5ERVA

Ternary complex of gephe - adp - tungsten cluster
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
418
structure length
413
Chain Sequence
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Rattus norvegicus
publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule keywords Gephyrin
total genus 103
structure length 413
sequence length 418
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5ervA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5ervA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5ervA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5ervA02
3PZYA 1WU2A 4UUXA 4UUWA 1Y5EA 2NQMA 1O8OA 2NQSA 1UUXA 4TK4A 2NRSA 2G2CA 2FU3A 2NQQA 2G4RA 1O8NA 4NWOA 5ERVA 3KBQA 1UUYA 2QQ1A 4TK1A 4CTAA 4CT9A 4CTAB 3MCIA 1IHCA 2NQNA 1FC5A 3MCJA 5ERTA 2F7YA 2NQRA 5ERUA 2NQVA 1O8QA 1MKZA 4TK3A 2FTSA 3RFQA 4CT8A 4PD1A 2F7WA 2X3LA 3K6AA 1DI6A 2NROA 1T3EA 5ERRA 4TWGA 2IS8A 1DI7A 4XCWA 1JLJA 1XI8A 2NQKA 1G8LA 3MCHA 2NQUA 1R2KA 2NRPA 3OI9A 4U91A 4UOCA 5G2SA 1UZ5A 1G8RA 5ERQA 4PD0A 2PBQA 4LHBA 4U90A 3IWTA 5G2RA 3TCRA 5ERSA 1EAVA
chains in the Genus database with same CATH superfamily
3PZYA 1WU2A 4UUXA 1IW7D 1YZYA 4UUWA 1Y5EA 5D6GA 2NQMA 1O8OA 2NQSA 1UUXA 4TK4A 2NRSA 2G2CA 2FU3A 2NQQA 2G4RA 1O8NA 4NWOA 5ERVA 3KBQA 1UUYA 2QQ1A 1I6VD 4TK1A 3DQQA 1HQMD 4CTAA 4CT9A 4CTAB 3MCIA 1IHCA 2NQNA 1FC5A 3MCJA 5ERTA 2F7YA 2NQRA 5ERUA 2NQVA 1O8QA 1MKZA 3JSYA 4TK3A 2FTSA 3RFQA 4CT8A 4PD1A 2F7WA 2X3LA 3K6AA 1DI6A 2NROA 1T3EA 5ERRA 4TWGA 5DMHA 5D8HB 2IS8A 1DI7A 4XCWA 1JLJA 1XI8A 2NQKA 1G8LA 3MCHA 2NQUA 1R2KA 2NRPA 3OI9A 4U91A 4UOCA 4NWBA 5G2SA 1UZ5A 1G8RA 5ERQA 4PD0A 2PBQA 4LHBA 4U90A 3IWTA 5G2RA 3TCRA 5ERSA 1EAVA
chains in the Genus database with same CATH topology
3PZYA 1WU2A 4UUXA 1IW7D 4UUWA 1Y5EA 5D6GA 2NQMA 1O8OA 2NQSA 1UUXA 4TK4A 2NRSA 2G2CA 2FU3A 2NQQA 2G4RA 1O8NA 4NWOA 5ERVA 3KBQA 1UUYA 2QQ1A 1I6VD 4TK1A 1HQMD 4CTAA 4CT9A 4CTAB 3MCIA 1IHCA 2NQNA 1FC5A 3MCJA 5ERTA 2F7YA 2NQRA 5ERUA 2NQVA 1O8QA 1MKZA 3JSYA 4TK3A 2FTSA 3RFQA 4CT8A 4PD1A 2F7WA 2X3LA 3K6AA 1DI6A 2NROA 1T3EA 5ERRA 4TWGA 5D8HB 2IS8A 1DI7A 4XCWA 1JLJA 1XI8A 2NQKA 1G8LA 3MCHA 2NQUA 1R2KA 2NRPA 3OI9A 4U91A 4UOCA 4NWBA 5G2SA 1UZ5A 1G8RA 5ERQA 4PD0A 2PBQA 4LHBA 4U90A 3IWTA 5G2RA 3TCRA 5ERSA 1EAVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PZY A;  1WU2 A;  4UUX A;  4UUW A;  1Y5E A;  2NQM A;  1O8O A;  2NQS A;  1UUX A;  4TK4 A;  2NRS A;  