1CA1A

Alpha-toxin from clostridium perfringens
Total Genus 137
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
370
structure length
370
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKVIANGKVVVDKDINEWISGNSTYNIK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the key toxin in gas gangrene.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords ALPHA-TOXIN
total genus 137
structure length 370
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 1998-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1ca1A01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1ca1A02
2FFZA 5FB9A 1FGOA 1AK0A 2WY6A 3FG4A 3V92A 3BNDA 1RP1A 2PPLA 4CXOA 1Y4KA 1ETHA 3V98A 5FBFA 4CWMA 1YGEA 1QM6A 2P0MA 3FG1A 1JNQA 1FGMA 1FGTA 4QWTA 5FBDA 1NO3A 1P6EA 2FNQA 5FBBA 3SNGA 1LPBB 4CXVA 5FBAA 1ROVA 2IUKA 3PZWA 4JDGA 1BU8A 3CWZB 1LNHA 3FG3A 3BNEA 1LOXA 1F8NA 1GPLA 3W52A 3BNCA 1FGQA 5FBCA 1QMDA 4CXPA 1CA1A 1FGRA 3V99A 2WXTA 2IUJA 1IK3A 3VF1A 1AH7A 3BNBA 3O8YA 4DJ4A 5EEOA 2PVSA 1KHOA 1RRHA 1OLPA 2SBLA 1N8SA 1N8QA 2FGNA 1LPAB 2WXUA 4NREA 1P6DA 1P5XA 1W52X 2HUCA 5FBGA 1HPLA 4WHAA 1HU9A 1GYGA 2OXEA 1RRLA 4WFOA
chains in the Genus database with same CATH superfamily
2FFZA 5FB9A 1FGOA 1AK0A 2WY6A 3FG4A 3V92A 3BNDA 1RP1A 2PPLA 4CXOA 1Y4KA 1ETHA 3V98A 5FBFA 4CWMA 1YGEA 3U6GA 1QM6A 2P0MA 3IBZA 3FG1A 2QNGA 1JNQA 1FGMA 1FGTA 4QWTA 5FBDA 1NO3A 4QEYA 2LGEA 1P6EA 2FNQA 5FBBA 3SNGA 1LPBB 4CXVA 5FBAA 1ROVA 2IUKA 3PZWA 4JDGA 1BU8A 3CWZB 2XHHA 1LNHA 3FG3A 1LOXA 3BNEA 1F8NA 1GPLA 3W52A 3BNCA 1FGQA 5FBCA 1QMDA 4CXPA 1CA1A 1FGRA 2XFEA 3V99A 2WXTA 2IUJA 1IK3A 3VF1A 1AH7A 2LRGA 2QZ7A 3BNBA 3O8YA 2XFDA 4DJ4A 2KXVA 5EEOA 2PVSA 1KHOA 1RRHA 2LG7A 1OLPA 2SBLA 1N8SA 1N8QA 2FGNA 1LPAB 2WXUA 4NREA 2XHJA 1P6DA 1P5XA 1W52X 2HUCA 5FBGA 1HPLA 4WHAA 1HU9A 2KXTA 1GYGA 2OXEA 1RRLA 4WFOA
chains in the Genus database with same CATH topology
2FFZA 5FB9A 1FGOA 1AK0A 2WY6A 3FG4A 3V92A 3BNDA 1RP1A 2PPLA 4CXOA 1Y4KA 1ETHA 3V98A 5FBFA 4CWMA 1YGEA 1QM6A 2P0MA 3FG1A 1JNQA 1FGMA 1FGTA 4QWTA 5FBDA 1NO3A 1P6EA 2FNQA 5FBBA 3SNGA 1LPBB 4CXVA 5FBAA 1ROVA 2IUKA 3PZWA 4JDGA 1BU8A 3CWZB 1LNHA 3FG3A 3BNEA 1LOXA 1F8NA 1GPLA 3W52A 3BNCA 1FGQA 5FBCA 1QMDA 4CXPA 1CA1A 1FGRA 3V99A 2WXTA 2IUJA 1IK3A 3VF1A 1AH7A 3BNBA 3O8YA 4DJ4A 5EEOA 2PVSA 1KHOA 1RRHA 1OLPA 2SBLA 1N8SA 1N8QA 2FGNA 1LPAB 2WXUA 4NREA 1P6DA 1P5XA 1W52X 2HUCA 5FBGA 1HPLA 4WHAA 1HU9A 1GYGA 2OXEA 1RRLA 4WFOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FFZ A;  5FB9 A;  1FGO A;  1AK0 A;  2WY6 A;  3FG4 A;  3V92 A;  3BND A;  1RP1 A;  2PPL A;  4CXO A;  1Y4K A;  1ETH