5ERVA

Ternary complex of gephe - adp - tungsten cluster
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
418
structure length
413
Chain Sequence
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Rattus norvegicus
publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule keywords Gephyrin
total genus 103
structure length 413
sequence length 418
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5ervA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5ervA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5ervA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5ervA02
4CTAA 4PD1A 2NQKA 2NQRA 1DI6A 5ERUA 4CT8A 3PZYA 5G2RA 1WU2A 4TWGA 1O8QA 4XCWA 1FC5A 4TK4A 4LHBA 1UUXA 2G2CA 2NQVA 1UUYA 3KBQA 3RFQA 2FU3A 3K6AA 5ERVA 2F7YA 2QQ1A 4UOCA 2NQMA 5G2SA 2NQNA 3MCJA 3IWTA 2NRPA 1JLJA 3MCHA 1G8RA 1O8OA 5ERRA 5ERSA 4PD0A 1EAVA 1Y5EA 2NQQA 4U90A 2G4RA 2X3LA 4CT9A 1T3EA 5ERQA 1XI8A 3OI9A 2NQSA 5ERTA 4NWOA 4U91A 2NRSA 1R2KA 1O8NA 4CTAB 2FTSA 1G8LA 1DI7A 3MCIA 2IS8A 4TK3A 3TCRA 4TK1A 1MKZA 4UUWA 1UZ5A 4UUXA 2F7WA 2PBQA 1IHCA 2NQUA 2NROA
chains in the Genus database with same CATH superfamily
4CTAA 4PD1A 2NQKA 2NQRA 3JSYA 1DI6A 5ERUA 4CT8A 3PZYA 5G2RA 1WU2A 4TWGA 1O8QA 4XCWA 1FC5A 4TK4A 4LHBA 5DMHA 1UUXA 2G2CA 2NQVA 1UUYA 3KBQA 3RFQA 2FU3A 1I6VD 3K6AA 5ERVA 2F7YA 2QQ1A 4UOCA 2NQMA 4NWBA 5G2SA 2NQNA 3MCJA 3IWTA 3DQQA 2NRPA 1JLJA 3MCHA 1G8RA 1O8OA 5ERRA 5ERSA 4PD0A 1EAVA 1Y5EA 2NQQA 2NROA 4U90A 2G4RA 2X3LA 4CT9A 1T3EA 5ERQA 1XI8A 3OI9A 2NQSA 5ERTA 4NWOA 4U91A 2NRSA 1R2KA 1O8NA 5D8HB 4CTAB 2FTSA 1G8LA 1DI7A 3MCIA 2IS8A 4TK3A 3TCRA 4TK1A 1MKZA 4UUWA 1IW7D 1UZ5A 4UUXA 1HQMD 5D6GA 2F7WA 2PBQA 1IHCA 2NQUA 1YZYA
chains in the Genus database with same CATH topology
4CTAA 4PD1A 2NQKA 2NQRA 3JSYA 1DI6A 5ERUA 4CT8A 3PZYA 5G2RA 1WU2A 4TWGA 1O8QA 4XCWA 1FC5A 4TK4A 4LHBA 1UUXA 2G2CA 2NQVA 1UUYA 3KBQA 3RFQA 2FU3A 1I6VD 3K6AA 5ERVA 2F7YA 2QQ1A 4UOCA 2NQMA 4NWBA 5G2SA 2NQNA 3MCJA 3IWTA 2NRPA 1JLJA 3MCHA 1G8RA 1O8OA 5ERRA 5ERSA 4PD0A 1EAVA 1Y5EA 2NQQA 4U90A 2G4RA 2X3LA 4CT9A 1T3EA 5ERQA 1XI8A 3OI9A 2NQSA 5ERTA 4NWOA 4U91A 2NRSA 1R2KA 1O8NA 5D8HB 4CTAB 2FTSA 1G8LA 1DI7A 3MCIA 2IS8A 4TK3A 3TCRA 4TK1A 1MKZA 4UUWA 1IW7D 1UZ5A 4UUXA 1HQMD 5D6GA 2F7WA 2PBQA 1IHCA 2NQUA 2NROA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CTA A;  4PD1 A;  2NQK A;  2NQR A;  1DI6 A;  5ERU A;  4CT8 A;  3PZY A;  5G2R A;  1WU2 A;  4TWG A;  