2G2C A;  2FU3 A;  2NQQ A;  2G4R A;  1O8N A;  4NWO A;  5ERV A;  3KBQ A;  1UUY A;  2QQ1 A;  4TK1 A;  4CTA A;  4CT9 A;  4CTA B;  3MCI A;  1IHC A;  2NQN A;  1FC5 A;  3MCJ A;  5ERT A;  2F7Y A;  2NQR A;  5ERU A;  2NQV A;  1O8Q A;  1MKZ A;  4TK3 A;  2FTS A;  3RFQ A;  4CT8 A;  4PD1 A;  2F7W A;  2X3L A;  3K6A A;  1DI6 A;  2NRO A;  1T3E A;  5ERR A;  4TWG A;  2IS8 A;  1DI7 A;  4XCW A;  1JLJ A;  1XI8 A;  2NQK A;  1G8L A;  3MCH A;  2NQU A;  1R2K A;  2NRP A;  3OI9 A;  4U91 A;  4UOC A;  5G2S A;  1UZ5 A;  1G8R A;  5ERQ A;  4PD0 A;  2PBQ A;  4LHB A;  4U90 A;  3IWT A;  5G2R A;  3TCR A;  5ERS A;  1EAV A; 
#chains in the Genus database with same CATH topology
 3PZY A;  1WU2 A;  4UUX A;  1IW7 D;  1YZY A;  4UUW A;  1Y5E A;  5D6G A;  2NQM A;  1O8O A;  2NQS A;  1UUX A;  4TK4 A;  2NRS A;  2G2C A;  2FU3 A;  2NQQ A;  2G4R A;  1O8N A;  4NWO A;  5ERV A;  3KBQ A;  1UUY A;  2QQ1 A;  1I6V D;  4TK1 A;  3DQQ A;  1HQM D;  4CTA A;  4CT9 A;  4CTA B;  3MCI A;  1IHC A;  2NQN A;  1FC5 A;  3MCJ A;  5ERT A;  2F7Y A;  2NQR A;  5ERU A;  2NQV A;  1O8Q A;  1MKZ A;  3JSY A;  4TK3 A;  2FTS A;  3RFQ A;  4CT8 A;  4PD1 A;  2F7W A;  2X3L A;  3K6A A;  1DI6 A;  2NRO A;  1T3E A;  5ERR A;  4TWG A;  5DMH A;  5D8H B;  2IS8 A;  1DI7 A;  4XCW A;  1JLJ A;  1XI8 A;  2NQK A;  1G8L A;  3MCH A;  2NQU A;  1R2K A;  2NRP A;  3OI9 A;  4U91 A;  4UOC A;  4NWB A;  5G2S A;  1UZ5 A;  1G8R A;  5ERQ A;  4PD0 A;  2PBQ A;  4LHB A;  4U90 A;  3IWT A;  5G2R A;  3TCR A;  5ERS A;  1EAV A; 
#chains in the Genus database with same CATH homology
 3PZY A;  1WU2 A;  4UUX A;  1IW7 D;  4UUW A;  1Y5E A;  5D6G A;  2NQM A;  1O8O A;  2NQS A;  1UUX A;  4TK4 A;  2NRS A;  2G2C A;  2FU3 A;  2NQQ A;  2G4R A;  1O8N A;  4NWO A;  5ERV A;  3KBQ A;  1UUY A;  2QQ1 A;  1I6V D;  4TK1 A;  1HQM D;  4CTA A;  4CT9 A;  4CTA B;  3MCI A;  1IHC A;  2NQN A;  1FC5 A;  3MCJ A;  5ERT A;  2F7Y A;  2NQR A;  5ERU A;  2NQV A;  1O8Q A;  1MKZ A;  3JSY A;  4TK3 A;  2FTS A;  3RFQ A;  4CT8 A;  4PD1 A;  2F7W A;  2X3L A;  3K6A A;  1DI6 A;  2NRO A;  1T3E A;  5ERR A;  4TWG A;  5D8H B;  2IS8 A;  1DI7 A;  4XCW A;  1JLJ A;  1XI8 A;  2NQK A;  1G8L A;  3MCH A;  2NQU A;  1R2K A;  2NRP A;  3OI9 A;  4U91 A;  4UOC A;  4NWB A;  5G2S A;  1UZ5 A;  1G8R A;  5ERQ A;  4PD0 A;  2PBQ A;  4LHB A;  4U90 A;  3IWT A;  5G2R A;  3TCR A;  5ERS A;  1EAV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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