A;  3V98 A;  5FBF A;  4CWM A;  1YGE A;  1QM6 A;  2P0M A;  3FG1 A;  1JNQ A;  1FGM A;  1FGT A;  4QWT A;  5FBD A;  1NO3 A;  1P6E A;  2FNQ A;  5FBB A;  3SNG A;  1LPB B;  4CXV A;  5FBA A;  1ROV A;  2IUK A;  3PZW A;  4JDG A;  1BU8 A;  3CWZ B;  1LNH A;  3FG3 A;  3BNE A;  1LOX A;  1F8N A;  1GPL A;  3W52 A;  3BNC A;  1FGQ A;  5FBC A;  1QMD A;  4CXP A;  1CA1 A;  1FGR A;  3V99 A;  2WXT A;  2IUJ A;  1IK3 A;  3VF1 A;  1AH7 A;  3BNB A;  3O8Y A;  4DJ4 A;  5EEO A;  2PVS A;  1KHO A;  1RRH A;  1OLP A;  2SBL A;  1N8S A;  1N8Q A;  2FGN A;  1LPA B;  2WXU A;  4NRE A;  1P6D A;  1P5X A;  1W52 X;  2HUC A;  5FBG A;  1HPL A;  4WHA A;  1HU9 A;  1GYG A;  2OXE A;  1RRL A;  4WFO A; 
#chains in the Genus database with same CATH topology
 2FFZ A;  5FB9 A;  1FGO A;  1AK0 A;  2WY6 A;  3FG4 A;  3V92 A;  3BND A;  1RP1 A;  2PPL A;  4CXO A;  1Y4K A;  1ETH A;  3V98 A;  5FBF A;  4CWM A;  1YGE A;  3U6G A;  1QM6 A;  2P0M A;  3IBZ A;  3FG1 A;  2QNG A;  1JNQ A;  1FGM A;  1FGT A;  4QWT A;  5FBD A;  1NO3 A;  4QEY A;  2LGE A;  1P6E A;  2FNQ A;  5FBB A;  3SNG A;  1LPB B;  4CXV A;  5FBA A;  1ROV A;  2IUK A;  3PZW A;  4JDG A;  1BU8 A;  3CWZ B;  2XHH A;  1LNH A;  3FG3 A;  1LOX A;  3BNE A;  1F8N A;  1GPL A;  3W52 A;  3BNC A;  1FGQ A;  5FBC A;  1QMD A;  4CXP A;  1CA1 A;  1FGR A;  2XFE A;  3V99 A;  2WXT A;  2IUJ A;  1IK3 A;  3VF1 A;  1AH7 A;  2LRG A;  2QZ7 A;  3BNB A;  3O8Y A;  2XFD A;  4DJ4 A;  2KXV A;  5EEO A;  2PVS A;  1KHO A;  1RRH A;  2LG7 A;  1OLP A;  2SBL A;  1N8S A;  1N8Q A;  2FGN A;  1LPA B;  2WXU A;  4NRE A;  2XHJ A;  1P6D A;  1P5X A;  1W52 X;  2HUC A;  5FBG A;  1HPL A;  4WHA A;  1HU9 A;  2KXT A;  1GYG A;  2OXE A;  1RRL A;  4WFO A; 
#chains in the Genus database with same CATH homology
 2FFZ A;  5FB9 A;  1FGO A;  1AK0 A;  2WY6 A;  3FG4 A;  3V92 A;  3BND A;  1RP1 A;  2PPL A;  4CXO A;  1Y4K A;  1ETH A;  3V98 A;  5FBF A;  4CWM A;  1YGE A;  1QM6 A;  2P0M A;  3FG1 A;  1JNQ A;  1FGM A;  1FGT A;  4QWT A;  5FBD A;  1NO3 A;  1P6E A;  2FNQ A;  5FBB A;  3SNG A;  1LPB B;  4CXV A;  5FBA A;  1ROV A;  2IUK A;  3PZW A;  4JDG A;  1BU8 A;  3CWZ B;  1LNH A;  3FG3 A;  3BNE A;  1LOX A;  1F8N A;  1GPL A;  3W52 A;  3BNC A;  1FGQ A;  5FBC A;  1QMD A;  4CXP A;  1CA1 A;  1FGR A;  3V99 A;  2WXT A;  2IUJ A;  1IK3 A;  3VF1 A;  1AH7 A;  3BNB A;  3O8Y A;  4DJ4 A;  5EEO A;  2PVS A;  1KHO A;  1RRH A;  1OLP A;  2SBL A;  1N8S A;  1N8Q A;  2FGN A;  1LPA B;  2WXU A;  4NRE A;  1P6D A;  1P5X A;  1W52 X;  2HUC A;  5FBG A;  1HPL A;  4WHA A;  1HU9 A;  1GYG A;  2OXE A;  1RRL A;  4WFO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...