5ERUA

Ternary complex of gephe - adp - molybdenum cluster
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
418
structure length
414
Chain Sequence
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 106
structure length 414
sequence length 418
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5eruA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5eruA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5eruA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5eruA02
1G8LA 1UUXA 5ERSA 3MCHA 1O8QA 1IHCA 2FTSA 1UUYA 2PBQA 1WU2A 2G4RA 2NQVA 3PZYA 3RFQA 2NRPA 2X3LA 4CTAB 5ERQA 1MKZA 5G2RA 3MCIA 5ERTA 3IWTA 1O8NA 4CT9A 5ERRA 2NQMA 1DI6A 1DI7A 3K6AA 2QQ1A 2G2CA 2NQNA 2NQRA 1O8OA 4PD0A 5ERVA 2FU3A 2NRSA 4TK1A 2NQUA 1Y5EA 1EAVA 4UUXA 4TWGA 2F7WA 1T3EA 4U90A 4U91A 1FC5A 3TCRA 2NQSA 1G8RA 4NWOA 2NROA 1JLJA 1R2KA 2F7YA 4UUWA 4UOCA 3MCJA 1UZ5A 2IS8A 5ERUA 4CT8A 4LHBA 4CTAA 4XCWA 4PD1A 1XI8A 4TK4A 2NQKA 5G2SA 3OI9A 3KBQA 4TK3A 2NQQA
chains in the Genus database with same CATH superfamily
1G8LA 1UUXA 1HQMD 5ERSA 3MCHA 1O8QA 1IHCA 2FTSA 1UUYA 2PBQA 1WU2A 2G4RA 2NQVA 3PZYA 3RFQA 2NRPA 2X3LA 4CTAB 5ERQA 1MKZA 5G2RA 3MCIA 5ERTA 3IWTA 1O8NA 4CT9A 5ERRA 2NQMA 1DI6A 1DI7A 3K6AA 2QQ1A 2G2CA 2NQNA 2NQRA 1O8OA 4PD0A 4NWBA 5ERVA 2FU3A 2NRSA 4TK1A 1YZYA 2NQUA 1Y5EA 1EAVA 5DMHA 4UUXA 4TWGA 2F7WA 1T3EA 4U90A 4U91A 1FC5A 3DQQA 3TCRA 2NQSA 1G8RA 4NWOA 2NROA 1JLJA 1R2KA 2F7YA 1IW7D 4UUWA 4UOCA 3MCJA 1UZ5A 2IS8A 5D6GA 5D8HB 5ERUA 4CT8A 1I6VD 4LHBA 4CTAA 4XCWA 4PD1A 1XI8A 3JSYA 4TK4A 2NQKA 5G2SA 3OI9A 3KBQA 4TK3A 2NQQA
chains in the Genus database with same CATH topology
1G8LA 1UUXA 1HQMD 5ERSA 3MCHA 1O8QA 1IHCA 2FTSA 1UUYA 2PBQA 1WU2A 2G4RA 2NQVA 3PZYA 3RFQA 2NRPA 2X3LA 4CTAB 5ERQA 1MKZA 5G2RA 3MCIA 5ERTA 3IWTA 1O8NA 4CT9A 5ERRA 2NQMA 1DI6A 1DI7A 3K6AA 2QQ1A 2G2CA 2NQNA 2NQRA 1O8OA 4PD0A 4NWBA 5ERVA 2FU3A 2NRSA 4TK1A 2NQUA 1Y5EA 1EAVA 4UUXA 4TWGA 2F7WA 1T3EA 4U90A 4U91A 1FC5A 3TCRA 2NQSA 1G8RA 4NWOA 2NROA 1JLJA 1R2KA 2F7YA 1IW7D 4UUWA 4UOCA 3MCJA 1UZ5A 2IS8A 5D6GA 5D8HB 5ERUA 4CT8A 1I6VD 4LHBA 4CTAA 4XCWA 4PD1A 1XI8A 3JSYA 4TK4A 2NQKA 5G2SA 3OI9A 3KBQA 4TK3A 2NQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G8L A;  1UUX A;  5ERS A;  3MCH A;  1O8Q A;  1IHC A;  2FTS A;  1UUY A;  2PBQ A;  1WU2 A;  2G4R A;  2NQV A;  3PZY A;  3RFQ A;  2NRP A;  2X3L A;  4CTA B;  