5GKCA

The crystal structure of the cps-6 h148a/f122a
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
242
structure length
238
Chain Sequence
GSPSRSAEIMKHGYPGFTNVRTYEDFVLSYDYKTRTAHWVCEHLTPERLKVDRKLCEAKPDITFPQKFLSQNTDYKCSGFDRGALAAAGNHRKSQLAVDQTFYLSNMSPQVGRGFNRDKWNDLEMHCRRVAKKMINSYIITGPLYLPKLEGDGKKYIKYQVIGDNNVAVPTHFFKVALFEVTPGKFELESYILPNAVIEDTVEISKFHVPLDAVERSAGLEIFARLDPKSIVKENGAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
pubmed doi rcsb
molecule tags Hydrolase
source organism Caenorhabditis elegans
molecule keywords Endonuclease G, mitochondrial
total genus 70
structure length 238
sequence length 242
chains with identical sequence B
ec nomenclature ec 3.1.30.-:
pdb deposition date 2016-07-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 5gkcA00
4ZGAA 3NKOA 2XH3A 5DLTA 4E3YA 5L0EA 1QAEA 3WAVA 4GTXA 5INHA 3NKQA 5IJSA 4GTWA 4QH0A 2XR9A 3ISMA 3NKMA 3NKPA 5HRTA 3WAYA 2O3BA 2XRGA 5DLWA 5LQQA 4B56A 1ZM8A 5DLVA 5GKPA 1QL0A 4A1NA 4GTZA 5IJQA 5KXAA 3OWVA 5LIAA 4QN0A 4QGOA 3NKRA 3NKNA 4ZG6A 4GTYA 3WAWA 1G8TA 4ZG7A 5GKCA 3WAXA 5L0KA 5L0BA 3S5BA 4ZG9A 2XGRA 1SMNA
chains in the Genus database with same CATH superfamily
4ZGAA 3NKOA 2XH3A 5DLTA 4E3YA 5L0EA 1QAEA 3WAVA 4GTXA 5INHA 3NKQA 5IJSA 4GTWA 4QH0A 2XR9A 3ISMA 3NKMA 3NKPA 5HRTA 3WAYA 2O3BA 2XRGA 5DLWA 5LQQA 4B56A 1ZM8A 5DLVA 5GKPA 1QL0A 4A1NA 4GTZA 5IJQA 5KXAA 3OWVA 5LIAA 4QN0A 4QGOA 3NKRA 3NKNA 4ZG6A 4GTYA 3WAWA 1G8TA 4ZG7A 5GKCA 3WAXA 5L0KA 5L0BA 3S5BA 4ZG9A 2XGRA 1SMNA
chains in the Genus database with same CATH topology
4ZGAA 3NKOA 2XH3A 5DLTA 4E3YA 5L0EA 1QAEA 3WAVA 4GTXA 5INHA 3NKQA 5IJSA 4GTWA 4QH0A 2XR9A 3ISMA 3NKMA 3NKPA 5HRTA 3WAYA 2O3BA 2XRGA 5DLWA 5LQQA 4B56A 1ZM8A 5DLVA 5GKPA 1QL0A 4A1NA 4GTZA 5IJQA 5KXAA 3OWVA 5LIAA 4QN0A 4QGOA 3NKRA 3NKNA 4ZG6A 4GTYA 3WAWA 1G8TA 4ZG7A 5GKCA 3WAXA 5L0KA 5L0BA 3S5BA 4ZG9A 2XGRA 1SMNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZGA A;  3NKO A;  2XH3 A;  5DLT A;  4E3Y A;  5L0E A;  1QAE A;  3WAV A;  4GTX A;  5INH A;  3NKQ A;  5IJS A;  4GTW A;  4QH0 A;  2XR9 A;  3ISM A;  3NKM A;  3NKP A;  5HRT A;  3WAY A;  2O3B A;  2XRG A;  5DLW A;  5LQQ A;  4B56 A;  1ZM8 A;  5DLV A;  5GKP A;  1QL0 A;  4A1N A;  4GTZ A;  5IJQ A;  5KXA A;  3OWV A;  5LIA A;  4QN0 A;  4QGO A;  3NKR A;  3NKN A;  4ZG6 A;  4GTY A;  3WAW A;  1G8T A;  4ZG7 A;  5GKC A;  3WAX A;  5L0K A;  5L0B A;  3S5B A;  4ZG9 A;  2XGR A;  1SMN A; 
#chains in the Genus database with same CATH topology
 4ZGA A;  3NKO A;  2XH3 A;  5DLT A;  4E3Y A;  5L0E A;  1QAE A;  3WAV A;  4GTX A;  5INH A;  3NKQ A;  5IJS A;  4GTW A;  4QH0 A;  2XR9 A;  3ISM A;  3NKM A;  3NKP A;  5HRT A;  3WAY A;  2O3B A;  2XRG A;  5DLW A;  5LQQ A;  4B56 A;  1ZM8 A;  5DLV A;  5GKP A;  1QL0 A;  4A1N A;  4GTZ A;  5IJQ A;  5KXA A;  3OWV A;  5LIA A;  4QN0 A;  4QGO A;  3NKR A;  3NKN A;  4ZG6 A;  4GTY A;  3WAW A;  1G8T A;  4ZG7 A;  5GKC A;  3WAX A;  5L0K A;  5L0B A;  3S5B A;  4ZG9 A;  2XGR A;  1SMN A; 
#chains in the Genus database with same CATH homology
 4ZGA A;  3NKO A;  2XH3 A;  5DLT A;  4E3Y A;  5L0E A;  1QAE A;  3WAV A;  4GTX A;  5INH A;  3NKQ A;  5IJS A;  4GTW A;  4QH0 A;  2XR9 A;  3ISM A;  3NKM A;  3NKP A;  5HRT A;  3WAY A;  2O3B A;  2XRG A;  5DLW A;  5LQQ A;  4B56 A;  1ZM8 A;  5DLV A;  5GKP A;  1QL0 A;  4A1N A;  4GTZ A;  5IJQ A;  5KXA A;  3OWV A;  5LIA A;  4QN0 A;  4QGO A;  3NKR A;  3NKN A;  4ZG6 A;  4GTY A;  3WAW A;  1G8T A;  4ZG7 A;  5GKC A;  3WAX A;  5L0K A;  5L0B A;  3S5B A;  4ZG9 A;  2XGR A;  1SMN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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