A;  1DI7 A;  1G8L A;  5G2S A;  1IHC A;  5ERQ A; 
#chains in the Genus database with same CATH homology
 4U91 A;  2QQ1 A;  1XI8 A;  2NQN A;  2NRP A;  3TCR A;  2F7W A;  2FU3 A;  2FTS A;  1EAV A;  4PD1 A;  1FC5 A;  1Y5E A;  2NQK A;  4TK4 A;  2G4R A;  3RFQ A;  4CTA A;  2NQR A;  5D8H B;  4NWB A;  4CT8 A;  3IWT A;  2PBQ A;  4UUW A;  1I6V D;  5ERU A;  1UUX A;  4TWG A;  2NQS A;  1UUY A;  2IS8 A;  2F7Y A;  3K6A A;  5ERT A;  4TK3 A;  5D6G A;  4UOC A;  3PZY A;  3OI9 A;  4XCW A;  2NQU A;  3JSY A;  5ERV A;  1T3E A;  1O8N A;  1G8R A;  4U90 A;  2NRS A;  4LHB A;  4UUX A;  2NQQ A;  1O8O A;  5ERS A;  1HQM D;  2NQV A;  1O8Q A;  1MKZ A;  3MCI A;  2NRO A;  1IW7 D;  4CT9 A;  3KBQ A;  5ERR A;  2NQM A;  4CTA B;  1UZ5 A;  1JLJ A;  4TK1 A;  2X3L A;  1R2K A;  2G2C A;  3MCH A;  1WU2 A;  1DI6 A;  4NWO A;  3MCJ A;  4PD0 A;  5G2R A;  1DI7 A;  1G8L A;  5G2S A;  1IHC A;  5ERQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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