5ERQ A;  1MKZ A;  5G2R A;  3MCI A;  5ERT A;  3IWT A;  1O8N A;  4CT9 A;  5ERR A;  2NQM A;  1DI6 A;  1DI7 A;  3K6A A;  2QQ1 A;  2G2C A;  2NQN A;  2NQR A;  1O8O A;  4PD0 A;  5ERV A;  2FU3 A;  2NRS A;  4TK1 A;  2NQU A;  1Y5E A;  1EAV A;  4UUX A;  4TWG A;  2F7W A;  1T3E A;  4U90 A;  4U91 A;  1FC5 A;  3TCR A;  2NQS A;  1G8R A;  4NWO A;  2NRO A;  1JLJ A;  1R2K A;  2F7Y A;  4UUW A;  4UOC A;  3MCJ A;  1UZ5 A;  2IS8 A;  5ERU A;  4CT8 A;  4LHB A;  4CTA A;  4XCW A;  4PD1 A;  1XI8 A;  4TK4 A;  2NQK A;  5G2S A;  3OI9 A;  3KBQ A;  4TK3 A;  2NQQ A; 
#chains in the Genus database with same CATH topology
 1G8L A;  1UUX A;  1HQM D;  5ERS A;  3MCH A;  1O8Q A;  1IHC A;  2FTS A;  1UUY A;  2PBQ A;  1WU2 A;  2G4R A;  2NQV A;  3PZY A;  3RFQ A;  2NRP A;  2X3L A;  4CTA B;  5ERQ A;  1MKZ A;  5G2R A;  3MCI A;  5ERT A;  3IWT A;  1O8N A;  4CT9 A;  5ERR A;  2NQM A;  1DI6 A;  1DI7 A;  3K6A A;  2QQ1 A;  2G2C A;  2NQN A;  2NQR A;  1O8O A;  4PD0 A;  4NWB A;  5ERV A;  2FU3 A;  2NRS A;  4TK1 A;  1YZY A;  2NQU A;  1Y5E A;  1EAV A;  5DMH A;  4UUX A;  4TWG A;  2F7W A;  1T3E A;  4U90 A;  4U91 A;  1FC5 A;  3DQQ A;  3TCR A;  2NQS A;  1G8R A;  4NWO A;  2NRO A;  1JLJ A;  1R2K A;  2F7Y A;  1IW7 D;  4UUW A;  4UOC A;  3MCJ A;  1UZ5 A;  2IS8 A;  5D6G A;  5D8H B;  5ERU A;  4CT8 A;  1I6V D;  4LHB A;  4CTA A;  4XCW A;  4PD1 A;  1XI8 A;  3JSY A;  4TK4 A;  2NQK A;  5G2S A;  3OI9 A;  3KBQ A;  4TK3 A;  2NQQ A; 
#chains in the Genus database with same CATH homology
 1G8L A;  1UUX A;  1HQM D;  5ERS A;  3MCH A;  1O8Q A;  1IHC A;  2FTS A;  1UUY A;  2PBQ A;  1WU2 A;  2G4R A;  2NQV A;  3PZY A;  3RFQ A;  2NRP A;  2X3L A;  4CTA B;  5ERQ A;  1MKZ A;  5G2R A;  3MCI A;  5ERT A;  3IWT A;  1O8N A;  4CT9 A;  5ERR A;  2NQM A;  1DI6 A;  1DI7 A;  3K6A A;  2QQ1 A;  2G2C A;  2NQN A;  2NQR A;  1O8O A;  4PD0 A;  4NWB A;  5ERV A;  2FU3 A;  2NRS A;  4TK1 A;  2NQU A;  1Y5E A;  1EAV A;  4UUX A;  4TWG A;  2F7W A;  1T3E A;  4U90 A;  4U91 A;  1FC5 A;  3TCR A;  2NQS A;  1G8R A;  4NWO A;  2NRO A;  1JLJ A;  1R2K A;  2F7Y A;  1IW7 D;  4UUW A;  4UOC A;  3MCJ A;  1UZ5 A;  2IS8 A;  5D6G A;  5D8H B;  5ERU A;  4CT8 A;  1I6V D;  4LHB A;  4CTA A;  4XCW A;  4PD1 A;  1XI8 A;  3JSY A;  4TK4 A;  2NQK A;  5G2S A;  3OI9 A;  3KBQ A;  4TK3 A;  2NQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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