1O8Q A;  4XCW A;  1FC5 A;  4TK4 A;  4LHB A;  1UUX A;  2G2C A;  2NQV A;  1UUY A;  3KBQ A;  3RFQ A;  2FU3 A;  3K6A A;  5ERV A;  2F7Y A;  2QQ1 A;  4UOC A;  2NQM A;  5G2S A;  2NQN A;  3MCJ A;  3IWT A;  2NRP A;  1JLJ A;  3MCH A;  1G8R A;  1O8O A;  5ERR A;  5ERS A;  4PD0 A;  1EAV A;  1Y5E A;  2NQQ A;  4U90 A;  2G4R A;  2X3L A;  4CT9 A;  1T3E A;  5ERQ A;  1XI8 A;  3OI9 A;  2NQS A;  5ERT A;  4NWO A;  4U91 A;  2NRS A;  1R2K A;  1O8N A;  4CTA B;  2FTS A;  1G8L A;  1DI7 A;  3MCI A;  2IS8 A;  4TK3 A;  3TCR A;  4TK1 A;  1MKZ A;  4UUW A;  1UZ5 A;  4UUX A;  2F7W A;  2PBQ A;  1IHC A;  2NQU A;  2NRO A; 
#chains in the Genus database with same CATH topology
 4CTA A;  4PD1 A;  2NQK A;  2NQR A;  3JSY A;  1DI6 A;  5ERU A;  4CT8 A;  3PZY A;  5G2R A;  1WU2 A;  4TWG A;  1O8Q A;  4XCW A;  1FC5 A;  4TK4 A;  4LHB A;  5DMH A;  1UUX A;  2G2C A;  2NQV A;  1UUY A;  3KBQ A;  3RFQ A;  2FU3 A;  1I6V D;  3K6A A;  5ERV A;  2F7Y A;  2QQ1 A;  4UOC A;  2NQM A;  4NWB A;  5G2S A;  2NQN A;  3MCJ A;  3IWT A;  3DQQ A;  2NRP A;  1JLJ A;  3MCH A;  1G8R A;  1O8O A;  5ERR A;  5ERS A;  4PD0 A;  1EAV A;  1Y5E A;  2NQQ A;  2NRO A;  4U90 A;  2G4R A;  2X3L A;  4CT9 A;  1T3E A;  5ERQ A;  1XI8 A;  3OI9 A;  2NQS A;  5ERT A;  4NWO A;  4U91 A;  2NRS A;  1R2K A;  1O8N A;  5D8H B;  4CTA B;  2FTS A;  1G8L A;  1DI7 A;  3MCI A;  2IS8 A;  4TK3 A;  3TCR A;  4TK1 A;  1MKZ A;  4UUW A;  1IW7 D;  1UZ5 A;  4UUX A;  1HQM D;  5D6G A;  2F7W A;  2PBQ A;  1IHC A;  2NQU A;  1YZY A; 
#chains in the Genus database with same CATH homology
 4CTA A;  4PD1 A;  2NQK A;  2NQR A;  3JSY A;  1DI6 A;  5ERU A;  4CT8 A;  3PZY A;  5G2R A;  1WU2 A;  4TWG A;  1O8Q A;  4XCW A;  1FC5 A;  4TK4 A;  4LHB A;  1UUX A;  2G2C A;  2NQV A;  1UUY A;  3KBQ A;  3RFQ A;  2FU3 A;  1I6V D;  3K6A A;  5ERV A;  2F7Y A;  2QQ1 A;  4UOC A;  2NQM A;  4NWB A;  5G2S A;  2NQN A;  3MCJ A;  3IWT A;  2NRP A;  1JLJ A;  3MCH A;  1G8R A;  1O8O A;  5ERR A;  5ERS A;  4PD0 A;  1EAV A;  1Y5E A;  2NQQ A;  4U90 A;  2G4R A;  2X3L A;  4CT9 A;  1T3E A;  5ERQ A;  1XI8 A;  3OI9 A;  2NQS A;  5ERT A;  4NWO A;  4U91 A;  2NRS A;  1R2K A;  1O8N A;  5D8H B;  4CTA B;  2FTS A;  1G8L A;  1DI7 A;  3MCI A;  2IS8 A;  4TK3 A;  3TCR A;  4TK1 A;  1MKZ A;  4UUW A;  1IW7 D;  1UZ5 A;  4UUX A;  1HQM D;  5D6G A;  2F7W A;  2PBQ A;  1IHC A;  2NQU A;  2NRO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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